This document provides guidance on evaluating and summarizing the potential causes of post-operative chest pain in 3 sentences or less: The most common causes of post-operative chest pain are cardiac, pulmonary, gastric, or musculoskeletal in nature. It is important to take a detailed history regarding the pain's characteristics, aggravating/alleviating factors, and associated symptoms. A thorough physical exam including vital signs, cardiac/pulmonary exam, abdominal exam and extremities can help identify potential etiologies and guide further evaluation or treatment.