Imidazole Derivatives Biological Activity And Synthetic ApproachesBalmukund Thakkar
油
This document summarizes biological activity and synthetic approaches for imidazole derivatives. It discusses the biological importance of natural imidazoles and synthetic imidazoles used as drugs, including antifungals, antithyroid drugs, and drugs affecting the sympathetic nervous system. It also reviews conventional imidazole synthesis methods and their limitations, and modern catalytic and non-catalytic methods that offer better yields, selectivity, and green chemistry profiles.
Imidazole Derivatives Biological Activity And Synthetic ApproachesBalmukund Thakkar
油
This document summarizes biological activity and synthetic approaches for imidazole derivatives. It discusses the biological importance of natural imidazoles and synthetic imidazoles used as drugs, including antifungals, antithyroid drugs, and drugs affecting the sympathetic nervous system. It also reviews conventional imidazole synthesis methods and their limitations, and modern catalytic and non-catalytic methods that offer better yields, selectivity, and green chemistry profiles.
Alkenes are unsaturated hydrocarbons containing one or more carbon-carbon double bonds. They are named using the IUPAC system which indicates the number of carbons in the longest chain, the location of the double bond, and any substituents. Alkenes can exist as geometric isomers (cis or trans) depending on the orientation of groups around the double bond. They are less volatile than similar alkanes due to stronger intermolecular forces between molecules.
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22. 3. Ph畉n 畛ng oxi h坦a
CnH2n
0
t
錚эрO2+ CO2 + H2O
3n
2
n n
*Nh畉n x辿t: Khi 畛t ch叩y 1hirocacbon m t畉o ra
nCO2 = nH2O th狸 hirocacbon 坦 l Anken ho畉c l
Xicloankan.
a. Ph畉n 畛ng oxi h坦a hon ton
0
t
錚эрO2+ CO2 + H2O2 2C2H4 3
V鱈 d畛:
T畛ng qu叩t:
![C担ng th畛c c畉u t畉o C担ng
th畛c
ph但n t畛
T棚n thay th畉 tnc, 0
C ts, 0
C Kh畛i l動畛ng
ri棚ng (g/cm3
)
CH2=CH2 C2H4 Eten -169 -104 0.57 (-1100
C)
CH2=CH-CH3 C3H6 Propen -186 -47 0.61 (-500
C)
CH2=CH-CH2-CH3 C4H8 But-1-en -185 -6 0.63 (-60
C)
CH2=C(CH3)2 C4H8 Metylpropen -141 -7 0.63 (-70
C)
CH2=CH-[CH2]2-CH3 C5H10 Pent-1-en -165 30 0.64 (200
C)
CH2=CH-[CH2]3-CH3 C6H12 Hex-1-en -140 64 0.68 (200
C)
CH2=CH-[CH2]4-CH3 C7H14 Hept-1-en -119 93 0.70 (200
C)
CH2=CH-[CH2]5-CH3 C8H16 Oct-1-en -102 122 0.72 (200
C)
II. TNH CH畉T V畉T L](https://image.slidesharecdn.com/anken-150526140907-lva1-app6891/85/Anken-11-320.jpg)
