This document summarizes two upcoming cardiovascular trials to be presented at the ESC 2023 Congress. The STOP DAPT-3 trial will compare P2Y12 inhibitor monotherapy with dual antiplatelet therapy after PCI and found monotherapy is not superior due to higher rates of ischemic events. The FIRE trial found complete revascularization guided by full physiology to lower complications compared to culprit-only PCI in myocardial infarction patients. Both trials provide new insights into antiplatelet regimens and revascularization strategies after cardiovascular procedures.
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Trials in Cardiology.pptx
1. Ground Breaking Trials in Cardiology
Presenter: Dr. AFM Azim Anwar
azimbinanwar@gmail.com
Chairperson: Dr. Md. Faisal Ibn Kabir, FCPS, MD
Assoc. Professor, Dept Of Cardiology, BSMMU.
mfi_kabir@yahoo.com
27 August,2023
22. Stop DAPT-3 trial will be published on ESC
2023
P2Y12 I monotherapy Prasugrel vs
DAPT , after PCI
In first month
Bleeding more common in DAPT
Ischemic events common in monotherapy
Overall, Monotherapy is not superior
32. FIRE TRIAL on
ESC 2023
Complete Physiology
guided
Revascularization to
lower risk of
complication, vs culprit
only PCI in MI
45. Disclaimer: All of the above information are property of their rightful
owners. I just collaborated them in a single presentation.
Dr. AFM Azim Anwar
https://www.researchgate.net/profile/Afm-Anwar
https://orcid.org/my-orcid?orcid=0000-0002-2489-5000