14. Intracranial abscess
Epidural *Epidural *хатуухатуу
хальсан дээрххальсан дээрх
SubduralSubdural хатуухатуу
хальсны дорххальсны дорх
IntracranialIntracranial
БайрлалБайрлал
Гавлын ясны дотор
хана , хатуу хальсны
хооронд
Хатуу , зөөлөн
бүрхүүлийн завсар
Дух, дух чамархайн
хэсэгт
хар/ цагаан бодис
явцявц Аажим, тэлэх
Нэвчиж, нэг тал
бөмбөлгийн хамарна
Шинж тэмдэггүй,
нэмэгдэх
ШинжШинж
тэмдэгтэмдэг
Хөнгөн , non-specific for
weeks. Increase ICP
Meningismus, rapid
progression to coma
Subtle if frontal (mood)
H/A, lethargy, seizures,
focal deficits
DiagnosisDiagnosis CT or MRI
CT may show it but MRI
is better
MRI (T2)
Hypointense with
capsule
TreatmentTreatment
IV Abx. + Surgery
(craniotomy / ESS)
IV Abx., craniotomy,
ESS, anticonvulsivants,
+/- steroids
ESS / Neurosurgery
(stereotactic vs. open)
Editor's Notes
Not exclusive, can occur concurrently
Percentages in children (Hicks et al, 2011)
Also incidence of neurologic sequelae such as hearing loss and seizure disorder.
Will likely need antibiotics for 4-8 weeks; usually vancomycin and 3rd or 4th generation cephalosporin
Prophylactic seizure therapy not necessary unless there’s an associated subdural abscess.
Generally unilateral
May have mood swings and behavioral changes with frontal lobe involvement
Worsening headache with meningismus suggests possible rupture of the abscess.
Antibiotic regimen is typically 6-8 weeks; typically ceftriaxone, vancomycin or nafcillin, and metronidazole
Corticosteroid use is controversial. Steroids can retard the encapsulation process, increase necrosis, reduce antibiotic penetration into the abscess, increase the risk of ventricular rupture, and alter the appearance on CT scans. Steroid therapy can also produce a rebound effect when discontinued. If used to reduce cerebral edema, therapy should be of short duration. The appropriate dosage, the proper timing, and any effect of steroid therapy on the course of the disease are unknown.
The procedures used are aspiration through a bur hole and complete excision after craniotomy.
Aspiration is the most common procedure and is often performed using a stereotactic procedure with the guidance of CT scanning or MRI.