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rheumatology masterinternalmedicine postgraduate malaysia crbsi disequilibrium syndrome intradialytic hypotension dss complications dialysis haemodialysis dmards non biologic upadacitinib janus kinase inhibitor psoriasis psoriatic athritis management diagnosis guillan barre syndrome chronicgout acuteflaregout mmed acr eular cpg chronicdisease gout adults most common acute premyelotic leukaemia acute myeloid leukaemia apl apml aml leukaemia medical medicine haematology gbs