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Synthesis of heam 20 21

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Heme is an iron-containing porphyrin that is essential for hemoglobin function. Porphyrins are cyclic compounds formed from four pyrrole rings linked by methylene bridges that can bind metal ions. Heme synthesis primarily occurs in erythroid precursor cells in the bone marrow and liver cells, involving multiple enzymatic steps to convert the precursor uroporphyriinogen to protoporphyrin and insert iron.

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Synthesis of Heme Maria Gul
Porphyrins are cyclic compounds formed by the linkage of four pyrrole rings through methyne (=HC) bridges. A characteristic property of the porphyrins is the formation of complexes with metal ions bound to the nitrogen atom of the pyrrole rings. Examples are the iron porphyrins such as heme of hemoglobin and the magnesium-containing porphyrin chlorophyll, the photosynthetic pigment of plants. approximately 85% of heme synthesis occurs in erythroid precursor cells in the bone marrow and the majority of the remainder in hepatocytes.
Synthesis of heam 20 21
Synthesis of heam 20 21
Synthesis of heam 20 21
Uroporphyri inogen1 or hydroxy methylbilane synthase
Synthesis of heam 20 21
Synthesis of heam 20 21
Synthesis of heam 20 21

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Synthesis of heam 20 21

  • 2. Porphyrins are cyclic compounds formed by the linkage of four pyrrole rings through methyne (=HC) bridges. A characteristic property of the porphyrins is the formation of complexes with metal ions bound to the nitrogen atom of the pyrrole rings. Examples are the iron porphyrins such as heme of hemoglobin and the magnesium-containing porphyrin chlorophyll, the photosynthetic pigment of plants. approximately 85% of heme synthesis occurs in erythroid precursor cells in the bone marrow and the majority of the remainder in hepatocytes.