This document provides background information on lower limb amputations. It discusses the history of amputation dating back to ancient times and developments over centuries. It defines amputation, provides classifications, and outlines epidemiology, indications, investigations, surgical principles, complications and prognosis of lower limb amputations. The document discusses various types of foot, midfoot, hindfoot and above-knee amputations and their techniques.
We know that the past is our foundation for future developments. We must build upon it so that we too can act as a stable foundation for future generations. One must be aware of the way surgeons in the past have contributed to Orthopaedics.
This presentation is a brief historical review Mankind's cumulative experience in fracture management which was Started by the Ancient very primitive trials and ended by the presence of Robotic and Telesurgery the so called Remote surgery.
This document provides an overview of the history and process of embalming. It discusses how embalming began in Ancient Egypt and was later adopted during the U.S. Civil War to preserve soldiers' bodies. The document also profiles Thomas Holmes, considered the father of modern embalming, and Roy F. McCampbell, who experimented with using electricity for embalming. Finally, it notes that while traditionally practiced mostly by white men, some of the first African American and women embalmers also made contributions to the field. However, embalming remains an expensive optional procedure for funeral preparation today.
BRIEF HISTORY OF SURGERY-S1 LECTURE.pptxFeniksRetails
油
Surgery has evolved significantly from ancient times to modern times. Early surgery lacked anatomical knowledge and was advanced by individuals during wars. Ancient Egyptians and Greeks contributed to early understanding of anatomy and treatment methods. During the Middle Ages, barber-surgeons performed simple procedures and Vesalius helped disprove some of Galen's theories. Major advances in the 19th century included anesthesia, antisepsis, and sterilization. The 20th century saw developments like organ transplantation, minimally invasive techniques, and robotics. Modern surgery is highly specialized and collaborative, involving many related medical and technological fields.
This document discusses the history and principles of skin flaps. It begins by defining flaps and grafts, and outlines the early history of flap surgery from 600 BC to the 19th century. Key figures and their contributions are highlighted, such as Sushruta describing nose reconstruction using a forehead flap. The document then discusses classifications of flaps based on vascularity, movement, and composition. Common flap types like random flaps, axial flaps, and pedicled flaps are described. Methods of flap movement including advancement, pivot, and transposition flaps are also summarized.
Competitive swimming began in Britain in the 1830s using breaststroke. The first modern Olympics in 1896 included swimming events. FINA was formed in 1908 to govern international swimming competitions. Early swimming books from the 1500s-1800s described swimming techniques like breaststroke and provided safety advice. Front crawl became popular in the late 1800s after being observed in South America. The first channel swim was completed in 1875 using breaststroke. Olympic swimming grew with the addition of events in 1900 and the introduction of backstroke.
The document provides a history of anesthesia, covering developments from ancient times through the 20th century. It discusses early non-drug pain management techniques and the discovery of anesthetic agents such as nitrous oxide, ether, and chloroform. Key developments included Morton's public demonstration of ether anesthesia in 1846, the introduction of tracheal intubation in the late 19th century, advances in ventilation equipment and patient monitoring, and the discovery and use of muscle relaxants and intravenous anesthetics. The history shows how anesthesia evolved from simple restraint to a specialized field utilizing various drugs, equipment, and techniques.
This document provides tips for using a PowerPoint presentation (PPT) for active learning sessions:
1. The PPT can be freely downloaded, edited, and modified.
2. Many slides are intentionally blank except for the title to engage students in filling gaps.
3. The instructor should first show blank slides to elicit what students already know, then show the content slide.
4. This process repeats to reinforce learning over three iterations. It is good for individual study as well.
This document provides tips for using a PowerPoint presentation (PPT) for active learning sessions. It recommends:
1. Freely downloading, editing, and modifying the PPT and adding your name.
2. Not worrying about the number of slides, as half are blank except for the title to facilitate questions.
3. First showing blank slides related to topics, asking students what they know, and then showing slides with information.
4. Rerunning the show at the end by again showing blank slides and soliciting questions before providing the answers.
This approach allows for active revision in learning about a topic over three iterations. The PPT can also be used for self-study.
Evolution of Surgery from beginning to todayTanvirIslam94
油
The document summarizes the evolution of surgery from ancient times to the present. Some key developments include the first trepanation procedures in ancient Egypt, advances during the 19th century like the first use of anesthesia and antiseptics, and modern innovations like laparoscopic and robotic surgery. Major surgical achievements accelerated during each era as knowledge and technology progressed.
A presentation on various instruments used in surgery..The presentation is about type of instruments their uses and any modifications. It's helpful for a surgery pg student.
The document discusses various types of skin flaps used in reconstructive surgery. It defines a flap as a unit of tissue transferred from a donor site to a recipient site while maintaining its own blood supply. It then summarizes several types of local flaps used in reconstruction including advancement flaps, V-Y flaps, transposition flaps, and Z-plasties. The document also discusses regional flaps as well as modifications to flaps including flap delay and tissue expansion.
Surgery has evolved greatly over thousands of years from early practices of wound treatment and basic procedures to become a complex medical specialty. The document traces the history of surgery from ancient civilizations like Egypt, India, Greece and Rome where the first depictions and medical texts of surgical practices emerged. It describes the developments during the Renaissance with anatomists like da Vinci and the advances made due to military and non-military surgeons. The modern concepts of antisepsis, anesthesia and hospitals are reviewed along with pioneering surgeons who contributed innovative procedures and improved outcomes. The scope of surgery continues to grow with new techniques and subspecialties arising to address various health issues effectively.
This document provides a classification and overview of burn injuries. It discusses:
1. The classification of burns based on etiology including thermal, electrical, chemical, radiation, and inhalation injuries.
2. The degrees of burn injuries from first to fourth degree based on depth of tissue damage.
3. Key aspects of burn management including emergent resuscitation focusing on airway, circulation and fluid replacement to maintain organ function in the first 24-48 hours.
4. Wound care including open and closed methods and use of antimicrobial agents like silver sulfadiazine cream.
This document provides information on burns, including:
1. It defines burns as tissue damage caused by heat, radiation, chemicals or electricity. Burns can range from minor to life-threatening depending on their location and severity.
2. It describes the three layers of skin and explains how burns can damage the epidermis, dermis or deeper tissues.
3. It classifies burns based on their depth of tissue damage, ranging from superficial first degree burns only affecting the epidermis to full thickness third degree burns extending into muscle or bone. More severe burns require immediate medical attention.
The document discusses surgical site infections and sterilization. It defines surgical site infections and outlines their epidemiology, including that they are the most common hospital acquired infection. It describes the criteria for defining surgical site infections, including superficial, deep and organ/space infections. It also discusses the pathogenesis of surgical site infections and factors that determine risk, and recommendations for prevention including proper sterilization techniques.
This document discusses surgical site infections and sterilization. It provides definitions and classifications of surgical site infections, including superficial incisional, deep incisional, and organ/space infections. It discusses the epidemiology of surgical site infections, noting they are one of the most common hospital acquired infections. It also outlines recommendations and best practices for prevention of surgical site infections, including proper sterilization techniques, optimal surgical environment and practices, and appropriate use of antibiotics. Prevention is aimed at avoiding contamination from endogenous or exogenous sources of infection.
This document discusses various methods of sterilization including physical and chemical agents. Physical agents include dry heat (hot air ovens, flaming, incineration), moist heat (pasteurization, boiling, steam), filtration, radiation, and ultrasound. Moist heat via autoclaving is the most reliable sterilization method. Chemical agents discussed are alcohols, aldehydes, dyes, halogens, phenols, and gases. The document defines key sterilization terms and explains the mechanisms of different sterilization methods.
Dr. Ibrahim's presentation covered sterilization methods used in medical applications. It discussed the importance of sterilization in preventing disease transmission and the need to eliminate microorganisms from medical tools and devices. Three main sterilization methods were outlined - physical, chemical, and mechanical. Physical methods included dry heat, moist heat and radiation sterilization. Chemical methods included the use of ethylene oxide and disinfectants. Mechanical sterilization involves passing solutions through filters. The presentation concluded by discussing some effects of sterilization and future prospects for more reliable and cost-effective sterilization processes.
This document discusses various methods of sterilization, including physical methods like heat, radiation, filtration and chemical methods. Heat-based methods include dry heat using an oven or flame and moist heat using autoclaving, boiling, or pasteurization. Radiation methods use gamma rays, UV light, or infrared radiation. Filtration can sterilize heat-sensitive solutions using depth or membrane filters. Common chemical sterilization methods involve the use of chemicals like ethylene oxide, hydrogen peroxide, or glutaraldehyde. The Most Probable Number technique and Membrane Filter technique are also discussed for enumerating bacteria in water samples.
Dr. Ibrahim presented on various sterilization methods including physical agents like heat, radiation, and filtration as well as chemical agents like alcohols, aldehydes, and gases. The most common sterilization methods used in laboratories are moist heat using an autoclave at 121属C for 15 minutes or 134属C for 3 minutes, dry heat using a hot air oven at 160-180属C, and chemical methods using ethylene oxide or beta propiolactone gases. Proper testing of sterilization efficacy includes using chemical, mechanical, and biological indicators to confirm sterilizing conditions have been met.
Dr. Ibrahim presented on various sterilization methods including physical agents like heat, radiation, and filtration as well as chemical agents like alcohols, aldehydes, and gases. The most common sterilization methods used in laboratories are moist heat using an autoclave at 121属C for 15 minutes or 134属C for 3 minutes, dry heat using a hot air oven at 160-180属C, and chemical methods using ethylene oxide or beta propiolactone gases. Proper testing of sterilization efficacy includes using chemical, mechanical, and biological indicators to confirm sterilizing conditions have been met.
Surgical site infection is a major problem accounting for 15-25% of all surgical infections and increased healthcare costs. A surgical site infection is defined as an infected incised wound or deep organ space resulting from the invasion of organisms through tissues following a breakdown of local and systemic host defenses, leading to local and systemic symptoms. Important definitions include surgical site infection (SSI), systemic inflammatory response syndrome (SIRS) which is the body's response to an infected wound, multiple organ dysfunction syndrome (MODS) which is the effect of the infection systemically, and multiple organ failure syndrome (MOFS) which is the end-stage of uncontrolled MODS.
This funding allowed Sentara Healthcare to take a systems approach to implementing NHSN surgical site infection (SSI) surveillance. They used $124,000 for information technology assistance to develop an electronic process for exporting surgical procedure data directly into NHSN. They also used $21,000 to train infection prevention and control staff as well as data auditors on SSI surveillance. This funding demonstrated how a large healthcare system can collaborate across departments like IT, infection prevention, and data auditors to efficiently implement NHSN reporting requirements.
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Competitive swimming began in Britain in the 1830s using breaststroke. The first modern Olympics in 1896 included swimming events. FINA was formed in 1908 to govern international swimming competitions. Early swimming books from the 1500s-1800s described swimming techniques like breaststroke and provided safety advice. Front crawl became popular in the late 1800s after being observed in South America. The first channel swim was completed in 1875 using breaststroke. Olympic swimming grew with the addition of events in 1900 and the introduction of backstroke.
The document provides a history of anesthesia, covering developments from ancient times through the 20th century. It discusses early non-drug pain management techniques and the discovery of anesthetic agents such as nitrous oxide, ether, and chloroform. Key developments included Morton's public demonstration of ether anesthesia in 1846, the introduction of tracheal intubation in the late 19th century, advances in ventilation equipment and patient monitoring, and the discovery and use of muscle relaxants and intravenous anesthetics. The history shows how anesthesia evolved from simple restraint to a specialized field utilizing various drugs, equipment, and techniques.
This document provides tips for using a PowerPoint presentation (PPT) for active learning sessions:
1. The PPT can be freely downloaded, edited, and modified.
2. Many slides are intentionally blank except for the title to engage students in filling gaps.
3. The instructor should first show blank slides to elicit what students already know, then show the content slide.
4. This process repeats to reinforce learning over three iterations. It is good for individual study as well.
This document provides tips for using a PowerPoint presentation (PPT) for active learning sessions. It recommends:
1. Freely downloading, editing, and modifying the PPT and adding your name.
2. Not worrying about the number of slides, as half are blank except for the title to facilitate questions.
3. First showing blank slides related to topics, asking students what they know, and then showing slides with information.
4. Rerunning the show at the end by again showing blank slides and soliciting questions before providing the answers.
This approach allows for active revision in learning about a topic over three iterations. The PPT can also be used for self-study.
Evolution of Surgery from beginning to todayTanvirIslam94
油
The document summarizes the evolution of surgery from ancient times to the present. Some key developments include the first trepanation procedures in ancient Egypt, advances during the 19th century like the first use of anesthesia and antiseptics, and modern innovations like laparoscopic and robotic surgery. Major surgical achievements accelerated during each era as knowledge and technology progressed.
A presentation on various instruments used in surgery..The presentation is about type of instruments their uses and any modifications. It's helpful for a surgery pg student.
The document discusses various types of skin flaps used in reconstructive surgery. It defines a flap as a unit of tissue transferred from a donor site to a recipient site while maintaining its own blood supply. It then summarizes several types of local flaps used in reconstruction including advancement flaps, V-Y flaps, transposition flaps, and Z-plasties. The document also discusses regional flaps as well as modifications to flaps including flap delay and tissue expansion.
Surgery has evolved greatly over thousands of years from early practices of wound treatment and basic procedures to become a complex medical specialty. The document traces the history of surgery from ancient civilizations like Egypt, India, Greece and Rome where the first depictions and medical texts of surgical practices emerged. It describes the developments during the Renaissance with anatomists like da Vinci and the advances made due to military and non-military surgeons. The modern concepts of antisepsis, anesthesia and hospitals are reviewed along with pioneering surgeons who contributed innovative procedures and improved outcomes. The scope of surgery continues to grow with new techniques and subspecialties arising to address various health issues effectively.
This document provides a classification and overview of burn injuries. It discusses:
1. The classification of burns based on etiology including thermal, electrical, chemical, radiation, and inhalation injuries.
2. The degrees of burn injuries from first to fourth degree based on depth of tissue damage.
3. Key aspects of burn management including emergent resuscitation focusing on airway, circulation and fluid replacement to maintain organ function in the first 24-48 hours.
4. Wound care including open and closed methods and use of antimicrobial agents like silver sulfadiazine cream.
This document provides information on burns, including:
1. It defines burns as tissue damage caused by heat, radiation, chemicals or electricity. Burns can range from minor to life-threatening depending on their location and severity.
2. It describes the three layers of skin and explains how burns can damage the epidermis, dermis or deeper tissues.
3. It classifies burns based on their depth of tissue damage, ranging from superficial first degree burns only affecting the epidermis to full thickness third degree burns extending into muscle or bone. More severe burns require immediate medical attention.
The document discusses surgical site infections and sterilization. It defines surgical site infections and outlines their epidemiology, including that they are the most common hospital acquired infection. It describes the criteria for defining surgical site infections, including superficial, deep and organ/space infections. It also discusses the pathogenesis of surgical site infections and factors that determine risk, and recommendations for prevention including proper sterilization techniques.
This document discusses surgical site infections and sterilization. It provides definitions and classifications of surgical site infections, including superficial incisional, deep incisional, and organ/space infections. It discusses the epidemiology of surgical site infections, noting they are one of the most common hospital acquired infections. It also outlines recommendations and best practices for prevention of surgical site infections, including proper sterilization techniques, optimal surgical environment and practices, and appropriate use of antibiotics. Prevention is aimed at avoiding contamination from endogenous or exogenous sources of infection.
This document discusses various methods of sterilization including physical and chemical agents. Physical agents include dry heat (hot air ovens, flaming, incineration), moist heat (pasteurization, boiling, steam), filtration, radiation, and ultrasound. Moist heat via autoclaving is the most reliable sterilization method. Chemical agents discussed are alcohols, aldehydes, dyes, halogens, phenols, and gases. The document defines key sterilization terms and explains the mechanisms of different sterilization methods.
Dr. Ibrahim's presentation covered sterilization methods used in medical applications. It discussed the importance of sterilization in preventing disease transmission and the need to eliminate microorganisms from medical tools and devices. Three main sterilization methods were outlined - physical, chemical, and mechanical. Physical methods included dry heat, moist heat and radiation sterilization. Chemical methods included the use of ethylene oxide and disinfectants. Mechanical sterilization involves passing solutions through filters. The presentation concluded by discussing some effects of sterilization and future prospects for more reliable and cost-effective sterilization processes.
This document discusses various methods of sterilization, including physical methods like heat, radiation, filtration and chemical methods. Heat-based methods include dry heat using an oven or flame and moist heat using autoclaving, boiling, or pasteurization. Radiation methods use gamma rays, UV light, or infrared radiation. Filtration can sterilize heat-sensitive solutions using depth or membrane filters. Common chemical sterilization methods involve the use of chemicals like ethylene oxide, hydrogen peroxide, or glutaraldehyde. The Most Probable Number technique and Membrane Filter technique are also discussed for enumerating bacteria in water samples.
Dr. Ibrahim presented on various sterilization methods including physical agents like heat, radiation, and filtration as well as chemical agents like alcohols, aldehydes, and gases. The most common sterilization methods used in laboratories are moist heat using an autoclave at 121属C for 15 minutes or 134属C for 3 minutes, dry heat using a hot air oven at 160-180属C, and chemical methods using ethylene oxide or beta propiolactone gases. Proper testing of sterilization efficacy includes using chemical, mechanical, and biological indicators to confirm sterilizing conditions have been met.
Dr. Ibrahim presented on various sterilization methods including physical agents like heat, radiation, and filtration as well as chemical agents like alcohols, aldehydes, and gases. The most common sterilization methods used in laboratories are moist heat using an autoclave at 121属C for 15 minutes or 134属C for 3 minutes, dry heat using a hot air oven at 160-180属C, and chemical methods using ethylene oxide or beta propiolactone gases. Proper testing of sterilization efficacy includes using chemical, mechanical, and biological indicators to confirm sterilizing conditions have been met.
Surgical site infection is a major problem accounting for 15-25% of all surgical infections and increased healthcare costs. A surgical site infection is defined as an infected incised wound or deep organ space resulting from the invasion of organisms through tissues following a breakdown of local and systemic host defenses, leading to local and systemic symptoms. Important definitions include surgical site infection (SSI), systemic inflammatory response syndrome (SIRS) which is the body's response to an infected wound, multiple organ dysfunction syndrome (MODS) which is the effect of the infection systemically, and multiple organ failure syndrome (MOFS) which is the end-stage of uncontrolled MODS.
This funding allowed Sentara Healthcare to take a systems approach to implementing NHSN surgical site infection (SSI) surveillance. They used $124,000 for information technology assistance to develop an electronic process for exporting surgical procedure data directly into NHSN. They also used $21,000 to train infection prevention and control staff as well as data auditors on SSI surveillance. This funding demonstrated how a large healthcare system can collaborate across departments like IT, infection prevention, and data auditors to efficiently implement NHSN reporting requirements.
Author:
Attuluri Vamsi Kumar
Assistant Professor,
Department of Medical Laboratory Sciences,
Regional Institute of Paramedical and Nursing (RIPANS),
Undertaken by the Ministry of Health and Family Welfare (MoHFW), Govt. of India
LAB MANUAL APPLIED HEMATOLOGY
M.Sc. Medical Laboratory Sciences (Blood Banking)
Department of Medical Lab Sciences
Regional Institute of Paramedical and Nursing (RIPANS)
Undertaken by the Ministry of Health and Family Welfare (MoHFW), Govt. of India
Program Details:
Program Name: M.Sc. MLS (Blood Banking)
Semester: 2
Batch: 2024
Subject Name: Applied Hematology
Subject Code: MLTH-P206
About this Lab Manual:
This Lab Manual on Applied Hematology is designed to serve as a comprehensive practical guide for M.Sc. Medical Laboratory Sciences (Blood Banking) students at RIPANS. It provides a structured framework for laboratory techniques, diagnostic methodologies, and applied hematological procedures, ensuring a hands-on approach to understanding blood-related disorders and transfusion science.
This manual covers advanced hematological investigations, staining techniques, bone marrow examinations, and specialized blood testing methods essential for a professional career in blood banking and hematology laboratories. Each experiment is presented with a detailed principle, methodology, interpretation guidelines, and viva questions, allowing students to grasp fundamental and advanced concepts with ease.
Key Features of this Manual:
鏝 Step-by-Step Experimental Procedures Clear, well-structured protocols to enhance laboratory skills.
鏝 Principles & Applications Explanation of core hematological principles and their real-world applications.
鏝 Clinical Relevance Interpretation of lab findings in diagnosing hematological disorders.
鏝 Observation & Analysis Structured observation tables to record findings systematically.
鏝 Viva Questions & Answer Key Helps in exam preparation and enhances conceptual clarity.
鏝 Reference Textbooks Standard books suggested for further in-depth learning.
Who Should Use This Manual?
This manual is intended for M.Sc. Medical Laboratory Sciences (Blood Banking) students and faculty members at RIPANS. It is a valuable resource for trainees, researchers, and professionals in hematology and transfusion medicine.
Through this structured and practical approach, students will develop a deeper understanding of hematological investigations, laboratory techniques, and diagnostic procedures, ultimately preparing them for clinical, research, and diagnostic settings.
For academic and professional use only.
Top 5 Sexologists in Delhi 2025 | Best Experts in Sexual HealthPawan Kumar
油
Looking for the best sexologists in Delhi? Discover the top 5 experts in sexual health for 2025, specializing in erectile dysfunction, premature ejaculation, low libido, and holistic treatments. Get expert guidance and personalized care today!
Tran Quoc Bao Named Best and Most Influential Hospital CEO in Vietnam by Hosp...Ignite Capital
油
Tran Quoc Bao, named Best and Most Influential Hospital CEO in Vietnam 2025 by Hospital Insight Magazine, is transforming Vietnams healthcare landscape with his unique blend of medical expertise and financial acumen. As CEO of Prima Saigon, the country's leading international daycare and ambulatory hospital, Bao has turned the institution into a benchmark of excellence, setting new standards for innovation and patient care.
His leadership at Prima Saigon has propelled the hospital to the forefront of the Vietnamese healthcare sector, but Bao's impact goes beyond national borders. As a member of the Advisory Board for Asian Hospital & Healthcare Management, a prominent publication influencing global healthcare policy, he is helping to shape trends and set standards that extend across Asia and the world.
With nearly two decades of experience, Bao has held key positions at renowned institutions like City International Hospital, FV Hospital, TMMC Healthcare (Tam Tri Hospital Group), and Cao Tang Hospital, where he led the transformation into Vietnams first Joint Commission International (JCI)-accredited hospital. This milestone put Vietnam firmly on the global healthcare map, thanks to Baos visionary leadership.
His extensive expertise is matched by a distinguished financial background, holding elite credentials such as CFA速, CMT速, CPWA速, FMVA速, and others. Baos strategic approach has allowed him to lead $2 billion in healthcare M&A transactions, reshaping Vietnams healthcare investment landscape. His ability to blend healthcare with finance has earned him recognition as a thought leader in the field.
Bao has also contributed more than 20 articles to major outlets like Forbes, Bloomberg, and Voice of America, sharing his insights on healthcare innovation and investment. His accolades include being named Healthcare Executive of the Year Vietnam 2019, Medical Tourism Leader of the Year 2021, and being honored as a Doing Business 2022 Leader by the World Bank Group.
In addition, Bao's strategic expertise is sought by top global consulting firms like BCG, Bain, and McKinsey, advising on major healthcare investments and partnerships in Asia. With his visionary leadership, Tran Quoc Bao continues to drive the future of healthcare, both in Vietnam and globally.
MALARIA - Pharm D III year Therap .pptxAyesha Fatima
油
Malaria is a life-threatening disease. Its typically transmitted through the bite of an infected Anopheles mosquito. Infected mosquitoes carry the Plasmodium parasite. When this mosquito bites you, the parasite is released into your blood stream.
Phylum : Protozoa
Subphylum : Apicomplexa (Sporozoa)
Class : Telosporea
Genus : Plasmodium
Species : vivax
Plasmodium is one of the most harmful parasites of man.
It is a digenetic, intracellular parasite that lives in the liver cells and RBC of man. (It is extracellular in mosquito).
Its primary host is the female Anopheles mosquito and the secondary host is man. Reservoir host is monkey.
The infective stage is sickle shaped sporozoite and the mode of infection is inoculation.
Four species of Plasmodium cause four types of malaria in man.
They are
i) Plasmodium vivax benign tertian malaria
ii) Plasmodium falciparum malignant tertian malaria
iii) Plasmodium ovale mild tertian malaria
iv) Plasmodium malariae quartan malaria
Of all these four species, Plasmodium vivax is the most common and most widely distributed malaria parasite.
OBJECTIVES AND USE OF ANTIMALARIAL DRUGS
The aims of using drugs in relation to malarial infection are:
(i) To prevent clinical attack of malaria (prophylactic).
(ii) To treat clinical attack of malaria (clinical curative).
(iii) To completely eradicate the parasite from the patients body (radical curative).
(iv) To cutdown human-to-mosquito transmission (gametocidal).
These are achieved by attacking the parasite at its various stages of life cycle in the human host .
Antimalarials that act on erythrocytic schizogony are called erythrocytic schizontocides
Antimalarials that act on pre erythrocytic as well as exoerythrocytic (P. vivax) stages in liver are called tissue schizontocides,
Antimalarials which kill gametocytes in blood are called gametocides.
Severe and complicated falciparum malaria
This includes P. falciparum infection attended by any one or more of
Hyperparasitaemia,
Hyperpyrexia,
Fluid and electrolyte imbalance,
Acidosis,
Hypoglycaemia,
Prostration,
Cardiovascular collapse,
Jaundice,
Severe anaemia,
Spontaneous bleeding,
Pulmonary edema,
Haemoglobinuria,
Black water fever,
Renal failure
Cerebral malaria.
Artesunate: 2.4 mg/kg i.v. or i.m., followed by 2.4 mg/kg after 12 and 24 hours, and then once daily for 7 days. Switchover to 3 day oral ACT in between whenever the patient can take and tolerate oral medication.
or
Artemether: 3.2 mg/kg i.m. on the 1st day, followed by 1.6 mg/kg daily for 7 days. Switchover to 3 day oral ACT in between whenever the patient is able to take oral medication.
or
Arteether: 3.2 mg/kg i.m. on the 1st day, followed by 1.6 mg/kg daily for the next 4 days. Switchover to 3 day oral ACT inbetween whenever the patient is able to take oral medication.
or
Quinine diHCI: 20 mg/kg (loading dose) diluted in 10 ml/kg 5% dextrose/dextrose-saline and infused i.v. over 4 hours, followed by 10 mg/kg.
Tran Quoc Bao: The Visionary Healthcare Leader Redefining Industry StandardsIgnite Capital
油
Tran Quoc Bao is a name that resonates powerfully within the healthcare industry, known not only for his leadership but also for his ability to harness the power of social media to drive change. As the Best and Most Influential Healthcare Leader in Vietnam, Baos career is a testament to the idea that innovation and compassion can coexist in the healthcare sector, creating lasting impact for both businesses and patients alike.
With a Social Selling Index (SSI) of 60 on LinkedIn, Bao demonstrates a mastery of digital engagement that sets him apart in an industry often slow to adopt change. His score, a reflection of his strong personal brand, is not just about numbersit represents a deeper commitment to connecting with others, building meaningful relationships, and leveraging those relationships to drive real-world results. In an age where online networking is key to success, Bao has made social selling a cornerstone of his leadership approach.
His journey began with a passion for improving healthcare systems and a deep desire to help those in need. Over the years, he built a reputation as someone who combines sharp business acumen with a profound understanding of patient care. But it wasnt just about providing exceptional servicesit was about making healthcare accessible and sustainable for the communities he served. Baos innovative solutions have made a significant difference in countless lives, and his forward-thinking strategies have reshaped the way healthcare leaders engage with both their teams and their patients.
What makes Bao particularly influential is his ability to engage authentically with a global audience. His LinkedIn presence is not just filled with industry insights but also genuine discussions on leadership, technology, and human-centered care. Baos influence is growing exponentially, showing that in todays world, leadership is as much about connection as it is about expertise.
Tran Quoc Bao is more than just a healthcare leader. He is a trailblazer, a digital strategist, and, most importantly, a catalyst for change in an industry that desperately needs it. His story is one of determination, vision, and the power of meaningful connections.
Choosing the Right NDIS Support Coordinator: Key Factors & Expert Tips.Fitnall1
油
Finding the right NDIS support coordinator is essential for maximizing your plan and accessing the best services. This presentation outlines the key factors to consider, including experience, communication, independence, and local knowledge. Learn where to search, the critical questions to ask, and how to make the best choice for your needs.
MAAENT
PGDEI 101.
PAPER I: NEUROBIOLOGY
OBJECTIVES:-
1. To understand the biological basis of developmental disabilities.
2. To identify the causes and risk factors, developmental disabilities and understanding their implication on development and their prevention aspects of disability.
3. To have knowledge the early indication of brain insult and characteristic features of developmental disabilities for early identification.
UNIT I-Anatomy, Physiology and embryology
Gross anatomy of Central nervous system (Frontal, Parietal, temporal, occipital, basal ganglia, cerebellum, midbrain, Pons, medulla oblongata, autonomic nervous system, limbic system, spinal cord, spinal arc, nervous system pathways). peripheral nervous system, autonomic nervous system
Micro anatomy-Cell structure, development and function
Physiology- Neurons, synapses, transmission, Specific areas and functions-Frontal, Parietal, temporal, occipital, basal ganglia, cerebellum, midbrain, pons, medulla oblongata, autonomic nervous system, limbic system, spinal cord, spinal arc, nervous system pathways, and centers and pathways
Embryology-Stages of development
Maturation-Myelination, organization of brain, cortical sub cortical relay system
680128_Spiritual H and Complete Well-being.pptxPattie Pattie
油
Spiritual Health and Complete Well-being, Vicharn Panich, MD
Chairman of PMAC Organizing Committee
Introductory Remark in PMAC 2025 Side Meeting Complete Well-being in the Age of AI: The Crucial Role of Spiritual Health and Practical Strategies, 28 January 2025, Centara Grand Hotel, Bangkok
Diseases of Cardiovascular system .docxAyesha Fatima
油
DISORDERS OF CARDIOVASCULAR SYSTEM
HYPERTENSION
1. Hypertension is defined as persistently elevated arterial blood pressure (BP).
2. Hypertension, also known as high blood pressure, is a chronic medical condition in which the force of blood against the artery walls is consistently too high, increasing the risk of heart disease, stroke, and other health complications.
3. WHO Definition of Hypertension
a. According to the World Health Organization (WHO), hypertension is defined as:
Systolic Blood Pressure (SBP) 140 mmHg
Diastolic Blood Pressure (DBP) 90 mmHg
b. Based on repeated measurements under standardized conditions.
Risk factors
Obesity A sedentary lifestyle
Diabetes mellitus High intakes of salt or alcohol
Family history Stress
Cigarette smoking Low birth weight
Hypertension is described as essential (primary, idiopathic) or secondary to other diseases.
Irrespective of the cause, hypertension commonly affects the kidneys.
Essential hypertension
1. A condition of persistently elevated blood pressure without a known secondary cause, often associated with genetic predisposition and lifestyle factors.
Benign (chronic) hypertension
1. The rise in blood pressure is usually slight to moderate and continues to rise slowly over many years.
2. Sometimes complications, such as heart failure, cerebrovascular accident or myocardial infarction are the first indication of hypertension, but often the condition is symptomless and is only discovered during a routine examination.
Malignant (accelerated) hypertension
1. This is a rapid and aggressive acceleration of hypertensive disease.
2. Diastolic pressure in excess of 120 mmHg is common.
3. The effects are serious and quickly become apparent, e.g. haemorrhages into the retina, papilloedema (oedema around the optic disc), encephalopathy (cerebral oedema) and progressive renal disease, leading to cardiac failure.
Secondary hypertension
Hypertension resulting from other diseases accounts for 5% of all cases.
I. Kidney disease
Raised blood pressure is a complication of many kidney diseases. In kidney disease, there is salt and water retention, sometimes with excessive renin activity.
II. Endocrine disorders
a) Adrenal cortex
Secretion of excess aldosterone and cortisol stimulates the retention of excess sodium and water by the kidneys, raising the blood volume and pressure.
b) Adrenal medulla
Secretion of excess adrenaline (epinephrine) and noradrenaline (norepinephrine) raises blood pressure, e.g. phaeochromocytoma .
III. Stricture of the aorta
Hypertension develops in branching arteries proximal to the site of a stricture, e.g congenital
coarctation.
IV. Drug treatment
Hypertension may be a side-effect of some drugs, e.g. corticosteroids and oral contraceptives.
Effects and complications of hypertension
The effects of long-standing and progressively rising blood pressure are serious.
Hypertension predisposes to atherosclerosis and has specific effects on particular organs.
Heart
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2. Definition
AMPUTATION: Cutting of the extremity or part of the extremity
through the bone.
While.......
DISARTICULATION: Cutting of the extremity or part of the
extremity through the joint.
The word amputation is derived from the Latin word amputare,
"to cut away"
Should not be viewed as a failure of treatment but as the first
step in Rehabilitation.
Should be performed by the most experienced surgeon in team
3. Amputation history
*Cave-wall hand imprints have been found which demonstrate that Neolithic humans
had amputated limbs.
* Earliest literature discussing amputation is the Babylonian code of Hammurabi 1700
BC
*385 BC - Plato's symposium and Hippocrates De Articularis
*1st century BC - cautery was used for large vessels
*1588 - William Clove - first successful AKA
*1674 - Morel - battle of Borodino tourniquet
*1679 - Younge - local flaps for wound closure (animal bladder used previously)
*1781 - John Warren - 1st successful shoulder amputation
*1806 - Walter Brashear -1st successful hip joint amputation
*1825 - Nathan Smith described knee disarticulation
* 1870 - Stockes and Grittis procedure
* 1890 - Jaboulay and Girard - 1st successful hindquarter amputation
*1943 - Norman Kirk - guillotine procedure in WWII
4. Earliest amputation were done on
unanesthetized patients & haemostasis
attained by crushing or dipping the open
stump in boiling oil.
Hippocrates was the first to use ligatures.
Morel's introduced tourniquet in 1674
Lister's introduced antiseptic technique in
reducing mortality