The document discusses advancements in autologous stem cell therapies for knee orthopaedics, emphasizing the potential of mesenchymal stem cells derived from adipose tissue to improve cartilage repair and regenerative medicine. It highlights the need for better understanding and integration of subchondral bone mechanics in the treatment of osteochondral lesions, as current methods often fall short in functional outcomes. Additionally, it presents ongoing clinical trials and comparative studies aimed at enhancing patient recovery through innovative stem cell applications and methodologies.
Autologous Mesenchymal Stem Cells in OrthopaedicsVladimir Bobic
?
The document discusses the use of autologous mesenchymal stem cells (MSCs) in orthopaedics, particularly for regenerating cartilage and bone damaged by conditions such as osteoarthritis. It highlights various treatment options, including scaffold materials and the importance of subchondral bone in cartilage repair, while emphasizing the potential of stem cell therapy to restore tissue function. Additionally, clinical trials like the Impact Study and Cartistem are mentioned, which aim to explore the safety and effectiveness of stem cell applications in treating knee cartilage lesions.
Advances in Stem Cell Therapies: Still Experimental, or Ready to Go?DrDeAndrea
?
1) A stem cell researcher in Japan claimed a major discovery by turning adult blood cells into stem cells quickly through acid exposure, but her work is under investigation.
2) Stem cell therapies are generally considered safer when using a patient's own cells, and regulations may be prohibiting doctors from trying to cure patients with autologous stem cell treatments.
3) Pharmaceutical companies could feel threatened by stem cell therapies becoming as common as drugs, representing mobile pharmacies of healing factors, within 20 years according to one scientist.
The document provides an overview of the global stem cell market, defining stem cells, their types, and their potential applications in medicine. It discusses the current state of research and development in the field, highlighting the investment landscape and market opportunities. The stem cell market is estimated to grow significantly, with North America leading but Asia rapidly advancing in research and applications.
Louisa and David Stone operate Bicycle Recycle, a program in Williamsport, PA that aims to promote cycling culture and the benefits of biking. Through their volunteer-run shop, they teach bike repair skills, redistribute donated bikes, and advocate for more bike-friendly infrastructure like lanes and racks. Their goals are to cultivate community, encourage responsibility, and make Williamsport a more livable city by strengthening urban cycling connections. While they have made progress growing local interest, more work remains to fully realize a bike-integrated community and accommodate cyclists at local events.
This document discusses using game mechanics and feedback loops to motivate desired behaviors related to email habits and responses. It outlines a 9 step process:
1. Identify specific business goals and behaviors to encourage.
2. Translate behaviors into quantifiable data that can be tracked.
3. Attach points to tracked behaviors.
4. Translate points into a periodic score and other useful information.
5. Display the score in an engaging way.
6. Create rules to translate data into helpful feedback.
7. Set challenges and rewards.
8. Add social elements for comparison to others.
9. Make the experience fun and interesting overall.
The overall aim is to use principles from game design
This document provides a notification to @PaulBradshaw about a video on an online journalism blog discussing students protesting for free education. It includes a link to the video and encourages PaulBradshaw to watch, listen, learn, see and meet regarding the topic.
The document provides an overview of trends in online media and journalism from the 1990s to present. It discusses the evolution of platforms like blogs, social media, online tools and content management systems. It also offers guidance on developing an online news operation, using multimedia, search engine optimization, learning HTML/CSS, and engaging audiences on social networks.
- Angela surveyed 50 potential customers and found that 35 were interested in her house cleaning services.
- Her target market is working women with children in school who want cleaning done 1-2 times per month.
- Based on the surveys, Angela could earn over $4,000 per month cleaning houses 1-2 times for working mothers.
Aliens are a common element in many works of science fiction. They are typically depicted as more advanced lifeforms from other planets that are either hostile invaders or peaceful visitors exploring Earth. Some key examples include the Cylons from Battlestar Galactica who seek to destroy humanity, and the various alien races Greg encounters through space travel in many Star Trek episodes who have diverse cultures and technologies. Aliens allow science fiction writers to reflect on humanity and ask profound questions by placing people in contact with lifeforms that are both similar and different from us.
Authorea is a platform designed for collaborative research writing in the 21st century. It addresses the challenges of traditional scientific communication methods that are rooted in outdated formats. The document poses the question of how modern scientists can innovate their practices in comparison to historical figures like Galileo.
Why smart mobility is essential to our smart futureRobert Seymour
?
The document discusses the importance of smart mobility and the need for an environment that fosters the development and management of digital services across various sectors, including government and citizens. It highlights specific smart solutions such as smart waste collection, smart tree management, climate adaptation measures, smart water monitoring, and elderly care applications, each with unique benefits and technological frameworks that enhance communication and efficiency. The conclusion emphasizes the need for intelligently designed wireless connectivity to support these services effectively.
WordPress is a free, open-source blogging platform that allows users to create and maintain blogs. Users can choose between WordPress.com, which provides free hosting and software management, or WordPress.org, which requires installing and managing the software through a third-party provider or own server. The document provides step-by-step instructions for setting up an account on WordPress.com, customizing settings and appearance, adding posts and pages, and tracking comments.
The document discusses various techniques used in documentary films to present real events and their impact on spectators. It describes common documentary conventions like using natural lighting, interviews, voiceovers, and reconstructions to appear more authentic. However, it notes that these are just conventions and the selection and construction of footage can manipulate viewers just as fiction films do. Viewers must examine how 'real' events are presented and how that might influence their perspective.
NEDRA Big Data, Big Gifts: Social Donor Management EverTrue
?
This document summarizes a presentation given by Jesse Bardo of EverTrue on using social media data from LinkedIn and Facebook to improve donor management and fundraising. Some key points include: LinkedIn contains valuable career and industry data that can help segment donors, while Facebook "Likes" are correlated with increased donation rates. Analyzing these social graphs can provide insights to prospect identification, volunteer recruitment, and other areas to potentially increase fundraising returns.
Ashley Wlodarek has worked as an Administrative Assistant for Cenovus Energy for approximately 2 years. She displays a very energetic and competent work ethic, taking on initiatives beyond her role. She is an extremely thorough worker with excellent attention to detail, and interacts effectively with staff at all levels. Her organizational skills have placed her in a position of financial trust within the organization. She readily seeks guidance when goals are unclear and takes responsibility for her work. She is a quick study who promptly masters new tasks and is willing to take on challenges.
Collaborating for Trust:Pharma, Patient Organizations, & Social Mediae-Patient Connections
?
The document discusses strategies for engaging with patients suffering from rare disorders, focusing on collaboration between pharmaceutical companies and patient organizations. Key insights emphasize the importance of creating shareworthy content, understanding patients' journeys, and optimizing relevant information to improve patient outreach. A case study demonstrates successful outcomes from targeted digital content, resulting in increased website traffic and patient registrations.
The document summarizes the results of a survey conducted in Norway to determine if implementing "23 Things" made a difference in libraries. 114 librarians responded to questions about which aspects of "23 Things" were most and least useful and what they have implemented or plan to implement. Respondents also shared their views on using Web 2.0 technologies like YouTube, blogs, and social media in libraries and the motivating and demotivating factors regarding their use. The conclusion asks whether implementing "23 Things" and Web 2.0 has made a difference in libraries before and after.
Make MarcEdit Work For You: OLC Technical Services RetreatTerry Reese
?
MarcEdit is a free open source tool for working with MARC data and other metadata formats. It allows users to break, edit, and create MARC records. It also facilitates crosswalking between MARC and other metadata schemas like MODS, EAD, and Dublin Core. The tool provides global editing functions, character conversions, templates, and integration with OCLC services for tasks like batch uploading records and managing holdings. Help is available through documentation, videos, and the MarcEdit mailing list.
The document discusses the impact of climate change on global ecosystems and human societies, highlighting the urgency of addressing greenhouse gas emissions. It outlines the potential consequences, such as increased natural disasters and biodiversity loss, if immediate action is not taken. The text emphasizes the need for international cooperation and sustainable practices to mitigate these effects.
Este documento resume la controversia en torno al uso de formocresol en odontolog¨ªa pedi¨¢trica. En 3 oraciones o menos:
Formocresol ha sido el agente de elecci¨®n para pulpotom¨ªas en dientes primarios durante d¨¦cadas debido a su efecto antibacteriano y capacidad de fijaci¨®n de tejidos. Sin embargo, existen preocupaciones sobre su toxicidad sist¨¦mica y carcinogenicidad dado que estudios recientes no han encontrado evidencia concluyente de distribuci¨®n o da?o sist¨¦mico del formaldeh¨ªdo luego de su uso. Se buscan alternativ
This document discusses Hollywood's fascination with disaster films and humanity's appetite for depictions of mass destruction. It traces the history and evolution of the disaster film genre from the silent era to modern blockbusters that employ cutting-edge visual effects to portray catastrophic events. While focused on visual spectacle, these films also attempt to explore human drama and reactions to crisis through ensemble casts dealing with impending disasters.
This document discusses using game mechanics and feedback loops to motivate desired behaviors related to email habits and responses. It outlines a 9 step process:
1. Identify specific business goals and behaviors to encourage.
2. Translate behaviors into quantifiable data that can be tracked.
3. Attach points to tracked behaviors.
4. Translate points into a periodic score and other useful information.
5. Display the score in an engaging way.
6. Create rules to translate data into helpful feedback.
7. Set challenges and rewards.
8. Add social elements for comparison to others.
9. Make the experience fun and interesting overall.
The overall aim is to use principles from game design
This document provides a notification to @PaulBradshaw about a video on an online journalism blog discussing students protesting for free education. It includes a link to the video and encourages PaulBradshaw to watch, listen, learn, see and meet regarding the topic.
The document provides an overview of trends in online media and journalism from the 1990s to present. It discusses the evolution of platforms like blogs, social media, online tools and content management systems. It also offers guidance on developing an online news operation, using multimedia, search engine optimization, learning HTML/CSS, and engaging audiences on social networks.
- Angela surveyed 50 potential customers and found that 35 were interested in her house cleaning services.
- Her target market is working women with children in school who want cleaning done 1-2 times per month.
- Based on the surveys, Angela could earn over $4,000 per month cleaning houses 1-2 times for working mothers.
Aliens are a common element in many works of science fiction. They are typically depicted as more advanced lifeforms from other planets that are either hostile invaders or peaceful visitors exploring Earth. Some key examples include the Cylons from Battlestar Galactica who seek to destroy humanity, and the various alien races Greg encounters through space travel in many Star Trek episodes who have diverse cultures and technologies. Aliens allow science fiction writers to reflect on humanity and ask profound questions by placing people in contact with lifeforms that are both similar and different from us.
Authorea is a platform designed for collaborative research writing in the 21st century. It addresses the challenges of traditional scientific communication methods that are rooted in outdated formats. The document poses the question of how modern scientists can innovate their practices in comparison to historical figures like Galileo.
Why smart mobility is essential to our smart futureRobert Seymour
?
The document discusses the importance of smart mobility and the need for an environment that fosters the development and management of digital services across various sectors, including government and citizens. It highlights specific smart solutions such as smart waste collection, smart tree management, climate adaptation measures, smart water monitoring, and elderly care applications, each with unique benefits and technological frameworks that enhance communication and efficiency. The conclusion emphasizes the need for intelligently designed wireless connectivity to support these services effectively.
WordPress is a free, open-source blogging platform that allows users to create and maintain blogs. Users can choose between WordPress.com, which provides free hosting and software management, or WordPress.org, which requires installing and managing the software through a third-party provider or own server. The document provides step-by-step instructions for setting up an account on WordPress.com, customizing settings and appearance, adding posts and pages, and tracking comments.
The document discusses various techniques used in documentary films to present real events and their impact on spectators. It describes common documentary conventions like using natural lighting, interviews, voiceovers, and reconstructions to appear more authentic. However, it notes that these are just conventions and the selection and construction of footage can manipulate viewers just as fiction films do. Viewers must examine how 'real' events are presented and how that might influence their perspective.
NEDRA Big Data, Big Gifts: Social Donor Management EverTrue
?
This document summarizes a presentation given by Jesse Bardo of EverTrue on using social media data from LinkedIn and Facebook to improve donor management and fundraising. Some key points include: LinkedIn contains valuable career and industry data that can help segment donors, while Facebook "Likes" are correlated with increased donation rates. Analyzing these social graphs can provide insights to prospect identification, volunteer recruitment, and other areas to potentially increase fundraising returns.
Ashley Wlodarek has worked as an Administrative Assistant for Cenovus Energy for approximately 2 years. She displays a very energetic and competent work ethic, taking on initiatives beyond her role. She is an extremely thorough worker with excellent attention to detail, and interacts effectively with staff at all levels. Her organizational skills have placed her in a position of financial trust within the organization. She readily seeks guidance when goals are unclear and takes responsibility for her work. She is a quick study who promptly masters new tasks and is willing to take on challenges.
Collaborating for Trust:Pharma, Patient Organizations, & Social Mediae-Patient Connections
?
The document discusses strategies for engaging with patients suffering from rare disorders, focusing on collaboration between pharmaceutical companies and patient organizations. Key insights emphasize the importance of creating shareworthy content, understanding patients' journeys, and optimizing relevant information to improve patient outreach. A case study demonstrates successful outcomes from targeted digital content, resulting in increased website traffic and patient registrations.
The document summarizes the results of a survey conducted in Norway to determine if implementing "23 Things" made a difference in libraries. 114 librarians responded to questions about which aspects of "23 Things" were most and least useful and what they have implemented or plan to implement. Respondents also shared their views on using Web 2.0 technologies like YouTube, blogs, and social media in libraries and the motivating and demotivating factors regarding their use. The conclusion asks whether implementing "23 Things" and Web 2.0 has made a difference in libraries before and after.
Make MarcEdit Work For You: OLC Technical Services RetreatTerry Reese
?
MarcEdit is a free open source tool for working with MARC data and other metadata formats. It allows users to break, edit, and create MARC records. It also facilitates crosswalking between MARC and other metadata schemas like MODS, EAD, and Dublin Core. The tool provides global editing functions, character conversions, templates, and integration with OCLC services for tasks like batch uploading records and managing holdings. Help is available through documentation, videos, and the MarcEdit mailing list.
The document discusses the impact of climate change on global ecosystems and human societies, highlighting the urgency of addressing greenhouse gas emissions. It outlines the potential consequences, such as increased natural disasters and biodiversity loss, if immediate action is not taken. The text emphasizes the need for international cooperation and sustainable practices to mitigate these effects.
Este documento resume la controversia en torno al uso de formocresol en odontolog¨ªa pedi¨¢trica. En 3 oraciones o menos:
Formocresol ha sido el agente de elecci¨®n para pulpotom¨ªas en dientes primarios durante d¨¦cadas debido a su efecto antibacteriano y capacidad de fijaci¨®n de tejidos. Sin embargo, existen preocupaciones sobre su toxicidad sist¨¦mica y carcinogenicidad dado que estudios recientes no han encontrado evidencia concluyente de distribuci¨®n o da?o sist¨¦mico del formaldeh¨ªdo luego de su uso. Se buscan alternativ
This document discusses Hollywood's fascination with disaster films and humanity's appetite for depictions of mass destruction. It traces the history and evolution of the disaster film genre from the silent era to modern blockbusters that employ cutting-edge visual effects to portray catastrophic events. While focused on visual spectacle, these films also attempt to explore human drama and reactions to crisis through ensemble casts dealing with impending disasters.
1. El documento describe el taurodontismo, una anomal¨ªa dental caracterizada por un alargamiento de la c¨¢mara pulpar y una alteraci¨®n de la morfolog¨ªa radicular, que suele pasar inadvertida.
2. El taurodontismo puede ser hereditario y est¨¢ asociado con otras anomal¨ªas dentales y s¨ªndromes que involucran defectos del ectodermo.
3. Existen varias clasificaciones del grado de taurodontismo basadas en mediciones radiogr¨¢ficas de la posici¨®n de la furca y el tama?o de la c¨¢mara pulpar.
El documento consiste en una serie de n¨²meros del 1 al 31. No se ofrecen m¨¢s detalles sobre un tema espec¨ªfico. Su contenido es puramente num¨¦rico.
Alfred Hitchcock was a famous film director known for suspense and thriller movies. He is quoted as saying that a good film is worth the cost of going out for the evening. He also likened filmmaking to eating cake rather than a slice of life. Hitchcock had a signature directorial style and said audiences would expect to find a body if he directed a film like Cinderella.
The document captures a conversation among presentation design experts discussing the shortcomings of the ºÝºÝߣShare platform, particularly its inability to effectively showcase animations and dynamic presentations. Participants express disappointment that ºÝºÝߣShare tends to reinforce poor presentation practices, resulting in static content that lacks the engagement of live presentations. The conversation highlights the importance of narration and dynamic elements in enhancing audience understanding and experience, leading to a consensus that ºÝºÝߣShare's design limitations can detract from effective communication.
The 1960s marked a dynamic era of political and cultural shifts, highlighted by the emergence of the miniskirt as a significant fashion and social symbol. James Laver's law outlines the cyclical nature of fashion, capturing the miniskirt's evolution from controversial to chic, yet it remains a persistent element in contemporary fashion despite ongoing disapproval. Today, the miniskirt continues to provoke and challenge societal norms, reflecting its enduring paradox of empowerment and vulnerability.
La pandemia de COVID-19 ha tenido un impacto significativo en la econom¨ªa mundial y las vidas de millones de personas. Muchos pa¨ªses han impuesto medidas de confinamiento que han cerrado negocios y escuelas. Aunque estas medidas han ayudado a reducir la propagaci¨®n del virus, tambi¨¦n han causado un aumento en el desempleo y problemas econ¨®micos. Se espera que la recuperaci¨®n econ¨®mica lleve tiempo a medida que los pa¨ªses reabran gradualmente y las personas vuelvan a trabajar y gastar.
La pandemia de COVID-19 ha tenido un impacto significativo en la econom¨ªa mundial y las vidas de millones de personas. Muchos pa¨ªses han impuesto medidas de confinamiento que han cerrado negocios y escuelas. Aunque estas medidas han ayudado a reducir la propagaci¨®n del virus, tambi¨¦n han causado un aumento en el desempleo y problemas econ¨®micos. Se espera que la recuperaci¨®n econ¨®mica lleve tiempo a medida que los pa¨ªses reabran gradualmente y las personas vuelvan a trabajar y gastar.
La pandemia de COVID-19 ha tenido un impacto significativo en la econom¨ªa mundial y las vidas de las personas. Muchos pa¨ªses han impuesto medidas de confinamiento que han cerrado negocios y escuelas, y han pedido a la gente que se quede en casa tanto como sea posible para frenar la propagaci¨®n del virus. A medida que los pa¨ªses comienzan a reabrir gradualmente sus econom¨ªas, existen preocupaciones sobre posibles rebrotes si las medidas de distanciamiento social se relajan demasiado r¨¢pido.
La pandemia de COVID-19 ha tenido un impacto significativo en la econom¨ªa mundial y las vidas de millones de personas. Muchos pa¨ªses han impuesto medidas de confinamiento que han cerrado negocios y escuelas. Aunque estas medidas han ayudado a reducir la propagaci¨®n del virus, tambi¨¦n han causado un aumento en el desempleo y problemas econ¨®micos. Se espera que la recuperaci¨®n econ¨®mica lleve tiempo a medida que los pa¨ªses reabran gradualmente y las personas vuelvan a trabajar y gastar.
La pandemia de COVID-19 ha tenido un impacto significativo en la econom¨ªa mundial y las vidas de las personas. Muchos pa¨ªses han impuesto medidas de confinamiento que han cerrado negocios y escuelas. Aunque estas medidas han ayudado a reducir la propagaci¨®n del virus, tambi¨¦n han causado un aumento en el desempleo y problemas econ¨®micos. Se necesitan esfuerzos coordinados a nivel mundial para desarrollar tratamientos y vacunas contra el virus, y para reconstruir las econom¨ªas a medida que la pandemia disminuya.
Olivia Mitchell argumenta que estamos en medio de una revoluci¨®n del slideware a medida que las personas adoptan las ideas de pensadores como Cliff Atkison, Garr Reynolds y Nancy Duarte. Sin embargo, se?ala que esta revoluci¨®n a¨²n no se ha completado. Seg¨²n expertos como Edward Tufte, PowerPoint tiene problemas como promover presentaciones con poca sustancia y hacer que las personas piensen menos. A¨²n queda trabajo por hacer para lograr presentaciones visuales efectivas.
Seg¨²n Olivia Mitchell, estamos en una revoluci¨®n del slideware que va m¨¢s all¨¢ de lo digital hacia la era de la audiencia, donde los presentadores adoptan ideas como involucrar m¨¢s a la audiencia. Sin embargo, la verdadera revoluci¨®n a¨²n no ha ocurrido y las presentaciones siguen dependiendo en exceso de diapositivas. Los expertos critican a PowerPoint por promover presentaciones poco pensadas y dise?adas. Una comunicaci¨®n efectiva requiere de un dise?o visual cuidadoso y de involucrar a la audiencia, m¨¢s que de usar diapositivas de forma autom
The document presents a collection of humorous quotes about the brain from various notable figures, highlighting its complexities and various perceptions. It includes insights into gender differences, brain health, and the interplay of intelligence and emotion, all delivered with a comedic tone. Topics range from the absurdity of certain thoughts on the brain to reflections on its everyday use and significance in life.
This document discusses the importance of compassion for all living creatures according to many notable figures from history. It contains quotes emphasizing that animals can suffer just like humans, that cruelty to animals indicates a lack of nobility or morality in humans, and advocating for kindness and respect towards all life.