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CASE PRESENTATION
S.Navya
Pharm-D 4th
year
HT.NO:13117D1007
Vaagdevi College of
Pharmacy,Hanamkonda.
CASE PROFILE
 A male patient of age 28 years was admitted in
general medicine male ward of MGMH with
ip.no:21301 on 13/6/16.
 The patient case profile was explained in soap
format.
SUBJECTIVE FINDINGS:
 Severe pain in both upper and
lower limbs since four days
 Pain in both knee joints since
four days.
 Fever of low grade associated with chills and
rigours since four days.
 Bone pain(osteolgia) since five days.
PAST MEDICAL AND MEDICATION
HISTORY:
 Patient is a known case of sickle cell
anemia since two years.
 NO PAST SOCIAL AND
FAMILY HISTORY WAS
FOUND.
OBJECTIVE FINDINGS
COMPLETE BLOOD PICTURE:17/6
Haemoglobin:7.3gm%
Total RBC:3.2million cells/mm
Total WBC :12,3000cells/cmm
Neutrophils:76% Eosinophils:9%
Lymphocytes:12% monocytes:3%
Pcv:23%, mcv:71%,mch:21pg,mchc:30gm/dl
impression:microcytic hypochromic eosinophilia.
 16/6 LIVER FUNCTION TESTS:
Total bilirubin:9.65mg/dl
Direct bilirubin:5.46mg/dl
SGOT:69.4U/L Alkaline phosphate:160U/L
SGPT:47.1U/L
15/6 SERUM CALCIUM:5.8mg/dl
16/6 Ultrasound of abdomen:
impression:mild hepatosplenomegaly
13/6 BLOOD UREA:45mg%
 PHYSICAL EXAMINATION:
 On examination patient was
conscious and coherent.
 Generalized weakness.
Pallor+
Icterus+
PROVISIONAL DIAGNOSIS:
 Based on chief complaints,
past medical history the patient was diagnosed
with
ABOUT DISEASE;Sickle cell
anemia is a hereditary disease in
which a mutated form of haemoglobin
Distorts the red blood cells into a
cresent shape at low oxygen levels.
SICKLE CELL ANEMIA
 Etiology:genetic inheritence called
autosomal recessive inheritence;a variant of
sickle cell anemia have HbS.HbS has valine
substituent for glutamic acid as the sixth
amino acid in the beta polypeptide compared
with normal hemoglobin.
 Symptoms:Chest pain,pale skin,swelling in
hands and feet,severe pain of joints and
bones,severe infections etc.
Assessment of standard treatment
PLAN
s.n
o
Drugs Dose
ROA
Freq Category
1. IVF 3 pint NS,1 pint RL Electrolyte replinesher
2. Inj.Ceftriaxone 1amp/IM BD 3rd
gen cephalosporin
3. Inj.Diclofenac 1 amp/IM BD analgesic
4. Tab.Hydroxyurea 200mg/PO BD Antimetabolite
5. Tab.Pantoprazole 40mg/PO OD Proton pump inhibitor
6. Tab.Paracetamol 500mg/PO TID Antipyretic
7. Tab.Calcium 500mg/PO OD Calcium supplement
8. Tab.Ursodeoxycholic acid 300mg/PO OD Liver protective
9. Inj.Ketorolac 1amp/IM BD NSAID
Lifestyle modifications
 Take folic acid supplements daily, and
choose a healthy diet.
 Drink plenty of water.
 Avoid temperature extremes. Exposure to
extreme heat or cold can increase your risk of a
sickle cell crisis.
 Exercise regularly, but don't overdo it.
SICKLE CELL1(1)
SICKLE CELL1(1)

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SICKLE CELL1(1)

  • 2. CASE PROFILE A male patient of age 28 years was admitted in general medicine male ward of MGMH with ip.no:21301 on 13/6/16. The patient case profile was explained in soap format. SUBJECTIVE FINDINGS: Severe pain in both upper and lower limbs since four days Pain in both knee joints since four days.
  • 3. Fever of low grade associated with chills and rigours since four days. Bone pain(osteolgia) since five days. PAST MEDICAL AND MEDICATION HISTORY: Patient is a known case of sickle cell anemia since two years. NO PAST SOCIAL AND FAMILY HISTORY WAS FOUND.
  • 4. OBJECTIVE FINDINGS COMPLETE BLOOD PICTURE:17/6 Haemoglobin:7.3gm% Total RBC:3.2million cells/mm Total WBC :12,3000cells/cmm Neutrophils:76% Eosinophils:9% Lymphocytes:12% monocytes:3% Pcv:23%, mcv:71%,mch:21pg,mchc:30gm/dl impression:microcytic hypochromic eosinophilia.
  • 5. 16/6 LIVER FUNCTION TESTS: Total bilirubin:9.65mg/dl Direct bilirubin:5.46mg/dl SGOT:69.4U/L Alkaline phosphate:160U/L SGPT:47.1U/L 15/6 SERUM CALCIUM:5.8mg/dl 16/6 Ultrasound of abdomen: impression:mild hepatosplenomegaly 13/6 BLOOD UREA:45mg%
  • 6. PHYSICAL EXAMINATION: On examination patient was conscious and coherent. Generalized weakness. Pallor+ Icterus+
  • 7. PROVISIONAL DIAGNOSIS: Based on chief complaints, past medical history the patient was diagnosed with ABOUT DISEASE;Sickle cell anemia is a hereditary disease in which a mutated form of haemoglobin Distorts the red blood cells into a cresent shape at low oxygen levels. SICKLE CELL ANEMIA
  • 8. Etiology:genetic inheritence called autosomal recessive inheritence;a variant of sickle cell anemia have HbS.HbS has valine substituent for glutamic acid as the sixth amino acid in the beta polypeptide compared with normal hemoglobin. Symptoms:Chest pain,pale skin,swelling in hands and feet,severe pain of joints and bones,severe infections etc.
  • 10. PLAN s.n o Drugs Dose ROA Freq Category 1. IVF 3 pint NS,1 pint RL Electrolyte replinesher 2. Inj.Ceftriaxone 1amp/IM BD 3rd gen cephalosporin 3. Inj.Diclofenac 1 amp/IM BD analgesic 4. Tab.Hydroxyurea 200mg/PO BD Antimetabolite 5. Tab.Pantoprazole 40mg/PO OD Proton pump inhibitor 6. Tab.Paracetamol 500mg/PO TID Antipyretic 7. Tab.Calcium 500mg/PO OD Calcium supplement 8. Tab.Ursodeoxycholic acid 300mg/PO OD Liver protective 9. Inj.Ketorolac 1amp/IM BD NSAID
  • 11. Lifestyle modifications Take folic acid supplements daily, and choose a healthy diet. Drink plenty of water. Avoid temperature extremes. Exposure to extreme heat or cold can increase your risk of a sickle cell crisis. Exercise regularly, but don't overdo it.