際際滷shows by User: cospim / http://www.slideshare.net/images/logo.gif 際際滷shows by User: cospim / Wed, 15 Feb 2017 23:34:42 GMT 際際滷Share feed for 際際滷shows by User: cospim ECMO - beyond protective ventilation /slideshow/ecmo-beyond-protective-ventilation/72205056 ecmo-170215233442
There might be no safe ventilation. Much too often, all there is for us to measure at the bedside are nothing but global indicators of stress/strain, more or less refined. Heterogeneity at the alveolar level-inhomogeneities or stress raisers - render global parameters less useful than previously predicted. In fact, Mead had already stated it through his work on stress distribution at the alveolar level. ECMO (VA ECMO) might be regarded as one other way of decatecholaminization (M.Singer). Stop stressing the already stressed heart. Unfortunately, fem-fem VA ECMO still needs inotropic support to lessen the LV distension. Levosimendan and IABP combined could help decrease the catecholamine usage in this context.]]>

There might be no safe ventilation. Much too often, all there is for us to measure at the bedside are nothing but global indicators of stress/strain, more or less refined. Heterogeneity at the alveolar level-inhomogeneities or stress raisers - render global parameters less useful than previously predicted. In fact, Mead had already stated it through his work on stress distribution at the alveolar level. ECMO (VA ECMO) might be regarded as one other way of decatecholaminization (M.Singer). Stop stressing the already stressed heart. Unfortunately, fem-fem VA ECMO still needs inotropic support to lessen the LV distension. Levosimendan and IABP combined could help decrease the catecholamine usage in this context.]]>
Wed, 15 Feb 2017 23:34:42 GMT /slideshow/ecmo-beyond-protective-ventilation/72205056 cospim@slideshare.net(cospim) ECMO - beyond protective ventilation cospim There might be no safe ventilation. Much too often, all there is for us to measure at the bedside are nothing but global indicators of stress/strain, more or less refined. Heterogeneity at the alveolar level-inhomogeneities or stress raisers - render global parameters less useful than previously predicted. In fact, Mead had already stated it through his work on stress distribution at the alveolar level. ECMO (VA ECMO) might be regarded as one other way of decatecholaminization (M.Singer). Stop stressing the already stressed heart. Unfortunately, fem-fem VA ECMO still needs inotropic support to lessen the LV distension. Levosimendan and IABP combined could help decrease the catecholamine usage in this context. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/ecmo-170215233442-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> There might be no safe ventilation. Much too often, all there is for us to measure at the bedside are nothing but global indicators of stress/strain, more or less refined. Heterogeneity at the alveolar level-inhomogeneities or stress raisers - render global parameters less useful than previously predicted. In fact, Mead had already stated it through his work on stress distribution at the alveolar level. ECMO (VA ECMO) might be regarded as one other way of decatecholaminization (M.Singer). Stop stressing the already stressed heart. Unfortunately, fem-fem VA ECMO still needs inotropic support to lessen the LV distension. Levosimendan and IABP combined could help decrease the catecholamine usage in this context.
ECMO - beyond protective ventilation from Cosmin Balan
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Quantitative approach in dysnatremias /slideshow/quantitative-approach-in-dysnatremias-55664803/55664803 quantitativeapproachindysnatremias-151130183615-lva1-app6892
Edelman-derived quantification of dyselectrolytemias. Equation-based monitoring of hyponatremia therapy with a focus on safely and predictably increasing sodium as per guideline advice using a strategy involving desmopressin administration in severe hyponatremias, especially those patients at risk of becoming overcorrectors. Explanation of risk factors responsible for overshooting when correcting hyponatremia. Adrogue-Madias, Barsoum, Nguyen-Kurtz equations are explained and proven to be of help at least conceptually when attempting to have a desmopressin-guided therapy in hyponatremia. All recommendations are done in accordance with European and American guidelines published in 2013 and 2014.]]>

Edelman-derived quantification of dyselectrolytemias. Equation-based monitoring of hyponatremia therapy with a focus on safely and predictably increasing sodium as per guideline advice using a strategy involving desmopressin administration in severe hyponatremias, especially those patients at risk of becoming overcorrectors. Explanation of risk factors responsible for overshooting when correcting hyponatremia. Adrogue-Madias, Barsoum, Nguyen-Kurtz equations are explained and proven to be of help at least conceptually when attempting to have a desmopressin-guided therapy in hyponatremia. All recommendations are done in accordance with European and American guidelines published in 2013 and 2014.]]>
Mon, 30 Nov 2015 18:36:15 GMT /slideshow/quantitative-approach-in-dysnatremias-55664803/55664803 cospim@slideshare.net(cospim) Quantitative approach in dysnatremias cospim Edelman-derived quantification of dyselectrolytemias. Equation-based monitoring of hyponatremia therapy with a focus on safely and predictably increasing sodium as per guideline advice using a strategy involving desmopressin administration in severe hyponatremias, especially those patients at risk of becoming overcorrectors. Explanation of risk factors responsible for overshooting when correcting hyponatremia. Adrogue-Madias, Barsoum, Nguyen-Kurtz equations are explained and proven to be of help at least conceptually when attempting to have a desmopressin-guided therapy in hyponatremia. All recommendations are done in accordance with European and American guidelines published in 2013 and 2014. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/quantitativeapproachindysnatremias-151130183615-lva1-app6892-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Edelman-derived quantification of dyselectrolytemias. Equation-based monitoring of hyponatremia therapy with a focus on safely and predictably increasing sodium as per guideline advice using a strategy involving desmopressin administration in severe hyponatremias, especially those patients at risk of becoming overcorrectors. Explanation of risk factors responsible for overshooting when correcting hyponatremia. Adrogue-Madias, Barsoum, Nguyen-Kurtz equations are explained and proven to be of help at least conceptually when attempting to have a desmopressin-guided therapy in hyponatremia. All recommendations are done in accordance with European and American guidelines published in 2013 and 2014.
Quantitative approach in dysnatremias from Cosmin Balan
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Alkalinization induced inotropic enhancement /slideshow/alkalinization-induced-inotropic-enhancement/55350375 newmicrosoftpowerpointpresentation-151120203133-lva1-app6891
Buying time in situations of extreme hemodynamic instability by partially reversing acidemia with a controlled strategy involving bicarbonate, calcium and hyperventilation. Minimizing CO2 buildup as well as resulting hypocalcemia after alkalinization improves hemodynamics in a rat-derived french study.]]>

Buying time in situations of extreme hemodynamic instability by partially reversing acidemia with a controlled strategy involving bicarbonate, calcium and hyperventilation. Minimizing CO2 buildup as well as resulting hypocalcemia after alkalinization improves hemodynamics in a rat-derived french study.]]>
Fri, 20 Nov 2015 20:31:33 GMT /slideshow/alkalinization-induced-inotropic-enhancement/55350375 cospim@slideshare.net(cospim) Alkalinization induced inotropic enhancement cospim Buying time in situations of extreme hemodynamic instability by partially reversing acidemia with a controlled strategy involving bicarbonate, calcium and hyperventilation. Minimizing CO2 buildup as well as resulting hypocalcemia after alkalinization improves hemodynamics in a rat-derived french study. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/newmicrosoftpowerpointpresentation-151120203133-lva1-app6891-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Buying time in situations of extreme hemodynamic instability by partially reversing acidemia with a controlled strategy involving bicarbonate, calcium and hyperventilation. Minimizing CO2 buildup as well as resulting hypocalcemia after alkalinization improves hemodynamics in a rat-derived french study.
Alkalinization induced inotropic enhancement from Cosmin Balan
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Math modelled approach to gas-exchange monitoring /slideshow/math-modelled-approach-to-gasexchange-monitoring/52690446 math-modeledapproachtogas-exchangemonitoringautosaved-copy-150912003142-lva1-app6892
mathematical modelled approach to gas exchange monitoring. overview of one parameter models and description of Sapsford and Kjaergaard's two parameter models.computer algorithm in assessing gas exchange at the bedside in a MIGET fashion. prediction of hypoxemia and full description of gas exchange through models that fit perfectly to patient data.]]>

mathematical modelled approach to gas exchange monitoring. overview of one parameter models and description of Sapsford and Kjaergaard's two parameter models.computer algorithm in assessing gas exchange at the bedside in a MIGET fashion. prediction of hypoxemia and full description of gas exchange through models that fit perfectly to patient data.]]>
Sat, 12 Sep 2015 00:31:42 GMT /slideshow/math-modelled-approach-to-gasexchange-monitoring/52690446 cospim@slideshare.net(cospim) Math modelled approach to gas-exchange monitoring cospim mathematical modelled approach to gas exchange monitoring. overview of one parameter models and description of Sapsford and Kjaergaard's two parameter models.computer algorithm in assessing gas exchange at the bedside in a MIGET fashion. prediction of hypoxemia and full description of gas exchange through models that fit perfectly to patient data. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/math-modeledapproachtogas-exchangemonitoringautosaved-copy-150912003142-lva1-app6892-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> mathematical modelled approach to gas exchange monitoring. overview of one parameter models and description of Sapsford and Kjaergaard&#39;s two parameter models.computer algorithm in assessing gas exchange at the bedside in a MIGET fashion. prediction of hypoxemia and full description of gas exchange through models that fit perfectly to patient data.
Math modelled approach to gas-exchange monitoring from Cosmin Balan
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Inhalational Anaesthetics Induced Cardioprotection /slideshow/inhalational-anaesthetics-induced-cardioprotection/49745586 sevoraneandcardioprotection-150623170209-lva1-app6892
we are teleologically cardioprotected. we are already cardioprotected. nature has given us everything we need to be unbreakable.we just have to push the right buttons. please, pay heed to the turtles! they know best!]]>

we are teleologically cardioprotected. we are already cardioprotected. nature has given us everything we need to be unbreakable.we just have to push the right buttons. please, pay heed to the turtles! they know best!]]>
Tue, 23 Jun 2015 17:02:09 GMT /slideshow/inhalational-anaesthetics-induced-cardioprotection/49745586 cospim@slideshare.net(cospim) Inhalational Anaesthetics Induced Cardioprotection cospim we are teleologically cardioprotected. we are already cardioprotected. nature has given us everything we need to be unbreakable.we just have to push the right buttons. please, pay heed to the turtles! they know best! <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/sevoraneandcardioprotection-150623170209-lva1-app6892-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> we are teleologically cardioprotected. we are already cardioprotected. nature has given us everything we need to be unbreakable.we just have to push the right buttons. please, pay heed to the turtles! they know best!
Inhalational Anaesthetics Induced Cardioprotection from Cosmin Balan
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Hemodynamics - paradigm shifts /slideshow/hemodynamics-paradigm-shifts/40611685 partea2hemodinamica-141022160320-conversion-gate02
Paradigms have been shifting. Flow-centered ideas, ventriculo-arterial coupling and redistributions between compartments with different time constants.]]>

Paradigms have been shifting. Flow-centered ideas, ventriculo-arterial coupling and redistributions between compartments with different time constants.]]>
Wed, 22 Oct 2014 16:03:19 GMT /slideshow/hemodynamics-paradigm-shifts/40611685 cospim@slideshare.net(cospim) Hemodynamics - paradigm shifts cospim Paradigms have been shifting. Flow-centered ideas, ventriculo-arterial coupling and redistributions between compartments with different time constants. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/partea2hemodinamica-141022160320-conversion-gate02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> Paradigms have been shifting. Flow-centered ideas, ventriculo-arterial coupling and redistributions between compartments with different time constants.
Hemodynamics - paradigm shifts from Cosmin Balan
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ARDS - principles of mechanical ventilation /slideshow/ards-principles-of-mechanical-ventilation/39540220 remodificataventilatieorgcosmin30-140925164648-phpapp02
ARDS - overview of principles]]>

ARDS - overview of principles]]>
Thu, 25 Sep 2014 16:46:48 GMT /slideshow/ards-principles-of-mechanical-ventilation/39540220 cospim@slideshare.net(cospim) ARDS - principles of mechanical ventilation cospim ARDS - overview of principles <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/remodificataventilatieorgcosmin30-140925164648-phpapp02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> ARDS - overview of principles
ARDS - principles of mechanical ventilation from Cosmin Balan
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Ttp shu /slideshow/ttp-shu/39539860 ttp-shu-140925163341-phpapp01
TTP-HUS Thrombotic microangiopathy is marker for TTP/HUS as well as for DIC/DIC-like (secondary thrombotic microangiopathy-TMA), this giving us a first overlapping area. ADAMTS 13 (ADAMTS 13 Ab/ADAMTS 13 relative or absolute deficiency) - a recent marker for TTP, regulatory complement factors flaws (CFH, MCP-CD46, IF and CD46 Ab, CFH Ab as well)-pathogenetic elements in D- HUS, increased PAI 1-recently proved for TTP, all of this are nowadays valid pathogenetic lego bricks in that wall we call secondary TMA, this giving us our second overlapping area. Plasma exchange, grade IA recommendation for true TTP, has been gaining a place in the last decade in the supportive basket for secondary TMA(e.g., sepsis ), this giving us a third overlapping area. At least three overlapping areas and the lack of certain particular cases (malignant hypertension, HCT related TMA, D+ HUS early years) deliver us a syndrome (TMA) likely to be highly responsive to plasma exchange and, in certain situations, to tailored corticotherapy, monoclonal CD20 Ab, C5 Ab.]]>

TTP-HUS Thrombotic microangiopathy is marker for TTP/HUS as well as for DIC/DIC-like (secondary thrombotic microangiopathy-TMA), this giving us a first overlapping area. ADAMTS 13 (ADAMTS 13 Ab/ADAMTS 13 relative or absolute deficiency) - a recent marker for TTP, regulatory complement factors flaws (CFH, MCP-CD46, IF and CD46 Ab, CFH Ab as well)-pathogenetic elements in D- HUS, increased PAI 1-recently proved for TTP, all of this are nowadays valid pathogenetic lego bricks in that wall we call secondary TMA, this giving us our second overlapping area. Plasma exchange, grade IA recommendation for true TTP, has been gaining a place in the last decade in the supportive basket for secondary TMA(e.g., sepsis ), this giving us a third overlapping area. At least three overlapping areas and the lack of certain particular cases (malignant hypertension, HCT related TMA, D+ HUS early years) deliver us a syndrome (TMA) likely to be highly responsive to plasma exchange and, in certain situations, to tailored corticotherapy, monoclonal CD20 Ab, C5 Ab.]]>
Thu, 25 Sep 2014 16:33:41 GMT /slideshow/ttp-shu/39539860 cospim@slideshare.net(cospim) Ttp shu cospim TTP-HUS Thrombotic microangiopathy is marker for TTP/HUS as well as for DIC/DIC-like (secondary thrombotic microangiopathy-TMA), this giving us a first overlapping area. ADAMTS 13 (ADAMTS 13 Ab/ADAMTS 13 relative or absolute deficiency) - a recent marker for TTP, regulatory complement factors flaws (CFH, MCP-CD46, IF and CD46 Ab, CFH Ab as well)-pathogenetic elements in D- HUS, increased PAI 1-recently proved for TTP, all of this are nowadays valid pathogenetic lego bricks in that wall we call secondary TMA, this giving us our second overlapping area. Plasma exchange, grade IA recommendation for true TTP, has been gaining a place in the last decade in the supportive basket for secondary TMA(e.g., sepsis ), this giving us a third overlapping area. At least three overlapping areas and the lack of certain particular cases (malignant hypertension, HCT related TMA, D+ HUS early years) deliver us a syndrome (TMA) likely to be highly responsive to plasma exchange and, in certain situations, to tailored corticotherapy, monoclonal CD20 Ab, C5 Ab. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/ttp-shu-140925163341-phpapp01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> TTP-HUS Thrombotic microangiopathy is marker for TTP/HUS as well as for DIC/DIC-like (secondary thrombotic microangiopathy-TMA), this giving us a first overlapping area. ADAMTS 13 (ADAMTS 13 Ab/ADAMTS 13 relative or absolute deficiency) - a recent marker for TTP, regulatory complement factors flaws (CFH, MCP-CD46, IF and CD46 Ab, CFH Ab as well)-pathogenetic elements in D- HUS, increased PAI 1-recently proved for TTP, all of this are nowadays valid pathogenetic lego bricks in that wall we call secondary TMA, this giving us our second overlapping area. Plasma exchange, grade IA recommendation for true TTP, has been gaining a place in the last decade in the supportive basket for secondary TMA(e.g., sepsis ), this giving us a third overlapping area. At least three overlapping areas and the lack of certain particular cases (malignant hypertension, HCT related TMA, D+ HUS early years) deliver us a syndrome (TMA) likely to be highly responsive to plasma exchange and, in certain situations, to tailored corticotherapy, monoclonal CD20 Ab, C5 Ab.
Ttp shu from Cosmin Balan
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Short bowel syndrome acid base physiology /slideshow/short-bowel-syndrome-acid-base-physiology/39539673 sdr-140925162809-phpapp02
acid base physiology will be covered quantitatively through Stewart's eyes]]>

acid base physiology will be covered quantitatively through Stewart's eyes]]>
Thu, 25 Sep 2014 16:28:09 GMT /slideshow/short-bowel-syndrome-acid-base-physiology/39539673 cospim@slideshare.net(cospim) Short bowel syndrome acid base physiology cospim acid base physiology will be covered quantitatively through Stewart's eyes <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/sdr-140925162809-phpapp02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> acid base physiology will be covered quantitatively through Stewart&#39;s eyes
Short bowel syndrome acid base physiology from Cosmin Balan
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Acid Base Physiology Stewart and beyond /slideshow/prezentare-eab-finala-39539535/39539535 prezentareeabfinala-140925162341-phpapp02
acid base equilibrium Stewart - centered Gilfix approach quantitative reasoning]]>

acid base equilibrium Stewart - centered Gilfix approach quantitative reasoning]]>
Thu, 25 Sep 2014 16:23:41 GMT /slideshow/prezentare-eab-finala-39539535/39539535 cospim@slideshare.net(cospim) Acid Base Physiology Stewart and beyond cospim acid base equilibrium Stewart - centered Gilfix approach quantitative reasoning <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/prezentareeabfinala-140925162341-phpapp02-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> acid base equilibrium Stewart - centered Gilfix approach quantitative reasoning
Acid Base Physiology Stewart and beyond from Cosmin Balan
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Contrast Induced Nephropathy /slideshow/cin-nic/39538884 cin-nic-140925160118-phpapp01
CIN - epiphenomenon or self existent?]]>

CIN - epiphenomenon or self existent?]]>
Thu, 25 Sep 2014 16:01:18 GMT /slideshow/cin-nic/39538884 cospim@slideshare.net(cospim) Contrast Induced Nephropathy cospim CIN - epiphenomenon or self existent? <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/cin-nic-140925160118-phpapp01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> CIN - epiphenomenon or self existent?
Contrast Induced Nephropathy from Cosmin Balan
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Abord arterial si venos /slideshow/abord-arterial-si-venos/39538705 abordarterialsivenos-140925155528-phpapp01
abord arterial si venos periferic + math reasoning]]>

abord arterial si venos periferic + math reasoning]]>
Thu, 25 Sep 2014 15:55:28 GMT /slideshow/abord-arterial-si-venos/39538705 cospim@slideshare.net(cospim) Abord arterial si venos cospim abord arterial si venos periferic + math reasoning <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/abordarterialsivenos-140925155528-phpapp01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> abord arterial si venos periferic + math reasoning
Abord arterial si venos from Cosmin Balan
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Monitoring hemodynamics-lost in translation /slideshow/monitoring-hemodynamicslost-in-translation/39494334 newmicrosoftpowerpointpresentationnew-140924164421-phpapp01
fractals and hemodynamics are brought together just for the fun of it!]]>

fractals and hemodynamics are brought together just for the fun of it!]]>
Wed, 24 Sep 2014 16:44:21 GMT /slideshow/monitoring-hemodynamicslost-in-translation/39494334 cospim@slideshare.net(cospim) Monitoring hemodynamics-lost in translation cospim fractals and hemodynamics are brought together just for the fun of it! <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/newmicrosoftpowerpointpresentationnew-140924164421-phpapp01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> fractals and hemodynamics are brought together just for the fun of it!
Monitoring hemodynamics-lost in translation from Cosmin Balan
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Guytonian approach to shock - mean systemic filling pressure centered /slideshow/guytonian-approach-to-shock-mean-systemic-filling-pressure-centered-39306854/39306854 guytonianapproachtoshock1-140919180247-phpapp01
In a world of binary decision there remains little room for applied maths and physiology. Or maybe not... Parkin's approach brings out a forgotten tool-the volume state. Although reductionistic as well as Guyton's entire view, it might be a better language for us, for clinicians and for all those lost in translation when they've stumbled across loose binary decisions such as SVV,PPV,SPV etc. Mean systemic filling pressure has been resurrected. Parkin, Maas, Pinsky and Geerts have come a long way from Versprille. ]]>

In a world of binary decision there remains little room for applied maths and physiology. Or maybe not... Parkin's approach brings out a forgotten tool-the volume state. Although reductionistic as well as Guyton's entire view, it might be a better language for us, for clinicians and for all those lost in translation when they've stumbled across loose binary decisions such as SVV,PPV,SPV etc. Mean systemic filling pressure has been resurrected. Parkin, Maas, Pinsky and Geerts have come a long way from Versprille. ]]>
Fri, 19 Sep 2014 18:02:47 GMT /slideshow/guytonian-approach-to-shock-mean-systemic-filling-pressure-centered-39306854/39306854 cospim@slideshare.net(cospim) Guytonian approach to shock - mean systemic filling pressure centered cospim In a world of binary decision there remains little room for applied maths and physiology. Or maybe not... Parkin's approach brings out a forgotten tool-the volume state. Although reductionistic as well as Guyton's entire view, it might be a better language for us, for clinicians and for all those lost in translation when they've stumbled across loose binary decisions such as SVV,PPV,SPV etc. Mean systemic filling pressure has been resurrected. Parkin, Maas, Pinsky and Geerts have come a long way from Versprille. <img style="border:1px solid #C3E6D8;float:right;" alt="" src="https://cdn.slidesharecdn.com/ss_thumbnails/guytonianapproachtoshock1-140919180247-phpapp01-thumbnail.jpg?width=120&amp;height=120&amp;fit=bounds" /><br> In a world of binary decision there remains little room for applied maths and physiology. Or maybe not... Parkin&#39;s approach brings out a forgotten tool-the volume state. Although reductionistic as well as Guyton&#39;s entire view, it might be a better language for us, for clinicians and for all those lost in translation when they&#39;ve stumbled across loose binary decisions such as SVV,PPV,SPV etc. Mean systemic filling pressure has been resurrected. Parkin, Maas, Pinsky and Geerts have come a long way from Versprille.
Guytonian approach to shock - mean systemic filling pressure centered from Cosmin Balan
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