The document discusses the pathogenesis and treatment of Kushta, a skin disease according to Ayurveda. It states that the aggravation of the three doshas (Vata, Pitta, Kapha) leads to the vitiation of tissues like skin, blood, and muscles. This causes symptoms like discoloration and lesions of the skin. Over time, all tissues in the body are affected. Kushta is considered a multi-factorial disease. Therefore, Panchakarma (five Ayurvedic cleansing techniques) is the primary treatment approach and should be done mildly but repeatedly. Procedures like Vamana (therapeutic vomiting) and Virechana (purgation) may