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Microbodies/PeroxisomeMicrobodies/Peroxisome
Presented byPresented by
Jim BernoskiJim Bernoski
StructureStructure
 A crystalline structure inside a sac which also containsA crystalline structure inside a sac which also contains
amorphous gray materialamorphous gray material
 Bound by a single membrane that separates theirBound by a single membrane that separates their
contents from the cytosol (the internal fluid of the cell)contents from the cytosol (the internal fluid of the cell)
and contain membrane proteins critical for variousand contain membrane proteins critical for various
functionsfunctions
FunctionFunction
 They participate in the metabolism of fatty acids andThey participate in the metabolism of fatty acids and
many other metabolites. Peroxisomes harbor enzymesmany other metabolites. Peroxisomes harbor enzymes
that rid the cell of toxic peroxides.that rid the cell of toxic peroxides.
 Import proteins into the organelles and aid inImport proteins into the organelles and aid in
proliferation. Peroxisomes can replicate by enlarging andproliferation. Peroxisomes can replicate by enlarging and
then dividing.then dividing.
 Peroxisomes also play a role in the production of bilePeroxisomes also play a role in the production of bile
acids and proteins.acids and proteins.
Diseases/MalfunctionDiseases/Malfunction
 Adrenoleukodystrophy- AKA Addison-Schilder DiseaseAdrenoleukodystrophy- AKA Addison-Schilder Disease
or Siemerling-Creutzfeldt Diseaseor Siemerling-Creutzfeldt Disease
 Zellweger SyndromeZellweger Syndrome (Nothing to do with Renee Zellweger)(Nothing to do with Renee Zellweger)

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Microbodies

  • 2. StructureStructure A crystalline structure inside a sac which also containsA crystalline structure inside a sac which also contains amorphous gray materialamorphous gray material Bound by a single membrane that separates theirBound by a single membrane that separates their contents from the cytosol (the internal fluid of the cell)contents from the cytosol (the internal fluid of the cell) and contain membrane proteins critical for variousand contain membrane proteins critical for various functionsfunctions
  • 3. FunctionFunction They participate in the metabolism of fatty acids andThey participate in the metabolism of fatty acids and many other metabolites. Peroxisomes harbor enzymesmany other metabolites. Peroxisomes harbor enzymes that rid the cell of toxic peroxides.that rid the cell of toxic peroxides. Import proteins into the organelles and aid inImport proteins into the organelles and aid in proliferation. Peroxisomes can replicate by enlarging andproliferation. Peroxisomes can replicate by enlarging and then dividing.then dividing. Peroxisomes also play a role in the production of bilePeroxisomes also play a role in the production of bile acids and proteins.acids and proteins.
  • 4. Diseases/MalfunctionDiseases/Malfunction Adrenoleukodystrophy- AKA Addison-Schilder DiseaseAdrenoleukodystrophy- AKA Addison-Schilder Disease or Siemerling-Creutzfeldt Diseaseor Siemerling-Creutzfeldt Disease Zellweger SyndromeZellweger Syndrome (Nothing to do with Renee Zellweger)(Nothing to do with Renee Zellweger)