The document summarizes key concepts about the endocrine, nervous, and reproductive systems. It describes homeostasis and feedback mechanisms, including negative and positive feedback loops. It provides details about important endocrine glands like the pituitary gland, thyroid gland, parathyroid gland, adrenal gland, and pancreas. It explains the functions of major hormones produced by these glands, such as insulin, glucagon, cortisol, estrogen, and others, and how they help regulate processes like metabolism, stress response, and reproduction.
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2. Homeostasis and Feedback Mechanisms
Homeostasis
the balance state of internal conditions despite changes
in external environment
different body systems complement one another to
create internal balance- homeostatic regulation
3. Homeostasis and Feedback Mechanisms
Endocrine Glands secrete hormones that help
regulate the activities of cells
Stimulus- any external or internal change in the
environment
External Stimulus- arises from outside the body
Internal Stimulus- originates within the body
Feedback mechanism/ feedback regulation- self-
adjusting mechanism
4. 2 Types of Feedback Mechanism
1. Negative feedback loop
- response reduces the stimulus until conditions
return to a homeostatic
state.
6. 2 Types of Feedback Mechanism
2. Positive feedback loop
- occurs when a response amplifies a
stimulus, which in turn elicits further
response.
8. Homeostasis and Feedback Mechanisms
Neuroendocrine System- endocrine + nervous
system
Hypothalamus- contains neurosecretory cells, sends
hormones.
9. Target cells
Blood facilitates the circulation of hormones.
Hormones are recognized by their target cells via
membrane receptors
Molecular shape of the hormone should physically fit
the target cells receptor so that the hormone
receptor complex can initiate the response.
11. The Endocrine System
chemical messengers (hormones)
2 types of glands
Endocrine glands
- Release their hormones directly into the
bloodstream
Exocrine glands
- Release their secretion through ducts
13. Pituitary Gland and Hypothalamus
Produce hormones and controls various glands
close to the hypothalamus and is connected to the
blood vessels and nerves
Master Gland
Composed of the anterior and posterior lobe
Posterior lobe
extension of the hypothalamus
antidiuretic hormone (ADH) & Oxytocin
15. Pituitary Gland and Hypothalamus
Antidiuretic hormone (ADH)
decreases the amount of urine exerted by the
kidneys
Oxytocin
promote milk letdown
16. Pituitary Gland and Hypothalamus
Anterior lobe
Secretes rolactin, gonadotropic hormones, thyroid-
stimulating hormone (TSH) and growth hormones.
17. Thyroid Gland
located at the base of the neck
thyroxine is converted into triiodothyronine,
the active form of thyroid hormone
Calcitonin- lowers calcium levels
Hypothyroidism- underactive thyroid gland,
decreases metabolic rate
- radioactive iodine treatment
19. Thyroid Gland
Cretinism- physical and mental retardation
Goiter- abnormal enlargement of the thyroid
gland
Levothyroxine- a thyroid hormone
20. Parathyroid Gland
at the back of the thyroid gland
Parathormones
regulate calcium in the blood and oppose the
action of calcitonin
Enhance calcium absorption
Calcium ( muscle contraction, blood clotting and
others)
21. Adrenal Gland
above the kidney
inner part (adrenal medulla)
outer part (adrenal cortex)
22. Adrenal Medulla
epinephrine ( adrenaline) and norepinephrine
(norepinephrine)
helps the body to respond to emergencies.
Adrenaline emergency hormones
23. Adrenal Cortex
glucocorticoids, mineralocorticoids and sex
hormones
First two, prolonged stress and mobilizing energy
reserves.
Cortisol- helps body respond to stress.
Aldosterone- regulates salt and water in the
body.
24. Pancreas
located between the spleen and small intestine.
produces digestive enzymes and hormones
Islets of Langerhans- produce pancreatic amylase
secrete insulin, glucagon and somatostatin
Insulin- lowers blood sugar level
Glucagon rises blood sugar level
Somatostatin- inhibits secretion of other hormones