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FAIZA ASTIANI
1100102/C
Tissue factor-
VIIa
Acute Coronary Syndrome
Electrocardiogram
Non ST-elevation
ST- elevation
Chest Pain
Cardiac Marker:
Troponin I, Troponin T
Unstable anginaMyocardial infarction
Atherosclerosis
Plak pada dinding pecah (Rupture)
Thrombus
Non stabil: Nyeri > 20 menit
Stabil: Nyeri < 10 menit
Erosion: Terkikis, erosi
Va
IXaIX
Jalur Intrinsik
Jalur Ekstrinsik
XIaXI
XIIaXII
Vitamin K (Inaktif)
Vitamin K (aktif)
Vitamin yang membantu pembekuan darah
PositifPositif
NSTEMISTEMI
Platelet Agregation
Conformational activation
of GPIIb/IIIa
Eptifibatide,
Abcisimab, Tirofiban
(GP I)
GPIIb/IIIainhibitor
ADP
Paling kuat
Collagen
Clopidogrel,
Prasugrel,Ticagrelor
P2Y12 inhibitor
Heparin
Tx A2
Aspirin
Fondaparinux/Enoxaparin/Nadroparin
(Fondaparinux plg disukai)
Bivalirudin
Warfarin
Enoxaparin di rekomendasikan saat
Fondaparinux tidak tersedia
Thrombus
Angina:
 CCB
 BB
 Nitrat
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Skema nstemi

  • 1. FAIZA ASTIANI 1100102/C Tissue factor- VIIa Acute Coronary Syndrome Electrocardiogram Non ST-elevation ST- elevation Chest Pain Cardiac Marker: Troponin I, Troponin T Unstable anginaMyocardial infarction Atherosclerosis Plak pada dinding pecah (Rupture) Thrombus Non stabil: Nyeri > 20 menit Stabil: Nyeri < 10 menit Erosion: Terkikis, erosi Va IXaIX Jalur Intrinsik Jalur Ekstrinsik XIaXI XIIaXII Vitamin K (Inaktif) Vitamin K (aktif) Vitamin yang membantu pembekuan darah PositifPositif NSTEMISTEMI Platelet Agregation Conformational activation of GPIIb/IIIa Eptifibatide, Abcisimab, Tirofiban (GP I) GPIIb/IIIainhibitor ADP Paling kuat Collagen Clopidogrel, Prasugrel,Ticagrelor P2Y12 inhibitor Heparin Tx A2 Aspirin Fondaparinux/Enoxaparin/Nadroparin (Fondaparinux plg disukai) Bivalirudin Warfarin Enoxaparin di rekomendasikan saat Fondaparinux tidak tersedia Thrombus Angina: CCB BB Nitrat