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STATES OF MATTER & PROPERTIES OF
MATTER
Ms. Punam Dilip Bagad
Assistant Professor, Dept. of Pharmaceutics
GESs Sir Dr. M. S. Gosavi College of Pharm. Edu. & Research,
Nashik-422005, INDIA
1
2
Content as per syllabus
 State of matter, changes in the state of matter,
 Latent heats, vapour pressure, sublimation critical point, eutectic
mixtures,
 Gases, Liquefaction of gases, aerosols inhalers,
 Relative humidity, liquid complexes, liquid crystals, glassy states, solid
crystalline, amorphous(Methods of crystal analysis: X-Ray Diffraction,
Braggs equation)
 Polymorphism (Definition, Different shapes of polymorphs, Example
and its Pharmaceutical applications, Brief introduction of Detection
techniques).
3
STATE OF MATTER
 Matter is the Stuff of the universe- the atoms, molecules and ions that make-
up all physical substances.
 Matter is anything that has mass and takes up space.
 There are 5 known phases or states:
 Solids
 Liquids
 Gases
 Plasma
 Bose-Einstein Condensates
4
STATE OF MATTER
 Solid, liquid, and gases are the three primary states of matter or phases.
 The factors which usually determine the state in which matter exists are
 Intensity of intermolecular forces
 Temperature
 Pressure
 Solids have the strongest intermolecular forces and gases have the weakest.
 As the temperature of solid increased, the molecules acquire sufficient
energy to break the ordered structure and pass into the liquid form.
 On further increasing the temperature, liquid changes to the gaseous state.
5
STATE OF MATTER
 Solid ice, liquid water, water vapor: All 3 states co-exist at the freezing point
of water..
 Solids with high vapor pressures, such as Iodine and Camphor, can pass
directly from the solid to the gaseous state without melting at room
temperature. This process is known as sublimation.
6
Matter
Pure substances
elements
compounds
Mixture of
substances
Heterogeneous
mixtures
Homogeneous
mixtures
7
STATE OF MATTER
 A substance is a form of matter that has a constant composition.
 Physicochemical properties of a substance are dependent on the
organizational arrangement of its constituent atoms.
 Example: n-butane and iso-butane (same chemical formula)
8
Physical properties n-butane iso-butane
Boiling point 0属C
0属C
Melting point
-138属C -159属C
density 0.622 g/ml 0.604 g/ml
9
10
11
Changes in States of Matter
 Molecular interactions: keep the molecules together while the thermal
energy provides motions to the molecules.
 K.E. based on thermal energy and intermolecular interactions based on
pressure.
 These are responsible for intermolecular forces of attraction and decide
physical state of the substance.
 Intermolecular forces are the forces of attraction between neighbouring
molecules.
 Temperature and pressure decides the physical state of the substance.
12
13
STATE OF MATTER
 Changes in the physical state: Changes in the physical state of substance
are reversible in nature
 These are due to rearrangement of the molecules in a substance.
 Changes in the chemical state: Changes in the chemical state are due to
change in specific orientation or arrangement of the atoms and groups of the
substance.
 Changes may be irreversible
 Chemical changes always result in formation of a new compound having
different properties.
14
Measurable properties of gases
 Characteristics of gases:
1) Mass
2) Volume
3) Temperature
4) Pressure
5) Density
6) Diffusion
15
Measurable properties of gases
Mass:
 Each gas molecule has characteristic mass
 Mass of single gas molecule is negligibly small,
 Mass of one mole of gas molecule = 6.022*1023
 Mass unit = gm/kg
Volume:
 Gas occupies entire space available to it.
 Volume of gas is the volume of container in which it is stored.
 Unit : cm3/dm3/mL/L
16
Measurable properties of gases
Pressure:
 It is the force exerted by the gas molecules per unit area on the walls of the
container.
 Pressure measured by using Barometer or Mercury manometers
 Unit: Pascal, N/m2
Density: Mass/Volume
 Unit: Kg/m3
17
Measurable properties of gases
Diffusion:
 The process of mixing of two or more gases to form homogeneous mixture
is called diffusion.
 The rate at which gases diffuse depends on molar mass of gas
 Lighter gases diffuse faster than heavier gases.
 Unit = cm3/s or dm3/s
 $   =
p   
$   
18
Measurable properties of gases
Temperature:
 =
9
5
 + 32
19
Gas Laws
Boyles Law:
 The pressure (P) of a given mass of a gas varies inversely as its volume (V)
at constant temperature.
 
1

PV= K1
Gay- Lussac Law:
Pressure of a given mass of gas varies directly with the temperature at constant
volume.
  


= Constant = K2
20
Gas Laws
Charles Law:
Volume of the given mass of the gas is directly proportional to absolute
temperature at constant pressure.
  
V= K3T
By combining all three equations:
PV=nRT
21

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States of matter - Part 1

  • 1. STATES OF MATTER & PROPERTIES OF MATTER Ms. Punam Dilip Bagad Assistant Professor, Dept. of Pharmaceutics GESs Sir Dr. M. S. Gosavi College of Pharm. Edu. & Research, Nashik-422005, INDIA 1
  • 2. 2
  • 3. Content as per syllabus State of matter, changes in the state of matter, Latent heats, vapour pressure, sublimation critical point, eutectic mixtures, Gases, Liquefaction of gases, aerosols inhalers, Relative humidity, liquid complexes, liquid crystals, glassy states, solid crystalline, amorphous(Methods of crystal analysis: X-Ray Diffraction, Braggs equation) Polymorphism (Definition, Different shapes of polymorphs, Example and its Pharmaceutical applications, Brief introduction of Detection techniques). 3
  • 4. STATE OF MATTER Matter is the Stuff of the universe- the atoms, molecules and ions that make- up all physical substances. Matter is anything that has mass and takes up space. There are 5 known phases or states: Solids Liquids Gases Plasma Bose-Einstein Condensates 4
  • 5. STATE OF MATTER Solid, liquid, and gases are the three primary states of matter or phases. The factors which usually determine the state in which matter exists are Intensity of intermolecular forces Temperature Pressure Solids have the strongest intermolecular forces and gases have the weakest. As the temperature of solid increased, the molecules acquire sufficient energy to break the ordered structure and pass into the liquid form. On further increasing the temperature, liquid changes to the gaseous state. 5
  • 6. STATE OF MATTER Solid ice, liquid water, water vapor: All 3 states co-exist at the freezing point of water.. Solids with high vapor pressures, such as Iodine and Camphor, can pass directly from the solid to the gaseous state without melting at room temperature. This process is known as sublimation. 6
  • 8. STATE OF MATTER A substance is a form of matter that has a constant composition. Physicochemical properties of a substance are dependent on the organizational arrangement of its constituent atoms. Example: n-butane and iso-butane (same chemical formula) 8 Physical properties n-butane iso-butane Boiling point 0属C 0属C Melting point -138属C -159属C density 0.622 g/ml 0.604 g/ml
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  • 12. Changes in States of Matter Molecular interactions: keep the molecules together while the thermal energy provides motions to the molecules. K.E. based on thermal energy and intermolecular interactions based on pressure. These are responsible for intermolecular forces of attraction and decide physical state of the substance. Intermolecular forces are the forces of attraction between neighbouring molecules. Temperature and pressure decides the physical state of the substance. 12
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  • 14. STATE OF MATTER Changes in the physical state: Changes in the physical state of substance are reversible in nature These are due to rearrangement of the molecules in a substance. Changes in the chemical state: Changes in the chemical state are due to change in specific orientation or arrangement of the atoms and groups of the substance. Changes may be irreversible Chemical changes always result in formation of a new compound having different properties. 14
  • 15. Measurable properties of gases Characteristics of gases: 1) Mass 2) Volume 3) Temperature 4) Pressure 5) Density 6) Diffusion 15
  • 16. Measurable properties of gases Mass: Each gas molecule has characteristic mass Mass of single gas molecule is negligibly small, Mass of one mole of gas molecule = 6.022*1023 Mass unit = gm/kg Volume: Gas occupies entire space available to it. Volume of gas is the volume of container in which it is stored. Unit : cm3/dm3/mL/L 16
  • 17. Measurable properties of gases Pressure: It is the force exerted by the gas molecules per unit area on the walls of the container. Pressure measured by using Barometer or Mercury manometers Unit: Pascal, N/m2 Density: Mass/Volume Unit: Kg/m3 17
  • 18. Measurable properties of gases Diffusion: The process of mixing of two or more gases to form homogeneous mixture is called diffusion. The rate at which gases diffuse depends on molar mass of gas Lighter gases diffuse faster than heavier gases. Unit = cm3/s or dm3/s $ = p $ 18
  • 19. Measurable properties of gases Temperature: = 9 5 + 32 19
  • 20. Gas Laws Boyles Law: The pressure (P) of a given mass of a gas varies inversely as its volume (V) at constant temperature. 1 PV= K1 Gay- Lussac Law: Pressure of a given mass of gas varies directly with the temperature at constant volume. = Constant = K2 20
  • 21. Gas Laws Charles Law: Volume of the given mass of the gas is directly proportional to absolute temperature at constant pressure. V= K3T By combining all three equations: PV=nRT 21