1. Thomas Hunt Morgan conducted experiments with fruit flies to demonstrate that genes are located on chromosomes.
2. He found that certain traits like eye color in fruit flies were sex-linked, meaning they were located on the X chromosome and exhibited different inheritance patterns between males and females.
3. His work provided early evidence that chromosomes are the structures that carry genetic information from one generation to the next.
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1. 23
22
1
XX XY
X
Y Thomas
Hunt Morgan
4
3 1 XY
XX
F1
F2 2 1 1 2
2
+
F1 =
F1 +
F2 =
X Y + X X
Gamete X Y + X (2x1=2)
F1 X X ( , X Y (
F1
2. X Y + X X
Gamete X Y + X , X (2x2=4)
F2 X X , X X , X Y , X Y
F2 X X ( , X X ( ,
X Y( , X Y(
X X Y
--
sex-
linked gene X X-linked gene
100
G-6-PD
XC Y XC XC
- XC Xc
Xc Y Xc Xc
hemophilia)
XH Y XH XH
- XH Xh
Xh Y Xh Xh
G-6-PD glucose-6-
phosphase dehydrogenase deficiency)
XG Y XG XG
3. - XG Xg
Xg Y Xg Xg
XC Y + Xc Xc
XC , Y + Xc (2x1=2)
XC Xc , Xc Y 100%
100
Xh Y + XH Xh
Xh , Y + X H , Xh (2x2=4)
XH Xh , Xh Xh , XH Y , Xh Y 50%
50%
50% 50%
G-6-PD G-6-PD
XG Y + X g Xg
XG , Y + Xg (2x1=2)
XG Xg , Xg Y 100%
100%
Karyotype
XY XX
ZZ ZW