![1999 ASHRAEHVAC [Clean Room Design Criteria]
Handbook
Cleanliness Class
ISO
Class Airflow Type1 Average Airflow Velocity Air Changes Per Hour
M7 & M6.5
(Class 100,000)
8
Nonunidirectional,
mixed
(4-8 fpm)
M6 & M5.5
(Class 10,000)
7
Nonunidirectional,
mixed
(8-15 fpm) As per ISO 14644-1 ,
As per ISO 14644-4,
11 Documents as Clean
Room Standards,
1999 ASHRAE,
USFDA,
ISO 209E
M5 & M4.5
(Class 1,000) 6
Nonunidirectional,
mixed (25-35 fpm)
M4 & M3.5
(Class 100) 5
Unidirectional,
Nonunidirectional,
mixed (40-60 fpm)
M3 & M2.5
(Class 10) 4 Unidirectional (60-70 fpm)
M2 & M1.5
(Class 1) 3 Unidirectional (70-85 fpm)
M1 & Cleaner Unidirectional (85-100 fpm)](https://image.slidesharecdn.com/1bdbbbe9-bb5a-413d-b2f6-de8a99e043bd-160829083430/85/SSV-PPT-20-320.jpg)
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- 20. 1999 ASHRAEHVAC [Clean Room Design Criteria] Handbook Cleanliness Class ISO Class Airflow Type1 Average Airflow Velocity Air Changes Per Hour M7 & M6.5 (Class 100,000) 8 Nonunidirectional, mixed (4-8 fpm) M6 & M5.5 (Class 10,000) 7 Nonunidirectional, mixed (8-15 fpm) As per ISO 14644-1 , As per ISO 14644-4, 11 Documents as Clean Room Standards, 1999 ASHRAE, USFDA, ISO 209E M5 & M4.5 (Class 1,000) 6 Nonunidirectional, mixed (25-35 fpm) M4 & M3.5 (Class 100) 5 Unidirectional, Nonunidirectional, mixed (40-60 fpm) M3 & M2.5 (Class 10) 4 Unidirectional (60-70 fpm) M2 & M1.5 (Class 1) 3 Unidirectional (70-85 fpm) M1 & Cleaner Unidirectional (85-100 fpm)
- 21. Air Filtration system 1999 ASHRAE Handbook Cleanliness Class ISO Class Filter Type Filter Coverage M7 & M6.5 (Class 100,000) 8 HEPA M6 & M5.5 (Class 10,000) 7 HEPA M5 & M4.5 (Class 1,000) 6 HEPA M4 & M3.5 (Class 100) Service corridor 5 HEPA As per ISO 14644-1 , As per ISO 14644-4, 11 Documents as Clean Room Standards, 1999 ASHRAE, USFDA, ISO 209E M4& M3.5 (Class 100) Gown room 5 HEPA M4& M3.5 (Class 100) 5 HEPA M3& M2.5 (Class 10) 4 ULPA M2& M1.5 (Class 1) 3 ULPA
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- 26. Testing & Validation of Clean Rooms Particle test of cleanliness As per ISO 14644 Standards Air Velocity Test Air pattern Smoke Test Light Intensity Test Noise Test Vibration Test Induction Leak Test
- 27. Operations Scheduling Maintenance Planning Monitoring the system Pressure Balancing Room Pressure Analysis Temperature & Humidity Maintenance
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