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2d histogram medical image segmentation 2d histogram matching brain tissue segmentation mr brain images 2d histogram classification data bias algorithmic bias algorithm interpretability transductive learning mri data histogram matching mr image artefacts literary review mr brain image sequence mr image segmentation using back-projection methodology segmentation using 2d histogram back-projection back-projection mr image sequence image segmentation image processing reproducibility engineering natural science open science plovdiv techsys '16 conference technical university of sofia eastern europe reproducible research computer vision medical imaging science speed up analysis of segmentation results data science machine learning gdpr ml algorithms bias reduction machine learning technologies machine learning algorithms ethical issues solving ethical problems bias in image recognition systems gender-bias in nlp ethical issues in chatbots ethical issues in credit score computation ethical issues in user profiling bulgaria transductive learning methods 2d histogram computation medical segmentation mr images jsc dsc evaluation metrics and algorithms parameters public datasets of mr images i ibsr18 ibsr20 brainweb execution time complexity ethical issues in ml algorithm personalization