際際滷

際際滷Share a Scribd company logo
Base油Camp油Presentation
How油to油talk油about油Redox油Signaling
        Gary油Samuelson,油Ph.D.
Redox油Signaling油is油an油Exploding油
           Field油of油Science




Books
Redox油Biochem
       Ruma油Banerjee              Journals                      Conferences
Antioxidant油and油Redox油                                          The油Gordon油Research油
Regulation油of油Genes
                                   Antiox油&油Redox油Signaling
                                                                 Conference on油Thiolbased油
       Chandan油K油Sen              Physiol油Genomics             Redox Regulation油and油Signaling
Redox油Signaling油in油Biology油and油   Am.油J.油of油Physiology         4th油International油Conference油
Medicine                                                         on油Oxidative/Nitrosative油Stress油
       Claus油Jacob
                                   The油J.油of油Immunology
                                                                 and油Disease油
RedoxMediated油Signal油            PNAS                         International油Symposium油on油
Transduction:油Methods油and油         Arteriosclerosis,油Thromb.油   the油Pathophysiology油of油
Protocols                                                        Reactive油Oxygen油and油Nitrogen油
       John油T油Hancock
                                   Vasc.
                                                                 Species油
Redox油Protemics                   Hundreds油More                Many油more
       Nick油Lane
And油More
Signaling油Molecules油in油ASEA油Come油From油
             Salt油and油Water
                                           Salt
                                Na+                   Cl -                        Water
                H
                                                                     H

                        O
                                       N          N                          O

                H
                                      Nitrogen                       H
                            REDuction             OXidation

                                                                         H
                                 H
            H                                                                       Super油
Hydrogen油                                                                           Oxides
Peroxide                                               O         O
                    O       O
                                       More油                                 Cl


  Nitric油
                                      than油20                H
                                                                                     Hypo油
                    N       O
  Oxide                               Molecule                   O                  chlorites油
                                         s油
                                                                                     μ
Do油we油need油to油become油experts油in油
Redox油Biochemistry?油油Answer:油No




    Dr. Ruma Banerjee
What油are油Redox油Signaling油
              Molecules?
   They油are油produced油inside油our油cells
   They油help油cells油communicate油with油each油other
   They油help油tissues油heal油themselves
   The油redox油signaling油molecules油in油ASEA油are油
    actual油molecules油made油from油salt油and油water
How油Do油Redox油Signaling油Molecules油
            Work?
 They油help油cells油communicate油with油each油other
 They油increase油the油bars油on油our油cell油phones
 When油our油cells油have油a油problem,油they油need油to油
  talk油to油each油other
 If油they油cannot油talk油the油problems油become油worse
 If油they油can油talk,油the油problems油can油be油solved
Cells油Need油to油Communicate!!!
   Cell              Cell

             C                 C
             e                 e
             ll                ll



      Mail              Mail
      box               box
Cells油are油Like油Houses油that油Shelter油Life
           Sustaining油Activity




Fireplace,油Furnace,油Stove,油Heaters油油油>油油油油油油油Mitochondria
Mail油Slots油and油Sorting油油>油油油油油油油Receptors,油Vesicles,油Golgi
Appliances,油Tools,油etc.油油>油油油油油油油Micromachines
Walls,油Floors,油Plumbing,油Wires油>油油油油油油油Membranes,油tubules
We油can油think油of油Cells油as油
 Houses油Along油Streets
                                                                    C
                                    C                               e
                                    e                               l
                                    l                               l
                                    l
                                                           M
                                                           ai
                           M                                l
                           ai                              b
                            l                              o
                           b                               x
                           o
                           x




                                                                C
                                C                               e
                                e
                                l
                                        Blood油                  l
                                                                l
Street
                                l       Vessel
                                                      M
                                                      ai
                      M                                l
                      ai                              b
                       l                              o
                      b                               x
                      o
                      x




                                                                C
                                C                               e
                                e                               l
                                l                               l
                                l
                                                 M
                                                 ai
                 M                                l
                 ai                              b
                  l                              o
                 b                               x
                 o
                 x
Cells油live油in油Communities油Where油
They油Must油Communicate油to油Survive
When油Cells油Have油a油Problem
They油Need油Emergency油Response
                      C                        CC                      C                        C
                      e                        ee                      e                        e
                      l                        ll                      l                        l
                      l                        ll                      l                        l

             M                      M M                       M                       M
             ai                     aiai                      ai                      ai
              l                      ll                        l                       l
             b                      bb                        b                       b
             o                      oo                        o                       o
             x                      xx                        x                       x




                  C                        C                       C                        C
                  e                        e                       e                        e
                  l                        l                       l                        l
                  l                        l                       l                        l

        M                      M
                               M                         M
                                                         M                       M
        ai                     ai
                               ai                        ai
                                                         ai                      ai
         l                      l
                                l                         l
                                                          l                       l
        b                      b
                               b                         b
                                                         b                       b
        o                      o
                               o                         o
                                                         o                       o
        x                      x
                               x                         x
                                                         x                       x




                  C                        C                       C                       CC
                  e                        e                       e                       ee
                  l                        l                       l                       ll
                  l                        l                       l                       ll

   M                      M                         M                      MM
   ai                     ai                        ai                     ai
                                                                            ai
    l                      l                         l                      ll
   b                      b                         b                      b b
   o                      o                         o                      o o
   x                      x                         x                      xx
Redox Signaling油Helps油Cells油Detect油the油
         Extent油of油the油Damage
Normal油
Healthy油Cells油
Have油Fires油
and油Smoke油
(Controlled油
Oxidation油)

When油the油
Fire油and油
Smoke油Get油
out油of油
Controll,油
Cells油need油
Help
What油Happens油When油Cells油Need油
             Help?
 They油must油be油able油to油send油a油redox油signal
 Redox油Signaling油Molecules油carry油the油signals
 Fire油Marshalls油see油these油smoke油signals油and油
  call油in油the油fire油crew
 Fire油Crews油put油out油the油fires油(with油antioxidants)油
  and油help油repair油the油damage油or油destroy油and油
  rebuild油the油house
Why油Do油I油Need油Redox油Signaling油
            Molecules?
 Your油body油has油tens油of油billions油of油cells油that油
  need油repair油or油replacement油every油day,油even油
  more油if油you油are油sick油or油sore
 As油you油age油and油especially油if油you油are油sick油you油
  do油not油have油enough油redox油signaling油molecules油
  to油handle油the油demand
 If油your油cells油are油not油able油to油call油for油help,油they油
  will油continue油to油burn油(oxidize)油and油will油not油
  be油repaired油or油replaced油fast油enough
Does油Your油Brain油and油Nervous油System油
Need油to油Be油Protected油and油Repaired?
Does油Your油Heart油and油Veins油Need油to油be油
             Repaired?
Do油Your油Muscles油Need油to油Be油Repaired?
If油You油Answered油Yes油to油Any油of油
These,油You油Need油Redox油Signaling油
          Molecules!
Redox Imbalance油(Oxidative油Stress)油
Signals油ProtectRepairReplace油Response
Innovation:油Infuse油Balanced油Redox Signaling油
Molecules油(Lost油by油Aging油or油Stress)油back油into油Tissues
Redox油Signaling油Technology油is油Destined油
to油Fuel油the油Greatest油Advances油in油Medical油
          Science油This油Century
 Redox油Signaling油is油fundamental油to油all油
  biological油multicellular油processes
 It油is油nonspecific,油nontoxic油and油applicable油
  to油a油broad油range油of油processes油and油pathways
 It油is油at油the油very油core油of油mediating油and油
  regulating油the油mechanisms油that油restore油
  functionality油and油health
Increasing油Proper油Redox油Signaling油in油Your油
  Body油is油the油Single油Most油Important油Thing油
        You油Can油Do油For油Your油Health
 Redox油Signaling油is油absolutely油necessary油for油all油
  living油things油on油earth油with油more油than油one油cell
 Redox油Signaling油Molecules油in油proper油balance油
  cannot油hurt油you,油they油are油in油all油of油your油cells油
  already,油you油just油need油more油of油them油to油keep油
  the油cells油healthy
 You油need油Redox油Signaling油Molecules油so油that油
  your油body油can油restore油and油maintain油its油health
Stable油Balanced油Redox Signaling油
     Molecules油in油ASEA油Confirmed
 ASEA油contains油a油balance油of油ROS油and油RS油
 Fluorescent油Indicators油Detect油ROS油
  Components油in油ASEA
 ESR油and油EPR油methods油were油used油to油verify油
  existence油of油stable油ROS油components
 Low油Temperature油Mass油Spectroscopy油used油
  find油several油ionic油components油of油ASEA
ASEA油Generates油and油Enhances油
 Antioxidants油with油Zero油Toxic油Effects油
 ASEA油causes油no油signs油of油toxicity油on油human油
  cells,油even油on油a油genetic油level
 ASEA油causes油a油significant油increase油(500%)油in油
  the油effectiveness油of油Antioxidants
 ASEA油causes油enhanced油detection油of油damaged油
  cells
 ASEA油causes油increased油messenger油sensitivity
 ASEA油causes油old油(senescent)油cells油to油revive
Scientists油Have油Proven油that油There油Are油
 Redox油Signaling油Molecules油in油ASEA
 ASEA油contains油the油same油balance油of油Redox油
  Signaling油Molecules油that油already油exist油in油the油fluids油
  inside油your油body,油cells油and油tissues
 Complex油analysis油has油been油done油to油prove油that油
  ASEA油has油Redox油Signaling油Molecules油and油that油
  they油are油safe
 ASEA油helps油put油out油the油fires油in油your油body,油helps油
  the油body油restore油the油cells油proper油function油and油
  causes油damaged油cells油to油revitalize
Groundwork油Toward油Redox Signaling油
         Development
 Can油stable油complexes油of油Redox Signaling油
  Molecules油be油manufactured?油油YES.
 Can油the油bioactivity油of油such油be油
  characterized?油油YES.
 Can油such油complexes油be油nontoxic油and油
  readily油absorbed?油油YES.
 Can油such油a油technology油be油commercialized?油
  It油is油up油to油you!
The油Most油Effective油Way油to油Take油ASEA
 Pour油into油a油clean油glass油measuring油cup
 2油oz.油twice油a油day油 maintenance油dose
 4油oz.油twice油daily油 mild油challenges
 8油oz.油twice油daily油 severe油challenges
 遜油oz油twice油daily油or油spray油in油mouth油 reduce油
  detox油symptoms
 Do油not油eat油5油min.油before油or油after油taking油ASEA
Can油We油Tell油the油Story油of油the油
Science油of油ASEA油So油That油Everyone油
Can油Understand油It油and油Repeat油it?

 If油we油can油ASEA油will油make油it油into油
 more油of油the油hands油that油need油it

More Related Content

Similar to How To Talk About ASEA By Dr. Gary Samuelson, PhD (9)

Bioenergy X1an China B
Bioenergy X1an China BBioenergy X1an China B
Bioenergy X1an China B
eboroil
Gatot trimulyadi- Radiation Grafting
Gatot trimulyadi- Radiation GraftingGatot trimulyadi- Radiation Grafting
Gatot trimulyadi- Radiation Grafting
Dr.Ir. Gatot Trimulyadi Rekso, M.Si- Indonesia
Chapter 11 dna biology & technology
Chapter 11 dna biology & technologyChapter 11 dna biology & technology
Chapter 11 dna biology & technology
cetla1
Molbiol 2011-10-proteins
Molbiol 2011-10-proteinsMolbiol 2011-10-proteins
Molbiol 2011-10-proteins
Nikolay Vyahhi
Molbiol 2011-10-proteins
Molbiol 2011-10-proteinsMolbiol 2011-10-proteins
Molbiol 2011-10-proteins
Nikolay Vyahhi
123.202 Lecture 7 - alkenes
123.202 Lecture 7 - alkenes123.202 Lecture 7 - alkenes
123.202 Lecture 7 - alkenes
Gareth Rowlands
Chemistry 3
Chemistry 3Chemistry 3
Chemistry 3
Blaschke's Class
Snns
SnnsSnns
Snns
mondalakash2012
Cell size
Cell sizeCell size
Cell size
sbarkanic

Recently uploaded (20)

MLS 208 - UNIT 1- Lecture Notes - ETANDO AYUK - SANU - Secured.pdf
MLS 208 -  UNIT 1-  Lecture Notes - ETANDO AYUK - SANU - Secured.pdfMLS 208 -  UNIT 1-  Lecture Notes - ETANDO AYUK - SANU - Secured.pdf
MLS 208 - UNIT 1- Lecture Notes - ETANDO AYUK - SANU - Secured.pdf
Eswatini Medical Christian University - EMCU / Southern Nazarene University - SANU
4. Cardiac cycle.pptx cardiovascular system
4. Cardiac cycle.pptx cardiovascular system4. Cardiac cycle.pptx cardiovascular system
4. Cardiac cycle.pptx cardiovascular system
Pooja Rani
patho neuro block 3 QUESTION AANSWER PDF
patho neuro block 3 QUESTION AANSWER PDFpatho neuro block 3 QUESTION AANSWER PDF
patho neuro block 3 QUESTION AANSWER PDF
HariPrashadL
Acute & Chronic Inflammation, Chemical mediators in Inflammation and Wound he...
Acute & Chronic Inflammation, Chemical mediators in Inflammation and Wound he...Acute & Chronic Inflammation, Chemical mediators in Inflammation and Wound he...
Acute & Chronic Inflammation, Chemical mediators in Inflammation and Wound he...
Ganapathi Vankudoth
ALookInsideProvidenceResearchBiobanks.pdf
ALookInsideProvidenceResearchBiobanks.pdfALookInsideProvidenceResearchBiobanks.pdf
ALookInsideProvidenceResearchBiobanks.pdf
tiffanyecchang
PRODUCTION OF HB VACCINE AND INTERFERONS BY rDNA - Copy.pptx
PRODUCTION OF HB VACCINE AND INTERFERONS BY rDNA - Copy.pptxPRODUCTION OF HB VACCINE AND INTERFERONS BY rDNA - Copy.pptx
PRODUCTION OF HB VACCINE AND INTERFERONS BY rDNA - Copy.pptx
karishmaduhijod1
One Health Rabies Control in Indonesia_APCAT meeting May 2022.pptx
One Health Rabies Control in Indonesia_APCAT meeting May 2022.pptxOne Health Rabies Control in Indonesia_APCAT meeting May 2022.pptx
One Health Rabies Control in Indonesia_APCAT meeting May 2022.pptx
Wahid Husein
Multimodal Approaches to Clitoral Augmentation for FGM (PRP _ filler)"
Multimodal Approaches to Clitoral Augmentation for FGM (PRP _ filler)"Multimodal Approaches to Clitoral Augmentation for FGM (PRP _ filler)"
Multimodal Approaches to Clitoral Augmentation for FGM (PRP _ filler)"
Rehab Aboshama
4-PuroKalusugasan 2025 DM 2025-0024.pptx
4-PuroKalusugasan 2025 DM 2025-0024.pptx4-PuroKalusugasan 2025 DM 2025-0024.pptx
4-PuroKalusugasan 2025 DM 2025-0024.pptx
NashiedaLilangBuale
legal Rights of individual, children and women.pptx
legal Rights of individual, children and women.pptxlegal Rights of individual, children and women.pptx
legal Rights of individual, children and women.pptx
Rishika Rawat
Details Study of Haemorrhage Modern & Ayurveda
Details Study of Haemorrhage Modern & AyurvedaDetails Study of Haemorrhage Modern & Ayurveda
Details Study of Haemorrhage Modern & Ayurveda
RaviAnand201252
FAO's Support Rabies Control in Bali_Jul22.pptx
FAO's Support Rabies Control in Bali_Jul22.pptxFAO's Support Rabies Control in Bali_Jul22.pptx
FAO's Support Rabies Control in Bali_Jul22.pptx
Wahid Husein
PERSONALITY DEVELOPMENT & DEFENSE MECHANISMS.pptxPersonality and environment:...
PERSONALITY DEVELOPMENT & DEFENSE MECHANISMS.pptxPersonality and environment:...PERSONALITY DEVELOPMENT & DEFENSE MECHANISMS.pptxPersonality and environment:...
PERSONALITY DEVELOPMENT & DEFENSE MECHANISMS.pptxPersonality and environment:...
ABHAY INSTITUTION
DIAGNOSIS OF PREGNANCY PPT IN ALL TRIMESTER
DIAGNOSIS OF PREGNANCY PPT IN ALL TRIMESTERDIAGNOSIS OF PREGNANCY PPT IN ALL TRIMESTER
DIAGNOSIS OF PREGNANCY PPT IN ALL TRIMESTER
daminipatel37
Eye assessment in polytrauma for undergraduates.pptx
Eye assessment in polytrauma for undergraduates.pptxEye assessment in polytrauma for undergraduates.pptx
Eye assessment in polytrauma for undergraduates.pptx
KafrELShiekh University
Renal Physiology - Regulation of GFR and RBF
Renal Physiology - Regulation of GFR and RBFRenal Physiology - Regulation of GFR and RBF
Renal Physiology - Regulation of GFR and RBF
MedicoseAcademics
IMMUNO-ONCOLOGY DESCOVERING THE IMPORTANCE OF CLINICAL IMUNOLOGY IN MEDICINE
IMMUNO-ONCOLOGY  DESCOVERING THE IMPORTANCE OF CLINICAL IMUNOLOGY IN MEDICINEIMMUNO-ONCOLOGY  DESCOVERING THE IMPORTANCE OF CLINICAL IMUNOLOGY IN MEDICINE
IMMUNO-ONCOLOGY DESCOVERING THE IMPORTANCE OF CLINICAL IMUNOLOGY IN MEDICINE
RelianceNwosu
SAPIENT Medi-trivia Quiz (FINALS) | TRI-ORTA 2025
SAPIENT Medi-trivia Quiz (FINALS) | TRI-ORTA 2025SAPIENT Medi-trivia Quiz (FINALS) | TRI-ORTA 2025
SAPIENT Medi-trivia Quiz (FINALS) | TRI-ORTA 2025
Dr. Anindya
Presentaci坦 "Projecte Benestar". MWC 2025
Presentaci坦 "Projecte Benestar". MWC 2025Presentaci坦 "Projecte Benestar". MWC 2025
Presentaci坦 "Projecte Benestar". MWC 2025
Badalona Serveis Assistencials
Creatines Untold Story and How 30-Year-Old Lessons Can Shape the Future
Creatines Untold Story and How 30-Year-Old Lessons Can Shape the FutureCreatines Untold Story and How 30-Year-Old Lessons Can Shape the Future
Creatines Untold Story and How 30-Year-Old Lessons Can Shape the Future
Steve Jennings
4. Cardiac cycle.pptx cardiovascular system
4. Cardiac cycle.pptx cardiovascular system4. Cardiac cycle.pptx cardiovascular system
4. Cardiac cycle.pptx cardiovascular system
Pooja Rani
patho neuro block 3 QUESTION AANSWER PDF
patho neuro block 3 QUESTION AANSWER PDFpatho neuro block 3 QUESTION AANSWER PDF
patho neuro block 3 QUESTION AANSWER PDF
HariPrashadL
Acute & Chronic Inflammation, Chemical mediators in Inflammation and Wound he...
Acute & Chronic Inflammation, Chemical mediators in Inflammation and Wound he...Acute & Chronic Inflammation, Chemical mediators in Inflammation and Wound he...
Acute & Chronic Inflammation, Chemical mediators in Inflammation and Wound he...
Ganapathi Vankudoth
ALookInsideProvidenceResearchBiobanks.pdf
ALookInsideProvidenceResearchBiobanks.pdfALookInsideProvidenceResearchBiobanks.pdf
ALookInsideProvidenceResearchBiobanks.pdf
tiffanyecchang
PRODUCTION OF HB VACCINE AND INTERFERONS BY rDNA - Copy.pptx
PRODUCTION OF HB VACCINE AND INTERFERONS BY rDNA - Copy.pptxPRODUCTION OF HB VACCINE AND INTERFERONS BY rDNA - Copy.pptx
PRODUCTION OF HB VACCINE AND INTERFERONS BY rDNA - Copy.pptx
karishmaduhijod1
One Health Rabies Control in Indonesia_APCAT meeting May 2022.pptx
One Health Rabies Control in Indonesia_APCAT meeting May 2022.pptxOne Health Rabies Control in Indonesia_APCAT meeting May 2022.pptx
One Health Rabies Control in Indonesia_APCAT meeting May 2022.pptx
Wahid Husein
Multimodal Approaches to Clitoral Augmentation for FGM (PRP _ filler)"
Multimodal Approaches to Clitoral Augmentation for FGM (PRP _ filler)"Multimodal Approaches to Clitoral Augmentation for FGM (PRP _ filler)"
Multimodal Approaches to Clitoral Augmentation for FGM (PRP _ filler)"
Rehab Aboshama
4-PuroKalusugasan 2025 DM 2025-0024.pptx
4-PuroKalusugasan 2025 DM 2025-0024.pptx4-PuroKalusugasan 2025 DM 2025-0024.pptx
4-PuroKalusugasan 2025 DM 2025-0024.pptx
NashiedaLilangBuale
legal Rights of individual, children and women.pptx
legal Rights of individual, children and women.pptxlegal Rights of individual, children and women.pptx
legal Rights of individual, children and women.pptx
Rishika Rawat
Details Study of Haemorrhage Modern & Ayurveda
Details Study of Haemorrhage Modern & AyurvedaDetails Study of Haemorrhage Modern & Ayurveda
Details Study of Haemorrhage Modern & Ayurveda
RaviAnand201252
FAO's Support Rabies Control in Bali_Jul22.pptx
FAO's Support Rabies Control in Bali_Jul22.pptxFAO's Support Rabies Control in Bali_Jul22.pptx
FAO's Support Rabies Control in Bali_Jul22.pptx
Wahid Husein
PERSONALITY DEVELOPMENT & DEFENSE MECHANISMS.pptxPersonality and environment:...
PERSONALITY DEVELOPMENT & DEFENSE MECHANISMS.pptxPersonality and environment:...PERSONALITY DEVELOPMENT & DEFENSE MECHANISMS.pptxPersonality and environment:...
PERSONALITY DEVELOPMENT & DEFENSE MECHANISMS.pptxPersonality and environment:...
ABHAY INSTITUTION
DIAGNOSIS OF PREGNANCY PPT IN ALL TRIMESTER
DIAGNOSIS OF PREGNANCY PPT IN ALL TRIMESTERDIAGNOSIS OF PREGNANCY PPT IN ALL TRIMESTER
DIAGNOSIS OF PREGNANCY PPT IN ALL TRIMESTER
daminipatel37
Eye assessment in polytrauma for undergraduates.pptx
Eye assessment in polytrauma for undergraduates.pptxEye assessment in polytrauma for undergraduates.pptx
Eye assessment in polytrauma for undergraduates.pptx
KafrELShiekh University
Renal Physiology - Regulation of GFR and RBF
Renal Physiology - Regulation of GFR and RBFRenal Physiology - Regulation of GFR and RBF
Renal Physiology - Regulation of GFR and RBF
MedicoseAcademics
IMMUNO-ONCOLOGY DESCOVERING THE IMPORTANCE OF CLINICAL IMUNOLOGY IN MEDICINE
IMMUNO-ONCOLOGY  DESCOVERING THE IMPORTANCE OF CLINICAL IMUNOLOGY IN MEDICINEIMMUNO-ONCOLOGY  DESCOVERING THE IMPORTANCE OF CLINICAL IMUNOLOGY IN MEDICINE
IMMUNO-ONCOLOGY DESCOVERING THE IMPORTANCE OF CLINICAL IMUNOLOGY IN MEDICINE
RelianceNwosu
SAPIENT Medi-trivia Quiz (FINALS) | TRI-ORTA 2025
SAPIENT Medi-trivia Quiz (FINALS) | TRI-ORTA 2025SAPIENT Medi-trivia Quiz (FINALS) | TRI-ORTA 2025
SAPIENT Medi-trivia Quiz (FINALS) | TRI-ORTA 2025
Dr. Anindya
Creatines Untold Story and How 30-Year-Old Lessons Can Shape the Future
Creatines Untold Story and How 30-Year-Old Lessons Can Shape the FutureCreatines Untold Story and How 30-Year-Old Lessons Can Shape the Future
Creatines Untold Story and How 30-Year-Old Lessons Can Shape the Future
Steve Jennings

How To Talk About ASEA By Dr. Gary Samuelson, PhD