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We are passionate about redefining youth through our revolutionary products and lifechanging opportunities. We are bringing people together under the simple idea that everyone deserves a chance to live a youthful, healthy life and discover financial freedom.
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Malaria is a life-threatening disease. Its typically transmitted through the bite of an infected Anopheles mosquito. Infected mosquitoes carry the Plasmodium parasite. When this mosquito bites you, the parasite is released into your blood stream.
Phylum : Protozoa
Subphylum : Apicomplexa (Sporozoa)
Class : Telosporea
Genus : Plasmodium
Species : vivax
Plasmodium is one of the most harmful parasites of man.
It is a digenetic, intracellular parasite that lives in the liver cells and RBC of man. (It is extracellular in mosquito).
Its primary host is the female Anopheles mosquito and the secondary host is man. Reservoir host is monkey.
The infective stage is sickle shaped sporozoite and the mode of infection is inoculation.
Four species of Plasmodium cause four types of malaria in man.
They are
i) Plasmodium vivax benign tertian malaria
ii) Plasmodium falciparum malignant tertian malaria
iii) Plasmodium ovale mild tertian malaria
iv) Plasmodium malariae quartan malaria
Of all these four species, Plasmodium vivax is the most common and most widely distributed malaria parasite.
OBJECTIVES AND USE OF ANTIMALARIAL DRUGS
The aims of using drugs in relation to malarial infection are:
(i) To prevent clinical attack of malaria (prophylactic).
(ii) To treat clinical attack of malaria (clinical curative).
(iii) To completely eradicate the parasite from the patients body (radical curative).
(iv) To cutdown human-to-mosquito transmission (gametocidal).
These are achieved by attacking the parasite at its various stages of life cycle in the human host .
Antimalarials that act on erythrocytic schizogony are called erythrocytic schizontocides
Antimalarials that act on pre erythrocytic as well as exoerythrocytic (P. vivax) stages in liver are called tissue schizontocides,
Antimalarials which kill gametocytes in blood are called gametocides.
Severe and complicated falciparum malaria
This includes P. falciparum infection attended by any one or more of
Hyperparasitaemia,
Hyperpyrexia,
Fluid and electrolyte imbalance,
Acidosis,
Hypoglycaemia,
Prostration,
Cardiovascular collapse,
Jaundice,
Severe anaemia,
Spontaneous bleeding,
Pulmonary edema,
Haemoglobinuria,
Black water fever,
Renal failure
Cerebral malaria.
Artesunate: 2.4 mg/kg i.v. or i.m., followed by 2.4 mg/kg after 12 and 24 hours, and then once daily for 7 days. Switchover to 3 day oral ACT in between whenever the patient can take and tolerate oral medication.
or
Artemether: 3.2 mg/kg i.m. on the 1st day, followed by 1.6 mg/kg daily for 7 days. Switchover to 3 day oral ACT in between whenever the patient is able to take oral medication.
or
Arteether: 3.2 mg/kg i.m. on the 1st day, followed by 1.6 mg/kg daily for the next 4 days. Switchover to 3 day oral ACT inbetween whenever the patient is able to take oral medication.
or
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In an era where global health trends are constantly evolving, Tran Quoc Bao has emerged as a key figure in shaping the future of healthcarestarting with his groundbreaking speech at the prestigious Marina Bay Sands in Singapore. Bao, the visionary leader behind Cao Thang Eye Hospital, made history as the first Vietnamese to speak on healthcare at such a renowned international platform, showcasing the innovation and progress of Vietnamese medical care on a global stage.
Cao Thang Eye Hospital, established under Baos leadership, has long been a trailblazer in ophthalmology, revolutionizing eye care in Vietnam. But its his recent address at Marina Bay Sands that truly underscores the expanding influence of Vietnamese healthcare. The event, which brought together some of the brightest minds in the medical field, provided Bao with an opportunity to not only highlight the advancements in eye care but also demonstrate the rising prominence of Vietnam in the global healthcare landscape.
Healthcare is about more than just treatment; its about creating a sustainable, accessible future for patients, wherever they are in the world, said Bao during his speech. This message resonated deeply, as Bao spoke of his commitment to improving medical access and outcomes in Vietnam, while also emphasizing the importance of collaboration and knowledge-sharing on a global scale.
Under Baos leadership, Cao Thang Eye Hospital has become a beacon of excellence, known for its state-of-the-art treatments and dedication to patient-centered care. From advanced LASIK surgeries to comprehensive eye health check-ups, the hospital has continually raised the bar in Vietnamese ophthalmology. More than just a medical facility, Cao Thang has become a symbol of trust and innovation in the region.
But Baos vision stretches beyond Vietnams borders. His speech at Marina Bay Sands was not just a personal milestone but a significant moment for Vietnamese healthcare, signaling that the country is ready to take its place among global leaders in medical care. Baos approach combines cutting-edge technology with an unwavering commitment to patient well-being, positioning Vietnam as a growing hub for high-quality medical services in Southeast Asia.
Cao Thang Eye Hospitals international recognition is a testament to the growing global respect for Vietnams healthcare sector. Baos work continues to inspire those within the medical community, demonstrating how local expertise can contribute to global conversations about health, innovation, and patient care.
As Baos vision continues to unfold, one thing is clear: Tran Quoc Bao and Cao Thang Eye Hospital are leading Vietnams healthcare revolutionproving that the future of medicine is not just about technology, but about connecting the world through compassionate, accessible, and transformative care.Brain stroke: Symptoms, Classification, prevention and management .pptx
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DISORDERS OF CARDIOVASCULAR SYSTEM
HYPERTENSION
1. Hypertension is defined as persistently elevated arterial blood pressure (BP).
2. Hypertension, also known as high blood pressure, is a chronic medical condition in which the force of blood against the artery walls is consistently too high, increasing the risk of heart disease, stroke, and other health complications.
3. WHO Definition of Hypertension
a. According to the World Health Organization (WHO), hypertension is defined as:
Systolic Blood Pressure (SBP) 140 mmHg
Diastolic Blood Pressure (DBP) 90 mmHg
b. Based on repeated measurements under standardized conditions.
Risk factors
Obesity A sedentary lifestyle
Diabetes mellitus High intakes of salt or alcohol
Family history Stress
Cigarette smoking Low birth weight
Hypertension is described as essential (primary, idiopathic) or secondary to other diseases.
Irrespective of the cause, hypertension commonly affects the kidneys.
Essential hypertension
1. A condition of persistently elevated blood pressure without a known secondary cause, often associated with genetic predisposition and lifestyle factors.
Benign (chronic) hypertension
1. The rise in blood pressure is usually slight to moderate and continues to rise slowly over many years.
2. Sometimes complications, such as heart failure, cerebrovascular accident or myocardial infarction are the first indication of hypertension, but often the condition is symptomless and is only discovered during a routine examination.
Malignant (accelerated) hypertension
1. This is a rapid and aggressive acceleration of hypertensive disease.
2. Diastolic pressure in excess of 120 mmHg is common.
3. The effects are serious and quickly become apparent, e.g. haemorrhages into the retina, papilloedema (oedema around the optic disc), encephalopathy (cerebral oedema) and progressive renal disease, leading to cardiac failure.
Secondary hypertension
Hypertension resulting from other diseases accounts for 5% of all cases.
I. Kidney disease
Raised blood pressure is a complication of many kidney diseases. In kidney disease, there is salt and water retention, sometimes with excessive renin activity.
II. Endocrine disorders
a) Adrenal cortex
Secretion of excess aldosterone and cortisol stimulates the retention of excess sodium and water by the kidneys, raising the blood volume and pressure.
b) Adrenal medulla
Secretion of excess adrenaline (epinephrine) and noradrenaline (norepinephrine) raises blood pressure, e.g. phaeochromocytoma .
III. Stricture of the aorta
Hypertension develops in branching arteries proximal to the site of a stricture, e.g congenital
coarctation.
IV. Drug treatment
Hypertension may be a side-effect of some drugs, e.g. corticosteroids and oral contraceptives.
Effects and complications of hypertension
The effects of long-standing and progressively rising blood pressure are serious.
Hypertension predisposes to atherosclerosis and has specific effects on particular organs.
Heart
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