際際滷

際際滷Share a Scribd company logo
Jack Ryan Reifert
Home Address: 2528 Orella St. Unit-B  Santa Barbara, CA 93109  858-922-5923  reifert@lifesci.ucsb.edu
Work Address: Neuroscience Research Institute  BLDG. 571, RM. 6131  Santa Barbara, CA 93106-5060

Education:
Ph.D.   Molecular, Cellular, and Developmental Biology (MCDB) / Neuroscience Research Institute                        2005-2011
        University of California, Santa Barbara (UCSB)

B.S.    Pharmacological Chemistry                                                                                      1996-2000
        University of California, San Diego (UCSD)

Additional Education:
 Technology Management Program at UCSB: Business education courses pertaining to the health care industry.            2009-2011
 UCSD Extension courses: Introduction to Pharmacology, Mechanisms of Disorders I and II, Neuropharmacology            2002-2005


Industrial Research Experience:
Salmedix INC. La Jolla, CA / Research Associate                                                                      2002-2005
        Bendamustine (Treanda), won FDA approval for treatment of Chronic Lymphocytic Leukemia (CLL)
        and Non-Hodgkins Lymphoma (NHL), 3 years after being acquired by Cephalon pharmaceuticals.
  Working with the biology research group, our work directly influenced Bendamustine clinical trails for B-cell NHL
    and provided evidence for a mechanism of action divergent from other chemotherapies. (See publication for reference.)

BD Pharmingen. La Jolla, CA / Quality Control Associate I                                                              2001-2002
 Coordinated team meetings to efficiently approach problem products, resulting in release of multiple reagents
  from backorder and updated data sheets with new information specific to each product.


Academic Research Experience:
Chemical Engineering (UCSB), Santa Barbara, CA / Postdoctoral Fellow (CIRM)                                            2011-Present
 Topic: Using bacterial peptide display for the detection and inhibition of proteases involved in ovarian cancer
         metastasis with an emphasis on targeting cancer stem cells.

Neuroscience Research Institute (UCSB), Santa Barbara, CA / Graduate Research Assistant                          2005-2011
 Topic: Mechanisms of amyloid beta induced neurodegeneration - involvement of microtubule associated protein tau.

Sam and Rose Stein Institute for Research on Aging (UCSD), La Jolla, CA / Research Associate                        1999-2001
 Was an author on two publications for investigating the involvement of wnt / 硫-catenin signaling in the promotion
  of rheumatoid arthritis using primary synoviocytes isolated from patients.


Selected Publications:
Reifert J, Hartung-Cranston D, Feinstein S.C. Tau fragmentation without marked changes in tau phosphorylation precedes
amyloid beta mediated cell death in cultured hippocampal neurons. J Biol Chem. 286(23): 20797-811. Jun. 2011

Leoni LM, Bailey B, Reifert J, Bendall HH, Zeller RW, Corbeil J, Elliott G, Niemeyer CC. Bendamustine (Treanda) displays a
distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents. Clin Cancer Res. 14(1): 309
17. Jan. 2008

Sen M, Reifert J, Lauterbach K, Wolf V, Rubin JS, Corr M, Carson DA. Regulation of fibronectin and metalloproteinase expression
by Wnt signaling in rheumatoid arthritis synoviocytes. Arthritis Rheum. 46(11): 2867-77. Nov. 2002



Selected Research Skills:
Dissection and culture of primary neurons           RNA, DNA, protein isolation                   Site-directed mutagenesis
Glial cell isolation                                Molecular cloning/subcloning                  Flow cytometry
Tissue embedding and sectioning                     PCR, qPCR, primer design                      Live and fixed-cell imaging
Mammalian tissue culture                            HPLC Protein purification                     Peptide display library design
Immunoprecipitation                                 Transformation / Transfection                 Size exclusion chromatography
In-vivo drug delivery (oral gavage, IV)             Western blotting / 2D Westerns                Virus production / infection
Multiple microscopy systems including fluorescent, confocal, and DSU.                             Cytotoxicity assays

More Related Content

What's hot (18)

Unit 4 week 6 slides
Unit 4   week 6 slidesUnit 4   week 6 slides
Unit 4 week 6 slides
Jonah Howard
ENT Presentation
ENT PresentationENT Presentation
ENT Presentation
apollohealing
Hospital Presentation
Hospital Presentation Hospital Presentation
Hospital Presentation
apollohealing
Molecular Biologist Academic CV for Industry or Private Sector Consideration
Molecular Biologist Academic CV for Industry or Private Sector Consideration Molecular Biologist Academic CV for Industry or Private Sector Consideration
Molecular Biologist Academic CV for Industry or Private Sector Consideration
Sirie Godshalk
Resume
ResumeResume
Resume
ShaquannaYoung
Extreme makeover resume
Extreme makeover resumeExtreme makeover resume
Extreme makeover resume
DearbrotherJohn
Journal of Ethnobotany | Applications of DNA barcoding and future directions ...
Journal of Ethnobotany | Applications of DNA barcoding and future directions ...Journal of Ethnobotany | Applications of DNA barcoding and future directions ...
Journal of Ethnobotany | Applications of DNA barcoding and future directions ...
Innspub Net
PhD CV: Biotechnology
PhD CV: BiotechnologyPhD CV: Biotechnology
PhD CV: Biotechnology
Duke University Career Center
SCK.urcposter2
SCK.urcposter2SCK.urcposter2
SCK.urcposter2
Sarah Kremer
Joseph Granger one page resume times new roman
Joseph Granger one page resume times new romanJoseph Granger one page resume times new roman
Joseph Granger one page resume times new roman
Joseph Granger
Genetic Engineering
Genetic EngineeringGenetic Engineering
Genetic Engineering
OMICS Group | International Science Conferences
Candidate 21524 (srg) cell based scientist
Candidate 21524 (srg)   cell based scientistCandidate 21524 (srg)   cell based scientist
Candidate 21524 (srg) cell based scientist
Jonathan Duckworth
La rivoluzione dellintroduzione del modello LQ nella pratica clinica
La rivoluzione dellintroduzione del modello LQ nella pratica clinicaLa rivoluzione dellintroduzione del modello LQ nella pratica clinica
La rivoluzione dellintroduzione del modello LQ nella pratica clinica
Gemelli Advanced Radiation Therapy
Gene therapy
Gene therapyGene therapy
Gene therapy
conquassate
Matthew Brown resume
Matthew Brown resumeMatthew Brown resume
Matthew Brown resume
Matthew Brown
Campbell_Resume_011515
Campbell_Resume_011515Campbell_Resume_011515
Campbell_Resume_011515
James Campbell
Single cell profiling in crop plants
Single cell profiling in crop plantsSingle cell profiling in crop plants
Single cell profiling in crop plants
roshni mohan
American Society for Microbiology NGS 2020 Aine O'Toole
American Society for Microbiology NGS 2020 Aine O'TooleAmerican Society for Microbiology NGS 2020 Aine O'Toole
American Society for Microbiology NGS 2020 Aine O'Toole
ine Niamh O'Toole
Unit 4 week 6 slides
Unit 4   week 6 slidesUnit 4   week 6 slides
Unit 4 week 6 slides
Jonah Howard
Hospital Presentation
Hospital Presentation Hospital Presentation
Hospital Presentation
apollohealing
Molecular Biologist Academic CV for Industry or Private Sector Consideration
Molecular Biologist Academic CV for Industry or Private Sector Consideration Molecular Biologist Academic CV for Industry or Private Sector Consideration
Molecular Biologist Academic CV for Industry or Private Sector Consideration
Sirie Godshalk
Extreme makeover resume
Extreme makeover resumeExtreme makeover resume
Extreme makeover resume
DearbrotherJohn
Journal of Ethnobotany | Applications of DNA barcoding and future directions ...
Journal of Ethnobotany | Applications of DNA barcoding and future directions ...Journal of Ethnobotany | Applications of DNA barcoding and future directions ...
Journal of Ethnobotany | Applications of DNA barcoding and future directions ...
Innspub Net
Joseph Granger one page resume times new roman
Joseph Granger one page resume times new romanJoseph Granger one page resume times new roman
Joseph Granger one page resume times new roman
Joseph Granger
Candidate 21524 (srg) cell based scientist
Candidate 21524 (srg)   cell based scientistCandidate 21524 (srg)   cell based scientist
Candidate 21524 (srg) cell based scientist
Jonathan Duckworth
La rivoluzione dellintroduzione del modello LQ nella pratica clinica
La rivoluzione dellintroduzione del modello LQ nella pratica clinicaLa rivoluzione dellintroduzione del modello LQ nella pratica clinica
La rivoluzione dellintroduzione del modello LQ nella pratica clinica
Gemelli Advanced Radiation Therapy
Matthew Brown resume
Matthew Brown resumeMatthew Brown resume
Matthew Brown resume
Matthew Brown
Campbell_Resume_011515
Campbell_Resume_011515Campbell_Resume_011515
Campbell_Resume_011515
James Campbell
Single cell profiling in crop plants
Single cell profiling in crop plantsSingle cell profiling in crop plants
Single cell profiling in crop plants
roshni mohan
American Society for Microbiology NGS 2020 Aine O'Toole
American Society for Microbiology NGS 2020 Aine O'TooleAmerican Society for Microbiology NGS 2020 Aine O'Toole
American Society for Microbiology NGS 2020 Aine O'Toole
ine Niamh O'Toole

Viewers also liked (8)

ADAR Enzyme's proposal
ADAR Enzyme's proposalADAR Enzyme's proposal
ADAR Enzyme's proposal
maryvi
Poster2006
Poster2006Poster2006
Poster2006
竜僚旅虜 虜竜旅凌 裡虜隆留
隆旅虜凌亮亮留旅亮 虜留旅 竜虜粒凌僚旅亮 (1880 1909),
隆旅虜凌亮亮留旅亮 虜留旅 竜虜粒凌僚旅亮 (1880 1909),隆旅虜凌亮亮留旅亮 虜留旅 竜虜粒凌僚旅亮 (1880 1909),
隆旅虜凌亮亮留旅亮 虜留旅 竜虜粒凌僚旅亮 (1880 1909),
竜僚旅虜 虜竜旅凌 裡虜隆留
Shear stressposter
Shear stressposterShear stressposter
Shear stressposter
竜僚旅虜 虜竜旅凌 裡虜隆留
Glutamate receptor
Glutamate receptorGlutamate receptor
Glutamate receptor
Anagha Patil
Neuroscience Retreat 2009
Neuroscience Retreat 2009Neuroscience Retreat 2009
Neuroscience Retreat 2009
jreifert
Y1S2 Synapse NMJ Neurotransmitters
Y1S2 Synapse NMJ NeurotransmittersY1S2 Synapse NMJ Neurotransmitters
Y1S2 Synapse NMJ Neurotransmitters
vajira54
3) Cell Receptors, Ola Elgaddar
3) Cell Receptors, Ola Elgaddar3) Cell Receptors, Ola Elgaddar
3) Cell Receptors, Ola Elgaddar
Ola Elgaddar

Similar to Reifert Resume (20)

Reifert CV
Reifert CVReifert CV
Reifert CV
jreifert
Reifert CV
Reifert CVReifert CV
Reifert CV
jreifert
Jane Yang_Resume_10-2016
Jane Yang_Resume_10-2016Jane Yang_Resume_10-2016
Jane Yang_Resume_10-2016
Jane Yang, PhD
Jason C Poole Cv Linked In
Jason C Poole Cv Linked InJason C Poole Cv Linked In
Jason C Poole Cv Linked In
rastare1a
Jack Reifert's CV
Jack Reifert's CVJack Reifert's CV
Jack Reifert's CV
jreifert
JenGibbonsResume
JenGibbonsResumeJenGibbonsResume
JenGibbonsResume
Jennifer Gibbons
Dennis Sheeter, Vita 0116
Dennis Sheeter, Vita 0116Dennis Sheeter, Vita 0116
Dennis Sheeter, Vita 0116
Dennis Sheeter
SWARNAVA ROY CV(01-2016)
SWARNAVA ROY CV(01-2016)SWARNAVA ROY CV(01-2016)
SWARNAVA ROY CV(01-2016)
Swarnava Roy
Miller_07-11-16
Miller_07-11-16Miller_07-11-16
Miller_07-11-16
David Miller
ALEXANDER POLINKOVSKY CV 2015
ALEXANDER POLINKOVSKY CV 2015ALEXANDER POLINKOVSKY CV 2015
ALEXANDER POLINKOVSKY CV 2015
Alex Polinkovsky
Bryan Soper - resume
Bryan Soper - resumeBryan Soper - resume
Bryan Soper - resume
Bryan Soper
David C Crosby PhD MSL CV 120814 linkedin
David C Crosby PhD MSL CV 120814 linkedinDavid C Crosby PhD MSL CV 120814 linkedin
David C Crosby PhD MSL CV 120814 linkedin
David C. Crosby, Ph.D.
Bhd Cv9 24 09
Bhd Cv9 24 09Bhd Cv9 24 09
Bhd Cv9 24 09
guest159879
DPB Resume
DPB ResumeDPB Resume
DPB Resume
Deborah Beebe
David C Crosby PhD MSL CV 120214 linkedin
David C Crosby PhD MSL CV 120214 linkedinDavid C Crosby PhD MSL CV 120214 linkedin
David C Crosby PhD MSL CV 120214 linkedin
David C. Crosby, Ph.D.
Hao Liu Resume 2017-02
Hao Liu Resume 2017-02Hao Liu Resume 2017-02
Hao Liu Resume 2017-02
Hao Liu
James Nelson CV 33016
James Nelson CV 33016James Nelson CV 33016
James Nelson CV 33016
James Nelson
Resume partha mitra-2016-october
Resume partha mitra-2016-octoberResume partha mitra-2016-october
Resume partha mitra-2016-october
Partha Mitra
CV Dr S Kumar
CV Dr S KumarCV Dr S Kumar
CV Dr S Kumar
Dr Sandeep Kumar
F MADIAI CV_2016
F MADIAI CV_2016F MADIAI CV_2016
F MADIAI CV_2016
Francesca Madiai, PhD
Reifert CV
Reifert CVReifert CV
Reifert CV
jreifert
Reifert CV
Reifert CVReifert CV
Reifert CV
jreifert
Jane Yang_Resume_10-2016
Jane Yang_Resume_10-2016Jane Yang_Resume_10-2016
Jane Yang_Resume_10-2016
Jane Yang, PhD
Jason C Poole Cv Linked In
Jason C Poole Cv Linked InJason C Poole Cv Linked In
Jason C Poole Cv Linked In
rastare1a
Jack Reifert's CV
Jack Reifert's CVJack Reifert's CV
Jack Reifert's CV
jreifert
Dennis Sheeter, Vita 0116
Dennis Sheeter, Vita 0116Dennis Sheeter, Vita 0116
Dennis Sheeter, Vita 0116
Dennis Sheeter
SWARNAVA ROY CV(01-2016)
SWARNAVA ROY CV(01-2016)SWARNAVA ROY CV(01-2016)
SWARNAVA ROY CV(01-2016)
Swarnava Roy
Miller_07-11-16
Miller_07-11-16Miller_07-11-16
Miller_07-11-16
David Miller
ALEXANDER POLINKOVSKY CV 2015
ALEXANDER POLINKOVSKY CV 2015ALEXANDER POLINKOVSKY CV 2015
ALEXANDER POLINKOVSKY CV 2015
Alex Polinkovsky
Bryan Soper - resume
Bryan Soper - resumeBryan Soper - resume
Bryan Soper - resume
Bryan Soper
David C Crosby PhD MSL CV 120814 linkedin
David C Crosby PhD MSL CV 120814 linkedinDavid C Crosby PhD MSL CV 120814 linkedin
David C Crosby PhD MSL CV 120814 linkedin
David C. Crosby, Ph.D.
Bhd Cv9 24 09
Bhd Cv9 24 09Bhd Cv9 24 09
Bhd Cv9 24 09
guest159879
David C Crosby PhD MSL CV 120214 linkedin
David C Crosby PhD MSL CV 120214 linkedinDavid C Crosby PhD MSL CV 120214 linkedin
David C Crosby PhD MSL CV 120214 linkedin
David C. Crosby, Ph.D.
Hao Liu Resume 2017-02
Hao Liu Resume 2017-02Hao Liu Resume 2017-02
Hao Liu Resume 2017-02
Hao Liu
James Nelson CV 33016
James Nelson CV 33016James Nelson CV 33016
James Nelson CV 33016
James Nelson
Resume partha mitra-2016-october
Resume partha mitra-2016-octoberResume partha mitra-2016-october
Resume partha mitra-2016-october
Partha Mitra

Reifert Resume

  • 1. Jack Ryan Reifert Home Address: 2528 Orella St. Unit-B Santa Barbara, CA 93109 858-922-5923 reifert@lifesci.ucsb.edu Work Address: Neuroscience Research Institute BLDG. 571, RM. 6131 Santa Barbara, CA 93106-5060 Education: Ph.D. Molecular, Cellular, and Developmental Biology (MCDB) / Neuroscience Research Institute 2005-2011 University of California, Santa Barbara (UCSB) B.S. Pharmacological Chemistry 1996-2000 University of California, San Diego (UCSD) Additional Education: Technology Management Program at UCSB: Business education courses pertaining to the health care industry. 2009-2011 UCSD Extension courses: Introduction to Pharmacology, Mechanisms of Disorders I and II, Neuropharmacology 2002-2005 Industrial Research Experience: Salmedix INC. La Jolla, CA / Research Associate 2002-2005 Bendamustine (Treanda), won FDA approval for treatment of Chronic Lymphocytic Leukemia (CLL) and Non-Hodgkins Lymphoma (NHL), 3 years after being acquired by Cephalon pharmaceuticals. Working with the biology research group, our work directly influenced Bendamustine clinical trails for B-cell NHL and provided evidence for a mechanism of action divergent from other chemotherapies. (See publication for reference.) BD Pharmingen. La Jolla, CA / Quality Control Associate I 2001-2002 Coordinated team meetings to efficiently approach problem products, resulting in release of multiple reagents from backorder and updated data sheets with new information specific to each product. Academic Research Experience: Chemical Engineering (UCSB), Santa Barbara, CA / Postdoctoral Fellow (CIRM) 2011-Present Topic: Using bacterial peptide display for the detection and inhibition of proteases involved in ovarian cancer metastasis with an emphasis on targeting cancer stem cells. Neuroscience Research Institute (UCSB), Santa Barbara, CA / Graduate Research Assistant 2005-2011 Topic: Mechanisms of amyloid beta induced neurodegeneration - involvement of microtubule associated protein tau. Sam and Rose Stein Institute for Research on Aging (UCSD), La Jolla, CA / Research Associate 1999-2001 Was an author on two publications for investigating the involvement of wnt / 硫-catenin signaling in the promotion of rheumatoid arthritis using primary synoviocytes isolated from patients. Selected Publications: Reifert J, Hartung-Cranston D, Feinstein S.C. Tau fragmentation without marked changes in tau phosphorylation precedes amyloid beta mediated cell death in cultured hippocampal neurons. J Biol Chem. 286(23): 20797-811. Jun. 2011 Leoni LM, Bailey B, Reifert J, Bendall HH, Zeller RW, Corbeil J, Elliott G, Niemeyer CC. Bendamustine (Treanda) displays a distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents. Clin Cancer Res. 14(1): 309 17. Jan. 2008 Sen M, Reifert J, Lauterbach K, Wolf V, Rubin JS, Corr M, Carson DA. Regulation of fibronectin and metalloproteinase expression by Wnt signaling in rheumatoid arthritis synoviocytes. Arthritis Rheum. 46(11): 2867-77. Nov. 2002 Selected Research Skills: Dissection and culture of primary neurons RNA, DNA, protein isolation Site-directed mutagenesis Glial cell isolation Molecular cloning/subcloning Flow cytometry Tissue embedding and sectioning PCR, qPCR, primer design Live and fixed-cell imaging Mammalian tissue culture HPLC Protein purification Peptide display library design Immunoprecipitation Transformation / Transfection Size exclusion chromatography In-vivo drug delivery (oral gavage, IV) Western blotting / 2D Westerns Virus production / infection Multiple microscopy systems including fluorescent, confocal, and DSU. Cytotoxicity assays