This document summarizes the design process for the Third Set of Locks project in Panama. It describes the engineering teams involved in the design from 2008-2012. Key aspects of the design included numerical and physical models to simulate the lock chambers, modeling different components in software like Abaqus, and developing seismic criteria for lock structures. The design optimized the concrete and rebar quantities compared to the initial tender. Over 300 engineers from multiple firms worked on the design which included over 9,500 drawings and review of tens of thousands of shop drawings. The effort represented a major international engineering accomplishment.