Regen slideshow
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This document discusses the potential role of regenerative medicine in the next 100 years. It outlines several approaches being researched like in vivo organ regeneration using stem cell transplantation and differentiated induced pluripotent stem cells. Ex vivo organ regeneration techniques are also discussed, including decellularizing and reseeding pig lungs with human cells. The document suggests that within a decade, significant advancements could be made in areas like xenotransplantation and robotic transplantation to further regenerative medicine goals.
Regen slideshow
- 1. The Role of Regenera-ve Medicine in the 100YSS Contribu-on 128, ID 1172 100YSS Conference, Houston TX 2012 Sept 15 Mar-ne RothblaF, mar@Unither.com United Therapeu-cs Corpora-on 100YSS Regenera-ve Medicine mar@Unither.com 2
- 2. Regenera-ve Medicine in Film 100YSS Regenera-ve Medicine mar@Unither.com 3
- 3. Supernovas (eg Crab Nebula) 竪Galac-c Cosmic Rays, With The Ejected Protons Ricoche-ng Like Billiard Balls Against Galaxys Magne-c Field 100YSS Regenera-ve Medicine mar@Unither.com 4
- 4. Gamma Rays Produced when Ubiquitous Galac-c Cosmic Rays Interact with Interstellar Medium Reveals 100YSS Regenera-ve Medicine mar@Unither.com 5
- 5. Organ Transplants Extend Life 100YSS Regenera-ve Medicine mar@Unither.com 6
- 6. 100YSS Regenera-ve Medicine mar@Unither.com 7 In Vivo Organ Regenera-on Via Stem Cell Transplanta-on 1st Genera-on iPS Technology
- 7. 100YSS Regenera-ve Medicine mar@Unither.com 8 In Vivo Organ Regenera-on Via Stem Cell Transplanta-on 2nd Genera-on iPS Technology
- 8. Transplantable Di鍖eren-ated iPS Cells 100YSS Regenera-ve Medicine mar@Unither.com 9
- 9. In Vivo Liver Regenera-on 100YSS Regenera-ve Medicine mar@Unither.com 10
- 10. 100YSS Regenera-ve Medicine mar@Unither.com 11
- 11. Rat Lungs Can Be Kept Breathing in a Fluid-足Air System for a Week 100YSS Regenera-ve Medicine mar@Unither.com 12
- 12. Decellularized Pig Lungs 100YSS Regenera-ve Medicine mar@Unither.com 13
- 13. Ex Vivo Organ Regenera-on for Transplanta-on (Pig Lungs) 100YSS Regenera-ve Medicine mar@Unither.com 14
- 14. Human Peripheral Endothelial Progenitor Cells Can Be Cultured, Manipulated & SEEDED Human Umbilical Vascular Endothelial Cells Used To Date 100YSS Regenera-ve Medicine mar@Unither.com 15
- 15. Timeframe Considera-on ≒ Human Lung Has About 109 Endothelial Cells ≒ Within a Month, Endothelial Progenitor Cells Found in Peripheral Circula-on Can be Cultured to Around 106 ≒ Doubling Time of Around 30 Days ≒ May Require About a Year to Grow Lungs for Transplant Once Decide to Proceed 100YSS Regenera-ve Medicine mar@Unither.com 16
- 16. Xenogeneic Organ Regenera-on 17 100YSS Regenera-ve Medicine mar@Unither.com
- 17. Xenogeneic Pigs on ONeill Habitat 100YSS Regenera-ve Medicine mar@Unither.com 18
- 18. hEPCR hVWF hCD73 pVWFKO hTFPI hTBM hCD39 19 Coagulate GP1b GP2b3q GTKO hMCP HLA-足E hDAF hMIRL Immune SIRP/ CD47 Lec-ns Sialyda-on Selec-ns 100YSS Regenera-ve Medicine mar@Unither.com
- 19. Da Vinci Surgical Robot 100YSS Regenera-ve Medicine mar@Unither.com 20
- 20. Da Vinci Robots Have Now Explanted Livers for Transplanta-on 100YSS Regenera-ve Medicine mar@Unither.com 21
- 21. Robo-c Transplanta-on on 100YSS of Xenograis or Regen Organs Will Be Prac-cal 100YSS Regenera-ve Medicine mar@Unither.com 22
- 22. Just Like Shepards May 1961 Flight Was <.1% to the Moon 23 100YSS Regenera-ve Medicine mar@Unither.com
- 23. We Can Be 1000x Further Than We Are In Under Ten Years! 24 100YSS Regenera-ve Medicine mar@Unither.com