Y11C - Allergy & AwarenessrebeccaytsangThe document discusses allergies, providing statistics showing that 55% of people have allergies and 33% develop one food allergy. It then discusses common food allergies like shellfish, milk, peanuts, wheat and eggs. It also discusses skin conditions like atopic dermatitis and contact dermatitis. Other sections cover signs and symptoms of allergies, causes of allergies including genetic and environmental factors, treatments, prevention methods, and allergy tests. It notes allergies can affect daily life through disrupted sleep and limited activities.
1. allergic rhinitisFahad ZakwanAllergic rhinitis is a hypersensitivity reaction of the nasal mucosa to allergens like pollen or dust mites. It causes sneezing, runny nose, nasal itching and congestion. Diagnosis involves assessing symptoms and examining the nose for swelling and discharge. Skin or blood tests can identify allergens. Treatment includes allergen avoidance, oral antihistamines like cetirizine or leukotriene inhibitors like montelukast, intranasal steroids, and immunotherapy for long term management.
Montair (Montelukast Sodium Tablets)Clearsky PharmacyMontair (Montelukast Sodium tablets) is used for the prevention and chronic treatment of asthma, exercise-induced bronchoconstriction (EIB), seasonal allergic rhinitis and perennial allergic rhinitis
7.a. histamine & antihistaminicsIAU DentHistamine is a biologically active amine released from mast cells and basophils in response to allergens and other stimuli, causing allergic reactions and lowering blood pressure. It binds to H1 and H2 receptors. H1 receptors mediate allergic symptoms, lowering blood pressure, bronchoconstriction, and gastric acid secretion. Antihistamines like chlorpheniramine and loratadine block H1 receptors, treating allergies, motion sickness, and insomnia with varying side effects. H2 receptor blockers like cimetidine and ranitidine inhibit gastric acid secretion, treating ulcers and reflux. Second generation antihistamines have fewer anticholinergic and sedative side
Levocetirizine+montelukast fdcMalay SinghThis document discusses levocetirizine and montelukast fixed dose combination for the treatment of allergic rhinitis. It provides background on allergic rhinitis and the role of leukotrienes in causing inflammation. Newer generation oral antihistamines like levocetirizine are recommended as first-line treatment. Montelukast is an anti-leukotriene agent that acts on the cysteinyl leukotriene receptor. The document examines the market for fixed dose combinations of levocetirizine and montelukast in India, finding it is growing rapidly at 69% annually with Montair-LC as the current leading brand. Major prescribers of the fixed dose
Antihistamines - PharmacologyAreej Abu HaniehHistamine is a chemical messenger that mediates allergic and inflammatory reactions. It is synthesized and stored in mast cells and basophils before being released in response to stimuli. Histamine binds to H1, H2, H3, and H4 receptors, with the H1 and H2 receptors being clinically relevant drug targets. Antihistamines are used to treat allergic conditions by blocking H1 receptors, and H2 receptor blockers inhibit gastric acid secretion. First-generation antihistamines have greater sedative and anticholinergic side effects than second-generation drugs due to interactions with other receptors.
Histamine pharmacologytushar gosaiThis document summarizes information about histamine and H1 receptor antagonists (antihistamines). It discusses:
1) Histamine's roles in allergy, inflammation, and gastric acid secretion. It acts through four G protein-coupled receptors (H1, H2, H3, H4) and is involved in processes like bronchoconstriction and vasodilation.
2) The locations of histamine synthesis and storage, as well as its role in allergic responses through mast cell degranulation.
3) First and second generation H1 receptor antagonists, how they differ in sedative effects and anticholinergic properties, and their uses in treating allergic disorders
Histamine and antihistaminicsNaser TadviJohn, a 24-year old male, suffers from seasonal allergic rhinitis every winter causing a runny nose, itchy eyes, and sneezing. He takes an over-the-counter antihistamine, diphenhydramine, to relieve his symptoms but it causes drowsiness and dry mouth. His doctor prescribes loratadine which effectively treats his allergies without side effects. Histamine is released during allergic reactions, binding to H1 receptors and causing symptoms. First-generation antihistamines like diphenhydramine relieve symptoms by blocking H1 receptors but cross the blood-brain barrier, while second-generation drugs like loratadine do not cross
Pharmacology Respiratory Drugspinoy nurzeThe document discusses several classes of drugs used to treat respiratory conditions:
1) Antihistamines are used to treat allergic conditions by blocking histamine. First generation causes more side effects like sedation.
2) Antitussives suppress cough reflex. Benzonatate and codeine are examples.
3) Bronchodilators like xanthines and beta-agonists open constricted airways. Theophylline is a xanthine that stimulates respiration but needs monitoring to avoid toxicity.
4) Expectorants and mucolytics help clear secretions by loosening mucus. Acetylcysteine is a mucolytic.
5) Drugs for
Y11C - Allergy & AwarenessrebeccaytsangThe document discusses allergies, providing statistics showing that 55% of people have allergies and 33% develop one food allergy. It then discusses common food allergies like shellfish, milk, peanuts, wheat and eggs. It also discusses skin conditions like atopic dermatitis and contact dermatitis. Other sections cover signs and symptoms of allergies, causes of allergies including genetic and environmental factors, treatments, prevention methods, and allergy tests. It notes allergies can affect daily life through disrupted sleep and limited activities.
1. allergic rhinitisFahad ZakwanAllergic rhinitis is a hypersensitivity reaction of the nasal mucosa to allergens like pollen or dust mites. It causes sneezing, runny nose, nasal itching and congestion. Diagnosis involves assessing symptoms and examining the nose for swelling and discharge. Skin or blood tests can identify allergens. Treatment includes allergen avoidance, oral antihistamines like cetirizine or leukotriene inhibitors like montelukast, intranasal steroids, and immunotherapy for long term management.
Montair (Montelukast Sodium Tablets)Clearsky PharmacyMontair (Montelukast Sodium tablets) is used for the prevention and chronic treatment of asthma, exercise-induced bronchoconstriction (EIB), seasonal allergic rhinitis and perennial allergic rhinitis
7.a. histamine & antihistaminicsIAU DentHistamine is a biologically active amine released from mast cells and basophils in response to allergens and other stimuli, causing allergic reactions and lowering blood pressure. It binds to H1 and H2 receptors. H1 receptors mediate allergic symptoms, lowering blood pressure, bronchoconstriction, and gastric acid secretion. Antihistamines like chlorpheniramine and loratadine block H1 receptors, treating allergies, motion sickness, and insomnia with varying side effects. H2 receptor blockers like cimetidine and ranitidine inhibit gastric acid secretion, treating ulcers and reflux. Second generation antihistamines have fewer anticholinergic and sedative side
Levocetirizine+montelukast fdcMalay SinghThis document discusses levocetirizine and montelukast fixed dose combination for the treatment of allergic rhinitis. It provides background on allergic rhinitis and the role of leukotrienes in causing inflammation. Newer generation oral antihistamines like levocetirizine are recommended as first-line treatment. Montelukast is an anti-leukotriene agent that acts on the cysteinyl leukotriene receptor. The document examines the market for fixed dose combinations of levocetirizine and montelukast in India, finding it is growing rapidly at 69% annually with Montair-LC as the current leading brand. Major prescribers of the fixed dose
Antihistamines - PharmacologyAreej Abu HaniehHistamine is a chemical messenger that mediates allergic and inflammatory reactions. It is synthesized and stored in mast cells and basophils before being released in response to stimuli. Histamine binds to H1, H2, H3, and H4 receptors, with the H1 and H2 receptors being clinically relevant drug targets. Antihistamines are used to treat allergic conditions by blocking H1 receptors, and H2 receptor blockers inhibit gastric acid secretion. First-generation antihistamines have greater sedative and anticholinergic side effects than second-generation drugs due to interactions with other receptors.
Histamine pharmacologytushar gosaiThis document summarizes information about histamine and H1 receptor antagonists (antihistamines). It discusses:
1) Histamine's roles in allergy, inflammation, and gastric acid secretion. It acts through four G protein-coupled receptors (H1, H2, H3, H4) and is involved in processes like bronchoconstriction and vasodilation.
2) The locations of histamine synthesis and storage, as well as its role in allergic responses through mast cell degranulation.
3) First and second generation H1 receptor antagonists, how they differ in sedative effects and anticholinergic properties, and their uses in treating allergic disorders
Histamine and antihistaminicsNaser TadviJohn, a 24-year old male, suffers from seasonal allergic rhinitis every winter causing a runny nose, itchy eyes, and sneezing. He takes an over-the-counter antihistamine, diphenhydramine, to relieve his symptoms but it causes drowsiness and dry mouth. His doctor prescribes loratadine which effectively treats his allergies without side effects. Histamine is released during allergic reactions, binding to H1 receptors and causing symptoms. First-generation antihistamines like diphenhydramine relieve symptoms by blocking H1 receptors but cross the blood-brain barrier, while second-generation drugs like loratadine do not cross
Pharmacology Respiratory Drugspinoy nurzeThe document discusses several classes of drugs used to treat respiratory conditions:
1) Antihistamines are used to treat allergic conditions by blocking histamine. First generation causes more side effects like sedation.
2) Antitussives suppress cough reflex. Benzonatate and codeine are examples.
3) Bronchodilators like xanthines and beta-agonists open constricted airways. Theophylline is a xanthine that stimulates respiration but needs monitoring to avoid toxicity.
4) Expectorants and mucolytics help clear secretions by loosening mucus. Acetylcysteine is a mucolytic.
5) Drugs for
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