Mark Lombard Sao Paulo Brazil EniFarMed Aug 2013
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The document discusses North Carolina's large and successful life sciences cluster. It describes the state's strengths as a place for biotechnology, including its major research universities and supportive ecosystem. It outlines the programs of the North Carolina Biotechnology Center, which has supported the cluster for 30 years through research funding, company creation initiatives, economic development efforts, and workforce development. As a result of these long-term efforts, North Carolina now has over 560 biotech companies, 60,000 employees in the industry, and the biotech sector generates $41 billion annually for the state economy.
Mark Lombard Sao Paulo Brazil EniFarMed Aug 2013
- 1. North Carolinas Life Sciences Cluster Impact of the North Carolina Biotechnology Center 21 August 2013 Mark Lombard, MBA Program Director, Bioscience Industrial Development North Carolina Biotechnology Center
- 2. North Carolina, USA NORTH CAROLINA BIOTECHNOLOGY CENTER
- 3. Life Sciences in North Carolina Place 3 major research universities in a 30 mile radius Ecosystem of supportive organizations, risk capital, entrepreneurial culture People Collaboration among visionary business, academia, govt leaders Attract and retain scientific and business talent Programs Company creation, attraction, retention, expansion programs Innovative workforce development programs Patience North Carolina Biotechnology Center: 30 years Research Triangle Park: 50+ years NORTH CAROLINA BIOTECHNOLOGY CENTER
- 4. Brazil and North Carolina NORTH CAROLINA BIOTECHNOLOGY CENTER
- 5. NORTH CAROLINA BIOTECHNOLOGY CENTER
- 6. Brazil and North Carolina NORTH CAROLINA BIOTECHNOLOGY CENTER
- 7. Sao Paulo and North Carolina Sao Paulo (2012) North Carolina (2012) Population: 41,901,219 Density: 170/km2 GDP (2010) Population: 9,752,073 Density: 83/km2 GDP (2010) US$615M US$15,322 per capita Machinery, auto and aviation, services, finance, textiles, oranges, sugar cane, coffee, life sciences $407M $42,884 per capita Cotton, tobacco, hogs, chickens, textiles, furniture Finance, advanced mfg, IT, life sciences NORTH CAROLINA BIOTECHNOLOGY CENTER
- 8. BIOTECHNOLOGY IN NORTH CAROLINA NORTH CAROLINA BIOTECHNOLOGY CENTER
- 9. Biotechnology: Heal, Fuel, Feed the World Global Challenges Human/Animal health Food availability & security Energy Environmental sustainability NORTH CAROLINA BIOTECHNOLOGY CENTER
- 10. Biotech in NC Large and Diverse 3rd Largest Life Science Cluster in the US Medical Devices & Diagnostics Contract Research & Manufacturing Biopharma Agricultural Biotech 560+ Companies 60,000+ Employees 21% 21% 58% R&D CRO/Testing Mfg/Prod
- 11. Specialization Biotech in NC Fastest Growing Growth Rate NORTH CAROLINA BIOTECHNOLOGY CENTER
- 12. Biotech in NC High Impact Jobs Average salary - $78,348 Nearly double the states private sector average 3.6 additional jobs for each biotech job 226,000 total jobs NORTH CAROLINA BIOTECHNOLOGY CENTER
- 13. Biotech in NC Annual Economic Impact Direct biotechnology sector revenues $41.2 billion Employee compensation $12.7 billion State and local revenues $1.92 billion NORTH CAROLINA BIOTECHNOLOGY CENTER
- 14. THE NORTH CAROLINA BIOTECHNOLOGY CENTER NORTH CAROLINA BIOTECHNOLOGY CENTER
- 15. NCBiotech Mission To provide long-term economic and societal benefits to North Carolina through support of biotech research, business, education and strategic policy statewide. NORTH CAROLINA BIOTECHNOLOGY CENTER
- 16. NCBiotech What We Do State-funded, private, non-profit corporation Portfolio of programs Research Business Education Economic Development NORTH CAROLINA BIOTECHNOLOGY CENTER
- 17. NCBiotech Programs Research Support Ideas Company Creation and Growth Statewide Econ Devel Products, Companies and Jobs Education, Networking and Other Programs NORTH CAROLINA BIOTECHNOLOGY CENTER
- 18. NCBiotech Programs Research Support Ideas Company Creation and Growth Statewide Econ Devel Products, Companies and Jobs Education, Networking and Other Programs NORTH CAROLINA BIOTECHNOLOGY CENTER
- 19. Research Support Grant funding for: New research ideas Build capacity equipment/faculty University/Company research projects $98 million granted $4 to $70 leveraged NORTH CAROLINA BIOTECHNOLOGY CENTER
- 20. NCBiotech Programs Research Support Ideas Company Creation and Growth Statewide Econ Devel Products, Companies and Jobs Education, Networking and Other Programs NORTH CAROLINA BIOTECHNOLOGY CENTER
- 21. Company Creation and Growth: NCBiotech Loan Program $50K - $250K low interest loans ROI = $117 per $1 loaned
- 22. Notable Recent Successes $96 million acquisition $25 million IPO BioKier $1.7 million seed financing Up to $1.6 million grant NORTH CAROLINA BIOTECHNOLOGY CENTER
- 23. Advanced Liquid Logic Microfluidics Lab Instruments 2003: $50,000 CFG Aug-2004: Company founded May-2005: $15,000 BDL 1 employee Sep-2005: $72,600 SBR 3 employees Sep-2006: $160,000 SGL 6 employees Jun-2009: $220,500 SGL 24 employees 2011: Launched products for newborn screening, genomic sample prep 2011-2013: NCBiotech VC events in Palo Alto, Boston, NYC Aug-2012 : $100,000 IFP Jul-2013 : $96M acquisition by Illumina 80 employees All loans repaid in full + interest and warrants >$50 million follow-on funding before acquisition Introductions to bankers and investors, NCBIP, Library, Jobs Board, NCBiotech Partnering 2011-2013, Corporate Communications
- 24. Heat Biologics Cell-based Cancer Immunotherapy 2008: Company founded in FL Aug-2011: Recruited to NC 2011-2012: Assistance with investor pitch 2011-2012: NCBiotech VC events in Palo Alto, Boston Nov-2011: $225,000 SGL - 2 NC employees Repaid in full with interest + warrants Apr-2012: Industrial Internship Program Apr-2013: $5 million VC round Jul-2013: $25 million IPO NASDAQ:HTBX 5 NC employees Investor introductions, partner introductions, foundation introductions, BATON, Library, Corporate Communications, NCBiotech Partnering 2012, BIO Pavilion
- 25. BioKier Medicinalize Gastric Bypass for Diabetes Nov-2008: Company founded Oct-2010: Emerging Company Preview Oct-2010: $250,000 SRL 2 employees Oct-2012: Pitch Scrub Nov-2012: SEBIO Presentation Apr-2013: Southeast Venture Philanthropy Summit May-2013: $250,000 SGL 3.5 employees Jul-2013: $1.7 million Broadview Ventures, AHA Investor introductions, NCBIP, Corporate Communications, Library, NCBiotech Partnering 2011-2013, LSBDP, Biotech Forums
- 26. Eboo Pharmaceuticals Opioid Modulators for CNS Diseases Feb-2012: Company founded May-2012: $30,000 CIL 2 NC employees Jun-2012: Introduction to Biogen IDEC Jul-2012: SBIR letter of support, recommended MJFF Oct-2012: Introductions to CEO candidates Nov-2012: Advice on business plan, investor pitch Dec-2012: Emerging Company Preview Feb-2013: Facilitated meeting with Eli Lilly Apr-2013: Southeast Venture Philanthropy Summit Jun-2013: Up to $1.6M grant Michael J. Fox Foundation BATON, Corporate Communications, Library
- 27. NCBiotech Programs Research Support Ideas Company Creation and Growth Statewide Econ Devel Products, Companies and Jobs Education, Networking and Other Programs NORTH CAROLINA BIOTECHNOLOGY CENTER
- 28. Statewide Offices Western (Asheville) Greater Charlotte Piedmont Triad (Winston-Salem) Research Triangle Park Eastern (Greenville) Southeastern (Wilmington) NORTH CAROLINA BIOTECHNOLOGY CENTER
- 29. Economic Development Since July 2010 21 projects 1,754 employees Ripple effects: 7,803 total jobs $490 million in payroll $59 million in state and local revenues $2.0B in economic activity NORTH CAROLINA BIOTECHNOLOGY CENTER
- 30. Economic Development Novartis Vaccines BIO 2004 in San Francisco Chiron 2006: project announced 2009: plant opens 2012: production begins 2012: $36M expansion 2013: $60M expansion Today: >$1B invested, 700 employees, will grow to 1000 NORTH CAROLINA BIOTECHNOLOGY CENTER
- 31. Economic Development Medicago Early 2010: introduced by Canadian Consulate Mid 2010: DARPA, ARE Late 2010: construction begins Mid 2012: 10M flu doses in one month 2013: Acquired by Mitsubsihi in a $357M deal NORTH CAROLINA BIOTECHNOLOGY CENTER
- 32. Economic Development Recent Announcements 2011: Sequenom (molecular diagnostics) 242 jobs, $19M investment 2012: Aerocrine (asthma diagnostics) 45 jobs 2013: bioMerieux: (in vitro diagnostics) 44 jobs, $44M investment 2013: Syngenta (agricultural biotech) 150 jobs, $94M investment NORTH CAROLINA BIOTECHNOLOGY CENTER
- 33. NCBiotech Programs Research Support Ideas Company Creation and Growth Statewide Econ Devel Products, Companies and Jobs Education, Networking and Other Programs NORTH CAROLINA BIOTECHNOLOGY CENTER
- 34. Workforce and Education 1900+ teachers trained 50,000 students reached each year $7M in grants for lab equipment & new courses 8,000+ BioWork manuals distributed to colleges NORTH CAROLINA BIOTECHNOLOGY CENTER
- 35. Biomanufacturing Workforce NCBIOIMPACT Industry-driven biopharma manufacturing training and education Emerging and existing labor BTEC 82,500 SF; $60M $12.5M equipment cGMP pilot plant NORTH CAROLINA BIOTECHNOLOGY CENTER
- 36. Networking and Community High-profile conferences Hamner Conference Center 30,000 guests annually Networking groups More than 3,000 attendees Biotech Library NCBiotech Job Network And much more NORTH CAROLINA BIOTECHNOLOGY CENTER
- 37. Looking Ahead NORTH CAROLINA BIOTECHNOLOGY CENTER
- 39. Life Sciences in North Carolina Place 3 major research universities in a 30 mile radius Ecosystem of supportive organizations, risk capital, entrepreneurial culture People Collaboration among visionary business, academia, govt leaders Attract and retain scientific and business talent Programs Company creation, attraction, retention, expansion Innovative workforce development programs Patience North Carolina Biotechnology Center: 30 years Research Triangle Park: 50+ years NORTH CAROLINA BIOTECHNOLOGY CENTER
- 40. Thank You Mark Lombard Program Director, Bioscience Industrial Development North Carolina Biotechnology Center