Presentation on Edible vaccine
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Presentation of Edible Vaccine, Properties of an edible vaccine, how to make an edible vaccine, and etc. An edible vaccine is the best vaccine for developing country because of it very cost effective and very simple to use. But our country has not developed this vaccine yet. So it is our responsibility to develop an edible vaccine to protect our human being form more infectious disease.
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Edible vaccine
Edible vaccineAsma Hossain
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Edible vaccines are genetically engineered foods that contain antigens to produce an immune response against infections and diseases. They are administered orally by eating the food and induce both mucosal and systemic immunity. The antigens in edible vaccines break down in the Peyer's patches and activate B-cells to produce antibodies that provide mucosal immunity. Edible vaccines have been explored for diseases like diabetes, cholera, malaria, and measles. They offer advantages like low-cost mass production and distribution without needing medical facilities but also have challenges in maintaining consistent dosages. Future prospects include approval by WHO and production of edible vaccines for other major diseases.Edible vaccines
Edible vaccinespriya mehta
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"edible vaccines": Vaccines or candidate vaccines derived from edible plants. Transgenic plants are used as recombinant protein production systems and the edible plant tissue functions as an oral vaccine. Edible vaccine
Edible vaccineapurvaanand08
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Edible vaccines are produced by genetically engineering plants and animals to contain antigens that trigger an immune response. When ingested, the antigens are delivered through the digestive system and taken up by immune cells to produce antibodies and memory cells, protecting against disease. Different plants have been studied for their ability to serve as edible vaccines, including potato, banana, rice and tomato. Each has advantages like ease of growth or administration, but also challenges like stability of antigens or variable dosing. Edible vaccines could provide a low-cost, easy to distribute method for vaccination programs in developing areas.Edible vaccine
Edible vaccineKAUSHAL SAHU
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Synopsis
Introduction
History
Definition
Need for edible vaccine
Plants normally used for production of
edible vaccine
Production
Mode of application
Advantages
Disadvantages
Application
Conclusion
ReferencesEdible vaccines
Edible vaccinesanurag chanda
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Edible vaccines produced in plants offer potential advantages over traditional vaccines. Plants can be engineered to produce vaccine antigens through stable integration into the plant genome, allowing plants like tobacco, potato, tomato and banana to serve as bioreactors for vaccine production. Orally delivered plant-based vaccines have been shown to induce both mucosal and systemic immune responses and overcome obstacles to oral delivery by protecting antigens in the plant cell wall during digestion. Research is underway to develop plant-based vaccines for diseases of bioterrorism concern by delivering antigens for pathogens like smallpox, anthrax and plague.Edible vaccines
Edible vaccinesBahauddin Zakariya University lahore
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This document discusses edible vaccines, which are plant-based oral vaccines. Edible vaccines were proposed in the 1990s as they are easy to administer, stable without refrigeration, and low-cost. They work by antigens in transgenic plants protecting antigens from digestion and triggering an immune response. Examples discussed include research on edible vaccines for malaria, measles, hepatitis B, and cholera using plants like potato, banana, rice and tobacco. While challenges remain, edible vaccines hold promise to low-cost vaccination globally in a heat-stable oral form.Edvac2015
Edvac2015anurag chanda
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Plants offer potential as production platforms for vaccines that can be delivered orally through consumption of edible plant tissues. This allows for safe, inexpensive, and easily administered vaccines, important for developing countries. Several plant species have been studied for vaccine production, with choices based on how the vaccine will be delivered. Plant-derived vaccines have shown ability to induce both mucosal and systemic immune responses by protecting antigens from stomach digestion. Potential advantages include low-cost edible administration without medical personnel, ease of storage, transport and use, and improved safety over traditional vaccines.Edible vaccines
Edible vaccinesEr Priyanka
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Edible vaccines involve introducing selected genes into plants to produce antigens. When consumed, the antigens are delivered through the digestive tract to immune cells to produce an immune response. Clinical trials show edible potatoes expressing antigens from ETEC, Norwalk virus, and hepatitis B produced protective antibody levels in participants. Edible vaccines could provide a low-cost, heat-stable, easy to administer option for vaccination programs in developing countries. However, public resistance to genetically modified foods and risks of transgenic contamination limit the future of edible vaccines.Edible vaccines
Edible vaccinesSakshi Saxena
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1) The presentation discusses edible vaccines, which are plant-derived oral vaccines that can help address issues with traditional vaccines like cost, need for medical personnel to administer, and unsafe needle reuse.
2) Experiments showed that mice and human volunteers developed an immune response and antibodies after eating transgenic plants engineered to express the hepatitis B surface antigen protein.
3) Edible vaccines could provide a low-cost, easy to administer alternative to traditional vaccines for developing countries and help prevent diseases in areas where access to medical facilities is limited. However, challenges with dosage consistency and stability need further research.Edible vaccine 
Edible vaccine sountharya Sen s
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Edible vaccines are genetically engineered foods that contain antigens that can provide active immune responses against infections and inflammation. They are easy to store, transport, and can induce both mucosal and systemic immune responses unlike injection vaccines. Candidate plants for edible vaccines include bananas, potatoes, lettuce, tomatoes, rice, wheat and soybeans. While edible vaccines promise a cost-effective and easy way to administer vaccines, challenges include variable dosage amounts, inconsistency between plants, and difficulty selecting the best candidate plant.Edible vaccines 2
Edible vaccines 2maria khatoon
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Edible vaccines use transgenic plants to produce antigens from pathogens that can induce an immune response when consumed. The antigen genes are inserted into plants using genetic engineering techniques. When the plant material is eaten, the antigens are released in the intestines and taken up by immune cells, triggering antibody production and immune memory against the pathogen. Some key advantages of edible vaccines are low cost of production and ease of distribution and administration compared to traditional vaccines. However, there are also safety and environmental risks associated with genetically modified crops that require further research. Overall, edible vaccines show promise as a cost-effective delivery method for immunization.Edible vaccine
Edible vaccineIIM Ahmedabad
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Edible vaccines use plants to produce vaccine proteins that are consumed to stimulate immunity. They could provide a cost-effective way to vaccinate remote populations by protecting vaccine proteins from digestion and triggering an immune response through the gut. However, dosage may vary and they are not suitable for infants. Safety issues around environmental contamination must also be addressed.Edible vaccines
Edible vaccinesSmit Bhadani
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This document provides information about edible vaccines. It begins by defining an ideal vaccine and then defines vaccines in general. It introduces the concept of edible vaccines, which are genetically engineered foods that express vaccine antigens to provide immunity. The document discusses the mechanisms of action, methods for transforming DNA into plants, candidate plant species, examples, factors affecting efficacy, applications, limitations, regulatory issues, recent discoveries, advantages and disadvantages, and future aspects of edible vaccines.edible vaccine
edible vaccineRekha Kumari
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Rekha presented on edible vaccines. Edible vaccines involve introducing genes from pathogens into plants to produce antigens. When consumed, these plant-based vaccines stimulate mucosal and systemic immunity. Various pathogens have been expressed in plants, including ETEC, cholera, Norwalk virus, hepatitis B, and measles. Advantages are oral delivery, lower costs, and stability without refrigeration. Challenges include ensuring consistent dosage and developing tolerance. Many organizations in India are researching edible vaccine candidates for diseases like malaria, tuberculosis, dengue, and hepatitis E.Sagar alone edible vaccine
Sagar alone edible vaccinesagar alone
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1. Edible vaccines work by introducing genes into food crops so that they produce vaccine antigens, which then stimulate an immune response when the plant is eaten.
2. Genes can be inserted through techniques like particle bombardment or Agrobacterium transformation, then the plant is grown and eaten to deliver the vaccine.
3. Clinical trials have explored edible vaccines for diseases like cholera, hepatitis B, rabies, and norovirus with some success in animal models.EDIBLE VACCINES
EDIBLE VACCINESP. G. Department of Botany, Berhampur University
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This document discusses edible vaccines, which are vaccines that can be administered orally by eating plants that have been genetically engineered to produce antigens. Edible vaccines are developed using methods like Agrobacterium transformation or gene gun methods to insert DNA encoding antigens into plants. Candidates for edible vaccines include crops like bananas, potatoes, and tomatoes that are engineered to produce antigens for diseases like hepatitis, malaria, measles, and diabetes. Edible vaccines offer advantages like reduced costs and ability to deliver multiple antigens orally, but also have limitations regarding stability and consistency of dosage.Edible Vaccines
Edible VaccinesSurbhiSharma196
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Edible vaccines are plant-based vaccines that are given orally. They were first tested on humans in 1997 using potatoes to deliver vaccines. Since then, many plant species like tobacco, tomatoes, and potatoes have been genetically engineered to produce vaccines for diseases like hepatitis B, cholera, norovirus, and rabies. Recent research has focused on developing edible vaccines for insects like honeybees and livestock like pigs. Advantages are low-cost production and inducing mucosal immunity through oral administration but challenges include variable dosage and immunotolerance.Ph02 edible vaccines
Ph02 edible vaccinesSrinivas Bhairy
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This document provides an overview of edible vaccines. It discusses how edible vaccines are produced by introducing genes encoding vaccine antigens into edible plants using transformation methods. The document outlines various plant species used for edible vaccines like tomatoes, rice, maize, potatoes, and tobacco. It discusses factors affecting the efficacy of edible vaccines and provides examples of edible vaccine research for diseases like malaria, measles, hepatitis B, norovirus, and Alzheimer's disease. The conclusion states that edible vaccines could improve vaccination programs in developing countries by reducing costs and need for cold storage.plant based vaccine
plant based vaccineSahar Khan
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This document discusses vaccines and the potential for using plants as bioreactors to produce vaccines. It notes that vaccines provide active immunity against diseases and typically contain weakened or killed forms of pathogens. Vaccination is an effective public health measure. Recently, genetically engineering plants to express antigen proteins from pathogens has emerged as a way to develop subunit vaccines more economically than traditional methods. The document outlines opportunities like safety, immune response, stability, low cost, and challenges like regulatory concerns for plant-based vaccines. It provides examples of plant-made influenza vaccines in development that could allow rapid production in response to pandemics.Plant Based Edible Vaccines
Plant Based Edible VaccinesBir Bahadur Thapa
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1. Plant-based edible vaccines produced in crops like bananas, potatoes, and tomatoes show promise as a cheap and effective way to deliver vaccines orally. Clinical trials have shown plant-based vaccines for diseases like cholera and E. coli infection can generate protective immune responses.
2. However, challenges remain regarding safety, dosage control, and public perception of genetically modified crops. Further research is still needed to optimize plant varieties and production methods before wide-scale use of edible vaccines.
3. While holding potential for improving global public health, particularly in developing areas, plant-based edible vaccines face regulatory hurdles and opposition related to their use of genetic engineering technologies.FOOD AS VACCINE 
FOOD AS VACCINE konatham teja kumar reddy
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Edible vaccines are plant- or animal-based vaccines that are ingested rather than injected. They were first developed in the 1990s as a cheaper alternative that doesn't require cold storage. Some early examples included transgenic potatoes and tomatoes that delivered antigens for E. coli and norovirus when eaten. Edible vaccines have advantages like low cost, easy delivery through eating, and no need for cold storage. However, they also have disadvantages like inconsistent dosage between plants and potential allergic reactions. The document discusses applications for edible malaria and hepatitis B vaccines and limitations like immune tolerance and stability.Edible vaccines
Edible vaccinesmasume jahed
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This document summarizes a seminar presentation on edible vaccines produced through molecular farming. It discusses isolating genes of interest and expressing them in plants, bacteria, yeast or mammalian cells. The outputs can include vaccines, therapeutics, and industrial products. Advantages of plant-based molecular farming include low production costs, safety, and ability to accurately fold complex proteins. Different types of edible vaccines are described, along with the history and production methods. Clinical trials and applications for treating infectious diseases, autoimmune diseases and cancer are also summarized.Edible vaccines
Edible vaccinesKalalSrilekha
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Edible vaccines are plant-based vaccines that are administered orally. They activate mucosal immunity and have several advantages over traditional injectable vaccines like lower cost, easier administration and storage, and activation of mucosal immunity. Common foods that have been engineered to produce edible vaccines include potatoes, lettuce, tobacco. Studies in humans and animals have shown that edible vaccines against diseases like diarrhea, hepatitis B, and measles can successfully induce immune responses and antibody production after oral administration.Plant vaccines
Plant vaccinesNikunj tyagi
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Plant-based vaccines, also known as edible vaccines, are produced through transgenic plants. Key points:
- Edible vaccines are produced by inserting DNA fragments from pathogens into plants, causing the plants to produce proteins that trigger an immune response when eaten.
- Tomatoes and bananas have been genetically engineered to produce vaccines in their fruit. Edible vaccines can be cheap to produce, stable without refrigeration, and trigger immunity in the digestive system.
- Challenges include standardizing dosage and ensuring the vaccines are not contaminated or mixed with regular plant material. Future work aims to address these challenges and study whether edible vaccines can indirectly vaccinate infants through breastfeeding mothers.Plant-Derived Vaccines
Plant-Derived VaccinesSusan Egbert
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Researchers are looking into developing plant-derived vaccines as an alternative to traditional needle-based vaccines. Plant-derived vaccines could be taken orally by eating plants like corn or potatoes that contain the vaccine, or in capsule form. This approach could provide more affordable and heat-stable vaccines without the health issues of some traditional subunit vaccines produced in cell cultures. The research is still ongoing but initial results have been promising.EDIBLE VACCINES 
EDIBLE VACCINES Dr K SUDHEER KUMAR KANDIBANDA
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A vaccine is a biological preparation that improves immunity to a particular disease.
In the edible vaccine, Transgenic plants are used as vaccine production systems.
The genes encoding antigens of bacterial and viral pathogens can be expressed in plants in a form in which they retain native immunologic properties.
Recombinant Proteins in Plants :Problems and Prospects
Recombinant Proteins in Plants :Problems and ProspectsSenthil Natesan
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Recombinant proteins in plants have problems and prospects. Dr. Ramanjini Gowda delivered a guest lecture at Tamil Nadu Agricultural University on recombinant proteins in plants. Low expression levels, challenges with post-translational modifications, difficulty conducting animal and human studies, and formulation of vaccines are some limitations of producing recombinant proteins in plants. However, plants allow for cost-effective mass production and some proteins have already been expressed successfully in plants.Edible vaccine
Edible vaccineSuyash Jain
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WHAT IS VACCINE
PROPERTIES OF IDEAL VACCINE
TYPES OF VACCINEs
TRADIONTIONAL VS EDIBLE VACCINES
EDIBLE VACCINES :- INTRO AND DEFINITION
STANDARDS FOR EDIBLE VACCINE
HISTORY OF EDIBLE VACCINE
WHY TO CHOOSE EDIBLE VACCINE?
CRITERIA FOR HOST PLANT
DEVELOPING AN EDIBLE VACCINE
METHOD OF VACCINE PRODUCTION
HOW TO MAKE EDIBLE VACCINE
HOW EDIBLE VACCINE WORK (MECHANISM)
FACTOR AFFECTING EDIBLE VACCINE
PROS OF EDIBLE VACCINE
CONS OF EDIBLE VACCINE
PLANTS USED FOR EDIBLE VACCINE PRODUCTION
PROS AND CONS OF SELECTED HOST PLANT
APPLICATION
FUTURE PROSPECTS
CBR.799 Edible Vaccine and and its effects on human .pptx
CBR.799 Edible Vaccine and and its effects on human .pptxbhanvejain
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The document discusses edible vaccines, which are subunit vaccines produced in transgenic plants. Edible vaccines offer advantages like low cost, thermal stability, and needle-free administration through consumption of plant tissues. Various plants used for edible vaccine production are discussed, including tobacco, potato, banana, and rice. Methods for producing edible vaccines like gene gun and Agrobacterium transformation are also summarized. Potential applications of edible vaccines for diseases like hepatitis B and measles are mentioned. The conclusion states that edible vaccines could provide inexpensive immunization in developing countries through plant-derived vaccines.Edible Vaccines
Edible VaccinesRitu_A
Ìý
1. Edible vaccines offer a cost-effective way to deliver vaccines orally by incorporating genes encoding antigens into plants. This allows for vaccines to be stored and administered more easily compared to traditional vaccines.
2. Edible vaccines stimulate both mucosal and systemic immunity by producing antigens when consumed. Various foods like bananas, potatoes, and tomatoes are being investigated for use as edible vaccines.
3. Edible vaccines overcome many issues with traditional vaccines like cold storage and transportation requirements. However, challenges remain around standardizing dosage and ensuring plant stability of the encoded antigens. Future applications of edible vaccines show promise for diseases like cancer, birth control, and autoimmune disorders.More Related Content
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1) The presentation discusses edible vaccines, which are plant-derived oral vaccines that can help address issues with traditional vaccines like cost, need for medical personnel to administer, and unsafe needle reuse.
2) Experiments showed that mice and human volunteers developed an immune response and antibodies after eating transgenic plants engineered to express the hepatitis B surface antigen protein.
3) Edible vaccines could provide a low-cost, easy to administer alternative to traditional vaccines for developing countries and help prevent diseases in areas where access to medical facilities is limited. However, challenges with dosage consistency and stability need further research.Edible vaccine
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Edible vaccines are genetically engineered foods that contain antigens that can provide active immune responses against infections and inflammation. They are easy to store, transport, and can induce both mucosal and systemic immune responses unlike injection vaccines. Candidate plants for edible vaccines include bananas, potatoes, lettuce, tomatoes, rice, wheat and soybeans. While edible vaccines promise a cost-effective and easy way to administer vaccines, challenges include variable dosage amounts, inconsistency between plants, and difficulty selecting the best candidate plant.Edible vaccines 2
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Edible vaccines use transgenic plants to produce antigens from pathogens that can induce an immune response when consumed. The antigen genes are inserted into plants using genetic engineering techniques. When the plant material is eaten, the antigens are released in the intestines and taken up by immune cells, triggering antibody production and immune memory against the pathogen. Some key advantages of edible vaccines are low cost of production and ease of distribution and administration compared to traditional vaccines. However, there are also safety and environmental risks associated with genetically modified crops that require further research. Overall, edible vaccines show promise as a cost-effective delivery method for immunization.Edible vaccine
Edible vaccineIIM Ahmedabad
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Edible vaccines use plants to produce vaccine proteins that are consumed to stimulate immunity. They could provide a cost-effective way to vaccinate remote populations by protecting vaccine proteins from digestion and triggering an immune response through the gut. However, dosage may vary and they are not suitable for infants. Safety issues around environmental contamination must also be addressed.Edible vaccines
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This document provides information about edible vaccines. It begins by defining an ideal vaccine and then defines vaccines in general. It introduces the concept of edible vaccines, which are genetically engineered foods that express vaccine antigens to provide immunity. The document discusses the mechanisms of action, methods for transforming DNA into plants, candidate plant species, examples, factors affecting efficacy, applications, limitations, regulatory issues, recent discoveries, advantages and disadvantages, and future aspects of edible vaccines.edible vaccine
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Rekha presented on edible vaccines. Edible vaccines involve introducing genes from pathogens into plants to produce antigens. When consumed, these plant-based vaccines stimulate mucosal and systemic immunity. Various pathogens have been expressed in plants, including ETEC, cholera, Norwalk virus, hepatitis B, and measles. Advantages are oral delivery, lower costs, and stability without refrigeration. Challenges include ensuring consistent dosage and developing tolerance. Many organizations in India are researching edible vaccine candidates for diseases like malaria, tuberculosis, dengue, and hepatitis E.Sagar alone edible vaccine
Sagar alone edible vaccinesagar alone
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1. Edible vaccines work by introducing genes into food crops so that they produce vaccine antigens, which then stimulate an immune response when the plant is eaten.
2. Genes can be inserted through techniques like particle bombardment or Agrobacterium transformation, then the plant is grown and eaten to deliver the vaccine.
3. Clinical trials have explored edible vaccines for diseases like cholera, hepatitis B, rabies, and norovirus with some success in animal models.EDIBLE VACCINES
EDIBLE VACCINESP. G. Department of Botany, Berhampur University
Ìý
This document discusses edible vaccines, which are vaccines that can be administered orally by eating plants that have been genetically engineered to produce antigens. Edible vaccines are developed using methods like Agrobacterium transformation or gene gun methods to insert DNA encoding antigens into plants. Candidates for edible vaccines include crops like bananas, potatoes, and tomatoes that are engineered to produce antigens for diseases like hepatitis, malaria, measles, and diabetes. Edible vaccines offer advantages like reduced costs and ability to deliver multiple antigens orally, but also have limitations regarding stability and consistency of dosage.Edible Vaccines
Edible VaccinesSurbhiSharma196
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Edible vaccines are plant-based vaccines that are given orally. They were first tested on humans in 1997 using potatoes to deliver vaccines. Since then, many plant species like tobacco, tomatoes, and potatoes have been genetically engineered to produce vaccines for diseases like hepatitis B, cholera, norovirus, and rabies. Recent research has focused on developing edible vaccines for insects like honeybees and livestock like pigs. Advantages are low-cost production and inducing mucosal immunity through oral administration but challenges include variable dosage and immunotolerance.Ph02 edible vaccines
Ph02 edible vaccinesSrinivas Bhairy
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This document provides an overview of edible vaccines. It discusses how edible vaccines are produced by introducing genes encoding vaccine antigens into edible plants using transformation methods. The document outlines various plant species used for edible vaccines like tomatoes, rice, maize, potatoes, and tobacco. It discusses factors affecting the efficacy of edible vaccines and provides examples of edible vaccine research for diseases like malaria, measles, hepatitis B, norovirus, and Alzheimer's disease. The conclusion states that edible vaccines could improve vaccination programs in developing countries by reducing costs and need for cold storage.plant based vaccine
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This document discusses vaccines and the potential for using plants as bioreactors to produce vaccines. It notes that vaccines provide active immunity against diseases and typically contain weakened or killed forms of pathogens. Vaccination is an effective public health measure. Recently, genetically engineering plants to express antigen proteins from pathogens has emerged as a way to develop subunit vaccines more economically than traditional methods. The document outlines opportunities like safety, immune response, stability, low cost, and challenges like regulatory concerns for plant-based vaccines. It provides examples of plant-made influenza vaccines in development that could allow rapid production in response to pandemics.Plant Based Edible Vaccines
Plant Based Edible VaccinesBir Bahadur Thapa
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1. Plant-based edible vaccines produced in crops like bananas, potatoes, and tomatoes show promise as a cheap and effective way to deliver vaccines orally. Clinical trials have shown plant-based vaccines for diseases like cholera and E. coli infection can generate protective immune responses.
2. However, challenges remain regarding safety, dosage control, and public perception of genetically modified crops. Further research is still needed to optimize plant varieties and production methods before wide-scale use of edible vaccines.
3. While holding potential for improving global public health, particularly in developing areas, plant-based edible vaccines face regulatory hurdles and opposition related to their use of genetic engineering technologies.FOOD AS VACCINE
FOOD AS VACCINE konatham teja kumar reddy
Ìý
Edible vaccines are plant- or animal-based vaccines that are ingested rather than injected. They were first developed in the 1990s as a cheaper alternative that doesn't require cold storage. Some early examples included transgenic potatoes and tomatoes that delivered antigens for E. coli and norovirus when eaten. Edible vaccines have advantages like low cost, easy delivery through eating, and no need for cold storage. However, they also have disadvantages like inconsistent dosage between plants and potential allergic reactions. The document discusses applications for edible malaria and hepatitis B vaccines and limitations like immune tolerance and stability.Edible vaccines
Edible vaccinesmasume jahed
Ìý
This document summarizes a seminar presentation on edible vaccines produced through molecular farming. It discusses isolating genes of interest and expressing them in plants, bacteria, yeast or mammalian cells. The outputs can include vaccines, therapeutics, and industrial products. Advantages of plant-based molecular farming include low production costs, safety, and ability to accurately fold complex proteins. Different types of edible vaccines are described, along with the history and production methods. Clinical trials and applications for treating infectious diseases, autoimmune diseases and cancer are also summarized.Edible vaccines
Edible vaccinesKalalSrilekha
Ìý
Edible vaccines are plant-based vaccines that are administered orally. They activate mucosal immunity and have several advantages over traditional injectable vaccines like lower cost, easier administration and storage, and activation of mucosal immunity. Common foods that have been engineered to produce edible vaccines include potatoes, lettuce, tobacco. Studies in humans and animals have shown that edible vaccines against diseases like diarrhea, hepatitis B, and measles can successfully induce immune responses and antibody production after oral administration.Plant vaccines
Plant vaccinesNikunj tyagi
Ìý
Plant-based vaccines, also known as edible vaccines, are produced through transgenic plants. Key points:
- Edible vaccines are produced by inserting DNA fragments from pathogens into plants, causing the plants to produce proteins that trigger an immune response when eaten.
- Tomatoes and bananas have been genetically engineered to produce vaccines in their fruit. Edible vaccines can be cheap to produce, stable without refrigeration, and trigger immunity in the digestive system.
- Challenges include standardizing dosage and ensuring the vaccines are not contaminated or mixed with regular plant material. Future work aims to address these challenges and study whether edible vaccines can indirectly vaccinate infants through breastfeeding mothers.Plant-Derived Vaccines
Plant-Derived VaccinesSusan Egbert
Ìý
Researchers are looking into developing plant-derived vaccines as an alternative to traditional needle-based vaccines. Plant-derived vaccines could be taken orally by eating plants like corn or potatoes that contain the vaccine, or in capsule form. This approach could provide more affordable and heat-stable vaccines without the health issues of some traditional subunit vaccines produced in cell cultures. The research is still ongoing but initial results have been promising.EDIBLE VACCINES
EDIBLE VACCINES Dr K SUDHEER KUMAR KANDIBANDA
Ìý
A vaccine is a biological preparation that improves immunity to a particular disease.
In the edible vaccine, Transgenic plants are used as vaccine production systems.
The genes encoding antigens of bacterial and viral pathogens can be expressed in plants in a form in which they retain native immunologic properties.
Recombinant Proteins in Plants :Problems and Prospects
Recombinant Proteins in Plants :Problems and ProspectsSenthil Natesan
Ìý
Recombinant proteins in plants have problems and prospects. Dr. Ramanjini Gowda delivered a guest lecture at Tamil Nadu Agricultural University on recombinant proteins in plants. Low expression levels, challenges with post-translational modifications, difficulty conducting animal and human studies, and formulation of vaccines are some limitations of producing recombinant proteins in plants. However, plants allow for cost-effective mass production and some proteins have already been expressed successfully in plants.Edible vaccine
Edible vaccineSuyash Jain
Ìý
WHAT IS VACCINE
PROPERTIES OF IDEAL VACCINE
TYPES OF VACCINEs
TRADIONTIONAL VS EDIBLE VACCINES
EDIBLE VACCINES :- INTRO AND DEFINITION
STANDARDS FOR EDIBLE VACCINE
HISTORY OF EDIBLE VACCINE
WHY TO CHOOSE EDIBLE VACCINE?
CRITERIA FOR HOST PLANT
DEVELOPING AN EDIBLE VACCINE
METHOD OF VACCINE PRODUCTION
HOW TO MAKE EDIBLE VACCINE
HOW EDIBLE VACCINE WORK (MECHANISM)
FACTOR AFFECTING EDIBLE VACCINE
PROS OF EDIBLE VACCINE
CONS OF EDIBLE VACCINE
PLANTS USED FOR EDIBLE VACCINE PRODUCTION
PROS AND CONS OF SELECTED HOST PLANT
APPLICATION
FUTURE PROSPECTS
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The document discusses edible vaccines, which are subunit vaccines produced in transgenic plants. Edible vaccines offer advantages like low cost, thermal stability, and needle-free administration through consumption of plant tissues. Various plants used for edible vaccine production are discussed, including tobacco, potato, banana, and rice. Methods for producing edible vaccines like gene gun and Agrobacterium transformation are also summarized. Potential applications of edible vaccines for diseases like hepatitis B and measles are mentioned. The conclusion states that edible vaccines could provide inexpensive immunization in developing countries through plant-derived vaccines.Edible Vaccines
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1. Edible vaccines offer a cost-effective way to deliver vaccines orally by incorporating genes encoding antigens into plants. This allows for vaccines to be stored and administered more easily compared to traditional vaccines.
2. Edible vaccines stimulate both mucosal and systemic immunity by producing antigens when consumed. Various foods like bananas, potatoes, and tomatoes are being investigated for use as edible vaccines.
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This document discusses edible vaccines, which are vaccines produced in transgenic plants or animals that are meant to be orally administered. It defines edible vaccines and notes their advantages over traditional vaccines like lower cost, easier storage and distribution, and needle-free administration. The document outlines the mechanism by which edible vaccines activate both mucosal and systemic immunity when consumed. It identifies the first researcher to demonstrate an edible vaccine and provides examples of clinical trials of edible vaccines for diseases like ETEC, norovirus, cholera, measles, and hepatitis B that have shown promise in animal and some human studies. Both advantages like lower cost of production and distribution in developing countries as well as disadvantages related to quality control and dosageVaccines
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The document discusses edible vaccines, which involve genetically engineering plants to produce vaccine antigens that can be delivered orally through consumption of plant parts. Some key points:
- Edible vaccines could provide low-cost, easy to administer vaccines that don't require cold storage. Several plant species have been investigated for their ability to produce vaccine antigens.
- Past research has expressed antigens for diseases like hepatitis B, cholera, rabies, and measles in plants, inducing protective immune responses when consumed. Optimization is still needed regarding antigen stability and dosing consistency.
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This document discusses edible vaccines, which involve genetically engineering plants to produce vaccine antigens that can be delivered orally through consumption of plant parts. Some key points:
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- Early research demonstrated that transgenic potatoes, tobacco plants, and other species could produce antigens for diseases like hepatitis B, cholera, rabies, and norovirus when eaten, and stimulated protective immune responses in animal models.
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The document discusses edible vaccines, which involve genetically engineering plants to express vaccine antigens that stimulate immune responses when consumed. It provides examples of research efforts to develop edible vaccines for diseases like hepatitis B, cholera, and malaria by expressing relevant antigens in crops. Significant challenges remain, such as ensuring vaccine antigens maintain integrity during storage, overcoming safety concerns, and determining optimal dosing for oral vaccines.Edible vaccines
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edible vaccines, advantages of edible vaccines, production of edible vaccines, examples of edible vaccines, benefitsEdible vaccine
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Overview of vaccine and vaccination, types of vaccines with examples, vaccine production technique, adverse effects of vaccination, precautions
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- 1. Presentation On Plant Genetic Engineering Practical(BGE3206)
- 2. Submitted By ASH1413061M | ASH1413062M ASH1413064M | ASH1413065M BKH1413071F Submitted To Md. Anwar Hossain |Assistant Professor Razia Sultana | Assistant Professor Asma Talukder | Lecturer
- 3. Vaccine Vaccine is an antigenic substance prepared from the causative agent of a disease or a synthetic substitute, used to provide immunity against one or several disease. Smallpox vaccine, the first successful vaccine was introduced by Edward Jenner in 1796. Edible Vaccine A vaccine in which an antigenic substance is engineered into an edible part of a plant. The concept of edible vaccine was developed by Arntzen in the 1990s.
- 4.  Should not be toxic  Low levels of side effect  Should not contaminate the environment  Should not cause problem in individual  Technique of vaccination should be simple  Should be cheap  Should provide long lasting immunity
- 5. Recombinant Protein(vaccine) Transgenic plant Protection against Rabies glycoprotein Tomato Rabies virus Foot & mouth virus Arabidopsis Foot & mouth virus Herpes virus B surface antigen Tobacco Herpes simplex virus Cholera toxin B subunit Potato Vibrio cholerae Human cytomegalovirus glycoprotein B Tobacco Human cytomegalovirus
- 6. Traditional vaccine Edible vaccine Too expensive to be used on large scale Comparatively less expensive Lack of physical infrastructure makes it impossible to disseminate the vaccine May be easily available Required trained personnel to administer injections Do not require any trained personnel to administer Required elaborate production facilities, purification, sterilization, packaging No purification strategies required Can’t directly stimulate the immune system Vaccine when taken orally, can directly stimulate the immune system
- 10.  Cost effective  Easy to administer  Easy to store  Acceptable to poor developing countries  Active both mucosal & systemic immunity  Heat stable  Do not require cold chain maintenance  No fear of contamination  Delivery of multiple antigens
- 11.  Transgenic contamination can occur.  Antibiotic resistance marker gene can spread from GM food to pathogenic bacteria.  Selection of best plant is difficult.  Difficulty in dose maintenance.  Consistency of dosage from fruit to fruit, plant to plant & generation to generation is not similar.  Stability of vaccine in fruit is not known.
- 12.  The first trial on humans in 1997 (using the heat labile B- toxin from E. coli) is a milestone on the road to creating inexpensive vaccines that might be particularly useful in immunizing people in developing countries, where high cost and logistical issues, such as transportation and the need for certain vaccines to be refrigerated, can thwart effective vaccination programs.  The hope is that edible vaccines could be grown in many of the developing countries where they would actually be used.  Whatever may be the current situation, a day is not far off when we will be able to pluck a fruit from the garden, eat it and be protected from diseases…making needles needless…