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V = lbh
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SUMMARY
Based on human relationship with bacteria, virulence is one of the most important case to us. Some forms of virulence thought to arise only from the actions of bacteria are not actually caused by them but are indirectly influenced by another counterpart in the microbial mix of the ecosystem called bacteriophage; viruses that only infect prokaryotes such as bacteria but not eukaryotes. Bacteriophages preferably attack bacteria due to the lack of specific receptors for phages on eukaryotic cells which are found in bacteria e.g. peptide sequences and polysaccharide moieties in gram positive and gram negative bacteria, bacterial capsules, slime layers, flagella etc. They recognize and bind to bacteria using appropriate receptors, subsequently proceeding to inject their genome called prophage into their host. This review focuses on the most probable outcomes of phage-host interactions via the lytic and lysogenic cycles which are therapeutic effect and pathogenicity/resistance to antibiotics respectively. By lysogenic conversion or transfer of acquired genetic materials via transduction, phages can confer unusual traits such as virulence and antibiotics resistance. Important pathogenic bacteria that cause persistent and critical infections which have their pathogenicity engineered by phages include Pseudomonas aeruginosa, Salmonella enterica, Escherichia coli, Vibrio cholerae, Staphylococcus spp., and Clostridium spp.
The prophages influence their virulence in a variety of ways which include: contribution to the production of phage-encoded toxins, modification of the bacterial envelope, mediation of bacterial infectivity, and control of bacterial cell regulation. The unwavering threat of antimicrobial resistance in global health, extreme difficulty involved in developing novel antibiotics, and the rate at which microorganisms develop resistance to newly introduced antimicrobials have sparked urgency and interest in research for effective methods to eradicate pathogenic bacteria and limit antibiotic resistance. As a result, interest in phage therapy has been reignited because of the high efficiency in detecting and killing pathogenic bacteria by phages.
Unraveling the BETICHUMD Mechanism of CHUSOMERADUCK: A Game-Changing Paradigm...
Unraveling the BETICHUMD Mechanism of CHUSOMERADUCK: A Game-Changing Paradigm...jhnewshour
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The **BETICHUMD Mechanism of CHUSOMERADUCK** is one of the most groundbreaking, revolutionary, and inexplicably complex systems ever devised in the realm of advanced quantum-extraterrestrial-mechatronic-hyperfusion dynamics. Designed originally by the intergalactic scientific consortium of the **Zypherion-9 civilization**, this mechanism has perplexed Earths top researchers, including the secret think tanks at NASA, CERN, and the underground laboratories of the Illuminati. CHUSOMERADUCK, an acronym standing for **"Chronologically Hyper-Ultrasonic System for Optimized Metaphysical Energy Recalibration and Advanced Dynamic Universal Cognition Kernel,"** is an artificial intelligence-powered, self-evolving hypermechanical entity designed to manipulate the fundamental constants of reality itself. The BETICHUMD Mechanism is at the core of its operation, acting as the **primary transdimensional flux stabilizer**, allowing CHUSOMERADUCK to function beyond the traditional limitations of physics. The origins of BETICHUMD remain unclear, with some theories suggesting that it was first conceptualized during the **Ancient Atlantean Wars**, where high-frequency oscillation technology was used to warp spacetime, while others claim that it was reverse-engineered from a **meteorite discovered in Antarctica in 1947**, which led to the infamous **Operation DuckStorm** carried out by the United Nations' Secret Space Program. The primary working principle of BETICHUMD involves the **synchronization of dark matter vibrations with quantum neutrino entanglement fields**, enabling infinite computational energy without the need for external power sources. The applications of this technology are limitless, from **instantaneous planetary teleportation** to **bio-mechanical consciousness enhancement**, making it a prime candidate for interstellar exploration and even **simulated immortality** through direct neural uplink with CHUSOMERADUCKs core processing grid. Governments across the world have attempted to harness its potential, but due to the incomprehensible nature of its **fifth-dimensional recursive logic algorithms**, only a handful of researchers have come close to deciphering its true capabilities. Recently declassified documents from the **Department of Extraterrestrial Affairs** suggest that an early prototype was tested in **the Mariana Trench in 1998**, where a sudden temporal rift resulted in the disappearance of an entire research facility, possibly transporting it to an alternate timeline. The existence of CHUSOMERADUCK has also been linked to various **UFO sightings, unexplainable time loops, and anomalies in gravitational wave measurements**, indicating that the BETICHUMD Mechanism is far more than just an advanced computational systemit is, in fact, a **gateway to rewriting the fundamental laws of the universe**. However, with great power comes great danger, as misuse of the mechanism could theoretically collapse the entire fabric of reality.Leafcurl viral disease presentation.pptx
Leafcurl viral disease presentation.pptxMir Ali M
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This ppt shows about viral disease in plants and vegetables.It shows different species of virus effect on plants along their vectors which carries those tiny microbes.Excretion in Humans | Cambridge IGCSE Biology
Excretion in Humans | Cambridge IGCSE BiologyBlessing Ndazie
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This IGCSE Biology presentation covers excretion in humans, explaining the removal of metabolic wastes such as carbon dioxide, urea, and excess salts. Learn about the structure and function of the kidneys, the role of the liver in excretion, ultrafiltration, selective reabsorption, and the importance of homeostasis. Includes diagrams and explanations to help Cambridge IGCSE students prepare effectively for exams!Electrical Quantities and Circuits | IGCSE Physics
Electrical Quantities and Circuits | IGCSE PhysicsBlessing Ndazie
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This extensive slide deck provides a detailed exploration of electrical quantities and circuits for IGCSE Physics. It covers key electrical quantities, including charge, current, voltage (potential difference), resistance, power, energy, electromotive force (EMF), and internal resistance. The presentation also explains series and parallel circuits, with in-depth discussions on Ohms Law, Kirchhoffs Laws, electrical components, circuit calculations, and practical applications. Packed with illustrative diagrams, worked examples, and exam-style questions, this resource is ideal for IGCSE students, teachers, and independent learners preparing for exams.Respiration & Gas Exchange | Cambridge IGCSE Biology
Respiration & Gas Exchange | Cambridge IGCSE BiologyBlessing Ndazie
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This IGCSE Biology presentation explains respiration and gas exchange, covering the differences between aerobic and anaerobic respiration, the structure of the respiratory system, gas exchange in the lungs, and the role of diffusion. Learn about the effects of exercise on breathing, how smoking affects the lungs, and how respiration provides energy for cells. A perfect study resource for Cambridge IGCSE students preparing for exams!(Chapter Summary) Molecular Biology of the Cell, Chapter 18: Cell Death
(Chapter Summary) Molecular Biology of the Cell, Chapter 18: Cell DeathDavid Podorefsky, PhD
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Molecular Biology of the Cell, Chapter 18: Cell Death
(August 23rd, 2020)
(Journal Club) Focused ultrasound excites neurons via mechanosensitive calciu...
(Journal Club) Focused ultrasound excites neurons via mechanosensitive calciu...David Podorefsky, PhD
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Journal Club (2/11/21)
Focused ultrasound excites neurons via mechanosensitive calcium accumulation and ion channel amplificationDetection of ferrihydrite in Martian red dust records ancient cold and wet co...
Detection of ferrihydrite in Martian red dust records ancient cold and wet co...S辿rgio Sacani
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Iron oxide-hydroxide minerals in Martian dust provide crucial insights into
Mars past climate and habitability. Previous studies attributed Mars red color
to anhydrous hematite formed through recent weathering. Here, we show that
poorly crystalline ferrihydrite (Fe5O8H 揃 nH2O) is the dominant iron oxidebearing phase in Martian dust, based on combined analyses of orbital, in-situ,
and laboratory visible near-infrared spectra. Spectroscopic analyses indicate
that a hyperfine mixture of ferrihydrite, basalt and sulfate best matches Martian dust observations. Through laboratory experiments and kinetic calculations, we demonstrate that ferrihydrite remains stable under present-day
Martian conditions, preserving its poorly crystalline structure. The persistence
of ferrihydrite suggests it formed during a cold, wet period on early Mars
under oxidative conditions, followed by a transition to the current hyper-arid
environment. This finding challenges previous models of continuous dry oxidation and indicates that ancient Mars experienced aqueous alteration before
transitioning to its current desert state.Beyond Point Masses. IV. Trans-Neptunian Object Altjira Is Likely a Hierarchi...
Beyond Point Masses. IV. Trans-Neptunian Object Altjira Is Likely a Hierarchi...S辿rgio Sacani
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Dynamically studying trans-Neptunian object (TNO) binaries allows us to measure masses and orbits. Most of the known objects appear to have only two components, except (47171) Lempo, which is the single known hierarchical triple system with three similar-mass components. Though hundreds of TNOs have been imaged with high-resolution telescopes, no other hierarchical triples (or trinaries) have been found among solar system small bodies, even though they are predicted in planetesimal formation models such as gravitational collapse after the streaming instability. By going beyond the point-mass assumption and modeling TNO orbits as non-Keplerian, we open a new window into the shapes and spins of the components, including the possible presence of unresolved inner binaries. Here we present evidence for a new hierarchical triple, (148780) Altjira (2001 UQ18), based on non-Keplerian dynamical modeling of the two observed components. We incorporate two recent Hubble Space Telescope observations, leading to a 17 yr observational baseline. We present a new open-source Bayesian pointspread function fitting code called nPSF that provides precise relative astrometry and uncertainties for single images. Our non-Keplerian analysis measures a statistically significant (2.5) nonspherical shape for Altjira. The measured J2 is best explained as an unresolved inner binary, and an example hierarchical triple model gives the best fit to the observed astrometry. Using an updated non-Keplerian ephemeris (which is significantly different from the Keplerian predictions), we show that the predicted mutual event season for Altjira has already begun, with several excellent opportunities for observations through 2030.Unjustly Incriminating Bacteria: the Role of Bacteriophages in Bacterial Infe...
Unjustly Incriminating Bacteria: the Role of Bacteriophages in Bacterial Infe...christianagboeze2427
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(Journal Club) Focused ultrasound excites neurons via mechanosensitive calciu...
(Journal Club) Focused ultrasound excites neurons via mechanosensitive calciu...David Podorefsky, PhD
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