BREAST CANCER STAGING.ppt
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This document outlines the staging system for breast cancer. Stage 0 is carcinoma in situ with no lymph node or distant metastasis. Stages 1-3 classify tumors based on size and extent of local and regional lymph node involvement. Stage 4 is any tumor with distant metastasis. Common chemotherapy regimens for breast cancer are listed, including CMF, FAC, and AC. Trastuzumab and Laptinib are targeted therapies for HER2 positive breast cancer.
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Solubilization in Pharmaceutical Sciences: Concepts, Mechanisms & Enhancement...KHUSHAL CHAVAN
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This presentation provides an in-depth understanding of solubilization and its critical role in pharmaceutical formulations. It covers:
Definition & Mechanisms of Solubilization
Role of surfactants, micelles, and bile salts in drug solubility
Factors affecting solubilization (pH, polarity, particle size, temperature, etc.)
Methods to enhance drug solubility (Buffers, Co-solvents, Surfactants, Complexation, Solid Dispersions)
Advanced approaches (Polymorphism, Salt Formation, Co-crystallization, Prodrugs)
This resource is valuable for pharmaceutical scientists, formulation experts, regulatory professionals, and students interested in improving drug solubility and bioavailability.Multimodal Approaches to Clitoral Augmentation for FGM (PRP _ filler)"
Multimodal Approaches to Clitoral Augmentation for FGM (PRP _ filler)"Rehab Aboshama
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Multimodal Approaches to Clitoral Augmentation for FGM (PRP _ filler)"
Correlation of vitamin D level with prediabetes status_Dr Ahmed Al Montasir_f...
Correlation of vitamin D level with prediabetes status_Dr Ahmed Al Montasir_f...zilkerapurbo
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Correlation of vitamin D level with prediabetes statusBest Sampling Practices Webinar USP <797> Compliance & Environmental Monito...
Best Sampling Practices Webinar USP <797> Compliance & Environmental Monito...NuAire
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Best Sampling Practices Webinar USP <797> Compliance & Environmental Monitoring
Are your cleanroom sampling practices USP <797> compliant? This webinar, hosted by Pharmacy Purchasing & Products (PP&P Magazine) and sponsored by NuAire, features microbiology expert Abby Roth discussing best practices for surface & air sampling, data analysis, and compliance.
Key Topics Covered:
鏝 Viable air & surface sampling best practices
鏝 USP <797> requirements & compliance strategies
鏝 How to analyze & trend viable sample data
鏝 Improving environmental monitoring in cleanrooms
･ Watch Now: https://www.nuaire.com/resources/best-sampling-practices-cleanroom-usp-797
Stay informedfollow Abby Roth on LinkedIn for more cleanroom insights!Diabetic Ketoacidosis (DKA) & Its Management Protocol
Diabetic Ketoacidosis (DKA) & Its Management ProtocolDr Anik Roy Chowdhury
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Dr. Anik Roy Chowdhury
MBBS, BCS(Health), DA, MD (Resident)
Department of Anesthesiology, ICU & Pain Medicine
Shaheed Suhrawardy Medical College Hospital (ShSMCH)
One Health Rabies Control in Indonesia_APCAT meeting May 2022.pptx
One Health Rabies Control in Indonesia_APCAT meeting May 2022.pptxWahid Husein
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What is FAO doing to support rabies control programmes in Indonesia using One Health approach
Local Anesthetic Use in the Vulnerable Patients
Local Anesthetic Use in the Vulnerable PatientsReza Aminnejad
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Local anesthetics are a cornerstone of pain management, but their use requires special consideration in vulnerable groups such as pediatric, elderly, diabetic, or obese patients. In this presentation, well explore how factors like age and physiology influence local anesthetics' selection, dosing, and safety. By understanding these differences, we can optimize patient care and minimize risks.
Acute & Chronic Inflammation, Chemical mediators in Inflammation and Wound he...
Acute & Chronic Inflammation, Chemical mediators in Inflammation and Wound he...Ganapathi Vankudoth
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BREAST CANCER STAGING.ppt
- 1. Stage 0: Tis N o M o Tis = carcinoma in situ N o= no reginal lymph node metastasis M o= no distant metastasis
- 2. Stage 1: T1 N o M o T 1 = tumor 2cm or less in greatest dimension
- 3. Stage 2a: To N1 Mo N1= metastasis to ipsilateral ax. Nodes T1 N1 Mo mobile T2 N o Mo T2= tumor>2cm but <5cm in greatest dimention
- 4. Stage 2b: T2 N1 Mo T3 N o Mo T3= tumor size > 5cm in greatest dimention
- 5. Stage 3a N2a =met to ipsilat axillary node , fixed or matted N2b= met to ipsilat int mammary node in absence of ax. node T o N2 M o T1 N2 Mo T2 N2 Mo T3 N1 Mo T3 N2 Mo
- 6. Stage 3b T4a= extension to chest wall T4b= edema(Peaud Orange), T4c= both T4a & T4b T4d= inflammatory carcinoma T4 No Mo T4 N1 Mo T4 N2 Mo T4 N2 Mo
- 7. Stage 3 c N3a= met to ipsilat infraclavicular LN N3b= ipsilat Internal mammary & axillary LN N3c= ipsilat supraclavicular LN Any T N3 Mo
- 8. Stage 4 : Any T any N + M1 M1= distant metastasis
- 9. C M F regimen C cyclophosphamide M methotrexate F 5 flurouracil FAC regimen F 5 flurouracil A adriamycin(doxorubicin) C cyclophosphamide AC regimen A adriamycin C - cyclophosphamide
- 10. Trastuzumab : is a humanized murine (Herceptin) monoclonal antibody raised against erb B2, HER 2 surface receptor Laptinib : a dual inhibitor of both - EGFR - HER 2