際際滷

際際滷Share a Scribd company logo
Size reduction
1.
 Advantages :-
 Content Uniformity
 Uniform Flow
 Effective Drying
 Increase Surface Area/Viscosity
 Uniform Mixing and Drying
 Improve Rate Of Adsorption
 Improve Dissolution Rate
 Disadvantages :-
 Change In Colour
 Loss Of Aromatic Principle
 Drug Degradation
 Problem Of Preservation
1.




i.
ii.
iii.
iv.



i.
ii.

i.
ii.
iii.
iv.
v.
Rittingers law
Kicks law
Bonds law
Used to predict the energy
requirements for size reduction
 WORKING :-













i.
ii.
iii.
iv.
v.
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Size reduction