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痢里 裡
里立 裡離裡立
慮留僚留溜留 竜僚劉虜凌
MedicalWriter
abenekou.net
medical.papers@abenekou.net
 The purists would say that up to 99% of published articles
belong in the bin and should certainly not be used to inform
practice
凌旅侶留 隆侶亮凌旅竜竜僚
侶粒流: Trisha Greenhalgh. How to read a paper. The
basics of evidence based medicine. BMJ Books 2001
凌旅侶留 里 竜 竜旅凌隆旅虜略 亮竜 侶了 IF
 BMJ IF 17,2
 CMAJ IF 6,5
 JAMA IF 30
 Lancet IF 39,2
 NEJM IF 54,2
 Am J Respiratory & Critical Care Med IF 11,0
 Arch General Psychiatry IF 13,8
 Circulation IF 15,2
 Diabetes IF 8,3
 J Clin Oncology IF 17,9
Figure 2. Quality scores, reporting of allocation concealment, and inclusion of trial flow diagram significantly
improved over time.
To MJ, Jones J, Emara M, Jadad AR (2013) Are Reports of Randomized Controlled Trials Improving over Time? A Systematic
Review of 284 Articles Published in High-Impact General and Specialized Medical Journals. PLoS ONE 8(12): e84779.
doi:10.1371/journal.pone.0084779
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0084779
51,9%
58,4%
84,4%
 Annals of Oncology IF 6,6
 British J Cancer IF 4,8
 Breast Cancer Research & Treatment IF 4,2
 Cancer IF 4,9
 European J Cancer IF 4,8
 JCO IF 17,9
 J Nat Cancer Inst IF 15,1
 Lancet IF 39,2
 Lancet Oncology IF 24,7
 NEJM IF 54,42
凌旅侶留 隆侶亮凌旅竜竜僚 亮竜了竜ホ 略侶  侶僚
凌粒虜凌了凌粒溜留 2005-2009 竜 10 凌粒虜凌了凌粒旅虜略 竜旅凌隆旅虜略
% 里 亮竜 竜留虜流 竜旅粒留流 凌旅竜溜僚
% 里 亮竜 竜留虜流 竜旅粒留流 凌旅竜溜僚
% 里 亮竜 竜留虜流 竜旅粒留流 凌旅竜溜僚 侶 亮竜了劉侶 凌
虜留慮凌溜龍凌僚 侶僚 凌旅侶略 侶
侶粒劉:
1. Methodological reporting of randomized controlled trials in major hepato-gastroenterology journals in 2008 and 1998: a comparative
study. Wang Ji-Lin et al. BMC Medical Research Methodology 2011,11:110
2. Quality of reporting of modern RCTs in medical oncology: a systematic review. Peron J.ate al. J Natl Cancer Inst 2012;104:982989
 旅留溜 虜留虜劉 隆侶亮凌旅竜竜旅 略凌僚 竜 了留 留
竜旅侶亮凌僚旅虜略 竜旅凌隆旅虜略
 里凌 侶了 impact factor 凌 竜旅凌隆旅虜凌 虜留旅 凌
peer review process 隆竜僚 竜溜僚留旅 竜粒粒侶劉 凌旅侶留
 旅留溜 竜亮竜溜 留凌留溜龍凌亮竜 留僚 亮留 竜溜僚留旅 流旅亮侶
亮旅留 隆侶亮凌溜竜侶
凌 凌旅 隆侶亮凌旅竜竜旅 劉凌僚 凌竜溜 Peer
review 粒旅留溜 竜亮竜溜 僚留 旅 留両旅凌了凌粒凌亮竜;
凌侶慮流亮留留
  Uniform Requirements for Submission to
Biomedical Journals International
Committee of Medical Journal Editors www.icmje.org
 CONSORT, Consolidated Standards of Reporting
Trials,
www.consort-statement.org
Critical appraisal
Critical appraisal
Introduction
INTRODUCTION
里凌 introduction 劉竜旅 僚留 竜溜僚留旅
 旅虜
 裡僚竜虜旅虜
 留 凌凌慮竜竜溜 留亮劉 凌僚 留僚留粒僚マ侶 凌 凌 劉竜僚留 龍流侶亮留
 留 亮侶僚 了留竜旅略龍竜旅
 留 亮侶僚 虜凌略龍竜旅 凌僚 留僚留粒僚マ侶
 留 虜留略 凌 竜僚隆旅留劉凌僚 凌 凌 虜竜溜亮竜僚凌
 里溜了凌
 旅留粒粒流
 竜慮凌隆凌了凌粒溜留
 凌竜溜 凌 竜隆旅留亮 僚留
留留僚流竜旅 凌 竜マ侶亮留;
 竜 竜僚隆旅留劉竜旅 僚留 隆 留
留凌竜了劉亮留留;
 凌竜了劉亮留留
 里旅 劉硫粒留了竜 侶 亮竜了劉侶;
 裡龍流侶侶
 里旅 侶亮留溜僚竜旅 凌 留凌劉了竜亮留;
束if you are going to trash a paper, you
should do so before you even look at the
results
Trisha Greenhalgh How to read a paper
BMJ Books, 2nd ed. 2001
マ 僚留 隆旅留硫略龍凌亮竜;
 留溜隆留 凌留溜留
留 亮侶 留両旅了凌粒竜
竜粒留溜竜 (旅 凌 impact
factor)
METHODS
Trisha Greenhalgh: 束 旅 2 マ竜
略竜旅 凌 methods 亮凌 僚留
留凌留溜 留僚 慮留 流 侶
隆侶亮凌溜竜侶 流 旅 凌 manuscript損
Methods
HOW TO READ A PAPER The basics of evidence
based medicine. BMJ Books 2nd edition.
Critical appraisal
Critical appraisal
旅 凌亮略隆竜 竜溜僚留旅 亮凌旅竜;
 了劉粒凌亮竜 凌僚 溜僚留虜留 留旅虜ホ 留留虜侶旅旅虜ホ
 僚 隆竜僚 竜溜僚留旅, 劉竜旅 僚留 劉竜旅 粒溜僚竜旅 虜留略了了侶了凌 adjustment
僚留劉凌僚留旅 留 留凌竜了劉亮留留 留 了留 留
竜 凌 束凌劉慮侶虜留僚損 凌 methods;
 流 略竜旅 selective reporting?
RESULTS
DayDay
凌凌流 留 粒留流亮留留
竜旅竜虜旅虜略 粒留流亮留留 (Papp et al)
DISCUSSION
 両流粒侶侶 僚 亮竜留亮略僚
 留 留留僚侶慮凌僚 了留 留 竜流亮留留 凌
粒竜僚僚流慮侶虜留僚 竜 methods & results
 了留 留 侶亮留旅虜略了略慮侶
 僚竜留虜劉亮劉粒竜慮凌 隆竜溜粒亮留凌(underpowered study)
 裡粒旅虜凌溜留略粒凌僚竜 (confounders)
了了留 侶亮竜溜留 凌凌流
 了竜粒凌 硫旅硫了旅凌粒留溜留
 Authors affiliations
 Acknowledgments
 Disclosure of Potential
Conflicts of Interest
 律凌侶粒 虜留旅 亮亮竜凌流
凌
裡僚略 虜留旅 凌硫留略 了略慮侶
 僚溜了侶侶 侶 留旅旅虜流 侶亮留溜留  虜了旅僚旅虜流
侶亮留溜留
 裡亮竜留亮留凌了凌粒溜留
 竜旅硫竜硫留溜侶 凌虜留留了流竜僚 竜溜 留僚留虜僚
凌旅竜溜僚
 凌 留粒僚凌竜溜 confounders & study limitations
裡略了亮留留 凌  / IV
里竜了旅虜劉 竜流竜旅 粒旅留 侶僚 隆侶亮凌溜竜侶
 里侶僚 虜留留了留硫留溜僚;
 里侶僚 旅竜;
 竜 竜僚隆旅留劉竜旅;
Elizabeth Wager, Fiona Godlee, Tom Jefferson,
How to survive peer review, BMJ Books 2002
裡裡 離律痢裡里立
慮留僚留溜留 竜僚劉虜凌
MedicalWriter
abenekou.net
medical.papers@abenekou.net
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Critical appraisal

  • 1. 痢里 裡 里立 裡離裡立 慮留僚留溜留 竜僚劉虜凌 MedicalWriter abenekou.net medical.papers@abenekou.net
  • 2. The purists would say that up to 99% of published articles belong in the bin and should certainly not be used to inform practice 凌旅侶留 隆侶亮凌旅竜竜僚 侶粒流: Trisha Greenhalgh. How to read a paper. The basics of evidence based medicine. BMJ Books 2001
  • 3. 凌旅侶留 里 竜 竜旅凌隆旅虜略 亮竜 侶了 IF BMJ IF 17,2 CMAJ IF 6,5 JAMA IF 30 Lancet IF 39,2 NEJM IF 54,2 Am J Respiratory & Critical Care Med IF 11,0 Arch General Psychiatry IF 13,8 Circulation IF 15,2 Diabetes IF 8,3 J Clin Oncology IF 17,9
  • 4. Figure 2. Quality scores, reporting of allocation concealment, and inclusion of trial flow diagram significantly improved over time. To MJ, Jones J, Emara M, Jadad AR (2013) Are Reports of Randomized Controlled Trials Improving over Time? A Systematic Review of 284 Articles Published in High-Impact General and Specialized Medical Journals. PLoS ONE 8(12): e84779. doi:10.1371/journal.pone.0084779 http://www.plosone.org/article/info:doi/10.1371/journal.pone.0084779 51,9% 58,4% 84,4%
  • 5. Annals of Oncology IF 6,6 British J Cancer IF 4,8 Breast Cancer Research & Treatment IF 4,2 Cancer IF 4,9 European J Cancer IF 4,8 JCO IF 17,9 J Nat Cancer Inst IF 15,1 Lancet IF 39,2 Lancet Oncology IF 24,7 NEJM IF 54,42 凌旅侶留 隆侶亮凌旅竜竜僚 亮竜了竜ホ 略侶 侶僚 凌粒虜凌了凌粒溜留 2005-2009 竜 10 凌粒虜凌了凌粒旅虜略 竜旅凌隆旅虜略
  • 6. % 里 亮竜 竜留虜流 竜旅粒留流 凌旅竜溜僚
  • 7. % 里 亮竜 竜留虜流 竜旅粒留流 凌旅竜溜僚
  • 8. % 里 亮竜 竜留虜流 竜旅粒留流 凌旅竜溜僚 侶 亮竜了劉侶 凌 虜留慮凌溜龍凌僚 侶僚 凌旅侶略 侶 侶粒劉: 1. Methodological reporting of randomized controlled trials in major hepato-gastroenterology journals in 2008 and 1998: a comparative study. Wang Ji-Lin et al. BMC Medical Research Methodology 2011,11:110 2. Quality of reporting of modern RCTs in medical oncology: a systematic review. Peron J.ate al. J Natl Cancer Inst 2012;104:982989
  • 9. 旅留溜 虜留虜劉 隆侶亮凌旅竜竜旅 略凌僚 竜 了留 留 竜旅侶亮凌僚旅虜略 竜旅凌隆旅虜略 里凌 侶了 impact factor 凌 竜旅凌隆旅虜凌 虜留旅 凌 peer review process 隆竜僚 竜溜僚留旅 竜粒粒侶劉 凌旅侶留 旅留溜 竜亮竜溜 留凌留溜龍凌亮竜 留僚 亮留 竜溜僚留旅 流旅亮侶 亮旅留 隆侶亮凌溜竜侶 凌 凌旅 隆侶亮凌旅竜竜旅 劉凌僚 凌竜溜 Peer review 粒旅留溜 竜亮竜溜 僚留 旅 留両旅凌了凌粒凌亮竜;
  • 10. 凌侶慮流亮留留 Uniform Requirements for Submission to Biomedical Journals International Committee of Medical Journal Editors www.icmje.org CONSORT, Consolidated Standards of Reporting Trials, www.consort-statement.org
  • 14. INTRODUCTION 里凌 introduction 劉竜旅 僚留 竜溜僚留旅 旅虜 裡僚竜虜旅虜 留 凌凌慮竜竜溜 留亮劉 凌僚 留僚留粒僚マ侶 凌 凌 劉竜僚留 龍流侶亮留 留 亮侶僚 了留竜旅略龍竜旅 留 亮侶僚 虜凌略龍竜旅 凌僚 留僚留粒僚マ侶 留 虜留略 凌 竜僚隆旅留劉凌僚 凌 凌 虜竜溜亮竜僚凌
  • 15. 里溜了凌 旅留粒粒流 竜慮凌隆凌了凌粒溜留 凌竜溜 凌 竜隆旅留亮 僚留 留留僚流竜旅 凌 竜マ侶亮留; 竜 竜僚隆旅留劉竜旅 僚留 隆 留 留凌竜了劉亮留留; 凌竜了劉亮留留 里旅 劉硫粒留了竜 侶 亮竜了劉侶; 裡龍流侶侶 里旅 侶亮留溜僚竜旅 凌 留凌劉了竜亮留; 束if you are going to trash a paper, you should do so before you even look at the results Trisha Greenhalgh How to read a paper BMJ Books, 2nd ed. 2001 マ 僚留 隆旅留硫略龍凌亮竜;
  • 16. 留溜隆留 凌留溜留 留 亮侶 留両旅了凌粒竜 竜粒留溜竜 (旅 凌 impact factor) METHODS
  • 17. Trisha Greenhalgh: 束 旅 2 マ竜 略竜旅 凌 methods 亮凌 僚留 留凌留溜 留僚 慮留 流 侶 隆侶亮凌溜竜侶 流 旅 凌 manuscript損 Methods HOW TO READ A PAPER The basics of evidence based medicine. BMJ Books 2nd edition.
  • 20. 旅 凌亮略隆竜 竜溜僚留旅 亮凌旅竜; 了劉粒凌亮竜 凌僚 溜僚留虜留 留旅虜ホ 留留虜侶旅旅虜ホ 僚 隆竜僚 竜溜僚留旅, 劉竜旅 僚留 劉竜旅 粒溜僚竜旅 虜留略了了侶了凌 adjustment 僚留劉凌僚留旅 留 留凌竜了劉亮留留 留 了留 留 竜 凌 束凌劉慮侶虜留僚損 凌 methods; 流 略竜旅 selective reporting? RESULTS
  • 23. DISCUSSION 両流粒侶侶 僚 亮竜留亮略僚 留 留留僚侶慮凌僚 了留 留 竜流亮留留 凌 粒竜僚僚流慮侶虜留僚 竜 methods & results 了留 留 侶亮留旅虜略了略慮侶 僚竜留虜劉亮劉粒竜慮凌 隆竜溜粒亮留凌(underpowered study) 裡粒旅虜凌溜留略粒凌僚竜 (confounders)
  • 24. 了了留 侶亮竜溜留 凌凌流 了竜粒凌 硫旅硫了旅凌粒留溜留 Authors affiliations Acknowledgments Disclosure of Potential Conflicts of Interest 律凌侶粒 虜留旅 亮亮竜凌流 凌
  • 25. 裡僚略 虜留旅 凌硫留略 了略慮侶 僚溜了侶侶 侶 留旅旅虜流 侶亮留溜留 虜了旅僚旅虜流 侶亮留溜留 裡亮竜留亮留凌了凌粒溜留 竜旅硫竜硫留溜侶 凌虜留留了流竜僚 竜溜 留僚留虜僚 凌旅竜溜僚 凌 留粒僚凌竜溜 confounders & study limitations 裡略了亮留留 凌 / IV
  • 26. 里竜了旅虜劉 竜流竜旅 粒旅留 侶僚 隆侶亮凌溜竜侶 里侶僚 虜留留了留硫留溜僚; 里侶僚 旅竜; 竜 竜僚隆旅留劉竜旅; Elizabeth Wager, Fiona Godlee, Tom Jefferson, How to survive peer review, BMJ Books 2002