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?:-552:11?ADV Contra Deliv Syst 1995; V??            ???? ??????
                     ?462?



???? ?????? ??????? ?. ???? ???? (???? ????? ???? ???? 2891)?



  ???? ???????: ???? ??? ??????? ???? ??????? ?????
    ????? ????? ??? ?????? ????? ??????? ???????? .?


               ??????? ???????? ?????? ??????? :?

                     ?? 35 ????? (????)?

                ?? ?????????? ???????? ????? :?

                                ?????????? 001% .?       ?1.?
                                 ?????? 001 % .?         ?2.?
                                  ?????? 001%.?          ?3.?
               ????? ?? 05 % ??????? + 05 % ???.?        ?4.?
?????? ??????? :?
?- ?? ????? ???? ?????? ??? 5 ???????, ?? ?????? ?????? ??? 7 ??????
?, ???? ??? ??????? ?????? ?????? ?? ??? ???????? ????????? ?????? ????? 21?
                                                           ????? ??????? :?

???????? ?????? ???????? ???? ?????????? ???????? ?? ???? ?????? ????????????         ?1(?
                                                                  ?001% .?
????????? ??????? ????????? ????? ??????????? ?????????? ?? ????? ??????? ?????????   ?2(?
                                                                    ?001% .?
???????? ?????? ???????? ???? ?????????? ????????? ?? ???? ?????? ?? ?????            ?3(?
                                                                    ?001% .?
???????? ?????? ???????? ???? ?????????? ????????? ?? ???? ?????? ????? ?????         ?4(?
                                ?05%???????+05 % ???.001% .?
                        ??? ??? ???????? ??????? ??? ?????? ?? ??.?                   ?5(?

??? ???? ????? ????? ?? ? Estradiol 17 B?? ? Progesteron??????
        ????? ??21 ???? , ?? ???? 6 ???? ??? ??? ??? ??????? .?
?????????? :?


???? ?????? ?? ???? ???? ?????? ?????? ???? ????? ???? ??????????
?001% , ???????? ??? ???? ????? ?? ???????? ???? ????? ???? ?????
???(05% ???????+ 05 % ???) ?? ???? ????? ????? ????? ?????
??????? ???? ????? ???? ??? ??????? ???? ?????? ????? ????? ???
?? Progesterone??????? ????? ????? .??? ???? ???? ????? ???
?????? ??????? ????? ?? ??? ?? ?????????.??? ??? ??? ??? ????????? ???
                                                        ?????? ?????.?




                                                      ?????????? :?



?????? ??? ??????? ??????? ?? 001% ?? ?????? ????? ????? ??????
????? ???????? ?????? ????????? , ? ???? ???? ???????? ?? ?? ??????
                                            ?????????? ??? ?????????.?

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Proof 1

  • 1. ?:-552:11?ADV Contra Deliv Syst 1995; V?? ???? ?????? ?462? ???? ?????? ??????? ?. ???? ???? (???? ????? ???? ???? 2891)? ???? ???????: ???? ??? ??????? ???? ??????? ????? ????? ????? ??? ?????? ????? ??????? ???????? .? ??????? ???????? ?????? ??????? :? ?? 35 ????? (????)? ?? ?????????? ???????? ????? :? ?????????? 001% .? ?1.? ?????? 001 % .? ?2.? ?????? 001%.? ?3.? ????? ?? 05 % ??????? + 05 % ???.? ?4.?
  • 2. ?????? ??????? :? ?- ?? ????? ???? ?????? ??? 5 ???????, ?? ?????? ?????? ??? 7 ?????? ?, ???? ??? ??????? ?????? ?????? ?? ??? ???????? ????????? ?????? ????? 21? ????? ??????? :? ???????? ?????? ???????? ???? ?????????? ???????? ?? ???? ?????? ???????????? ?1(? ?001% .? ????????? ??????? ????????? ????? ??????????? ?????????? ?? ????? ??????? ????????? ?2(? ?001% .? ???????? ?????? ???????? ???? ?????????? ????????? ?? ???? ?????? ?? ????? ?3(? ?001% .? ???????? ?????? ???????? ???? ?????????? ????????? ?? ???? ?????? ????? ????? ?4(? ?05%???????+05 % ???.001% .? ??? ??? ???????? ??????? ??? ?????? ?? ??.? ?5(? ??? ???? ????? ????? ?? ? Estradiol 17 B?? ? Progesteron?????? ????? ??21 ???? , ?? ???? 6 ???? ??? ??? ??? ??????? .?
  • 3. ?????????? :? ???? ?????? ?? ???? ???? ?????? ?????? ???? ????? ???? ?????????? ?001% , ???????? ??? ???? ????? ?? ???????? ???? ????? ???? ????? ???(05% ???????+ 05 % ???) ?? ???? ????? ????? ????? ????? ??????? ???? ????? ???? ??? ??????? ???? ?????? ????? ????? ??? ?? Progesterone??????? ????? ????? .??? ???? ???? ????? ??? ?????? ??????? ????? ?? ??? ?? ?????????.??? ??? ??? ??? ????????? ??? ?????? ?????.? ?????????? :? ?????? ??? ??????? ??????? ?? 001% ?? ?????? ????? ????? ?????? ????? ???????? ?????? ????????? , ? ???? ???? ???????? ?? ?? ?????? ?????????? ??? ?????????.?