Sunlows feb2014
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The document announces a presentation on February 28th from 2-4pm about using financial incentives to improve medication adherence for patients with severe mental illnesses. The presentation will summarize the debate around using such incentives, present views from a focus group study, and show results from a randomized controlled trial where incentives significantly improved medication adherence over one year. Implications for clinical practice will also be discussed.
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油
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Nicola fear fast rMHRN South London & South East Hub
油
FAST-R provides helpful advice to researchers from those with experience of mental health issues in three key roles: as a PI/researcher, supervisor, and ethics committee member. It offers expertise to improve patient information sheets and recruitment strategies, allows demonstration of patient involvement, acts as an extra check for student research, and increases confidence in research proposals, providing a smoother ethics review process. The document concludes that FAST-R does truly help researchers as it is fast, free, and provides useful advice.Nicol ferrier mhrn mar13
Nicol ferrier mhrn mar13MHRN South London & South East Hub
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The document discusses research on the hypothalamic-pituitary-adrenal (HPA) axis and its relationship to mood disorders. It finds that HPA axis hormones and receptors are abnormal in affective disorders. Studies show hypercortisolaemia in bipolar disorder patients across depressive, hypomanic and euthymic states. Administration of glucocorticoids impairs cognition and mood in patients and animal models. A clinical trial found that mifepristone, which blocks glucocorticoid receptors, improved spatial working memory performance in bipolar patients relative to placebo.Mhrn presentation oram
Mhrn presentation oramMHRN South London & South East Hub
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Mental health services in South London are providing care for trafficked individuals. Preliminary findings show that compared to non-trafficked patients, trafficked individuals are more likely to be referred through maternity services and experience detention under the Mental Health Act or adverse pathways involving police intervention. The study aims to better understand the needs and experiences of trafficked individuals within mental health systems to improve identification and care.Mhrn liam ennis
Mhrn liam ennisMHRN South London & South East Hub
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This study analyzed data from 374 projects in the MHRN portfolio database to examine trends in service user involvement and its association with study success. The results showed that service user involvement has increased slightly over time. Higher levels of involvement were predicted by certain funders and clinical study groups. Studies with jointly or service user-initiated collaboration were more likely to successfully recruit over 90% of their target sample size. However, the study noted limitations and more research is needed to fully understand the relationship between involvement and recruitment success.John strang-0313min
John strang-0313minMHRN South London & South East Hub
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The document summarizes Professor John Strang's work in three areas of addiction:
1. RIOTT: A randomized trial of supervised heroin prescribing for chronic refractory heroin addicts. The trial found that the supervised heroin (SIH) group had the strongest treatment outcomes while supervised injectable methadone (SIM) was better than the control group.
2. ConMan: A research program developing the UK evidence base for using contingency management techniques to improve outcomes in addiction treatments. It is funded by the NIHR.
3. N-ALIVE: A randomized trial of take-home naloxone to prevent post-prison overdose deaths. Diana rose mhrn 2013
Diana rose mhrn 2013MHRN South London & South East Hub
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This document discusses the history and development of user involvement in mental health research. It traces how user-led research projects in the 1990s influenced the establishment of organizations promoting consumer involvement in research. Over time, some user researchers moved into academia to conduct research from a user perspective. New methodologies have also emerged that incorporate the user voice, such as patient-centered systematic reviews and patient-generated outcome measures. The document argues that user involvement has the potential to make research knowledge more complete by providing alternative standpoints and contesting mainstream discourses.Landau dunn 20march2013
Landau dunn 20march2013MHRN South London & South East Hub
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This document provides an outline of a conference presentation on evaluating moderation and mediation in personalized therapies. The presentation aims to: 1) introduce key concepts of personalized therapy/stratified medicine, causal effects, confounding and RCTs; 2) recap and develop ideas on correct and incorrect approaches to evaluating treatment effect moderation and using interactions to study mediation; and 3) briefly describe the research program evaluating efficacy and mechanisms of complex interventions funded by the MRC Methodology Research Programme.Scientific mtgpres2013
Scientific mtgpres2013MHRN South London & South East Hub
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This document discusses engaging people in mental health research. It outlines the importance of research and a pragmatic science approach. Examples of engagement activities are provided, as well as the MHRN engagement strategy and evaluation of the strategy. The key points are that research allows the NHS to make discoveries that improve health and wellbeing, but this requires a high level of engagement from various stakeholders. The MHRN engagement strategy outlines seven work streams to increase engagement in research.Smoking cessation and mental ill health
Smoking cessation and mental ill healthMHRN South London & South East Hub
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- Smoking rates are much higher in people with serious mental illness (SMI) compared to the general population, contributing significantly to poor physical health outcomes and reduced life expectancy in people with SMI.
- Evidence from randomized controlled trials shows that smoking cessation interventions combining nicotine replacement therapy (NRT) and/or bupropion with behavioral support can help people with SMI quit smoking, with odds ratios for abstinence between 2-10 times higher than control groups.
- The most effective interventions provide combinations of pharmacotherapy (NRT and/or bupropion) along with individual or group behavioral support. These interventions show potential for reducing smoking rates and improving health outcomes in people withSz and experimental medicine
Sz and experimental medicineMHRN South London & South East Hub
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This document discusses recent developments in experimental medicine for schizophrenia. It summarizes research on using pharmacogenomics and proteomics to predict prognosis, response to treatment, and identify biomarkers. It also mentions several recent clinical trials testing new agents, biomarkers, and trial designs. The document reviews studies on weight gain, metformin, EPA, cannabidiol, oxytocin, and other potential adjunctive treatments. It discusses using novel technologies like mobile health apps and progress on cognitive remediation plus cognitive-enhancing therapy or CBT.Mhrn dv and mental health lmh
Mhrn dv and mental health lmhMHRN South London & South East Hub
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This document discusses domestic violence and its relationship to mental health. It notes that domestic violence is associated with an increased risk of various mental disorders in both men and women. Experiencing domestic violence is also linked to poorer mental health outcomes. While the causal relationship is complex, domestic violence appears to increase the severity of mental health symptoms. The document then reviews prevalence rates of domestic violence among mental health patients and barriers to disclosure. It concludes by discussing interventions for domestic violence survivors with mental illness, including trauma-focused cognitive behavioral therapy and advocacy services integrated within mental health teams.Mhrn addictions-0313min
Mhrn addictions-0313minMHRN South London & South East Hub
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This document summarizes Professor John Strang's work in three areas of addiction research:
1. RIOTT: A randomized trial of supervised heroin prescribing for chronic refractory heroin addicts. The trial found the strongest outcomes in the heroin group, with the methadone group also outperforming the control group.
2. ConMan: A research program developing the UK evidence base for using contingency management techniques to improve outcomes in addiction treatments.
3. N-ALIVE: A randomized trial of take-home naloxone to prevent post-prison overdose deaths.J. secker mhrn presentation
J. secker mhrn presentationMHRN South London & South East Hub
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The document summarizes a study on the experiences of people with mental health issues returning to paid employment. It found that while participants initially feared disclosure of their mental health issues, most received reassuring responses from employers. It also found that jobs provided mental health benefits like improved confidence and stability. However, some participants faced unsupportive work environments or discrimination. Effective employment support was important in helping overcome barriers and find satisfying jobs that enhanced well-being.Ad
Sunlows feb2014
- 1. FRIDAY FEBRUARY 28TH 2-4PM Financial incentives have been considered as a notion to improve medication adherence in patients with severe mental illnesses. There has been a lively debate with strong opinions expressed in favour and against using such incentives. The presentation will summarise the argument about the use of financial incentives; present views of stakeholders obtained in a focus group study; and show the results of a randomised controlled trial (FIAT) testing the effectiveness of financial incentives to improve adherence to antipsychotic maintenance medication over a one year period. In the trial, incentives led to a significant improvement in medication adherence. Implications for practice will be discussed. Room 1.17, Franklin-Wilkins building, Waterloo Campus, Stamford Street, London SE1 8WA Please call or email to book a place: 020 7848 5015 www.sunlows.org.uk ----- info@sunlows.org.uk Future SUNLOWS dates for your diary: Friday 28th March Friday 25th April We always value your feedback! The Mental Health Research Network is part of the NIHR Clinical Research Network, which supports research to make patients, and the NHS, better. MHRN South London & South East Hub Financial incentives to improve medication adherence: presented by Professor Stefan Priebe @MHRNSLSEHub SUNLOWS TRIES TO MAKE THE SUBJECT OF RESEARCH USER-FRIENDLY Follow the South London & South East Hub on Twitter and Facebook: SUNLOWS