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Principles of Breast
Reconstruction
Dr Adewunmi O. Lukman
Division of Plastic and Reconstructive Surgery
16th
February, 2021
2
Outline
 Introduction
 Timing
Immediate
Delayed
Delayed immediate
 Techniques
Non autologous
Autologous
 Complications
 Summary
2/16/2021
3
Introduction
 Surgery for breast cancer is not finished until the reconstruction has
been completed in those patients who choose to have it.
 Mastectomy for breast cancer can lead to negative psychological
effects on the patient and breast reconstruction, whether immediate
or delayed, can provide significant psychosocial benefits
2/16/2021
4
Introduction
 The ultimate goal of breast reconstruction is to produce a breast
that satisfies the patient's wishes and matches the contralateral
breast, also improving the preoperative breast aesthetics if possible
2/16/2021
5
Introduction
 Indications
 Contraindications
Serious comorbidities
Unresectable local chest wall tumor
Rapidly progressive uncontrollable metastatic disease
2/16/2021
6
Timing
 Immediate
 Delayed
 Delayed-immediate
2/16/2021
7
Timing-Immediate
 Immediate- advantages
1. Potential for a single operation and one period of hospitalization
2. Maximum preservation of breast skin
3. Preservation of the inframammary fold
4. Good-quality skin flaps
5. Better cosmetic results for skin-sparing mastectomy
6. Reduced need for balancing surgery to the contralateral breast
7. Lower costs than delayed reconstruction
2/16/2021
8
Timing-Immediate
 Immediate- disadvantages
1. Limited time for decision-making by patient
2. Increased single operating time
3. Difficulties of coordinating two surgical teams when required
4. Potential in individual patients for complications to result in
delay of adjuvant treatment
2/16/2021
9
Timing-Delayed
 Delayed-Advantages
1. Allows unlimited time for decision-making by the patient
2. Avoids any potential delay of adjuvant treatment
3. Avoids detrimental effects of radiotherapy or chemotherapy
on the reconstruction
2/16/2021
10
Timing-Delayed
 Delayed-Disadvantages
1. Requires replacement of a larger amount of breast skin
2. Mastectomy flaps may be thin, scarred, contracted or
irradiated
3. Mastectomy scar may be poorly positioned
4. May result in a less aesthetically pleasing outcome
5. Requires separate episode of hospitalization
6. Increased treatment cost compared with immediate breast
reconstruction
2/16/2021
11
Timing-Delayed-Immediate
 Delayed-immediate breast reconstruction provides some of the
benefits of both immediate and delayed breast reconstruction
 A skin-sparing mastectomy and immediate reconstruction with a
tissue expander is performed
 Once the final pathology is available, patients who do not require
adjuvant radiotherapy proceed to immediate breast reconstruction.
2/16/2021
12
Timing-Delayed-Immediate
 Those who require radiotherapy have their expander fully deflated
prior to radiotherapy to allow optimal delivery of the radiotherapy,
following which the expander is serially re-expanded within a few
weeks of completion of radiotherapy to prevent contraction of the
skin envelope whilst awaiting delayed reconstruction
2/16/2021
13
Techniques
 Non autologous
Breast implants
Tissue expanders
 Autologous
human tissue
 Combined
2/16/2021
14
Techniques-Non-autologous
 Breast reconstruction by tissue expansion involves the serial
expansion of chest-wall tissue to replace permanently the skin lost
following mastectomy by repeated injections of saline into an
inflatable silicone expander placed behind the pectoralis major
muscle
2/16/2021
15
Techniques-Non-autologous
 This may either be followed by replacement with a definitive implant
once expansion is complete, or in the case of a permanent
expandable breast implant that consists of a silicone outer lumen and
an expandable saline inner lumen, only the filling port may need
removal if it is not integrated into the device
2/16/2021
16
Techniques-Non-autologous
 Indications
1. small non-ptotic breasts
2. bilateral reconstruction, or
3. women who are happy to accept mastopexy or augmentation
procedure on the opposite breast
4. minimal scarring
5. unwilling or unfit to undergo autologous tissue reconstruction
2/16/2021
17
Techniques-Non-autologous
 Contraindications
1. Absent pectoralis major muscles (Poland syndrome)
2. Thin chest wall tissues
3. viability of mastectomy skin flap are uncertain
2/16/2021
18
Techniques-Non-autologous
 Timing
Immediate
Delayed
 Implant selection
weight of removed breast vs volume of implant
Disposable sizers
partially empty the expander to the size of the contralateral
breast
2/16/2021
19
Techniques-Non-autologous
 Intra-op (immediate)
skin marking are done,
inframammary fold
mastectomy is done with skin
preservations
sub muscular pocket for implant
placement is prepared
pectoralis major and serratus
anterior muscle
Alternatively, acellular dermal
matrix can be used
2/16/2021
20
Techniques-Non-autologous
 Intra-op (delayed)
similar to immediate
mastectomy flap is raised
and P. major identified
Tissue expansion is placed
sub muscularly
Expansion is commenced
10-14days after wound has
healed, 30-120ml of saline
2/16/2021
21
Techniques-Non-autologous
2/16/2021
22
Techniques-Non-
autologous
 Breast reconstruction
with sub muscular
tissue expander.
Courtesy of Eva M.
Weiler-Mithoff
2/16/2021
23
Techniques-Non-autologous
2/16/2021
24
Techniques-Non-autologous
 Early complications
1. Haematoma
2. infection
3. mastectomy skin flap
necrosis
4. wound dehiscence
 Late complications
1. Implant
rupture/deflation
2. capsular contracture
3. implant malposition/
rotation
4. implant rippling
5. extrusion
6. asymmetry
2/16/2021
25
Techniques- Autologous
 Autologous breast reconstruction allows creation of a breast whose
texture and appearance match more closely that which has been lost
compared with an implant-based reconstruction
 In addition, the aesthetic result of autologous breast reconstruction
tends to improve with time
 While the latissimus dorsi (LD) and transverse rectus abdominis
musculocutaneous (TRAM) flaps remain popular options for breast
reconstruction, there is increasing popularity of the deep inferior
epigastric artery (DIEP) flap due to its reduced abdominal donor-site
morbidity
2/16/2021
26
Techniques- Autologous
 Indications
Large ptotic breasts
Immediate reconstruction when adjuvant radiotherapy is
planned
Delayed reconstruction after adjuvant radiotherapy
Failed previous implant reconstruction
planned aesthetic abdominoplasty
2/16/2021
27
Techniques- Autologous
(Latissimus dorsi (LD) flap reconstruction)
 Muscle flap only
 Musculocutaneous flap
 Extended musculocutaneous flap (with subcutaneous fat)
 Pedicled or free flap
 Indications
previous abdominal surgery rendering abdominal flap unsuitable
2/16/2021
28
Techniques- Autologous
(Latissimus dorsi (LD) flap reconstruction)
 Contraindications
damaged to flap pedicle from previous surgery e.g. thoracotomy,
axillary surgery
congenital absent of LD muscle
 Disadvantages
scar in the back
shoulder stiffness and upper limb impairment
2/16/2021
29
Techniques- Autologous
(Latissimus dorsi (LD) flap reconstruction)
 Pre-op planning
Confirm the presence of LD muscle
skin requirements: 6-9cm width, 20-25cm length
Volume- lean back: 200cm続
average back: 400-700cm続
larger back: > values
2/16/2021
30
Techniques- Autologous
(Latissimus dorsi (LD) flap reconstruction)
2/16/2021
31
Techniques- Autologous
(Latissimus dorsi (LD) flap reconstruction)
2/16/2021
32
Techniques- Autologous
(Latissimus dorsi (LD) flap reconstruction)
 The defect is closed primarily with quilting sutures under, with or
without drain
 Divide the muscle from insertion
 Divide the thoracodorsal nerve to present unwanted and distracting
motion
 Insetting is done with or without implant
2/16/2021
33
Techniques- Autologous
(Latissimus dorsi (LD) flap reconstruction)
 Early
1. Haematoma
2. infection
3. breast skin necrosis
4. partial or complete flap
failure
5. wound breakdown
 Late
1. seroma
2. implant rupture
3. capsular contracture.
2/16/2021
34
Breast reconstruction with lower
abdominal tissue
 The lower abdominal pannus is usually an excellent source of tissue
for autologous breast reconstruction and leaves an acceptable donor
scar as well as serving as a simultaneous aesthetic abdominoplasty
2/16/2021
35
Breast reconstruction with lower
abdominal tissue
 Indications
 Contraindications
Previous ligature of flap pedicle
previous abdominoplasty
previous liposuction (Relative)
2/16/2021
36
Breast reconstruction with lower
abdominal tissue
 Vessels
Deep superior epigastric artery (internal thoracic aa)
Deep inferior epigastric artery (external iliac aa)
Superficial epigastric artery (femoral aa)
2/16/2021
37
Breast reconstruction with lower
abdominal tissue
 Pedicled- superior epigastric aa
Transverse rectus abdominis muscle (TRAM)
 Free
1. Transverse rectus abdominis muscle (TRAM)
2. Deep inferior epigastric perforator (DIEP) flap
3. Superficial inferior epigastric perforator (SIEA) flap
2/16/2021
38
Breast reconstruction with lower
abdominal tissue (TRAM flap)
2/16/2021
39
Breast reconstruction with lower
abdominal tissue (DIEP flap)
2/16/2021
40
Pedicled TRAM
2/16/2021
41
Free TRAM
2/16/2021
42
Techniques- Autologous
 Other options, free flaps
 Gluteal region
Superior gluteal artery perforator (SGAP)
Inferior gluteal artery perforator (IGAP)
Gluteal musculocutaneous flap
 Medial thigh flap
Transverse upper gracilis (TUG)
Transverse musculocutaneous gracilis (TMG)
 Reubens flap (deep circumflex iliac aa)
2/16/2021
43
Techniques- Autologous
 Early
1. Thrombosis of the
arterial or venous
anastomosis
2. haematoma
3. partial or total flap loss
4. fat necrosis
5. wound breakdown
6. infection of prosthetic
mesh if used
 Late complications
1. donor-site bulge
2. hernia
3. reduced abdominal
strength
2/16/2021
44
Finishing touches
 Surgery for the reconstructed breast
size or shape adjustment: liposuction, mastopexy, augmentation
Lipomodelling
 Surgery for the contralateral breast
Mastopexy, reduction, augmentation
 Surgery to the flap donor site
scar revision, repair of hernia, liposuction, lipofilling, Tx of seroma
2/16/2021
45
Nipple-areola reconstruction
(NAC reconstruction)
 Nipple
composite graft
local flap
 Areola
full thickness skin grafting- areola, labium major
Tattooing
2/16/2021
46
Summary
 Breast reconstruction plays a significant role in the woman's physical,
emotional and psychological recovery from breast cancer.
 Even the best reconstruction will not be able to replace the natural
breast that has been lost.
 Surgical options for reconstruction include the use of tissue expanders
or breast implants and the use of autologous tissue.
 The most commonly used surgical techniques are tissue expansion, LD
musculocutaneous flap with or without implant, lower abdominal
tissue and other free tissue transfers
2/16/2021
47
Summary
 Nippleareola reconstruction leads to increased patient satisfaction
with breast reconstruction
 Due to the variable needs of individual patients, the reconstructive
surgeon must be able to provide the full range of reconstructive
options
2/16/2021
48
Thank you
2/16/2021
49
References
 J. Michael Dixon: Breast Surgery, a companion to specialist surgical
practice, 5th
edition
 Charles H. Thorne: Grabb and Smiths Plastic Surgery, 7th
edition
 Charles F. Brunicardi: Schwartzs principles of Surgery, 10th
edition
2/16/2021

More Related Content

Principles of breast reconstruction.pptx

  • 1. Principles of Breast Reconstruction Dr Adewunmi O. Lukman Division of Plastic and Reconstructive Surgery 16th February, 2021
  • 2. 2 Outline Introduction Timing Immediate Delayed Delayed immediate Techniques Non autologous Autologous Complications Summary 2/16/2021
  • 3. 3 Introduction Surgery for breast cancer is not finished until the reconstruction has been completed in those patients who choose to have it. Mastectomy for breast cancer can lead to negative psychological effects on the patient and breast reconstruction, whether immediate or delayed, can provide significant psychosocial benefits 2/16/2021
  • 4. 4 Introduction The ultimate goal of breast reconstruction is to produce a breast that satisfies the patient's wishes and matches the contralateral breast, also improving the preoperative breast aesthetics if possible 2/16/2021
  • 5. 5 Introduction Indications Contraindications Serious comorbidities Unresectable local chest wall tumor Rapidly progressive uncontrollable metastatic disease 2/16/2021
  • 6. 6 Timing Immediate Delayed Delayed-immediate 2/16/2021
  • 7. 7 Timing-Immediate Immediate- advantages 1. Potential for a single operation and one period of hospitalization 2. Maximum preservation of breast skin 3. Preservation of the inframammary fold 4. Good-quality skin flaps 5. Better cosmetic results for skin-sparing mastectomy 6. Reduced need for balancing surgery to the contralateral breast 7. Lower costs than delayed reconstruction 2/16/2021
  • 8. 8 Timing-Immediate Immediate- disadvantages 1. Limited time for decision-making by patient 2. Increased single operating time 3. Difficulties of coordinating two surgical teams when required 4. Potential in individual patients for complications to result in delay of adjuvant treatment 2/16/2021
  • 9. 9 Timing-Delayed Delayed-Advantages 1. Allows unlimited time for decision-making by the patient 2. Avoids any potential delay of adjuvant treatment 3. Avoids detrimental effects of radiotherapy or chemotherapy on the reconstruction 2/16/2021
  • 10. 10 Timing-Delayed Delayed-Disadvantages 1. Requires replacement of a larger amount of breast skin 2. Mastectomy flaps may be thin, scarred, contracted or irradiated 3. Mastectomy scar may be poorly positioned 4. May result in a less aesthetically pleasing outcome 5. Requires separate episode of hospitalization 6. Increased treatment cost compared with immediate breast reconstruction 2/16/2021
  • 11. 11 Timing-Delayed-Immediate Delayed-immediate breast reconstruction provides some of the benefits of both immediate and delayed breast reconstruction A skin-sparing mastectomy and immediate reconstruction with a tissue expander is performed Once the final pathology is available, patients who do not require adjuvant radiotherapy proceed to immediate breast reconstruction. 2/16/2021
  • 12. 12 Timing-Delayed-Immediate Those who require radiotherapy have their expander fully deflated prior to radiotherapy to allow optimal delivery of the radiotherapy, following which the expander is serially re-expanded within a few weeks of completion of radiotherapy to prevent contraction of the skin envelope whilst awaiting delayed reconstruction 2/16/2021
  • 13. 13 Techniques Non autologous Breast implants Tissue expanders Autologous human tissue Combined 2/16/2021
  • 14. 14 Techniques-Non-autologous Breast reconstruction by tissue expansion involves the serial expansion of chest-wall tissue to replace permanently the skin lost following mastectomy by repeated injections of saline into an inflatable silicone expander placed behind the pectoralis major muscle 2/16/2021
  • 15. 15 Techniques-Non-autologous This may either be followed by replacement with a definitive implant once expansion is complete, or in the case of a permanent expandable breast implant that consists of a silicone outer lumen and an expandable saline inner lumen, only the filling port may need removal if it is not integrated into the device 2/16/2021
  • 16. 16 Techniques-Non-autologous Indications 1. small non-ptotic breasts 2. bilateral reconstruction, or 3. women who are happy to accept mastopexy or augmentation procedure on the opposite breast 4. minimal scarring 5. unwilling or unfit to undergo autologous tissue reconstruction 2/16/2021
  • 17. 17 Techniques-Non-autologous Contraindications 1. Absent pectoralis major muscles (Poland syndrome) 2. Thin chest wall tissues 3. viability of mastectomy skin flap are uncertain 2/16/2021
  • 18. 18 Techniques-Non-autologous Timing Immediate Delayed Implant selection weight of removed breast vs volume of implant Disposable sizers partially empty the expander to the size of the contralateral breast 2/16/2021
  • 19. 19 Techniques-Non-autologous Intra-op (immediate) skin marking are done, inframammary fold mastectomy is done with skin preservations sub muscular pocket for implant placement is prepared pectoralis major and serratus anterior muscle Alternatively, acellular dermal matrix can be used 2/16/2021
  • 20. 20 Techniques-Non-autologous Intra-op (delayed) similar to immediate mastectomy flap is raised and P. major identified Tissue expansion is placed sub muscularly Expansion is commenced 10-14days after wound has healed, 30-120ml of saline 2/16/2021
  • 22. 22 Techniques-Non- autologous Breast reconstruction with sub muscular tissue expander. Courtesy of Eva M. Weiler-Mithoff 2/16/2021
  • 24. 24 Techniques-Non-autologous Early complications 1. Haematoma 2. infection 3. mastectomy skin flap necrosis 4. wound dehiscence Late complications 1. Implant rupture/deflation 2. capsular contracture 3. implant malposition/ rotation 4. implant rippling 5. extrusion 6. asymmetry 2/16/2021
  • 25. 25 Techniques- Autologous Autologous breast reconstruction allows creation of a breast whose texture and appearance match more closely that which has been lost compared with an implant-based reconstruction In addition, the aesthetic result of autologous breast reconstruction tends to improve with time While the latissimus dorsi (LD) and transverse rectus abdominis musculocutaneous (TRAM) flaps remain popular options for breast reconstruction, there is increasing popularity of the deep inferior epigastric artery (DIEP) flap due to its reduced abdominal donor-site morbidity 2/16/2021
  • 26. 26 Techniques- Autologous Indications Large ptotic breasts Immediate reconstruction when adjuvant radiotherapy is planned Delayed reconstruction after adjuvant radiotherapy Failed previous implant reconstruction planned aesthetic abdominoplasty 2/16/2021
  • 27. 27 Techniques- Autologous (Latissimus dorsi (LD) flap reconstruction) Muscle flap only Musculocutaneous flap Extended musculocutaneous flap (with subcutaneous fat) Pedicled or free flap Indications previous abdominal surgery rendering abdominal flap unsuitable 2/16/2021
  • 28. 28 Techniques- Autologous (Latissimus dorsi (LD) flap reconstruction) Contraindications damaged to flap pedicle from previous surgery e.g. thoracotomy, axillary surgery congenital absent of LD muscle Disadvantages scar in the back shoulder stiffness and upper limb impairment 2/16/2021
  • 29. 29 Techniques- Autologous (Latissimus dorsi (LD) flap reconstruction) Pre-op planning Confirm the presence of LD muscle skin requirements: 6-9cm width, 20-25cm length Volume- lean back: 200cm続 average back: 400-700cm続 larger back: > values 2/16/2021
  • 30. 30 Techniques- Autologous (Latissimus dorsi (LD) flap reconstruction) 2/16/2021
  • 31. 31 Techniques- Autologous (Latissimus dorsi (LD) flap reconstruction) 2/16/2021
  • 32. 32 Techniques- Autologous (Latissimus dorsi (LD) flap reconstruction) The defect is closed primarily with quilting sutures under, with or without drain Divide the muscle from insertion Divide the thoracodorsal nerve to present unwanted and distracting motion Insetting is done with or without implant 2/16/2021
  • 33. 33 Techniques- Autologous (Latissimus dorsi (LD) flap reconstruction) Early 1. Haematoma 2. infection 3. breast skin necrosis 4. partial or complete flap failure 5. wound breakdown Late 1. seroma 2. implant rupture 3. capsular contracture. 2/16/2021
  • 34. 34 Breast reconstruction with lower abdominal tissue The lower abdominal pannus is usually an excellent source of tissue for autologous breast reconstruction and leaves an acceptable donor scar as well as serving as a simultaneous aesthetic abdominoplasty 2/16/2021
  • 35. 35 Breast reconstruction with lower abdominal tissue Indications Contraindications Previous ligature of flap pedicle previous abdominoplasty previous liposuction (Relative) 2/16/2021
  • 36. 36 Breast reconstruction with lower abdominal tissue Vessels Deep superior epigastric artery (internal thoracic aa) Deep inferior epigastric artery (external iliac aa) Superficial epigastric artery (femoral aa) 2/16/2021
  • 37. 37 Breast reconstruction with lower abdominal tissue Pedicled- superior epigastric aa Transverse rectus abdominis muscle (TRAM) Free 1. Transverse rectus abdominis muscle (TRAM) 2. Deep inferior epigastric perforator (DIEP) flap 3. Superficial inferior epigastric perforator (SIEA) flap 2/16/2021
  • 38. 38 Breast reconstruction with lower abdominal tissue (TRAM flap) 2/16/2021
  • 39. 39 Breast reconstruction with lower abdominal tissue (DIEP flap) 2/16/2021
  • 42. 42 Techniques- Autologous Other options, free flaps Gluteal region Superior gluteal artery perforator (SGAP) Inferior gluteal artery perforator (IGAP) Gluteal musculocutaneous flap Medial thigh flap Transverse upper gracilis (TUG) Transverse musculocutaneous gracilis (TMG) Reubens flap (deep circumflex iliac aa) 2/16/2021
  • 43. 43 Techniques- Autologous Early 1. Thrombosis of the arterial or venous anastomosis 2. haematoma 3. partial or total flap loss 4. fat necrosis 5. wound breakdown 6. infection of prosthetic mesh if used Late complications 1. donor-site bulge 2. hernia 3. reduced abdominal strength 2/16/2021
  • 44. 44 Finishing touches Surgery for the reconstructed breast size or shape adjustment: liposuction, mastopexy, augmentation Lipomodelling Surgery for the contralateral breast Mastopexy, reduction, augmentation Surgery to the flap donor site scar revision, repair of hernia, liposuction, lipofilling, Tx of seroma 2/16/2021
  • 45. 45 Nipple-areola reconstruction (NAC reconstruction) Nipple composite graft local flap Areola full thickness skin grafting- areola, labium major Tattooing 2/16/2021
  • 46. 46 Summary Breast reconstruction plays a significant role in the woman's physical, emotional and psychological recovery from breast cancer. Even the best reconstruction will not be able to replace the natural breast that has been lost. Surgical options for reconstruction include the use of tissue expanders or breast implants and the use of autologous tissue. The most commonly used surgical techniques are tissue expansion, LD musculocutaneous flap with or without implant, lower abdominal tissue and other free tissue transfers 2/16/2021
  • 47. 47 Summary Nippleareola reconstruction leads to increased patient satisfaction with breast reconstruction Due to the variable needs of individual patients, the reconstructive surgeon must be able to provide the full range of reconstructive options 2/16/2021
  • 49. 49 References J. Michael Dixon: Breast Surgery, a companion to specialist surgical practice, 5th edition Charles H. Thorne: Grabb and Smiths Plastic Surgery, 7th edition Charles F. Brunicardi: Schwartzs principles of Surgery, 10th edition 2/16/2021