Zinc is an essential micromineral that is present in all cells and tissues of the body. It plays important roles in growth, development, immunity, and the metabolism of protein and nucleic acids. The recommended daily allowance of zinc varies depending on age and gender. Good dietary sources include oysters, meat, poultry, eggs, dairy products, and nuts. Both zinc deficiency and toxicity can cause health issues, with deficiency linked to impaired growth and development.
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2. Normal healthy adult contains 1.5-2.5g zinc.
Present in all cells, tissues, organs, fluids and
secretions.
90% of zinc is in muscle and bone.
Blood plasma contains 0.1% zinc.
Zinc plasma level is about 96ug/100ml in adults
and 8.9ug/100ml in children.
3. Functions
Essential for normal growth, development,
reproduction and immunity.
Involved in maintaining appetite, assisting in the
perception of taste and for night vision.
Humans and animals contain about 200 enzymes
whose activity depends on the presence of zinc.
Considered as an antioxidant nutrient.
Essential for the metabolism of protein and
nucleic acids.
Maintenence and replication of DNA and RNA.
Involved in cholesterol transport and in maintainig
the stability of lipids within the cell membrane.
4. RDA
Group Zinc (mg/day)
Man 14
Woman 11
Pregnancy 12
Lactating 12
Infants -
6-12 months 2
Children
1-3 years 2.5
4-6 years 3.7
7-9 years 4.9
Boys
10-12 years 7
13-15 years 11.9
16-18 years 14.7
Girls
10-12 years 7.1
13-15 years 10.7
16-18 years 14.7
5. Sources
Zinc status of soil determines the concentration of
zinc in foods.
FAO rated India low in ratings soil for zinc
concentration.
Oysters 1mg/g
Meat, poultry, eggs and dairy products are the best
sources.
Outer layer of grains also contributes to zinc.
Nuts contain high amount of zinc.
6. Toxicity
An acute toxicity with 1-2g of zinc sulphate can
produce metallic taste, nausea, vomiting,
epigastric pain, abdominal cramps and bloody
diarrhoea.
7. Deficiency
Some of the factors of zinc deficiency are
excessive phytates and phosphates in diet,
malabsorption, hepatitis, chronic blood loss,
trauma, alcoholic liver disease, surgery, burns,
excessive sweating etc.
Acrodermatitis enteropathica Disorder of zinc
metabolism. Severe dermatitis appear in the first
few months of an infants life, when the infant is
switched from mothers milk to cows milk.
8. Premature infants and PEM (Protein Energy
Malnutrition) children are susceptible to zinc
deficiency.
The clinical manifestations include growth
retardation, male hypogonadism (a condition in
which the body doesn't produce enough of the
hormone that plays a key role in masculine
growth and development during puberty
(testosterone) or enough sperm or both) in the
adolescents, rough skin, poor appetite, mental