Blood product transfusiondrtanveeralamkhanThis document discusses blood component transfusion. It defines blood components as any therapeutic substance prepared from human blood, including whole blood, red blood cells, platelets, plasma, cryoprecipitate, and growth factors. It describes how whole blood is separated into components through centrifugation. It provides indications, storage requirements, and dosages for transfusing various blood components in pediatric patients. Potential complications of transfusion like acute reactions, late infections, and iron overload are also summarized. The document concludes with SKMCH&RC transfusion protocols.
Blood transfusionRanjita PallaviThis document provides information about blood transfusion, including guidelines, components, and risks. It discusses:
1) Guidelines from 1988 and 2010 that multiple factors should be considered for red blood cell transfusion based on a patient's clinical status and oxygen needs.
2) Red blood cell transfusion is indicated for symptomatic anemia, life-threatening anemia, or restoring oxygen-carrying capacity after hemorrhage.
3) Potential transfusion reactions include febrile non-hemolytic reactions, acute hemolytic reactions, transfusion-related acute lung injury, and infections like HIV or hepatitis. Careful patient screening and component selection can reduce risks.
Blood transfusion & its component therapykitubhaimbbsThis document discusses blood coagulation and blood transfusions. It covers several key points:
1) Only 30% of countries have nationwide transfusion services, and 80% of the world's population only has access to 20% of safely collected and tested blood.
2) The main indications for blood transfusions are to increase oxygen-carrying capacity and intravascular volume when a patient is hemorrhaging.
3) There are several potential complications from blood transfusions like changes in oxygen transport, coagulopathy, allergic reactions, and hemolytic transfusion reactions. Proper testing and protocols are important to minimize risks.
Blood component therapy part Ianaesthesiology-mgmcriThis document discusses blood transfusion and component therapy. It covers the need for transfusion when there is inadequate oxygen carrying capacity or coagulation proteins. Whole blood can be separated into components like red blood cells, platelets, plasma, and cryoprecipitate to target specific needs. Proper testing and storage of components is covered. Clinical indications and transfusion triggers for different components like packed red blood cells, fresh frozen plasma, cryoprecipitate, and platelets are outlined. Blood sparing strategies like autologous donation and acute normovolaemic hemodilution are also summarized.
blood, blood product, blood transfusionHidayat ShariffThis document discusses blood, blood products, and blood transfusion. It defines blood and its components and functions in transportation, protection, and regulation. Blood products include whole blood, packed red cells, platelets, fresh frozen plasma, and cryoprecipitate. Indications for transfusion of specific products are provided. The document also discusses the maximum surgery blood order schedule, blood transfusion reactions and their management, complications of transfusion, hemovigilance, and important takeaways regarding proper transfusion procedures.
Blood transfusionAashish PariharThis document provides information about blood transfusion, including its definition, purposes, components, blood grouping and cross matching, types of transfusions, general instructions, and complications. Blood transfusion involves collecting blood from a donor and administering it to a recipient. It can be used to treat anemia, restore blood volume after hemorrhaging, and provide antibodies or clotting factors. Blood components include whole blood, packed red blood cells, plasma, platelets, and cryoprecipitate. Cross matching must ensure compatibility of blood types and Rh factor. Potential complications include acute and delayed hemolytic reactions, circulatory overload, and infections.
Safe blood transfusion practices and policy of hospitalLee Oi Wah1) Blood transfusion is generally safe but risks include acute haemolytic transfusion reactions, transfusion-related acute lung injury, allergic reactions, and bacterial contamination.
2) If a transfusion reaction is suspected, the transfusion must be stopped immediately and the patient closely monitored and treated depending on symptoms.
3) Investigations include blood and urine samples, and the transfusion reaction report form must be completed to document the event and aid investigation.
Blood transfusion services qcNc DasThis is the extended post discussing the issues in the Quality and the Risk Management in the field of Blood Transfusion
Guidelines of blood transfusionDr. Mohamed Maged KharabishThis document provides guidelines for blood transfusion and alternatives. It recommends considering alternatives to transfusion such as erythropoietin, intravenous/oral iron, cell salvage, and tranexamic acid for non-bleeding surgery patients. For those requiring transfusion, it provides thresholds and dosing guidelines for red blood cells, platelets, fresh frozen plasma, cryoprecipitate, and prothrombin complex concentrate based on bleeding status and test results. All decisions should consider the full clinical situation to avoid under or over-transfusion.
Blood transfusion●๋•αηкιтα madanThis document discusses blood transfusion and its components. It begins by outlining the characteristics of an ideal blood substitute. It then discusses the principal aims of blood transfusion, including improving oxygen carrying capacity and reducing hypovolaemia. It provides guidance on blood transfusion, including recommendations from WHO and the Council of Europe. It details the process of blood grouping and cross-matching. Finally, it discusses various blood components that can be transfused, including packed red blood cells, platelets, fresh frozen plasma, cryoprecipitate, and granulocyte concentrates, along with their indications, contents, shelf lives, and administration considerations.
Blood transfusion in surgeryDrkabiru2012The document provides an overview of blood transfusion, including donor selection, blood components and their indications, pre-transfusion handling, administration principles, massive transfusion, autologous transfusion, complications and their management, and blood substitutes. Donor selection involves medical history screening and health assessments. Key blood components discussed are packed red blood cells, platelet concentrates, fresh frozen plasma, and cryoprecipitate. Proper storage, grouping, compatibility testing and administration procedures are outlined to ensure safety. Complications can be immediate or delayed, including infections transmitted and reactions to plasma proteins. Blood substitutes under development aim to replace functions of plasma, red cells and platelets.
Blood Transfusion (a nursing procedure) by www.nursesinfosite.blogspot.comLouie RayNEW BLOGSITE ADDRESS:
"Nurses Information Site"
http://nursesinfosite.blogspot.com
Please leave a comment after downloading.
THANK YOU ^^
Wardclass powerpoint blood transfusionKatherine 'Chingboo' LaudThis document defines blood transfusion and outlines its purposes, situations where it is needed, potential reactions, and nursing interventions. It describes blood transfusion as introducing blood products intravenously to replace lost blood or restore oxygen capacity. Common situations requiring transfusion include surgery, injuries, anemia, or bleeding disorders. The document also classifies different blood products like packed red blood cells, plasma, and platelets, and how they are used.
Blood transfusionAashissh ShahThis document discusses blood transfusion, including definitions, types of transfusions, blood products, indications for transfusion, risks, and guidelines. It covers topics like whole blood, packed red blood cells, platelets, plasma, and cryoprecipitate. Key points include that transfusion involves receiving blood products intravenously to replace lost blood, it can use one's own blood or from a donor, and decisions should be based on careful assessment of clinical and lab indications to save life or prevent morbidity.
Guidelines of blood transfusionDr. Mohamed Maged KharabishThis document provides guidelines for blood transfusion and alternatives. It recommends considering alternatives to transfusion such as erythropoietin, intravenous/oral iron, cell salvage, and tranexamic acid for non-bleeding surgery patients. For those requiring transfusion, it provides thresholds and dosing guidelines for red blood cells, platelets, fresh frozen plasma, cryoprecipitate, and prothrombin complex concentrate based on bleeding status and test results. All decisions should consider the full clinical situation to avoid under or over-transfusion.
Blood transfusion●๋•αηкιтα madanThis document discusses blood transfusion and its components. It begins by outlining the characteristics of an ideal blood substitute. It then discusses the principal aims of blood transfusion, including improving oxygen carrying capacity and reducing hypovolaemia. It provides guidance on blood transfusion, including recommendations from WHO and the Council of Europe. It details the process of blood grouping and cross-matching. Finally, it discusses various blood components that can be transfused, including packed red blood cells, platelets, fresh frozen plasma, cryoprecipitate, and granulocyte concentrates, along with their indications, contents, shelf lives, and administration considerations.
Blood transfusion in surgeryDrkabiru2012The document provides an overview of blood transfusion, including donor selection, blood components and their indications, pre-transfusion handling, administration principles, massive transfusion, autologous transfusion, complications and their management, and blood substitutes. Donor selection involves medical history screening and health assessments. Key blood components discussed are packed red blood cells, platelet concentrates, fresh frozen plasma, and cryoprecipitate. Proper storage, grouping, compatibility testing and administration procedures are outlined to ensure safety. Complications can be immediate or delayed, including infections transmitted and reactions to plasma proteins. Blood substitutes under development aim to replace functions of plasma, red cells and platelets.
Blood Transfusion (a nursing procedure) by www.nursesinfosite.blogspot.comLouie RayNEW BLOGSITE ADDRESS:
"Nurses Information Site"
http://nursesinfosite.blogspot.com
Please leave a comment after downloading.
THANK YOU ^^
Wardclass powerpoint blood transfusionKatherine 'Chingboo' LaudThis document defines blood transfusion and outlines its purposes, situations where it is needed, potential reactions, and nursing interventions. It describes blood transfusion as introducing blood products intravenously to replace lost blood or restore oxygen capacity. Common situations requiring transfusion include surgery, injuries, anemia, or bleeding disorders. The document also classifies different blood products like packed red blood cells, plasma, and platelets, and how they are used.
Blood transfusionAashissh ShahThis document discusses blood transfusion, including definitions, types of transfusions, blood products, indications for transfusion, risks, and guidelines. It covers topics like whole blood, packed red blood cells, platelets, plasma, and cryoprecipitate. Key points include that transfusion involves receiving blood products intravenously to replace lost blood, it can use one's own blood or from a donor, and decisions should be based on careful assessment of clinical and lab indications to save life or prevent morbidity.
2. RABDOMİYOLİZ
• Kas hücrelerinin hızlı bir şekilde
yıkılması sonrası kas hem
proteinleri böbreklerde
metobolize edilir ve serbest
radikaller ortaya çıkartır.
• Serbest radikaller ve ortaya
çıkan NO endotel reseptörlerini
uyararak sinerjitik etki
göstererek renal
vazokonstriksiyona ve
intraluminal cast formasyonu
sonrası miyoglibinurik akut
böbrek yetmezliğine yol açar.
3. EPO
• Eritropoetin 20 yıla yakın
zamandır kronik böbrek
yetmezliği ve kanser
kemoterapisi ile ilişkili anemi de
kullanılmaktadır.
• Son yapılan çalışmalarda EPO
nin hematopoetik olmayan
dokularda ki EPO-R reseptorüne
bağlanarak sitoprotektif etkileri
olduğu gösterilmiştir.
4. • (rhEPO) ,nuklear faktor -₭B(NF- ₭B) p65 i
aktive ederek ;aktive makrofajlarda ki nitrik
oksit sentataz ve Tumor nekroziz faktor (TNF)
gibi proinflamatuar genleri inhibe eder.
• Bu sayede pro-inflamatuar sitokin üretimini
engeller.
5. • rh EPO ile yapılan bir çok çalışma mevcuttur.
1. İskemi-reperfüzyon hasarına bağlı böbrek
yetmezliği
2. Sisplatine bağlı ABY de
Faydalı olduğu gösterilmiştir.
6. Bu çalışmada 280-300gr lık 24 tane SpragueDawley sıçan kullanılmıştır.
• Kan almak için femoral arter kateteri, ve kan
örneği almak için femoral ven katateri
takılmışıt.
7. • Sıçanlar üç gruba ayrılmıştır
1. Gliserol grubu
2. Gliserol + EPO grubu
3. Normal salin+EPO grubu
0,1,3,6,9,12,18,24 ve 48.
saatlerde kan örnekleri alınarak
hemoglobin,BUN,Cre,glutamik
oksaloasetik
transaminaz, Glutamik pirüvik
transaminaz ve kreatin
fosfokinaz(CPK) düzeylerine
bakıldı.
48. Saatte böbrekleri alınarak
patoloji ve İHC yapıldı.
8. Sonuçlar
• Gliserol ün IM enjkeksiyonu kan
BUN,Cre,glutamik oksaloasetik
transaminaz, Glutamik pirüvik
transaminaz ve kreatin
fosfokinaz(CPK) düzeylerini
anlamalı olarak yükseltmiştir.
• İHC çalışmalarında böbrek
dokusunda nuklear faktor ₭B(NF- ₭B), nitrik oksit sentataz
ın arttığı ve E-cadherinin azaldığı
gösterilmiştir.
