This document provides an overview of amenorrhea, including:
1. Definitions of primary and secondary amenorrhea and classifications based on cause and presentation.
2. Requirements for normal menstruation including a coordinated neuroendocrine axis and patent reproductive tract.
3. Causes of pathological amenorrhea including hypothalamic-pituitary disorders, gonadal dysgenesis, weight changes, and structural abnormalities of the reproductive tract.
Gestational trophoblastic neoplasia (GTN) is a spectrum of diseases caused by abnormal proliferation of trophoblastic tissue. It includes complete and partial hydatidiform moles, invasive moles, choriocarcinoma, placental site trophoblastic tumor, and epithelioid trophoblastic tumor. Choriocarcinoma is a malignant form that can develop from any type of pregnancy and has a high risk of metastasis. Diagnosis involves elevated hCG levels, imaging, and histopathology. Treatment depends on the type and severity but may include suction dilation and curettage, chemotherapy, and radiation therapy.
Vulvar cancer accounts for about 5% of cancers of the female genital system in the US. Possible signs include bleeding, itching, lumps or growths on the vulva, skin color changes, or ulcers. Risk factors include HPV infection, smoking, and precancerous skin conditions. Treatment depends on stage but may involve surgery to remove the tumor and nearby lymph nodes, radiation therapy, or chemoradiation. Side effects can include skin irritation in the vulvar area, as well as urinary and bowel issues. Overall survival rates vary from over 80% for local stage to under 20% for distant stage disease.
旅凌劉了侶 . 凌凌了溜隆侶, 竜旅虜僚旅侶 僚 僚凌亮亮略僚 虜留旅 侶 隆竜僚凌亮侶, 2016. 離竜侶凌粒留旅留 凌亮.13, 竜.3, 竜了. 111-118
ACOG, Uterine Fibroids. Gynecologic Problems, 2018 (Greek Version: 留亮略旅留 .)
ACOG, Uterine Fibroids - Frequently Asked Questions: Gynecologic Problems, December 2018
Aymara Mas et al., Updated approaches for management of uterine fibroids. Int J Womens Health. 2017; 9: 607617. Published online 2017 Sep 5. doi: 10.2147/IJWH.S138982. PMCID: PMC5592915, PMID: 28919823
Hee Joong Lee, MD, et al., Contemporary Management of Fibroids in Pregnancy. Rev Obstet Gynecol. 2010 Winter; 3(1): 2027. PMCID: PMC2876319. PMID: 20508779
Ioannis K Thanasas, Maria Boursiani, Rare Localizations of Genital Leiomyomas in Womans System, October 2015. ACHAIKI IATRIKI Volume 34, Issue 2
Jessica Shields, D.O., Can uterine fibroids harm my pregnancy?, March 31, 2020
Li H, Du J, Jin L, Shi Z, Liu M. Myomectomy during cesarean section. Acta Obstet Gynecol Scand 2009, 88:183-6.
Sharma JB, Kumar S, Rahman SM, Roy KK, Malhotra N. Non-puerperal incomplete uterine inversion due to large sub-mucous fundal fibroid found at hysterectomy: a report of two cases. Arch Gynecol Obstet 2009, 279:565-7.
WebMD, Uterine Fibroids and Pregnancy: How UF Affects Pregnancy. www.webmd.com
This document discusses fibroids, which are benign growths in the uterus. It notes that fibroids are very common, affecting up to 40% of women, and are more common and symptomatic in black women. While the exact causes are unknown, fibroids develop from the muscle cells of the uterus. The symptoms depend on the location, number, and size of fibroids. Treatment options include medication to manage symptoms, uterine artery embolization to reduce fibroids, and surgical options like myomectomy and hysteroscopic myomectomy to remove fibroids.
Colposcopy is a procedure that magnifies and illuminates the cervix, vagina, and vulva to examine them for abnormalities. It is usually performed when a Pap smear is abnormal or the cervix looks abnormal. During colposcopy, acetic acid is applied to help identify abnormal areas, which appear white. Biopsies may be taken of abnormal areas for further examination. Interpretation involves examining features like acetowhitening, vascular patterns, and iodine uptake to assess the severity of cervical lesions and guide treatment. Colposcopy allows close examination of the cervix to diagnose conditions like cervical intraepithelial neoplasia or condyloma.
This document discusses the management of adnexal masses through either laparoscopy or laparotomy. It notes that 5-10% of women will undergo surgery for a suspicious adnexal mass in their lifetime, with 13-21% found to be malignant. The document outlines factors for diagnosing adnexal masses, including patient history, symptoms, imaging findings, and tumor markers. It also reviews criteria for determining a surgical approach, noting the benefits of laparoscopy such as less adhesions, fewer complications, shorter recovery time, and lower costs compared to laparotomy.
Endometriosis is characterized by the presence of endometrial tissue outside the uterus, commonly causing pelvic pain and infertility. It is a progressive disease that is diagnosed via laparoscopy. Treatment options include hormone therapy, surgery, or a combination, with the goal of relieving symptoms and potentially improving fertility. Recurrence rates after surgery are estimated to be around 19% after 5 years but are lower with more extensive surgical intervention such as oophorectomy.
- Fibroids are benign smooth muscle tumors that arise from the uterus. They are very common, affecting 20-30% of women.
- Symptoms include heavy menstrual bleeding, pelvic pressure, pain, and infertility. Fibroids can range in size from small to very large masses.
- Diagnosis is usually made through ultrasound imaging. Surgical treatment options include myomectomy to remove fibroids or hysterectomy for multiple or large fibroids. Conservative management is also an option for small asymptomatic fibroids.
Uterine fibroids by oouth unit b medical students o&gTolulope Balogun
油
Mrs. AA is a 42 year old woman presenting with a large abdominal mass but no heavy bleeding symptoms. Examination and ultrasound reveal two large fibroids. Uterine fibroids are benign muscle cell tumors that are very common among women over 25, especially African women. They can cause heavy periods, abdominal pain or pressure, and infertility. Treatment options depend on symptoms and fertility desires, and include medical management to shrink fibroids, myomectomy or hysterectomy for surgical removal, or uterine artery embolization.
Fibroid uterus in detail ..... odstetrics and gynecolgyVishnu Ambareesh
油
Fibroids are benign tumors that occur in the uterus and are quite common, affecting approximately 25% of women. They develop from muscle cells in the uterus and can vary in size and location. The most common symptoms are abnormal uterine bleeding and pain. Clinical examination often reveals an enlarged, irregular uterus, and imaging tests may be used to further evaluate the size and location of any fibroids present. While usually asymptomatic, fibroids can sometimes cause complications during pregnancy like miscarriage or preterm labor, especially if they are located inside the uterine cavity.
The document discusses the internal anatomy of the uterus, defining fibroids as benign tumors arising from the smooth muscles of the uterus. It notes that fibroids are most common in women over 30 and in African/Caribbean women. Symptoms include abnormal uterine bleeding, pain, and pressure effects. Ultrasound is the primary investigation. Treatment options include conservative management, medical therapy using GnRH analogues, and surgical options of myomectomy or hysterectomy depending on factors like age and desire for future fertility. Complications include degeneration, sarcomatous change, infection, and torsion. Differential diagnosis includes other pelvic masses and causes of bleeding. Pregnancy can affect fibroids and fibroids can impact pregnancy
This document discusses abnormal uterine bleeding (AUB) and provides information on evaluating and managing AUB. It introduces the PALM-COEIN classification system for causes of AUB, which categorizes causes into 9 groups based on structural vs non-structural entities. Evaluation of AUB involves medical history, physical exam, lab tests, imaging and procedures to determine the cause. Treatment depends on the cause but may include NSAIDs, antifibrinolytic agents, or danazol to reduce bleeding through various mechanisms of action.
Uterine fibroids are benign smooth muscle tumors of the uterus that are very common. They occur in around 30% of women over 30 years of age. Symptoms include heavy bleeding, pelvic pressure, pain, and infertility. Treatment options depend on symptoms and desire for future fertility, and include medical management, myomectomy (surgical removal of fibroids), hysterectomy (removal of the uterus), uterine artery embolization, and newer minimally invasive procedures such as focused ultrasound and radiofrequency ablation. Complications can arise from degenerative changes, vascular changes, inflammation, or rarely malignant changes within the fibroids.
This document provides information on diseases of the vagina and vulva. It begins with the anatomy of the vagina and vulva. It then discusses common vaginal infections and inflammations like bacterial vaginosis, yeast infections, and trichomoniasis. Diagnosis and treatment of vaginal infections is outlined. Cysts and benign conditions of the vulva and vagina are described including lichen sclerosis and lichen planus. Finally, neoplasms of the vulva like vulvar intraepithelial neoplasia and squamous cell carcinoma are discussed.
Endometriosis is a condition where endometrial tissue grows outside the uterus, most commonly on the ovaries, fallopian tubes, and pelvic peritoneum. It causes pain and infertility and is most common during reproductive years. Theories for its cause include retrograde menstruation and genetic/immunological factors. Diagnosis involves symptoms, exam, laparoscopy, and imaging. Treatment options include pain medications, hormonal therapy like combined oral contraceptives or GnRH agonists, and surgery to remove lesions. While not curable, treatment aims to control pain and improve fertility.
Obstetric fistula is an abnormal connection between the vagina and bladder or rectum caused by prolonged obstructed labor without timely medical intervention. Nigeria accounts for 40% of global fistula cases with around 20,000 new cases annually. Risk factors include poverty, early marriage, and lack of access to emergency obstetric care. Clinical presentation includes urinary or fecal incontinence. Treatment involves surgical repair once inflammation subsides, while prevention focuses on girl child education, empowerment, antenatal care, and emergency obstetric services.
This document summarizes evidence and current perspectives on breech presentation and delivery. It discusses that breech occurs in 20% of pregnancies at 28 weeks and 4% at term. Perinatal mortality is increased with breech due to factors like prematurity and birth trauma. The Term Breech Trial found increased risks with vaginal breech delivery. However, some studies have questioned the Trial's conclusions. Elective c-section is often recommended now for term breech, though trial of vaginal delivery may be safe in some select cases. The document also reviews controversies, techniques, risks of different delivery modes, and the role of external cephalic version in attempting to turn breech babies.
This document discusses gynaecologic tumours that can occur during pregnancy, including fibroids, ovarian tumours, and cervical cancer. Fibroids can cause complications during pregnancy like abortion, premature labor, and obstructed labor. Ovarian tumours risk torsion and rupture during pregnancy. Small ovarian cysts are monitored while larger or complex cysts are removed. Cervical cancers are screened for, and pre-invasive lesions may be followed until after delivery when treated. Invasive cervical cancer carries risks of preterm delivery, obstructed labor, and infection, and is typically treated with surgery or radiation after early delivery.
Endometrial hyperplasia is an increased proliferation of endometrial glands relative to the stroma that can progress to endometrial carcinoma. It occurs most often in peri-menopausal women with elevated estrogen levels and is caused by prolonged, unopposed estrogen stimulation. Endometrial hyperplasia is classified as simple, complex, or atypical depending on architectural and cytological abnormalities. Endometrial carcinoma is the most common cancer of the female reproductive system, occurring most often in post-menopausal women. It is broadly classified into Type I and Type II tumors based on clinical and molecular characteristics and risk factors. Surgery is the primary treatment for early-stage disease while radiation and chemotherapy may be used
1. Ovarian tumors are the most common medical problems affecting the ovaries and can be benign or malignant.
2. Benign ovarian tumors are more common than malignant tumors, accounting for approximately 80% of ovarian tumors. Common types of benign ovarian tumors include serous cystadenomas, mucinous cystadenomas, dermoid cysts, and Brenner tumors.
3. Malignant ovarian tumors tend to grow silently and spread widely before causing symptoms, making early detection challenging. Epithelial ovarian cancers account for about 70-80% of ovarian cancer cases.
Ovarian tumors can be either functional cysts in reproductive aged women or neoplasms. Teratomas, also known as dermoid cysts, are the most common type of germ cell tumor and contain tissues from all three germ layers. Mature teratomas typically present in younger patients as asymptomatic cysts that can be managed conservatively with ultrasound follow up. Laparoscopic cystectomy is generally a safe approach for removing dermoid cysts though there is a small risk of intraoperative cyst rupture.
This document provides information on the evaluation and management of abnormal uterine bleeding (AUB). It begins with definitions of terms and classifications of AUB. Evaluation involves a history, physical exam, and testing as needed which may include ultrasound, hysteroscopy, or endometrial biopsy to determine the cause. Causes are categorized using the FIGO PALM-COEIN system. Treatment options discussed include general measures, medical therapies like hormones, NSAIDs, tranexamic acid, and surgical procedures such as endometrial ablation or hysterectomy. Non-hormonal and hormonal medical treatments are summarized. The document concludes with a discussion of progestin therapies.
An ectopic pregnancy occurs when a fertilized egg implants and grows outside the uterus, usually in the fallopian tubes. It can be life-threatening because it may cause internal bleeding. The document discusses the definition, incidence, risk factors, types (acute, unruptured, chronic), clinical presentation, investigations, and management approaches for ectopic pregnancies, including expectant, medical, and surgical options depending on the individual case. The goal of treatment is to preserve fertility when possible through conservative approaches like salpingostomy or systemic methotrexate administration.
This document discusses rectovaginal and rectourethral fistulas. It begins by defining rectovaginal fistulas and discussing their causes, which include obstetric injuries, inflammatory bowel disease, prior surgery, and infections. It then covers the classification, presentation, examination, and diagnosis of rectovaginal fistulas. The document discusses the treatment options for rectovaginal fistulas, including medical therapy, surgical options such as local repairs via transvaginal or transanal approaches, and abdominal repairs. It provides details on techniques for local repairs like sliding flap repairs and transperineal repairs.
Definition of fibroid / uterine leiomyoma
Diagnosis of Fibroid
Treatment of uterine fibroid
Surgery for uterine fibroid
When is surrogacy required for fibroid
By Dr Gajendra Tomar, Indore Infertility Clinic, IVF center
Uterine fibroids, or leiomyomas, are benign tumors that develop from the smooth muscle cells of the uterus. They are classified based on their location within the uterus. The most common symptoms are abnormal uterine bleeding and pelvic pain or pressure. Risk factors include genetics, race, and hormone levels. Treatment options depend on symptoms and fertility desires, and include medications, surgery such as myomectomy or hysterectomy, uterine artery embolization, and other minimally invasive procedures. Fibroids often change over time through processes such as atrophy, hyaline degeneration, or red degeneration.
This document discusses tumors of the uterus, including benign and malignant tumors. It focuses on leiomyomas (uterine fibroids), which are the most common benign tumors. Leiomyomas originate from the uterine muscle and can be classified by their location. They are most often asymptomatic but can cause abnormal bleeding, pain, pressure effects, and infertility. Diagnosis involves examination, imaging studies, and ruling out other pelvic masses. Treatment options include watchful waiting, medications to control symptoms, and surgical procedures like myomectomy and hysterectomy.
Endometriosis is characterized by the presence of endometrial tissue outside the uterus, commonly causing pelvic pain and infertility. It is a progressive disease that is diagnosed via laparoscopy. Treatment options include hormone therapy, surgery, or a combination, with the goal of relieving symptoms and potentially improving fertility. Recurrence rates after surgery are estimated to be around 19% after 5 years but are lower with more extensive surgical intervention such as oophorectomy.
- Fibroids are benign smooth muscle tumors that arise from the uterus. They are very common, affecting 20-30% of women.
- Symptoms include heavy menstrual bleeding, pelvic pressure, pain, and infertility. Fibroids can range in size from small to very large masses.
- Diagnosis is usually made through ultrasound imaging. Surgical treatment options include myomectomy to remove fibroids or hysterectomy for multiple or large fibroids. Conservative management is also an option for small asymptomatic fibroids.
Uterine fibroids by oouth unit b medical students o&gTolulope Balogun
油
Mrs. AA is a 42 year old woman presenting with a large abdominal mass but no heavy bleeding symptoms. Examination and ultrasound reveal two large fibroids. Uterine fibroids are benign muscle cell tumors that are very common among women over 25, especially African women. They can cause heavy periods, abdominal pain or pressure, and infertility. Treatment options depend on symptoms and fertility desires, and include medical management to shrink fibroids, myomectomy or hysterectomy for surgical removal, or uterine artery embolization.
Fibroid uterus in detail ..... odstetrics and gynecolgyVishnu Ambareesh
油
Fibroids are benign tumors that occur in the uterus and are quite common, affecting approximately 25% of women. They develop from muscle cells in the uterus and can vary in size and location. The most common symptoms are abnormal uterine bleeding and pain. Clinical examination often reveals an enlarged, irregular uterus, and imaging tests may be used to further evaluate the size and location of any fibroids present. While usually asymptomatic, fibroids can sometimes cause complications during pregnancy like miscarriage or preterm labor, especially if they are located inside the uterine cavity.
The document discusses the internal anatomy of the uterus, defining fibroids as benign tumors arising from the smooth muscles of the uterus. It notes that fibroids are most common in women over 30 and in African/Caribbean women. Symptoms include abnormal uterine bleeding, pain, and pressure effects. Ultrasound is the primary investigation. Treatment options include conservative management, medical therapy using GnRH analogues, and surgical options of myomectomy or hysterectomy depending on factors like age and desire for future fertility. Complications include degeneration, sarcomatous change, infection, and torsion. Differential diagnosis includes other pelvic masses and causes of bleeding. Pregnancy can affect fibroids and fibroids can impact pregnancy
This document discusses abnormal uterine bleeding (AUB) and provides information on evaluating and managing AUB. It introduces the PALM-COEIN classification system for causes of AUB, which categorizes causes into 9 groups based on structural vs non-structural entities. Evaluation of AUB involves medical history, physical exam, lab tests, imaging and procedures to determine the cause. Treatment depends on the cause but may include NSAIDs, antifibrinolytic agents, or danazol to reduce bleeding through various mechanisms of action.
Uterine fibroids are benign smooth muscle tumors of the uterus that are very common. They occur in around 30% of women over 30 years of age. Symptoms include heavy bleeding, pelvic pressure, pain, and infertility. Treatment options depend on symptoms and desire for future fertility, and include medical management, myomectomy (surgical removal of fibroids), hysterectomy (removal of the uterus), uterine artery embolization, and newer minimally invasive procedures such as focused ultrasound and radiofrequency ablation. Complications can arise from degenerative changes, vascular changes, inflammation, or rarely malignant changes within the fibroids.
This document provides information on diseases of the vagina and vulva. It begins with the anatomy of the vagina and vulva. It then discusses common vaginal infections and inflammations like bacterial vaginosis, yeast infections, and trichomoniasis. Diagnosis and treatment of vaginal infections is outlined. Cysts and benign conditions of the vulva and vagina are described including lichen sclerosis and lichen planus. Finally, neoplasms of the vulva like vulvar intraepithelial neoplasia and squamous cell carcinoma are discussed.
Endometriosis is a condition where endometrial tissue grows outside the uterus, most commonly on the ovaries, fallopian tubes, and pelvic peritoneum. It causes pain and infertility and is most common during reproductive years. Theories for its cause include retrograde menstruation and genetic/immunological factors. Diagnosis involves symptoms, exam, laparoscopy, and imaging. Treatment options include pain medications, hormonal therapy like combined oral contraceptives or GnRH agonists, and surgery to remove lesions. While not curable, treatment aims to control pain and improve fertility.
Obstetric fistula is an abnormal connection between the vagina and bladder or rectum caused by prolonged obstructed labor without timely medical intervention. Nigeria accounts for 40% of global fistula cases with around 20,000 new cases annually. Risk factors include poverty, early marriage, and lack of access to emergency obstetric care. Clinical presentation includes urinary or fecal incontinence. Treatment involves surgical repair once inflammation subsides, while prevention focuses on girl child education, empowerment, antenatal care, and emergency obstetric services.
This document summarizes evidence and current perspectives on breech presentation and delivery. It discusses that breech occurs in 20% of pregnancies at 28 weeks and 4% at term. Perinatal mortality is increased with breech due to factors like prematurity and birth trauma. The Term Breech Trial found increased risks with vaginal breech delivery. However, some studies have questioned the Trial's conclusions. Elective c-section is often recommended now for term breech, though trial of vaginal delivery may be safe in some select cases. The document also reviews controversies, techniques, risks of different delivery modes, and the role of external cephalic version in attempting to turn breech babies.
This document discusses gynaecologic tumours that can occur during pregnancy, including fibroids, ovarian tumours, and cervical cancer. Fibroids can cause complications during pregnancy like abortion, premature labor, and obstructed labor. Ovarian tumours risk torsion and rupture during pregnancy. Small ovarian cysts are monitored while larger or complex cysts are removed. Cervical cancers are screened for, and pre-invasive lesions may be followed until after delivery when treated. Invasive cervical cancer carries risks of preterm delivery, obstructed labor, and infection, and is typically treated with surgery or radiation after early delivery.
Endometrial hyperplasia is an increased proliferation of endometrial glands relative to the stroma that can progress to endometrial carcinoma. It occurs most often in peri-menopausal women with elevated estrogen levels and is caused by prolonged, unopposed estrogen stimulation. Endometrial hyperplasia is classified as simple, complex, or atypical depending on architectural and cytological abnormalities. Endometrial carcinoma is the most common cancer of the female reproductive system, occurring most often in post-menopausal women. It is broadly classified into Type I and Type II tumors based on clinical and molecular characteristics and risk factors. Surgery is the primary treatment for early-stage disease while radiation and chemotherapy may be used
1. Ovarian tumors are the most common medical problems affecting the ovaries and can be benign or malignant.
2. Benign ovarian tumors are more common than malignant tumors, accounting for approximately 80% of ovarian tumors. Common types of benign ovarian tumors include serous cystadenomas, mucinous cystadenomas, dermoid cysts, and Brenner tumors.
3. Malignant ovarian tumors tend to grow silently and spread widely before causing symptoms, making early detection challenging. Epithelial ovarian cancers account for about 70-80% of ovarian cancer cases.
Ovarian tumors can be either functional cysts in reproductive aged women or neoplasms. Teratomas, also known as dermoid cysts, are the most common type of germ cell tumor and contain tissues from all three germ layers. Mature teratomas typically present in younger patients as asymptomatic cysts that can be managed conservatively with ultrasound follow up. Laparoscopic cystectomy is generally a safe approach for removing dermoid cysts though there is a small risk of intraoperative cyst rupture.
This document provides information on the evaluation and management of abnormal uterine bleeding (AUB). It begins with definitions of terms and classifications of AUB. Evaluation involves a history, physical exam, and testing as needed which may include ultrasound, hysteroscopy, or endometrial biopsy to determine the cause. Causes are categorized using the FIGO PALM-COEIN system. Treatment options discussed include general measures, medical therapies like hormones, NSAIDs, tranexamic acid, and surgical procedures such as endometrial ablation or hysterectomy. Non-hormonal and hormonal medical treatments are summarized. The document concludes with a discussion of progestin therapies.
An ectopic pregnancy occurs when a fertilized egg implants and grows outside the uterus, usually in the fallopian tubes. It can be life-threatening because it may cause internal bleeding. The document discusses the definition, incidence, risk factors, types (acute, unruptured, chronic), clinical presentation, investigations, and management approaches for ectopic pregnancies, including expectant, medical, and surgical options depending on the individual case. The goal of treatment is to preserve fertility when possible through conservative approaches like salpingostomy or systemic methotrexate administration.
This document discusses rectovaginal and rectourethral fistulas. It begins by defining rectovaginal fistulas and discussing their causes, which include obstetric injuries, inflammatory bowel disease, prior surgery, and infections. It then covers the classification, presentation, examination, and diagnosis of rectovaginal fistulas. The document discusses the treatment options for rectovaginal fistulas, including medical therapy, surgical options such as local repairs via transvaginal or transanal approaches, and abdominal repairs. It provides details on techniques for local repairs like sliding flap repairs and transperineal repairs.
Definition of fibroid / uterine leiomyoma
Diagnosis of Fibroid
Treatment of uterine fibroid
Surgery for uterine fibroid
When is surrogacy required for fibroid
By Dr Gajendra Tomar, Indore Infertility Clinic, IVF center
Uterine fibroids, or leiomyomas, are benign tumors that develop from the smooth muscle cells of the uterus. They are classified based on their location within the uterus. The most common symptoms are abnormal uterine bleeding and pelvic pain or pressure. Risk factors include genetics, race, and hormone levels. Treatment options depend on symptoms and fertility desires, and include medications, surgery such as myomectomy or hysterectomy, uterine artery embolization, and other minimally invasive procedures. Fibroids often change over time through processes such as atrophy, hyaline degeneration, or red degeneration.
This document discusses tumors of the uterus, including benign and malignant tumors. It focuses on leiomyomas (uterine fibroids), which are the most common benign tumors. Leiomyomas originate from the uterine muscle and can be classified by their location. They are most often asymptomatic but can cause abnormal bleeding, pain, pressure effects, and infertility. Diagnosis involves examination, imaging studies, and ruling out other pelvic masses. Treatment options include watchful waiting, medications to control symptoms, and surgical procedures like myomectomy and hysterectomy.
This document discusses uterine fibroids, also known as leiomyomas. It defines a fibroid as a benign smooth muscle tumor of the uterine wall. Fibroids are very common, affecting 25-50% of women. While the exact cause is unknown, estrogen is thought to play a role in growth. Fibroids can cause heavy bleeding, pain, pressure effects, and infertility. Diagnosis involves imaging like ultrasound and treatment depends on factors like age, symptoms, and desire for future pregnancy. Options include observation, medication, myomectomy (surgical removal), or hysterectomy.
This document discusses endometrial pathologies including normal endometrium, endometrial hyperplasia, epidemiology, risk factors, clinical presentation, diagnosis, classification, atypical hyperplasia, risk of cancer, endometrial cancer types and subtypes, pathology, histopathology, and presentation. It provides details on the gland-to-stroma ratio in normal and hyperplastic endometrium. It notes that endometrial hyperplasia is a precursor to type 1 endometrial cancer and lists obesity, diabetes, PCOS, and HRT as risk factors. Diagnostic tools include ultrasound, pipelle biopsy, hysteroscopy and biopsy.
The document discusses benign lesions of the uterus and endometrium. It covers several topics including uterine polyps, endometrial polyps, and fibroids. Uterine polyps can be single or multiple, pedunculated or sessile. Endometrial polyps are common benign growths that present with abnormal bleeding and are detected by ultrasound or hysteroscopy. Fibroids are the most common benign tumors of the uterus, composed of smooth muscle cells, and can cause heavy bleeding or pain.
Ovarian cancer is a malignant proliferation of ovarian cells. The most common types are serous, endometrioid, mucinous, clear cell, and undifferentiated epithelial ovarian cancers. Risk factors include increasing age, family history, BRCA gene mutations, nulliparity, infertility, and obesity. Symptoms include abdominal pain, bloating, and changes in bowel or bladder habits. Diagnosis involves imaging tests and blood markers like CA-125. Staging determines prognosis and treatment, which may include surgery, chemotherapy, and radiation. Prognosis depends on cancer type and stage, with 5-year survival rates over 90% for localized disease but only 30% for advanced stages.
Uterine fibroids are benign smooth muscle tumors that occur in the uterus. They are very common, affecting up to 30% of women over 30 years of age. Fibroids are usually asymptomatic but can cause heavy bleeding, pain, infertility, and pregnancy complications. While fibroids may enlarge during pregnancy due to increased estrogen levels, they typically shrink after menopause when estrogen levels decline. Pregnancy can also cause degenerative changes in fibroids such as red degeneration. Treatment depends on symptoms and may include medication, surgery such as myomectomy or hysterectomy, or minimally invasive procedures like uterine artery embolization.
Uterine leiomyomas, or fibroids, are benign tumors composed of smooth muscle and fibrous tissue that develop in the uterus. They are very common, affecting 20-30% of women of reproductive age. Fibroids are hormone dependent and usually shrink after menopause. They can cause heavy periods, pelvic pain or pressure, urinary issues, and pregnancy complications. Diagnosis involves physical exam, ultrasound, MRI or other imaging tests. Treatment options depend on symptoms and may include pain medications, hormone therapies, surgical procedures like myomectomy or hysterectomy, or watchful waiting.
This document discusses breast cancer, including its symptoms, risk factors, and prevention. It notes that breast cancer is the leading cancer in Indian women, but has a high survival rate if caught early. Some key symptoms include lumps, discharge from the nipple, and changes to breast skin. Major uncontrollable risk factors include age, family history, dense breast tissue, and genetics. Controllable risk factors include having children later in life, not breastfeeding, alcohol use, obesity, and lack of exercise. The document emphasizes that prevention is better than cure and encourages awareness of breast cancer.
Uterine leiomyomas, or fibroids, are benign tumors that develop in the smooth muscle of the uterus. They are very common, affecting 20-40% of women during their reproductive years. While most fibroids do not cause symptoms, the most common complaint is abnormal uterine bleeding. Treatment options include medical management to control symptoms, surgical removal of fibroids (myomectomy), or hysterectomy for women who have completed childbearing. Myomectomy aims to conserve fertility but carries risks of heavy bleeding and potential complications. Laparoscopic myomectomy is gaining popularity for select fibroid cases but closure of the uterine wall can be challenging.
Uterine fibroids are benign tumours of the uterine smooth muscle that are common and affect around 25% of women at some point in their lifetime. They are often multiple and vary in size. While fibroids are usually asymptomatic, they can cause heavy periods, pressure symptoms, pain, and infertility. Treatment options include hysterectomy, myomectomy, uterine artery embolization, and hormonal therapies like GnRH analogues. Fibroids generally do not affect pregnancy but can increase risks of bleeding and preterm delivery.
Uterine fibroids are benign tumors that arise from the smooth muscle cells of the uterus. They are the most common pelvic tumor in women. Fibroids can be classified based on their location within the uterus as submucosal, intramural, subserosal, or cervical. Symptoms depend on the size and location of fibroids and include heavy menstrual bleeding, pelvic pressure or pain, and reproductive complications like infertility. Diagnosis involves history, physical exam, pelvic ultrasound, and sometimes additional imaging like MRI.
Uterine fibroids are benign muscle tumors that are the most common pelvic tumor in women. Symptoms include heavy bleeding, pelvic pressure, and reproductive issues. Evaluation involves physical exam, ultrasound, and sometimes MRI. Treatment options include medical management, minimally invasive procedures like uterine artery embolization, and surgical options like myomectomy or hysterectomy.
Fibroids are benign smooth muscle tumors that originate from the uterus. They are very common in women of reproductive age. Fibroids can vary in size and location within the uterus. Common symptoms include heavy menstrual bleeding, pelvic pressure or pain. Treatment options depend on a woman's symptoms and desire for future fertility. Options include medication, surgical removal of fibroids (myomectomy), or complete hysterectomy. Differential diagnosis of a pelvic mass should consider other potential causes such as ovarian cysts or tumors.
How to use Init Hooks in Odoo 18 - Odoo 際際滷sCeline George
油
In this slide, well discuss on how to use Init Hooks in Odoo 18. In Odoo, Init Hooks are essential functions specified as strings in the __init__ file of a module.
APM People Interest Network Conference 2025
-Autonomy, Teams and Tension: Projects under stress
-Tim Lyons
-The neurological levels of
team-working: Harmony and tensions
With a background in projects spanning more than 40 years, Tim Lyons specialised in the delivery of large, complex, multi-disciplinary programmes for clients including Crossrail, Network Rail, ExxonMobil, Siemens and in patent development. His first career was in broadcasting, where he designed and built commercial radio station studios in Manchester, Cardiff and Bristol, also working as a presenter and programme producer. Tim now writes and presents extensively on matters relating to the human and neurological aspects of projects, including communication, ethics and coaching. He holds a Masters degree in NLP, is an NLP Master Practitioner and International Coach. He is the Deputy Lead for APMs People Interest Network.
Session | The Neurological Levels of Team-working: Harmony and Tensions
Understanding how teams really work at conscious and unconscious levels is critical to a harmonious workplace. This session uncovers what those levels are, how to use them to detect and avoid tensions and how to smooth the management of change by checking you have considered all of them.
Prelims of Kaun TALHA : a Travel, Architecture, Lifestyle, Heritage and Activism quiz, organized by Conquiztadors, the Quiz society of Sri Venkateswara College under their annual quizzing fest El Dorado 2025.
Blind Spots in AI and Formulation Science Knowledge Pyramid (Updated Perspect...Ajaz Hussain
油
This presentation delves into the systemic blind spots within pharmaceutical science and regulatory systems, emphasizing the significance of "inactive ingredients" and their influence on therapeutic equivalence. These blind spots, indicative of normalized systemic failures, go beyond mere chance occurrences and are ingrained deeply enough to compromise decision-making processes and erode trust.
Historical instances like the 1938 FD&C Act and the Generic Drug Scandals underscore how crisis-triggered reforms often fail to address the fundamental issues, perpetuating inefficiencies and hazards.
The narrative advocates a shift from reactive crisis management to proactive, adaptable systems prioritizing continuous enhancement. Key hurdles involve challenging outdated assumptions regarding bioavailability, inadequately funded research ventures, and the impact of vague language in regulatory frameworks.
The rise of large language models (LLMs) presents promising solutions, albeit with accompanying risks necessitating thorough validation and seamless integration.
Tackling these blind spots demands a holistic approach, embracing adaptive learning and a steadfast commitment to self-improvement. By nurturing curiosity, refining regulatory terminology, and judiciously harnessing new technologies, the pharmaceutical sector can progress towards better public health service delivery and ensure the safety, efficacy, and real-world impact of drug products.
Digital Tools with AI for e-Content Development.pptxDr. Sarita Anand
油
This ppt is useful for not only for B.Ed., M.Ed., M.A. (Education) or any other PG level students or Ph.D. scholars but also for the school, college and university teachers who are interested to prepare an e-content with AI for their students and others.
How to Setup WhatsApp in Odoo 17 - Odoo 際際滷sCeline George
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Integrate WhatsApp into Odoo using the WhatsApp Business API or third-party modules to enhance communication. This integration enables automated messaging and customer interaction management within Odoo 17.
QuickBooks Desktop to QuickBooks Online How to Make the MoveTechSoup
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If you use QuickBooks Desktop and are stressing about moving to QuickBooks Online, in this webinar, get your questions answered and learn tips and tricks to make the process easier for you.
Key Questions:
* When is the best time to make the shift to QuickBooks Online?
* Will my current version of QuickBooks Desktop stop working?
* I have a really old version of QuickBooks. What should I do?
* I run my payroll in QuickBooks Desktop now. How is that affected?
*Does it bring over all my historical data? Are there things that don't come over?
* What are the main differences between QuickBooks Desktop and QuickBooks Online?
* And more
Computer Application in Business (commerce)Sudar Sudar
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The main objectives
1. To introduce the concept of computer and its various parts. 2. To explain the concept of data base management system and Management information system.
3. To provide insight about networking and basics of internet
Recall various terms of computer and its part
Understand the meaning of software, operating system, programming language and its features
Comparing Data Vs Information and its management system Understanding about various concepts of management information system
Explain about networking and elements based on internet
1. Recall the various concepts relating to computer and its various parts
2 Understand the meaning of softwares, operating system etc
3 Understanding the meaning and utility of database management system
4 Evaluate the various aspects of management information system
5 Generating more ideas regarding the use of internet for business purpose
Database population in Odoo 18 - Odoo slidesCeline George
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In this slide, well discuss the database population in Odoo 18. In Odoo, performance analysis of the source code is more important. Database population is one of the methods used to analyze the performance of our code.
Mate, a short story by Kate Grenvile.pptxLiny Jenifer
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A powerpoint presentation on the short story Mate by Kate Greenville. This presentation provides information on Kate Greenville, a character list, plot summary and critical analysis of the short story.
2. INTRODUCTION
Benign tumours (leiomyomata) of uterine smooth muscle
Common 25% of women in a lifetime
The most common uterine tumor
Occurring in about 30% of women above the age of 30 years.
Occurs up to 75% of hysterectomy specimens
Symptomatic in 1/3 of cases
More common in the obese
Less common in smokers
3. Age:
30-40 years.
Rare before 30 or after 40 years
Parity:
Common in nulliparas, patients with low parity.
It is rare in multiparas.
Race:
3-9 times more common in negroids.
Family history:
Usually positive.
Hyper-estrenemia:
Estrogen receptors (ER) more than the surrounding myometrium but less than those in the
endometrium
Common in low parity.
Atrophies and shrinks after menopause.
Common association with other hyper-estrenic conditions as endometriosis, endometrial
hyperplasia and endometrial carcinoma.
4. ETIOLOGY
Genetic changes: Many fibroids contain changes in genes that
differ from those in normal uterine muscle cells.
Hormones: Estrogen and progesterone, two hormones that
stimulate development of the uterine lining during each
menstrual cycle in preparation for pregnancy, appear to
promote the growth of fibroids. Fibroids contain more estrogen
and progesterone receptors than normal uterine muscle cells
do. Fibroids tend to shrink after menopause due to a decrease
in hormone production.
Other growth factors: Substances that help the body maintain
tissues, such as insulin-like growth factor, may affect fibroid