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scalability population-size speedup facetwise-model dimensional-model neighborhood-operators single-point-crossover fitness-inheritance facetwise-models optimization efficiency-enhancement structure-prediction adaptive-time-continuation time-utilization genetic-algorithms power-cycles facetwise models surrogates selection convergence-time noise replacement seeding binary selection-pressure chi-ary gas speed-up test-problems chemical-reaction semiempirical-methods ab-initio estimation regression linear-estimation rule-learning machine learning multi-objective pareto-optimal compact-genetic-algorithm sub-structures rts fitness-sharing time-continuation crossover mutation evaluation-relaxation representation building-blocks