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- 1. :????? ?????? ???????? ?"?????? ??????????????? ?????????????? ????????? ????????????????? ???????? ??????? ??????? ????? ????????? "?????????? ?????????? ????????? ???? ????? ?????????????? ?????????????? ????????? ????????? ?????????? ???????? ???? ????? ????????? ????? ?????? ?????????? ??????? ???? ??????? ?????????????? ???????????? ????????? ?????? ????? ???????? ??????? ????? ???????? ??????? ?????? ????????? ?????????? ????????? ????? ?????? ???????? ??????? ?????? ??????? Particular Solutions of the Confluent Hypergeometric Differential Equation by Using the Nabla Fractional Calculus Operator ???????????? ??????? ?????? ????? ????? ????????????????? ????? CHFs . ????? ???????? ???? ???? ??? ??????? ???????? ??????? ?????? ????????? ?????? ????????? ?????????????????????????????????????? Nabla. ???????????????? ??????? ????????????? ???????? ??????????? ????? ??? ??????? :?????? ??????? ??????? ??????? ???? .?????????? ????????? ???? ?????? ???????? ??????? ?????? ?????? ?????????? ???????? ????? ???????? ??????? ?????? ???? ????????? ????? ???? .???????? ???? ???????? ??????? ???????? ????????? ????? ?????? ??????? ?????????? ?????? ???????????? ????????????? ??????? ???? ???????? ???? .??????? ??????????????? ???????? ??????? ????????? ?????? ?????? ????? ???????? ???? ?????? ???????? ????????? ??????? ???? ??????? ????? ????? ?????? ????????? ??????? ?????? ?????? ?????? ??????? ??????? ?????? ????? ???????? ??????? ??????? ????? ???? ?????? ????????? .?????? ????? ????? ????? ????? ???????? ????????? ??????? ??????? ??????? ????? ??????? ???????? ?????? ????????? ??????? ??????? ???? ????????? ?????????? ????????? ??????? ??????? ?????????? ?????????? ????????? ?????? ???????? ????????? ???????? ????? ??????? ????? Circular Dichroism
- 2. :?????????? ?????? ?????????? ??????? ???????? ??????? ??????? ?????????? ??????? ?????? ?????????? " ??????? ??????? ??????????????? ????? ???????? ?"??? ??????? ???????? ?????? ????? ?????????? ??????? ?????? ????????? ?????????? ????????? ??????? ????? ????????? ?????? ??????????????? ????? ???????? ???? ??????????2??????? ?????? .??????? ???????? ??????????? ??? ?????????? ??????? ??????? ??? ??????? ????? ???? ??????????? ??????? ??????? ???????? ?????? ???????? ??????????????????????????? ????? ???????? ???? ????? .???????? ???????? ???????? ????? ??? ???????? ??????? ??????? ???????????????? ??????? ?????? ???? .?????????? ????????? ??????? ?????? ?????????? ???? ????? ???? ??? ????????????????????????? ???????? ???? ?????????83-67??? ??????? ????? ???????? ?????????76-06???? ???????? ????????????? ???????? ???????? ????? ???????? 1/??????????????? ?????: Neuroprotective effect of carnosine and cyclosporine-A against inflammation, apoptosis, and oxidative brain damage after closed head injury in immature rats ??? ???????????? ????????? ?????????????????? ???? ?????? ?????????? ??????? ?,?? ????????? ????????? ????? , ???????????? ???? ??????????????? ??????? ??????? ??????? ????????? ??????? ?????? ??? .????????? ??????? ????????? ????? ???? ???? ????? ????????? ?????????? ??????? ????? ?????? ????????? ?????? ?????? ?????????? ????????? ?????? ??????? ???? ????????? ????????? ?????????? ??? ?????? ??????? ????? ???? ??????? ??????? ???? ????????? ?????????? ???????? ????? ??? ???????????? ?????? ???????? ????? ?????? ?????????? ????? . ???????? ????? ????????? ????????? ????????? ???? ??????????????????????? ????? ???????????????????????????? ???? ???????? ??????????? ???? ??????? ????? ????????? ?????? ????.????????? ????? ????????? ???? ?????????? ????????? ????????? ??????? ?????????????? ??????? ?????????????????????????????? ??????????????????????????? ???????? ????????? ???????? ????????? ???????????????? ????????????????? ?????????????.
- 3. :2 ??????????? ??????? Effect of aliskiren and carvedilol on expression ofCa2+/calmodulin-dependent protein kinase II δ- subunit isoforms in cardiac hypertrophy rat model ??????? ???? ????????? ????? ??????????? ??? ??????????? ??????????????? ???????? ?????? ???????? ??????????? ????????? ??? ??????? ???????? ????????? ??????? ???? ???????????? ??????????? ??????? ?????? ???????? ???????? ?????? ???????? ?????????? ???? ????????? ??????? ???? ?????????? ???? ???????? ??????????????????? ??????????? ????? ????????? ??? .??????? ?????? ????? ??????????????????? ???? ??????? ????? ????????? ?????????? ???????? ???? ???????? ????????? ????? ?????? ???????????? ???????? ???????? ??????????????????? ?????? ?????????? ???????? ???????? ????????? ??????? ???? ???????????? ??????????? ????? ??????????? ???? ????? ???????? ???? ????? ????? .???????????? ?????? ???? ????? ????? ??????? ????????????? ???? ????? ????? ??????? ??????? ????????????? ???? ?????? ???????? ????? ????? ????????????????????? ??????? ?????????????????? ??????? ????????? ????? ???? ???????? ??????? ?????? ?????? ???????? ???????? ?????? ???????? ??????? ??????? ????? ???????????? ?????? ???? ???????????? ??????? ???????????????????? ????? ?????????? ??????? ??????? ????????? ????????? ?????? ?????????? ????????????.
- 4. :?????? ?????? ???: ??????? ??????Simultaneous determination of selectedtyrosine kinase inhibitors with corticosteroids and antiemetics in rat plasma by solid phase extraction and ultra- performance liquid chromatography-tandem mass spectrometry: Application to pharmacokinetic interaction studies This work deals with the development and validation of a sensitive and selective ultra- performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for the simultaneous determination of selected tyrosine kinase inhibitors (TKIs); gefitinib (GEF), erlotinib (ERL), along with corticosteroids (dexamethasone DEX, prednisolone PRED), and the antiemetic ondansetron (OND) in rat plasma samples. Steroids and antiemetics are usually used with GEF/ERL to improve treatment- and disease-related symptoms in patients with cancer. They may affect the cytochrome 3A4 (CYP3A4)-mediated metabolism of the co-administered TKI. Thus, this study is useful to study the possibility of drug-induced interactions that could be encountered following their co-administration. This study can be readily applied in therapeutic drug monitoring (TDM) in patients receiving these drug combinations as well as investigation of possible drug interactions between the cited TKIs and DEX/PRED/OND. ?????? ????????? ????????? ??????? ????? ?????????????????? ??????? ??????????? ????????? ?????????? ????????? ??????????? ??????? ??? )?(????????????? ??????? ??????? ?)?????????????? ?(????????????? ????????????? ????? ???? )??????????? ?(?????????? ????? ???????? ???????? ????? ???????? ??????????????? ????? ??????? ??????? ?????????? ????????? ???????? ??????? ?????????????????? ???? ?????? ???? ??????? ????????? ????????????? ????? ???????? .??????? ???????? ???????????? ?????? ?????? ???? ???????? ???????? ??????? ????????? ????? ?????? ?????????? ????? ??????? .????????? ???????? ?????????? ????????? ???????? ????????????? ?????????? ???????? ????????? ??????? ???? ???????? ???????????????????? ?????????? ??????? ??????? ???? ?????? ????? ?????????? ??????? ????? ?????? ??????? .????????? ?????? ?????? ???? ????????? ????? ?????????? ??????? ??????? ????? ????????? ????? ??????? ???? ????? ? ??????? ???? ????? ????????? ?????????? ???????? ??????????? ?????? ??????? ?????????? ??????????? ???????? ???? ????????? ????? ????????????? ???????? ??????????????? ???? ????????? ?????.