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Non_Neoplastic_Bowel_Diseases.pptx. H. H nj
- 1. Non-Neoplastic Bowel Diseases Clinical Signs, Diagnosis, and Treatment
- 2. Introduction - Non-neoplastic bowel diseases include inflammatory, infectious, and functional disorders not related to tumor growth. - Common conditions with significant morbidity. - Examples: - Inflammatory Bowel Disease (IBD): Crohns disease, Ulcerative colitis - Irritable Bowel Syndrome (IBS) - Diverticular Disease
- 3. Classification of Non-Neoplastic Bowel Diseases - **Inflammatory Disorders**: Ulcerative colitis, Crohn's disease - **Functional Disorders**: IBS - **Infectious Diseases**: Bacterial, viral, parasitic infections - **Vascular Disorders**: Ischemic bowel disease - **Others**: Diverticular disease, microscopic colitis
- 4. Clinical Signs and Symptoms - **General Symptoms**: - Abdominal pain - Diarrhea (watery, bloody) - Constipation - Bloating and flatulence - Weight loss and fatigue - **Condition-Specific Symptoms**: - Ulcerative Colitis: Rectal bleeding, urgency,
- 5. Diagnostic Methods (Laboratory) - **Blood Tests**: - Complete Blood Count (CBC): Anemia, leukocytosis - CRP, ESR: Inflammation markers - Serologic markers: p-ANCA (Ulcerative Colitis), ASCA (Crohns Disease) - **Stool Tests**: - Stool cultures for infections
- 6. Diagnostic Methods (Instrumental) - **Endoscopy**: - Colonoscopy: Visualization, biopsy for histopathology - Sigmoidoscopy: Useful for distal bowel assessment - **Imaging Studies**: - CT Enterography: Evaluate small bowel in Crohn's disease
- 7. Treatment Overview - **Conservative**: - Dietary modifications (low-residue diet for IBD, high-fiber for diverticular disease) - Symptom control: Antidiarrheals, laxatives (for IBS) - Antibiotics: Infectious colitis, diverticulitis - **Pharmacological**: - IBD: Aminosalicylates, corticosteroids,
- 8. Surgical Treatment - **Indications**: - Failure of medical therapy - Complications: Strictures, perforation, abscess, severe bleeding - **Procedures**: - Ulcerative Colitis: Colectomy with ileal pouch-anal anastomosis (IPAA) - Crohns Disease: Resection of diseased
- 9. Conclusion - Non-neoplastic bowel diseases have diverse presentations, requiring tailored diagnostic and therapeutic approaches. - Advances in imaging, endoscopy, and biologic therapies have significantly improved outcomes.
- 10. References - Scientific articles, textbooks, or credible sources on non-neoplastic bowel diseases. - Examples: Harrison's Principles of Internal Medicine, UpToDate, PubMed.