This document summarizes a study that developed a mathematical model to optimize the assignment of travelers to quarantine hotels in Hong Kong. The model aims to minimize contracting and assignment costs while controlling risk and misplacement. It considers the number and prices of rooms in designated quarantine hotels, passenger traffic data, and travel times between demand nodes and hotels. The model is formulated as a mixed-integer linear program and solved using CPLEX to generate Pareto frontiers under different weights for cost and risk tolerance. The proposed design is then compared to assigning travelers based on the current hotel locations and capacities.