Mobile phone data from carriers like Sprint and Verizon can be used to derive 24/7 operational origin-destination (OD) matrices showing travel patterns. A pilot study in Sacramento used encrypted Sprint data to identify over 280,000 trips which were mapped to traffic analysis zones to generate hourly OD matrices. These matrices were refined using traffic assignment and counts with results having R-squared values over 0.85. Further research opportunities exist to analyze trip modes, activity chains, and travel behavior changes over time using continuous mobile phone data observations.