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The document describes an experiment where disulfide bonds were engineered into a1-antitrypsin (a1-AT) to lock the movement of helix F (hF) and the connecting loop (thFs3A) during protease inhibition. Disulfide bonds were introduced between thFs3A and strands 3A or 5A of the beta-sheet. The disulfide between thFs3A and strand 5A, but not 3A, eliminated inhibitory activity, suggesting displacement from strand 5A is required for inhibition. The disulfide between thFs3A and strand 3A slowed polymerization without affecting inhibition. This provides direct evidence that hF/thFs3A displacement from strand 5PibPET_iTRAQ_JAD2016
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This document summarizes a study that used proteomics to identify serum biomarkers for Alzheimer's disease (AD) and mild cognitive impairment (MCI) by analyzing serum samples from patients selected based on their PiB-PET imaging scores. The researchers used isobaric tagging and liquid chromatography-tandem mass spectrometry to perform proteome profiling on serum from control, MCI, and AD patients. They identified 79 and 72 differentially expressed proteins in MCI and AD serum, respectively, compared to controls. Integrated analysis with brain tissue data identified three biomarker candidates related to proteolysis: PCSK9, F13A1, and DCD. Validation in independent serum samples confirmed elevated levels of these candidates in MCIJaeggi2010
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1) The study explores the relationship between performance on n-back tasks (working memory tasks) and matrix reasoning tasks (a measure of fluid intelligence).
2) In a first study, they found that dual and single n-back task performance were equally correlated with matrix reasoning tasks, but less correlated with a working memory task.
3) Based on these results, a second study trained participants for 4 weeks on either a single or dual n-back task and tested transfer effects on working memory and fluid intelligence relative to a control group. Both training groups improved more than controls on fluid intelligence, replicating prior results showing n-back training improves fluid intelligence.Jaeggi2010 title
Jaeggi2010 titleMonica Ferguson
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1) The study explores the relationship between performance on n-back tasks (working memory tasks) and matrix reasoning tasks (a measure of fluid intelligence).
2) In a previous study, the authors found that training on a dual n-back task improved performance on matrix reasoning tasks.
3) The current study aims to determine the underlying mechanisms of this transfer effect and evaluate whether training on a single n-back task also improves matrix reasoning.Jaeggi2010
Jaeggi2010Monica Ferguson
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1) The study explores the relationship between performance on n-back tasks (working memory tasks) and matrix reasoning tasks (a measure of fluid intelligence).
2) In a first study, they found that dual and single n-back task performance were equally correlated with matrix reasoning tasks, but less correlated with a working memory task.
3) Based on these results, a second study trained participants for 4 weeks on either a single or dual n-back task and tested transfer effects on working memory and fluid intelligence relative to a control group. Both training groups improved more than controls on fluid intelligence, replicating prior results showing n-back training improves fluid intelligence.title3
title3Monica Ferguson
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This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.title2
title2Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations.title1
title1Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.title1
title1Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.title1
title1Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.title3
title3Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations.title1
title1Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.More Related Content
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El documento describe las diferentes inteligencias m炭ltiples que se promueven en la compa単鱈a H&R Distribuciones, incluyendo la inteligencia ling端鱈stica a trav辿s de capacitaci坦n continua, la inteligencia l坦gico-matem叩tica para brindar un excelente servicio, y la inteligencia interpersonal mediante el fomento de la autonom鱈a, solidaridad y trabajo en equipo.TracyKnottNew
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Tracy Knott has over 25 years of experience in bookkeeping, accounting, and financial management roles. She currently works as a consultant and senior bookkeeper for Blu Logistics, where her duties include recreating cashbooks and sales records from 2014 to present in Pastel software. Previously, she held various accounting roles such as accountant assistant, bookkeeper, and debtors controller for companies like Lochhead, White & Womersley, Digicore, EH Accountancy, and Mustek Electronics. She has extensive experience with financial software like Pastel, SAP, and Excel. Tracy has a strong educational background in accounting and business subjects and aims to be a reliable, hardworking team player.Oechsle pamelaAntonela15899
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El documento presenta los objetivos de una empresa de muebles y accesorios para oficina, que incluyen consolidarse como l鱈deres en el mercado, integrar un equipo capaz de brindar buena atenci坦n al cliente, expandirse internacionalmente en 2012, y proveer dise単os de alta calidad de manera sostenible. Tambi辿n define los conceptos de servicio y calidad de servicio, y enumera los derechos b叩sicos de los clientes y demandas como la comunicaci坦n efectiva y atenci坦n cordial.La Evoluci坦n De Los Sistemas Operativosdebanhy2305
油
Este documento resume la evoluci坦n de los principales sistemas operativos desde 1985 hasta 2016. Comenz坦 con el lanzamiento de Windows 1.0 en 1985 y continu坦 con mejoras en Windows, MacOS y el desarrollo de Linux a lo largo de los a単os. Algunos hitos clave incluyen el 辿xito comercial de Windows 3.0 en 1990, el lanzamiento de Linux en 1991, Windows 95 en 1995 y versiones posteriores de cada sistema operativo que agregaron nuevas caracter鱈sticas y funcionalidad.Classificaci坦 colpbol abrilceipsantmiquellliria
油
El resumen clasifica los equipos de f炭tbol de un mes por puntos, partidos jugados, ganados, perdidos y empatados, as鱈 como goles a favor y en contra. Los Ninjas lideran la tabla con 21 puntos de 7 partidos jugados, ganando todos sus partidos con 32 goles a favor y solo 1 en contra. Los M叩s Flipantes ocupan el segundo lugar con 15 puntos de 5 victorias. El calendario incluye partidos aplazados para mayo y un recordatorio de que la clasificaci坦n tambi辿n est叩 en el blog de Sant Miquel.Performics ces recap_deck
Performics ces recap_deckPerformics
油
The CES 2016 conference showed advances in technologies like drones, smart home appliances, and TV specs. Major tech companies like Google, Amazon, Apple, and Samsung announced strategic partnerships and investments signaling their visions for the future. Key areas seen as transforming communication, commerce, and industries over the next decade include the Internet of Things, smart homes, virtual reality, self-driving cars, and meaningful wearables. The conference also highlighted efforts to humanize technological interactions through more natural and anticipatory interfaces.ProteinSci2007
ProteinSci2007Je-Hyun Baek
油
The document describes an experiment where disulfide bonds were engineered into a1-antitrypsin (a1-AT) to lock the movement of helix F (hF) and the connecting loop (thFs3A) during protease inhibition. Disulfide bonds were introduced between thFs3A and strands 3A or 5A of the beta-sheet. The disulfide between thFs3A and strand 5A, but not 3A, eliminated inhibitory activity, suggesting displacement from strand 5A is required for inhibition. The disulfide between thFs3A and strand 3A slowed polymerization without affecting inhibition. This provides direct evidence that hF/thFs3A displacement from strand 5PibPET_iTRAQ_JAD2016
PibPET_iTRAQ_JAD2016Je-Hyun Baek
油
This document summarizes a study that used proteomics to identify serum biomarkers for Alzheimer's disease (AD) and mild cognitive impairment (MCI) by analyzing serum samples from patients selected based on their PiB-PET imaging scores. The researchers used isobaric tagging and liquid chromatography-tandem mass spectrometry to perform proteome profiling on serum from control, MCI, and AD patients. They identified 79 and 72 differentially expressed proteins in MCI and AD serum, respectively, compared to controls. Integrated analysis with brain tissue data identified three biomarker candidates related to proteolysis: PCSK9, F13A1, and DCD. Validation in independent serum samples confirmed elevated levels of these candidates in MCIMore from Monica Ferguson (20)
Jaeggi2010
Jaeggi2010Monica Ferguson
油
1) The study explores the relationship between performance on n-back tasks (working memory tasks) and matrix reasoning tasks (a measure of fluid intelligence).
2) In a first study, they found that dual and single n-back task performance were equally correlated with matrix reasoning tasks, but less correlated with a working memory task.
3) Based on these results, a second study trained participants for 4 weeks on either a single or dual n-back task and tested transfer effects on working memory and fluid intelligence relative to a control group. Both training groups improved more than controls on fluid intelligence, replicating prior results showing n-back training improves fluid intelligence.Jaeggi2010 title
Jaeggi2010 titleMonica Ferguson
油
1) The study explores the relationship between performance on n-back tasks (working memory tasks) and matrix reasoning tasks (a measure of fluid intelligence).
2) In a previous study, the authors found that training on a dual n-back task improved performance on matrix reasoning tasks.
3) The current study aims to determine the underlying mechanisms of this transfer effect and evaluate whether training on a single n-back task also improves matrix reasoning.Jaeggi2010
Jaeggi2010Monica Ferguson
油
1) The study explores the relationship between performance on n-back tasks (working memory tasks) and matrix reasoning tasks (a measure of fluid intelligence).
2) In a first study, they found that dual and single n-back task performance were equally correlated with matrix reasoning tasks, but less correlated with a working memory task.
3) Based on these results, a second study trained participants for 4 weeks on either a single or dual n-back task and tested transfer effects on working memory and fluid intelligence relative to a control group. Both training groups improved more than controls on fluid intelligence, replicating prior results showing n-back training improves fluid intelligence.title3
title3Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.title2
title2Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations.title1
title1Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.title1
title1Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.title1
title1Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.title3
title3Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations.title1
title1Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.title1
title1Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.title2
title2Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.title1
title1Monica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.際際滷shareadsf
際際滷shareadsfMonica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.際際滷share
際際滷shareMonica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.際際滷share
際際滷shareMonica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations.際際滷share
際際滷shareMonica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.際際滷share
際際滷shareMonica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.際際滷share
際際滷shareMonica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.際際滷share
際際滷shareMonica Ferguson
油
This document contains a list of 5 entries from a CSV file stored at c:\csv\slideshare.csv, with each entry having a title, description, and tags field. The CSV file contains metadata for multiple presentations stored on 際際滷Share.