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RobertGracia Small Animal Clinical Nutrition
AVCID# 106395 August2, 2012
Case 1: Bosco Robinett
Assessthe animal Bosco, a 3-year old,intactmale EnglishSpringer spaniel,wasrecentlystruckbya
motor vehicle. He hadbeena healthydogpriorto the accident. Bosco sufferedafracturedrightfemur
that wassuccessfullyrepairedbyone of the associate veterinariansinyourpractice. Post-operative
recoverywas uneventful exceptforbacterial infectionof the suture line. A secondminorsurgical
procedure wasnecessarytodraina small subcutaneousabscessandplace adrain. Boscois receiving
parenteral antibioticsbasedonculture andsensitivitytestresults fromaspecimenobtainedfromthe
infectedsurgical site. There isnoevidence of osteomyelitis.
Your currentphysical examinationisunremarkable exceptforthe infectedsurgical siteandmildfever.
Bosco currentlyweighs53poundswithan ideal BCS (3/5). Bosco is alertbutis confinedtoakennel in
your hospital. He isallowedtogointoa small run fora few minutesseveral timeseachdaytoeliminate.
You anticipate thathe will be hospitalizedforatleastanotherweekoruntil the infection iscompletely
undercontrol.
Assessthe foodandfeedingmethod Priortothe accident,Boscowasfeda grocery branddry dog food
(AttaBoy). Table foodand rawhide chewswere offeredfrequently. Inthe hospital,Boscohasnotbeen
offeredmuchfood because of the multiple surgical procedures. Hisappetite todayappeared
questionable andyouare not sure if he is eatingenoughfoodtomeethisdailyenergyrequirements.
You note inthe medical recordthathisappetite hasbeenpoorwhenhe wasboardedinyourfacilityin
the past.
Atta BoyDog Food Ingredients:Cookedyellow corn,meatandbone meal,cookedwheat,wheatbran,
corn glutenmeal,animal fat(preservedwithmixedtocopherols),brewersrice,digestof poultryby-
productmeal,poultry by-productmeal,canolaoil,fishmeal,tomatomeal,mineralsandvitamins.
Guaranteedanalysis:Crude protein=not lessthan23%; crude fat = not lessthan9%; crude fiber=not
more than 4%; moisture = notmore than 10%; calcium= not lessthan1% 320 kcal ME/cup Nutrition
statement:Animal feedingtestsubstantiatethatAttaBoy Dog Foodprovidescompleteandbalanced
nutritionforall life stages.
GuidingQuestions1.Whatare the keynutritional factorstoconsiderinthispost-surgical patientwith
secondarybacterial infection?2.Calculate Boscoscurrent,estimatedenergyneeds(i.e.illnessenergy
requirement). Please show all work. How are yougoingto getthese caloriesintoBosco(i.e.how will
youget himto consume all of the calories)?3.Basedon the current information,whatfood,food
dosage,andfeedingmethodwouldyourecommendforBosco? How doesthisfoodcompare to the key
nutritional factorsyoulistedinnumber1? What wouldyoudoif he refusestoeat?4. What parameters
will youmonitortodetermine isyouare feedingplanisadequate,insufficient,orexcessive? How
frequentlywillyoumonitorthese inthispatientandforhow long? What are your long-termnutrition-
relatedplans(next2-3months) forBosco(i.e.plansforwhenhe goeshome)? Please be specificand
thorough.
Case 1: Bosco Robinett
1. What are the keynutritional factorstoconsiderinthispost-surgical patientwithsecondarybacterial
infection?The keynutritional factorswouldbe Highdigestibleproteins,Highdigestiblefats,low to
moderate digestiblecarbohydrates,lowfiber,increasedpotassium,highlypalatable,prebiotics,
probiotics,verysoftconsistencyforfeedingease throughtube if necessary.
2. Calculate Boscoscurrent,estimatedenergyneeds(i.e.illnessenergyrequirement). Pleaseshowall
work. How are yougoingto get these caloriesintoBosco(i.e.how will yougethimtoconsume all of the
calories)?53 lbs/2.2 lbs/kg=24.1 kg , 1.0 x RER = 1.0 x [70(24.1 kg).75]=761 kcal per dayinitially
increasingthe multiplyingfactordependingonif weightlosshasoccurred,and/orhealthimprovement
continues.Iwouldfirstbeginby measuringthe propercaloricamountof foodnecessaryforthe entire
day andbreak thatamount upover4 - 6 feedings.Iwouldmeasure the total amountof foodfedfor
each meal before andaftertofirstsee if Bosco isconsumingthe correctamount.If notinterestedin
eatingI wouldtryto entice himintoeatingbyheatingthe food,handfeeding,ortryingto provide an
appetite stimulantsuchasdiazepam,etc.If that doesnotworkthenI wouldplace a feedingtube in
Bosco,such as a E tube or G tube to ensure the correctamountof caloriesisbeingconsumed.
3. Based onthe currentinformation,whatfood,fooddosage,andfeedingmethodwouldyou
recommendforBosco? How doesthisfoodcompare to the keynutritional factorsyoulistedinnumber
1? What wouldyoudoif he refusestoeat?I wouldtryto feedBoscoa recoveryformulasuchas Hills
Science DietA/D.Iwouldfeed4村 cans per day,whichisequal to 763 kcal ,Iwouldadjustamount
accordinglyif weightlosshasoccurred,andas Bosco is becominghealthier. Iwouldbreakupthe
feedingsinto6feedings.The first5feedingswouldbe 他of a can and the 6th feedingwouldbe 遜of a
can. The latteris basedonlittle tono weightlossaswell asnohistoryof anorexiacausinganyGI
compromise.If there hasbeenanorexiathenIwouldadhere tothe followingschedule: 1/3 of the daily
caloricintake forday 1, 2/3 of the dailycaloricintake forday2, and the full dailycaloricintake forday3
and beyond.Thisfoodcontainsthe keynutritional factorsasI listedabove,exceptthatitdoesnot
provide probioticsandprebioticstohelpreplenishthe normal gutflorainthe patientthatiscurrentlyon
antibiotics.If BoscorefusestoeatthenIwouldmostlikelyplace afeedingtube suchasan E or G tube
until Boscois consistentlyeatingonhisownforsome time.
4. What parameterswill youmonitortodetermineisyouare feedingplanisadequate,insufficient,or
excessive? Howfrequentlywill youmonitorthese inthispatientandforhow long? What are your long-
termnutrition-relatedplans(next2-3months) forBosco (i.e.plansforwhenhe goeshome)? Please be
specificandthorough.Iwouldmonitorweighteverydayusingthe same scale andat the same time to
determine weightgainorlossandpreserve consistency.Iwouldalsomonitordailydefecationsto
ensure the dietisbeingtoleratedandthere are nosignsof diarrhea.Iwouldalsoperforma body
conditionscore onBosco every2 to 3 days to see if I notice anysignificantdeviationsfromthe ideal.I
wouldalsorunbloodglucose at leasttwice dailytoensure
that Boscosglucose levelsdonotdropbelow normal levelsbetweenfeedingintervals.Iwouldmonitor
all these levelsuntil Boscoisconsistentlyeatingonhisownorhas leftthe hospital.If Boscoisat home
and still beingfedbytube Iwouldhave toadjustwhatmonitoringIcoulddo accordingto the ownerand
availability.Once BoscoiseatingconsistentlyIwouldremove the tube if itwasnecessaryandstartto
transitionhimovertohisnewdiet.Iwouldrecommendtryingtograduallydecrease the amountof table
foodand rawhidesthatBoscowas receivinginthe pastbecause theyare a source of increasedcalories
and notnecessarilyof anysignificantnutritional benefit.If inthe pastBoscowas at an ideal body
conditionscore,andwashealthywhile beingfedAttaBoyDogfood,thenI see noneedto change that
food.I wouldfeedhimthe recommendedcaloricamountforan intactmale 53 lbs/2.2 lbs/kg=24.1 kg ,
1.8 x RER = 1.8 x [70(24.1 kg).75]=1,371 kcal per day.Thisis equivalentto4 村 to 4 遜 cups of Atta Boy
dog foodperday.I wouldbreakthe meal upintotwoseparate feedingsof 2 村 cups each.I wouldlike to
see Boscoback in twoweekstocheckhisweight andperforma bodyconditionscore.Iwouldadjustdiet
accordinglydependingonmyfindings.Once the infectionhassubsidedandBoscoisoff antibioticsI
wouldlike tostarthimon a course of prebiotics/probiotics(fortiflor,bene bac) tohelprestore normal
gut flora.Recheckradiographstoensure properfracture healing.Iwouldalsorecommendthatif Bosco
isnot goingto be a stud,the ownersmayconsidercastrationat a latertime,since thismayhelpprevent
roamingand decrease the riskof anothermotorvehicle encounter.(The latterisdependentonif the
accidentoccurredoff the propertyetc.) If the ownersdoelecttohave Bosco castratedthenthe amount
of foodbeingfedmustbe recalculatedforadog thatis no longerintactandalso depends onhiscurrent
activitylevel.
Case 2. Heidi Willis
Assessthe PatientHeidi,a7-yearold,spayedfemale,Dobermanpinscher,ispresentedtoyourclinicfor
herannual heartwormtest. She currentlyweighs60pounds. Heidi isan outdoordogwho is keptina
fencedbackyard or chainlinkkennel withinsulateddoghouse. She liveswithhercaregiver,Ms.Willis,
and 2 elderlycats. She iscurrenton all of her vaccinations. Yourphysical examinationrevealsalean
and alertDobermanwitha BCSof 2/5. The medical recordindicatesthatshe weighed69poundsand
had a BCS of 3/5 two yearsearlier.
Blooddrawnfor the heartwormtestrevealsayellow tinge tothe plasma. Beingconcerned,youdraw
more bloodand submititfora CBC andserumbiochemistryprofile. The dogsurinarybladderisbarely
palpable butyoumanage to obtain5 cc of urine viacystocentesisforaUA. On a secondand more
careful look,younotice thathermucousmembranesappearicteric. The onlyabnormalitynotedonthe
CBC resultsisa commentaboutoccasional targetcellsbeingseenonthe microscopicexaminationof the
bloodsmear. Abnormalitiesonthe serumbiochemical profile include albumin=1.9 g/dl (normal 2.5-3.8
g/dl);BUN = 8 mg/dl (normal 9-27 mg/dl);ALT= 301 IU (normal 21-67 IU); SAP= 362 IU (normal 14-72
IU); and total bilirubin=2.5 mg/dl (normal < 0.3 mg/dl). The urinalysisrevealsa3+ bilirubinuriawitha
specificgravityof 1.030 and a urine pH of 7.0. Additional workup:surveyabdominal radiography(small
liver) andliverbiopsy(hepaticdegenerationandnecrosiswithamixedinflammatoryresponse).
of copper/gof tissue). Yoususpectchronicactive
hepatitis.
Assessthe FoodandFeedingMethodHeidi hasbeenfree choice feddry,High-Prodogfood. However,
Ms. WillisindicatedthatHeidisappetite wasabitoffbecause she wasnot refillingHeidisfoodbowl
as often.
High-ProDogFood Ingredientlist:Cookedyellow corn,meatandbone meal,cookedwheat,wheatbran,
corn glutenmeal,animal fat(preservedwithmixedtocopherols),brewersrice,digestof poultry
byproductmeal,poultryby-productmeal,canolaoil,fishmeal,tomatomeal,mineralsandvitamins.
Guaranteedanalysis:27%protein;10% fat;4% fiber;12% moisture Nutritionstatement:Hi-Prois
formulatedtoprovide complete andbalancednutritionformaintenance.
GuidingQuestions1.Giventhisinformation,whatisyourinitial treatmentplan? Please be concise and
thorough.2. What are the keynutritional factors(KNF) andtheirappropriatelevelstoconsiderforthis
patient?3. What food,fooddosage andfeedingmethodwouldyourrecommendforHeidi (show all
work)? How doesthe foodcompare withthe keynutritional factors(i.e.compare eachfactor) youlisted
inquestion2? Whenand howwill youintroduce yourchosenfood?4.What are yourlong-termplans
for Heidi? Whatparameterswill youmonitortodetermine if yourtreatmentisadequate,insufficient,or
excessive? Howfrequentlywill youmonitorthese inthispatientandforhow long?
Case 2: Heidi Willis
1. Giventhisinformation,whatisyourinitial treatmentplan? Please be concise andthorough.If any
signsof dehydrationIwouldbeginwithfluidtherapytoreplace losesandtocorrect any electrolyte
imbalances.IwouldstartHeidi ona course of prednisolone(glucocorticoids) andantibiotics(depending
on culture or can use ampicillin,metronidazole,etc.) for1 2 months.Alsostarton hepatoprotectants
(ursodiol),andpossiblysupplementwithVitaminCandZinc to decrease copperlevels.Bvitaminsand
digestive enzymesupplementationcanalsobe given.Provide supportforanyotherclinical signsthat
developsuchasvomiting,ascites,etc.Provide anew dietwithhighqualityrestrictedproteinandcertain
minerals.Recheckin2weekstodetermine weightgain,anddiettolerance.Recheckbloodlevelswhile
on steroids.Followupradiographsand/orultrasoundtodetermineascitesorprogressionof cirrhosis.
Additional liverbiopsyasneededdue tolongtermglucocorticoidtreatment.
2. What are the keynutritional factors(KNF) andtheirappropriate levelstoconsiderforthispatient?
The keynutritional factorsforthispatientare highqualityandhighlydigestible moderate amountsof
protein,normal amountof highlydigestible fat,normal amountof highlydigestible carbohydrates,
higherlevelsof fermentablefiber,normal toslightlyhigherlevelsof taurine,iron,zinc,potassium,L-
Carnitine,andvitamins,decreasedlevelsof sodiumchloride,andcopper.
3. What food,fooddosage and feedingmethodwouldyourecommendforHeidi (show all work)? How
doesthe foodcompare withthe keynutritional factors(i.e.compare eachfactor) youlistedinquestion
2? Whenand howwill youintroduce yourchosenfood?IwouldfeedHeidi HillsScience DietL/DCanine
HepaticHealth.IwouldfeedHeidi forweight gaintobringherback to an ideal body
conditionscore,butstartingoutat a lowermultipliersince she mighthave beenanorexic.If there has
beenanorexiathenIwouldadhere tothe followingschedule: 1/3of the dailycaloricintake forday1,
2/3 of the dailycaloricintake forday2, and the full dailycaloricintake forday3 and beyond.69 lbs/2.2
lbs/kg=31.4 kg , 1.2 x RER = 1.2 x [70(31.4 kg).75]= 1,113 kcal per day.I wouldfeed2他 cupsto 3 cups
perday, 1 遜 cupstwice dailyequal to1,197 kcal per day.The keynutritional factorsmatchup well
concerningprotein,carbohydrates,fat,fiber,L- Carnitine,copper,iron,zinc,potassium, andsodium, I
couldnot findinformationaboutthe varioustypesof vitamins,andtaurine andthere levels includedin
the diet.I wouldintroduce the foodtoHeidi athome ratherthan the clinicsothat she wouldnotbe
adverse toit.I wouldslowlyswitchherovertothe new foodovera weeklongperiodasfollows:day1=
90% old,10% new;day 2= 75% old,25% new;day3= 60% old,40% new;day 4= 50% old,50% new;day
5= 40% old,60% new;day 6= 25% old,75% new;day7= 10% old,90% new;day8= 100% new diet.
4. What are your long-termplansforHeidi? Whatparameterswillyoumonitortodetermineif your
treatmentisadequate,insufficient,orexcessive? How frequentlywillyoumonitorthese inthispatient
and forhow long?I wouldstartHeidi ona course of prednisolone (glucocorticoids) andantibiotics
(dependingonculture orcan use ampicillin,metronidazole,etc.) for1  2 months.Alsostarton
hepatoprotectants(ursodiol),andpossiblysupplementwithVitaminC,E and Zincto decrease copper
levels.Bvitaminsanddigestiveenzyme supplementationcanalsobe given.Provide supportforany
otherclinical signsthatdevelopsuchasvomiting,ascites,etc.Recheckin2weekstodetermine weight
gain,and diettolerance.Reweighandassessdiet,recheckagainevery2weeksuntil weightlevel is
appropriate thenadjustcaloricintake formaintenance.Recheckbloodlevels(Albumin,AST,ALP,total
Bilirubin,BUN,CBC,WBC,copper,sodium, potassium,etc.) while onsteroidsforlongterm.Followup
radiographs and/orultrasoundina couple of monthstodetermine ascitesorprogressionof cirrhosis.
Additional liverbiopsyasneededdue tolongtermglucocorticoidtreatment.Iwouldmonitorweight,
BCS, bloodlevels,andradiographs.Once Heidiisata good weightshe canbe monitoredforweight
stabilityevery4to6 months,andbloodlevelsatleasttwice yearly,andradiographs/ultrasoundatleast
yearly.

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Robert Gracia Small Animal Clinical Nutrition

  • 1. RobertGracia Small Animal Clinical Nutrition AVCID# 106395 August2, 2012 Case 1: Bosco Robinett Assessthe animal Bosco, a 3-year old,intactmale EnglishSpringer spaniel,wasrecentlystruckbya motor vehicle. He hadbeena healthydogpriorto the accident. Bosco sufferedafracturedrightfemur that wassuccessfullyrepairedbyone of the associate veterinariansinyourpractice. Post-operative recoverywas uneventful exceptforbacterial infectionof the suture line. A secondminorsurgical procedure wasnecessarytodraina small subcutaneousabscessandplace adrain. Boscois receiving parenteral antibioticsbasedonculture andsensitivitytestresults fromaspecimenobtainedfromthe infectedsurgical site. There isnoevidence of osteomyelitis. Your currentphysical examinationisunremarkable exceptforthe infectedsurgical siteandmildfever. Bosco currentlyweighs53poundswithan ideal BCS (3/5). Bosco is alertbutis confinedtoakennel in your hospital. He isallowedtogointoa small run fora few minutesseveral timeseachdaytoeliminate. You anticipate thathe will be hospitalizedforatleastanotherweekoruntil the infection iscompletely undercontrol. Assessthe foodandfeedingmethod Priortothe accident,Boscowasfeda grocery branddry dog food (AttaBoy). Table foodand rawhide chewswere offeredfrequently. Inthe hospital,Boscohasnotbeen offeredmuchfood because of the multiple surgical procedures. Hisappetite todayappeared questionable andyouare not sure if he is eatingenoughfoodtomeethisdailyenergyrequirements. You note inthe medical recordthathisappetite hasbeenpoorwhenhe wasboardedinyourfacilityin the past. Atta BoyDog Food Ingredients:Cookedyellow corn,meatandbone meal,cookedwheat,wheatbran, corn glutenmeal,animal fat(preservedwithmixedtocopherols),brewersrice,digestof poultryby- productmeal,poultry by-productmeal,canolaoil,fishmeal,tomatomeal,mineralsandvitamins. Guaranteedanalysis:Crude protein=not lessthan23%; crude fat = not lessthan9%; crude fiber=not more than 4%; moisture = notmore than 10%; calcium= not lessthan1% 320 kcal ME/cup Nutrition statement:Animal feedingtestsubstantiatethatAttaBoy Dog Foodprovidescompleteandbalanced nutritionforall life stages. GuidingQuestions1.Whatare the keynutritional factorstoconsiderinthispost-surgical patientwith secondarybacterial infection?2.Calculate Boscoscurrent,estimatedenergyneeds(i.e.illnessenergy requirement). Please show all work. How are yougoingto getthese caloriesintoBosco(i.e.how will youget himto consume all of the calories)?3.Basedon the current information,whatfood,food dosage,andfeedingmethodwouldyourecommendforBosco? How doesthisfoodcompare to the key nutritional factorsyoulistedinnumber1? What wouldyoudoif he refusestoeat?4. What parameters will youmonitortodetermine isyouare feedingplanisadequate,insufficient,orexcessive? How frequentlywillyoumonitorthese inthispatientandforhow long? What are your long-termnutrition- relatedplans(next2-3months) forBosco(i.e.plansforwhenhe goeshome)? Please be specificand thorough.
  • 2. Case 1: Bosco Robinett 1. What are the keynutritional factorstoconsiderinthispost-surgical patientwithsecondarybacterial infection?The keynutritional factorswouldbe Highdigestibleproteins,Highdigestiblefats,low to moderate digestiblecarbohydrates,lowfiber,increasedpotassium,highlypalatable,prebiotics, probiotics,verysoftconsistencyforfeedingease throughtube if necessary. 2. Calculate Boscoscurrent,estimatedenergyneeds(i.e.illnessenergyrequirement). Pleaseshowall work. How are yougoingto get these caloriesintoBosco(i.e.how will yougethimtoconsume all of the calories)?53 lbs/2.2 lbs/kg=24.1 kg , 1.0 x RER = 1.0 x [70(24.1 kg).75]=761 kcal per dayinitially increasingthe multiplyingfactordependingonif weightlosshasoccurred,and/orhealthimprovement continues.Iwouldfirstbeginby measuringthe propercaloricamountof foodnecessaryforthe entire day andbreak thatamount upover4 - 6 feedings.Iwouldmeasure the total amountof foodfedfor each meal before andaftertofirstsee if Bosco isconsumingthe correctamount.If notinterestedin eatingI wouldtryto entice himintoeatingbyheatingthe food,handfeeding,ortryingto provide an appetite stimulantsuchasdiazepam,etc.If that doesnotworkthenI wouldplace a feedingtube in Bosco,such as a E tube or G tube to ensure the correctamountof caloriesisbeingconsumed. 3. Based onthe currentinformation,whatfood,fooddosage,andfeedingmethodwouldyou recommendforBosco? How doesthisfoodcompare to the keynutritional factorsyoulistedinnumber 1? What wouldyoudoif he refusestoeat?I wouldtryto feedBoscoa recoveryformulasuchas Hills Science DietA/D.Iwouldfeed4村 cans per day,whichisequal to 763 kcal ,Iwouldadjustamount accordinglyif weightlosshasoccurred,andas Bosco is becominghealthier. Iwouldbreakupthe feedingsinto6feedings.The first5feedingswouldbe 他of a can and the 6th feedingwouldbe 遜of a can. The latteris basedonlittle tono weightlossaswell asnohistoryof anorexiacausinganyGI compromise.If there hasbeenanorexiathenIwouldadhere tothe followingschedule: 1/3 of the daily caloricintake forday 1, 2/3 of the dailycaloricintake forday2, and the full dailycaloricintake forday3 and beyond.Thisfoodcontainsthe keynutritional factorsasI listedabove,exceptthatitdoesnot provide probioticsandprebioticstohelpreplenishthe normal gutflorainthe patientthatiscurrentlyon antibiotics.If BoscorefusestoeatthenIwouldmostlikelyplace afeedingtube suchasan E or G tube until Boscois consistentlyeatingonhisownforsome time. 4. What parameterswill youmonitortodetermineisyouare feedingplanisadequate,insufficient,or excessive? Howfrequentlywill youmonitorthese inthispatientandforhow long? What are your long- termnutrition-relatedplans(next2-3months) forBosco (i.e.plansforwhenhe goeshome)? Please be specificandthorough.Iwouldmonitorweighteverydayusingthe same scale andat the same time to determine weightgainorlossandpreserve consistency.Iwouldalsomonitordailydefecationsto ensure the dietisbeingtoleratedandthere are nosignsof diarrhea.Iwouldalsoperforma body conditionscore onBosco every2 to 3 days to see if I notice anysignificantdeviationsfromthe ideal.I wouldalsorunbloodglucose at leasttwice dailytoensure that Boscosglucose levelsdonotdropbelow normal levelsbetweenfeedingintervals.Iwouldmonitor all these levelsuntil Boscoisconsistentlyeatingonhisownorhas leftthe hospital.If Boscoisat home and still beingfedbytube Iwouldhave toadjustwhatmonitoringIcoulddo accordingto the ownerand availability.Once BoscoiseatingconsistentlyIwouldremove the tube if itwasnecessaryandstartto transitionhimovertohisnewdiet.Iwouldrecommendtryingtograduallydecrease the amountof table foodand rawhidesthatBoscowas receivinginthe pastbecause theyare a source of increasedcalories
  • 3. and notnecessarilyof anysignificantnutritional benefit.If inthe pastBoscowas at an ideal body conditionscore,andwashealthywhile beingfedAttaBoyDogfood,thenI see noneedto change that food.I wouldfeedhimthe recommendedcaloricamountforan intactmale 53 lbs/2.2 lbs/kg=24.1 kg , 1.8 x RER = 1.8 x [70(24.1 kg).75]=1,371 kcal per day.Thisis equivalentto4 村 to 4 遜 cups of Atta Boy dog foodperday.I wouldbreakthe meal upintotwoseparate feedingsof 2 村 cups each.I wouldlike to see Boscoback in twoweekstocheckhisweight andperforma bodyconditionscore.Iwouldadjustdiet accordinglydependingonmyfindings.Once the infectionhassubsidedandBoscoisoff antibioticsI wouldlike tostarthimon a course of prebiotics/probiotics(fortiflor,bene bac) tohelprestore normal gut flora.Recheckradiographstoensure properfracture healing.Iwouldalsorecommendthatif Bosco isnot goingto be a stud,the ownersmayconsidercastrationat a latertime,since thismayhelpprevent roamingand decrease the riskof anothermotorvehicle encounter.(The latterisdependentonif the accidentoccurredoff the propertyetc.) If the ownersdoelecttohave Bosco castratedthenthe amount of foodbeingfedmustbe recalculatedforadog thatis no longerintactandalso depends onhiscurrent activitylevel. Case 2. Heidi Willis Assessthe PatientHeidi,a7-yearold,spayedfemale,Dobermanpinscher,ispresentedtoyourclinicfor herannual heartwormtest. She currentlyweighs60pounds. Heidi isan outdoordogwho is keptina fencedbackyard or chainlinkkennel withinsulateddoghouse. She liveswithhercaregiver,Ms.Willis, and 2 elderlycats. She iscurrenton all of her vaccinations. Yourphysical examinationrevealsalean and alertDobermanwitha BCSof 2/5. The medical recordindicatesthatshe weighed69poundsand had a BCS of 3/5 two yearsearlier. Blooddrawnfor the heartwormtestrevealsayellow tinge tothe plasma. Beingconcerned,youdraw more bloodand submititfora CBC andserumbiochemistryprofile. The dogsurinarybladderisbarely palpable butyoumanage to obtain5 cc of urine viacystocentesisforaUA. On a secondand more careful look,younotice thathermucousmembranesappearicteric. The onlyabnormalitynotedonthe CBC resultsisa commentaboutoccasional targetcellsbeingseenonthe microscopicexaminationof the bloodsmear. Abnormalitiesonthe serumbiochemical profile include albumin=1.9 g/dl (normal 2.5-3.8 g/dl);BUN = 8 mg/dl (normal 9-27 mg/dl);ALT= 301 IU (normal 21-67 IU); SAP= 362 IU (normal 14-72 IU); and total bilirubin=2.5 mg/dl (normal < 0.3 mg/dl). The urinalysisrevealsa3+ bilirubinuriawitha specificgravityof 1.030 and a urine pH of 7.0. Additional workup:surveyabdominal radiography(small liver) andliverbiopsy(hepaticdegenerationandnecrosiswithamixedinflammatoryresponse). of copper/gof tissue). Yoususpectchronicactive hepatitis. Assessthe FoodandFeedingMethodHeidi hasbeenfree choice feddry,High-Prodogfood. However, Ms. WillisindicatedthatHeidisappetite wasabitoffbecause she wasnot refillingHeidisfoodbowl as often. High-ProDogFood Ingredientlist:Cookedyellow corn,meatandbone meal,cookedwheat,wheatbran, corn glutenmeal,animal fat(preservedwithmixedtocopherols),brewersrice,digestof poultry
  • 4. byproductmeal,poultryby-productmeal,canolaoil,fishmeal,tomatomeal,mineralsandvitamins. Guaranteedanalysis:27%protein;10% fat;4% fiber;12% moisture Nutritionstatement:Hi-Prois formulatedtoprovide complete andbalancednutritionformaintenance. GuidingQuestions1.Giventhisinformation,whatisyourinitial treatmentplan? Please be concise and thorough.2. What are the keynutritional factors(KNF) andtheirappropriatelevelstoconsiderforthis patient?3. What food,fooddosage andfeedingmethodwouldyourrecommendforHeidi (show all work)? How doesthe foodcompare withthe keynutritional factors(i.e.compare eachfactor) youlisted inquestion2? Whenand howwill youintroduce yourchosenfood?4.What are yourlong-termplans for Heidi? Whatparameterswill youmonitortodetermine if yourtreatmentisadequate,insufficient,or excessive? Howfrequentlywill youmonitorthese inthispatientandforhow long? Case 2: Heidi Willis 1. Giventhisinformation,whatisyourinitial treatmentplan? Please be concise andthorough.If any signsof dehydrationIwouldbeginwithfluidtherapytoreplace losesandtocorrect any electrolyte imbalances.IwouldstartHeidi ona course of prednisolone(glucocorticoids) andantibiotics(depending on culture or can use ampicillin,metronidazole,etc.) for1 2 months.Alsostarton hepatoprotectants (ursodiol),andpossiblysupplementwithVitaminCandZinc to decrease copperlevels.Bvitaminsand digestive enzymesupplementationcanalsobe given.Provide supportforanyotherclinical signsthat developsuchasvomiting,ascites,etc.Provide anew dietwithhighqualityrestrictedproteinandcertain minerals.Recheckin2weekstodetermine weightgain,anddiettolerance.Recheckbloodlevelswhile on steroids.Followupradiographsand/orultrasoundtodetermineascitesorprogressionof cirrhosis. Additional liverbiopsyasneededdue tolongtermglucocorticoidtreatment. 2. What are the keynutritional factors(KNF) andtheirappropriate levelstoconsiderforthispatient? The keynutritional factorsforthispatientare highqualityandhighlydigestible moderate amountsof protein,normal amountof highlydigestible fat,normal amountof highlydigestible carbohydrates, higherlevelsof fermentablefiber,normal toslightlyhigherlevelsof taurine,iron,zinc,potassium,L- Carnitine,andvitamins,decreasedlevelsof sodiumchloride,andcopper. 3. What food,fooddosage and feedingmethodwouldyourecommendforHeidi (show all work)? How doesthe foodcompare withthe keynutritional factors(i.e.compare eachfactor) youlistedinquestion 2? Whenand howwill youintroduce yourchosenfood?IwouldfeedHeidi HillsScience DietL/DCanine HepaticHealth.IwouldfeedHeidi forweight gaintobringherback to an ideal body conditionscore,butstartingoutat a lowermultipliersince she mighthave beenanorexic.If there has beenanorexiathenIwouldadhere tothe followingschedule: 1/3of the dailycaloricintake forday1, 2/3 of the dailycaloricintake forday2, and the full dailycaloricintake forday3 and beyond.69 lbs/2.2 lbs/kg=31.4 kg , 1.2 x RER = 1.2 x [70(31.4 kg).75]= 1,113 kcal per day.I wouldfeed2他 cupsto 3 cups perday, 1 遜 cupstwice dailyequal to1,197 kcal per day.The keynutritional factorsmatchup well concerningprotein,carbohydrates,fat,fiber,L- Carnitine,copper,iron,zinc,potassium, andsodium, I couldnot findinformationaboutthe varioustypesof vitamins,andtaurine andthere levels includedin the diet.I wouldintroduce the foodtoHeidi athome ratherthan the clinicsothat she wouldnotbe adverse toit.I wouldslowlyswitchherovertothe new foodovera weeklongperiodasfollows:day1=
  • 5. 90% old,10% new;day 2= 75% old,25% new;day3= 60% old,40% new;day 4= 50% old,50% new;day 5= 40% old,60% new;day 6= 25% old,75% new;day7= 10% old,90% new;day8= 100% new diet. 4. What are your long-termplansforHeidi? Whatparameterswillyoumonitortodetermineif your treatmentisadequate,insufficient,orexcessive? How frequentlywillyoumonitorthese inthispatient and forhow long?I wouldstartHeidi ona course of prednisolone (glucocorticoids) andantibiotics (dependingonculture orcan use ampicillin,metronidazole,etc.) for1 2 months.Alsostarton hepatoprotectants(ursodiol),andpossiblysupplementwithVitaminC,E and Zincto decrease copper levels.Bvitaminsanddigestiveenzyme supplementationcanalsobe given.Provide supportforany otherclinical signsthatdevelopsuchasvomiting,ascites,etc.Recheckin2weekstodetermine weight gain,and diettolerance.Reweighandassessdiet,recheckagainevery2weeksuntil weightlevel is appropriate thenadjustcaloricintake formaintenance.Recheckbloodlevels(Albumin,AST,ALP,total Bilirubin,BUN,CBC,WBC,copper,sodium, potassium,etc.) while onsteroidsforlongterm.Followup radiographs and/orultrasoundina couple of monthstodetermine ascitesorprogressionof cirrhosis. Additional liverbiopsyasneededdue tolongtermglucocorticoidtreatment.Iwouldmonitorweight, BCS, bloodlevels,andradiographs.Once Heidiisata good weightshe canbe monitoredforweight stabilityevery4to6 months,andbloodlevelsatleasttwice yearly,andradiographs/ultrasoundatleast yearly.