Prolactinoma.pptx

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Perempuan berusia 46 tahun datang dengan keluhan menstruasi tidak teratur, lesu, dan keluarnya cairan dari puting susu. Tes menunjukkan prolaktin yang sangat tinggi dan TSH yang tinggi, menunjukkan kemungkinan prolaktinoma sebagai penyebabnya.

Science

PROLACTINOMA
Divisi Endokrin Metabolik Diabetes

Scenario
Seorang perempuan usia 46 tahun datang dengan keluhan menstruasi yang tidak teratur , lesu, dan perubahan suasana hati.
juga mengeluhkan keluarnya cairan dari puting susu selama 2 bulan terakhir. Pasien dikenal penderita Hipertensi,mendapat
terapi amlodipine dan doxazosin. Pada pemeriksaan, tes konfrontasi bidang visualnya normal .
Investigations:
◦ FSH : 32 U/L (follicular 0.5–5, midcycle 8–33, luteal 2–8)
◦ LH : 76 U/L (follicular 3–12, midcycle 20–80, luteal 3–16)
◦ Oestradiol : 18 pmol/L (follicular 17–260,luteal 180–1100)
◦ IGF-1 : 34 nmol/L (16–118)
◦ Prolactin : 902 mU/L (45–375)
◦ FT4 : 8.2 pmol/L (11.5–22.7)
◦ TSH : 16.8 mU/L (0.35–5.5)
◦ Urine for pregnancy test : negatif
Manakah dari berikut ini yang merupakan penjelasan yang paling mungkin untuk hiperprolaktinemia dan galaktoreanya?
A. Amlodipin
B. Doxazosin
C. Hipotoroid
D. Prolatiktinomaa
E. Menopause

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Prolactinoma.pptx

1. PROLACTINOMA Divisi Endokrin Metabolik Diabetes

2. Scenario Seorang perempuan usia 46 tahun datang dengan keluhan menstruasi yang tidak teratur , lesu, dan perubahan suasana hati. juga mengeluhkan keluarnya cairan dari puting susu selama 2 bulan terakhir. Pasien dikenal penderita Hipertensi,mendapat terapi amlodipine dan doxazosin. Pada pemeriksaan, tes konfrontasi bidang visualnya normal . Investigations: ◦ FSH : 32 U/L (follicular 0.5–5, midcycle 8–33, luteal 2–8) ◦ LH : 76 U/L (follicular 3–12, midcycle 20–80, luteal 3–16) ◦ Oestradiol : 18 pmol/L (follicular 17–260,luteal 180–1100) ◦ IGF-1 : 34 nmol/L (16–118) ◦ Prolactin : 902 mU/L (45–375) ◦ FT4 : 8.2 pmol/L (11.5–22.7) ◦ TSH : 16.8 mU/L (0.35–5.5) ◦ Urine for pregnancy test : negatif Manakah dari berikut ini yang merupakan penjelasan yang paling mungkin untuk hiperprolaktinemia dan galaktoreanya? A. Amlodipin B. Doxazosin C. Hipotoroid D. Prolatiktinomaa E. Menopause

3. Answer ◦ d. Prolaktinoma

4. Discussion

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Prolactinoma.pptx

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Prolactinoma.pptx