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Leah Davis gave a senior project speech about organizing a fundraising effort to help a family in need. She researched how nonprofits were affected by the economy and found it was a difficult time. Her project raised funds through donation jars at local businesses, bake sales, and yard sales. She also wrote letters to churches. Some churches donated money or supplies after she spoke about her efforts. A local newspaper wrote an article about her project, bringing more donations. With the funds raised, she was able to pay for activities and meals for the family, as well as household supplies and furniture donated by others. Through this challenge, Leah grew more confident in public speaking and learned she is capable of making a difference.
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The document is a work log for Leah Davis tracking her activities related to fundraising and distributing donations for a product called "Donations and Expenditures from Fundraisers". Over several months, her activities included meeting with facilitators to plan fundraising ideas, contacting families in need, distributing donation jars, organizing bake sales and yard sales, collecting furniture and clothing donations, giving a speech, and using funds raised to pay bills for families or buy gifts for holidays. Her comments focused on best practices for interactions, presentations, and managing donations.
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Policies, procedures, subject selection and QTACBasic principles involved in the traditional systems of medicine, Chapter 7,...
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Basic principles involved in the traditional systems of medicine include:
Ayurveda, Siddha, Unani, and Homeopathy
Method of preparation of Ayurvedic formulations like:
Arista, Asava, Gutika, Taila, Churna, Lehya and Bhasma
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This document describes about structural metabolism relationship and drug designing and toxicity of drugs in " DRUG METABOLISM"
In Drug Metabolism is the process of converting a drug into product or inert substances after or before reaching at the site of action.
Metabolism plays an important role in elimination of drugs and foreign substance from the body.
The metabolism of any drug is generally characterised by two phases of reaction
1.Metabolic transformation ( biotransformation ) and
2.Conjugation
The Principal site of drug metabolism is the liver, but the kidney, lungs, and GIT also are important metabolic sites.
The enzymatic bio transformations of drugs is known as Drug Metabolism. Because many drugs have structures similar to those of endogenous compounds , drugs may get metabolised by specific enzymes for the related natural substrates as well as by non-specific enzymes.
Reaction type of Phase-I:
1.Oxidation
2.Reduction
3.Hydrolysis
Most drugs are metabolised ,atleast to some extent , by both phases of metabolism.
Example: Metabolism of Aspirin
Acetyl Salicylic acid undergoes hydrolysis to salicylic acid ( metabolic transformation ), which is then conjugated with glycine to form Salicyluric acid ( Conjugation ).
In Phase-II the metabolites formed in Phase-II are converted to more polar and water soluble product by attaching polar and ionisable moiety such as
1.Glucuronic acid
2.Glycine
3.Glutamine
4.Glutathione conjugation
5.Acetylation
6.Methylation
7.Sulfate conjugation
8.Nucleoside and Nucleotide formation
9.Amino Acid Conjugation
10.Fatty Acid and Cholesterol Conjugation
Drug design is the process of creating new drugs by using knowledge of a biological target.
Drug design considers metabolism to optimize pharmaco kinects ( ADME: Absorption , Distribution , Metabolism , Excretion )
Cytochrome CYP450 enzyme in Drug Metabolism is vital in drug design to enhance efficacy , reduce toxicity and improve bioavailability.
Cytochrome P450 enzymes (CYPs) are a superfamily of heme -containing proteins found from bacteria to human.
Cytochrome P-450 activity in various organs like Liver,Lung ,Kidney , Intestine,Placenta
Adrenal and Skin and they shows the relative activity with repect to their organs in the process of drug metabolism.
Most important CYP450 enzymes are CYP1A2 , CYP2C9 , CYP2E1
,etc...
Toxic Effects of Drug Metabolism
Toxicity: Accumulation of Excess of medications in the Blood Stream.
Ariens (1948) and Mitchell and Horning (1984) deal with this topic.
Some examples of Metabolism-Linked Toxicity are
1.Acetaminophen (paracetmol)
2.Isoniazid ( TB drug)
3.Chloroform
4.Dapsone
5.Diazepam
6.Salicylate
7.Halothane (Anesthetic)
8.Tamoxifen (Breast Cancer drug )
9.Clozapine(Antipsychotic)
These drugs are differentiates with the TOXIC METABOLITE , TOXICITY OF METABOLITE.
References for this topic also mentioned at the end.TechSoup Introduction to Generative AI and Copilot - 2025.05.22.pdf
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The future of SEO is trending toward a more human-first and user-centric approach, powered by AI intelligence and collaboration. Are you ready?
Watch as we explore which SEO trends to prioritize to achieve sustainable growth and deliver reliable results. Well dive into best practices to adapt your strategy around industry-wide disruptions like SGE, how to navigate the top challenges SEO professionals are facing, and proven tactics for prioritizing quality and building trust.
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- Predictions for SGEs impact, and how to adapt.
- What E-E-A-T really means, and how to implement it holistically (hint: its never been more important).
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Arista, Asava, Gutika, Taila, Churna, Lehya and Bhasma
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This document describes about structural metabolism relationship and drug designing and toxicity of drugs in " DRUG METABOLISM"
In Drug Metabolism is the process of converting a drug into product or inert substances after or before reaching at the site of action.
Metabolism plays an important role in elimination of drugs and foreign substance from the body.
The metabolism of any drug is generally characterised by two phases of reaction
1.Metabolic transformation ( biotransformation ) and
2.Conjugation
The Principal site of drug metabolism is the liver, but the kidney, lungs, and GIT also are important metabolic sites.
The enzymatic bio transformations of drugs is known as Drug Metabolism. Because many drugs have structures similar to those of endogenous compounds , drugs may get metabolised by specific enzymes for the related natural substrates as well as by non-specific enzymes.
Reaction type of Phase-I:
1.Oxidation
2.Reduction
3.Hydrolysis
Most drugs are metabolised ,atleast to some extent , by both phases of metabolism.
Example: Metabolism of Aspirin
Acetyl Salicylic acid undergoes hydrolysis to salicylic acid ( metabolic transformation ), which is then conjugated with glycine to form Salicyluric acid ( Conjugation ).
In Phase-II the metabolites formed in Phase-II are converted to more polar and water soluble product by attaching polar and ionisable moiety such as
1.Glucuronic acid
2.Glycine
3.Glutamine
4.Glutathione conjugation
5.Acetylation
6.Methylation
7.Sulfate conjugation
8.Nucleoside and Nucleotide formation
9.Amino Acid Conjugation
10.Fatty Acid and Cholesterol Conjugation
Drug design is the process of creating new drugs by using knowledge of a biological target.
Drug design considers metabolism to optimize pharmaco kinects ( ADME: Absorption , Distribution , Metabolism , Excretion )
Cytochrome CYP450 enzyme in Drug Metabolism is vital in drug design to enhance efficacy , reduce toxicity and improve bioavailability.
Cytochrome P450 enzymes (CYPs) are a superfamily of heme -containing proteins found from bacteria to human.
Cytochrome P-450 activity in various organs like Liver,Lung ,Kidney , Intestine,Placenta
Adrenal and Skin and they shows the relative activity with repect to their organs in the process of drug metabolism.
Most important CYP450 enzymes are CYP1A2 , CYP2C9 , CYP2E1
,etc...
Toxic Effects of Drug Metabolism
Toxicity: Accumulation of Excess of medications in the Blood Stream.
Ariens (1948) and Mitchell and Horning (1984) deal with this topic.
Some examples of Metabolism-Linked Toxicity are
1.Acetaminophen (paracetmol)
2.Isoniazid ( TB drug)
3.Chloroform
4.Dapsone
5.Diazepam
6.Salicylate
7.Halothane (Anesthetic)
8.Tamoxifen (Breast Cancer drug )
9.Clozapine(Antipsychotic)
These drugs are differentiates with the TOXIC METABOLITE , TOXICITY OF METABOLITE.
References for this topic also mentioned at the end.TechSoup Introduction to Generative AI and Copilot - 2025.05.22.pdf
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In this engaging and insightful two-part webinar series, where we will dive into the essentials of generative AI, address key AI concerns, and demonstrate how nonprofits can benefit from using Microsofts AI assistant, Copilot, to achieve their goals.
This event series to help nonprofits obtain Copilot skills is made possible by generous support from Microsoft.Odoo 18 Point of Sale PWA - Odoo 際際滷s
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Technology
For example, 52% agree that technology and social media have a negative impact on mental health, but when broken out by race, 61% of Whites felt technology had a negative effect, and only 48% of Hispanics thought it did.
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Hispanics may have a built-in defense against the isolation technology breeds, owing to their large, multigenerational households, strong social support systems, and tendency to use social media to stay connected with relatives abroad.
Age and Gender
When asked how individuals rate their mental health, men rate it higher than women by 11 percentage points, and Baby Boomers rank it highest at 83%, saying its good or excellent vs. 57% of Gen Z saying the same.
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Race Affects Attitudes
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How to Prepare For a Successful Job Search for 2024Albert Qian
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The document provides guidance on preparing a job search for 2024. It discusses the state of the job market, focusing on growth in AI and healthcare but also continued layoffs. It recommends figuring out what you want to do by researching interests and skills, then conducting informational interviews. The job search should involve building a personal brand on LinkedIn, actively applying to jobs, tailoring resumes and interviews, maintaining job hunting as a habit, and continuing self-improvement. Once hired, the document advises setting new goals and keeping skills and networking active in case of future opportunities.Social Media Marketing Trends 2024 // The Global Indie Insights
Social Media Marketing Trends 2024 // The Global Indie InsightsKurio // The Social Media Age(ncy)
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A report by thenetworkone and Kurio.
The contributing experts and agencies are (in an alphabetical order): Sylwia Rytel, Social Media Supervisor, 180heartbeats + JUNG v MATT (PL), Sharlene Jenner, Vice President - Director of Engagement Strategy, Abelson Taylor (USA), Alex Casanovas, Digital Director, Atrevia (ES), Dora Beilin, Senior Social Strategist, Barrett Hoffher (USA), Min Seo, Campaign Director, Brand New Agency (KR), Desh辿 M. Gully, Associate Strategist, Day One Agency (USA), Francesca Trevisan, Strategist, Different (IT), Trevor Crossman, CX and Digital Transformation Director; Olivia Hussey, Strategic Planner; Simi Srinarula, Social Media Manager, The Hallway (AUS), James Hebbert, Managing Director, Hylink (CN / UK), Mundy lvarez, Planning Director; Pedro Rojas, Social Media Manager; Pancho Gonz叩lez, CCO, Inbrax (CH), Oana Oprea, Head of Digital Planning, Jam Session Agency (RO), Amy Bottrill, Social Account Director, Launch (UK), Gaby Arriaga, Founder, Leonardo1452 (MX), Shantesh S Row, Creative Director, Liwa (UAE), Rajesh Mehta, Chief Strategy Officer; Dhruv Gaur, Digital Planning Lead; Leonie Mergulhao, Account Supervisor - Social Media & PR, Medulla (IN), Aurelija Plioplyt, Head of Digital & Social, Not Perfect (LI), Daiana Khaidargaliyeva, Account Manager, Osaka Labs (UK / USA), Stefanie Sohnchen, Vice President Digital, PIABO Communications (DE), Elisabeth Winiartati, Managing Consultant, Head of Global Integrated Communications; Lydia Aprina, Account Manager, Integrated Marketing and Communications; Nita Prabowo, Account Manager, Integrated Marketing and Communications; Okhi, Web Developer, PNTR Group (ID), Kei Obusan, Insights Director; Daffi Ranandi, Insights Manager, Radarr (SG), Gautam Reghunath, Co-founder & CEO, Talented (IN), Donagh Humphreys, Head of Social and Digital Innovation, THINKHOUSE (IRE), Sarah Yim, Strategy Director, Zulu Alpha Kilo (CA).Trends In Paid Search: Navigating The Digital Landscape In 2024
Trends In Paid Search: Navigating The Digital Landscape In 2024Search Engine Journal
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The search marketing landscape is evolving rapidly with new technologies, and professionals, like you, rely on innovative paid search strategies to meet changing demands.
Its important that youre ready to implement new strategies in 2024.
Check this out and learn the top trends in paid search advertising that are expected to gain traction, so you can drive higher ROI more efficiently in 2024.
Youll learn:
- The latest trends in AI and automation, and what this means for an evolving paid search ecosystem.
- New developments in privacy and data regulation.
- Emerging ad formats that are expected to make an impact next year.
Watch Sreekant Lanka from iQuanti and Irina Klein from OneMain Financial as they dive into the future of paid search and explore the trends, strategies, and technologies that will shape the search marketing landscape.
If youre looking to assess your paid search strategy and design an industry-aligned plan for 2024, then this webinar is for you.5 Public speaking tips from TED - Visualized summary
5 Public speaking tips from TED - Visualized summarySpeakerHub
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From their humble beginnings in 1984, TED has grown into the worlds most powerful amplifier for speakers and thought-leaders to share their ideas. They have over 2,400 filmed talks (not including the 30,000+ TEDx videos) freely available online, and have hosted over 17,500 events around the world.
With over one billion views in a year, its no wonder that so many speakers are looking to TED for ideas on how to share their message more effectively.
The article 5 Public-Speaking Tips TED Gives Its Speakers, by Carmine Gallo for Forbes, gives speakers five practical ways to connect with their audience, and effectively share their ideas on stage.
Whether you are gearing up to get on a TED stage yourself, or just want to master the skills that so many of their speakers possess, these tips and quotes from Chris Anderson, the TED Talks Curator, will encourage you to make the most impactful impression on your audience.
See the full article and more summaries like this on SpeakerHub here: https://speakerhub.com/blog/5-presentation-tips-ted-gives-its-speakers
See the original article on Forbes here:
http://www.forbes.com/forbes/welcome/?toURL=http://www.forbes.com/sites/carminegallo/2016/05/06/5-public-speaking-tips-ted-gives-its-speakers/&refURL=&referrer=#5c07a8221d9bChatGPT and the Future of Work - Clark Boyd 
ChatGPT and the Future of Work - Clark Boyd Clark Boyd
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Everyone is in agreement that ChatGPT (and other generative AI tools) will shape the future of work. Yet there is little consensus on exactly how, when, and to what extent this technology will change our world.
Businesses that extract maximum value from ChatGPT will use it as a collaborative tool for everything from brainstorming to technical maintenance.
For individuals, now is the time to pinpoint the skills the future professional will need to thrive in the AI age.
Check out this presentation to understand what ChatGPT is, how it will shape the future of work, and how you can prepare to take advantage. Getting into the tech field. what next 
Getting into the tech field. what next Tessa Mero
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The document provides career advice for getting into the tech field, including:
- Doing projects and internships in college to build a portfolio.
- Learning about different roles and technologies through industry research.
- Contributing to open source projects to build experience and network.
- Developing a personal brand through a website and social media presence.
- Networking through events, communities, and finding a mentor.
- Practicing interviews through mock interviews and whiteboarding coding questions.Google's Just Not That Into You: Understanding Core Updates & Search Intent
Google's Just Not That Into You: Understanding Core Updates & Search IntentLily Ray
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1. Core updates from Google periodically change how its algorithms assess and rank websites and pages. This can impact rankings through shifts in user intent, site quality issues being caught up to, world events influencing queries, and overhauls to search like the E-A-T framework.
2. There are many possible user intents beyond just transactional, navigational and informational. Identifying intent shifts is important during core updates. Sites may need to optimize for new intents through different content types and sections.
3. Responding effectively to core updates requires analyzing "before and after" data to understand changes, identifying new intents or page types, and ensuring content matches appropriate intents across video, images, knowledge graphs and more.How to have difficult conversations 
How to have difficult conversations Rajiv Jayarajah, MAppComm, ACC
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Stop putting off having difficult conversations. Seven practical tips to ensure your next difficult conversation go smoothly. Artificial Intelligence, Data and Competition SCHREPEL June 2024 OECD dis...
Artificial Intelligence, Data and Competition SCHREPEL June 2024 OECD dis...OECD Directorate for Financial and Enterprise Affairs
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