Cold chain conference nov 7 2013 chicagoNick Pacitti
油
This document discusses vulnerabilities in cold chains that transport temperature-sensitive products like food. It begins by outlining various types of refrigerated facilities and vehicles used in cold chains. It then emphasizes the importance of establishing clear cold chain protocols, standards, and continuous temperature monitoring. Examples are provided showing how average temperatures over time impact product quality. The document suggests evaluating fleet operations and rationalizing asset sizes once cold chain standards are established. Overall it promotes a scientific, data-driven approach to cold chain management to improve food safety, quality control and supply chain efficiency.
An introduction to EECO2-Energy Efficiency Consultancy LimitedEECO2
油
EECO2 is an energy efficiency consultancy that offers services to reduce HVAC energy costs in the pharmaceutical and life sciences industries. They have over 100 combined years of experience in design, construction, and operation of technical facilities. Their approach involves identifying opportunities to reduce air changes and optimize HVAC systems through workshops with clients. Case studies show they have helped clients in multiple countries reduce energy costs by 10-45% while maintaining product quality standards.
EECO2 GMP critical HVAC energy cost reductionKeith Beattie
油
EECO2 is an energy efficiency consultancy that offers services to reduce HVAC energy costs in the pharmaceutical and life sciences industries. They have over 100 combined years of experience in design, construction, and operation of technical facilities. Their approach involves identifying opportunities to reduce air changes and optimize existing systems to lower energy use without compromising product quality. Case studies demonstrate they have helped clients achieve 15-30% savings through measures like reduced air flows, improved controls, and non-operational setbacks.
Validation & calibration in pharma (M shahzad (PAKISTAN) 03325637049)Muhammad Shahzad
油
This document discusses calibration and validation processes that are important for ensuring quality in the pharmaceutical industry. It defines calibration as establishing the relationship between measurement values from an instrument and known standard values. Regular calibration of important instruments like balances, thermometers, and testing equipment is emphasized. The document also describes qualification which verifies that equipment is properly installed and works correctly. Validation ensures manufacturing processes and cleaning procedures consistently produce the expected results.
Caltech Private Limited held a meeting to discuss calibration. They explained that calibration verifies the accuracy of instruments by comparing them to standard references. It is important to calibrate regularly to avoid false test results. The benefits of calibration include ensuring accuracy, minimizing breakdowns, and meeting certification requirements. Calibration is also important for quality improvement, safety, and interrelating quality and productivity. Caltech recommends on-site calibration for pharmaceuticals. They provide quality calibration services with accredited equipment and traceable standards.
A practical approach to pharmaceutical HVAC energy reductionEECO2
油
This document outlines strategies for reducing energy use in pharmaceutical HVAC systems. It identifies common areas with high energy savings potential, such as reducing air change rates and implementing night/weekend setbacks. Barriers to energy reduction like lack of funding and QA approval are discussed. The presentation recommends hosting team-based "energy kaizens" to identify opportunities and gain stakeholder buy-in. Case studies show projects at pharmaceutical plants that cut HVAC energy use up to 66% by optimizing air flow and implementing variable speed controls.
Pharmaceutical HVAC (Heating, ventilating, and air conditioning; also heating...Palash Das
油
This slide is represent the HVAC design,qualification and operational approach. As we know HVAC is important system for maintaining clean room. This presentation is made based on the requirement of Pharmaceutical Industry. All parameter are considered based on the current guidelines aspect.
In the fall of 2016, the EPA updated Section 608 of the Clean Air Act (CAA) by extending ozone depleting refrigerants to include substitutes like hydrofluorocarbons (HFCs). These changes strengthen the existing program, effectively reducing climate-damaging emissions from air conditioning and refrigeration equipment.
Thomas Lally has over 20 years of experience as a power plant operator and boiler plant operator. He holds numerous licenses including a Maryland First Grade Stationary Engineers License. He has a Bachelor's Degree in Environmental Engineering Technology from Temple University. Currently he works as a Power Plant Operator for NAES Corporation, where his responsibilities include operating and maintaining steam production processes, software systems, and ensuring environmental compliance.
Testo The Strong Partner for Facility油Managers.Lothar Zorn
油
Your advantages with Testo
Operating costs, user convenience, energy consumption: as a facility manager, you need to keep an eye on a number of things. So it is good to have a strong partner who supplies integrated solutions for your building management requirements.
You can find these solutions at Testo. Because the hightech company from the Black Forest has stood for precision measuring technology with innovative operability for 60 years. Measuring instruments from Testo are in use everywhere where it is important to save time and resources and to protect the environment and human health.
Whether it involves heating, HVAC, air conditioning, ventilation and refrigeration systems or electrical installations: you get measuring solutions for all building systems from a single source at Testo. Testos measuring instruments enable faster testing, more convenient maintenance and more efficient setting of systems. In addition, you ensure the thermal comfort level in indoor areas and early detection of mould, humidity, damage to buildings and energy losses thanks to thermography.
The range Testo offers is completed by a wide variety of services which make your work easier. From individual advice, along with repair and spare part services, via seminars and training, through to professional test equipment management Testo is your strong partner for measuring solutions and services in facility management
Quality assurance maintenance of hvac system in pharmaceutical industryShahbazNadaf
油
The document discusses quality assurance maintenance of HVAC systems. It describes the importance of regularly maintaining HVAC systems to ensure consistent performance and longevity. Key aspects of HVAC maintenance include inspecting and changing air filters, cleaning debris, checking refrigerant levels, and lubricating moving parts. The document provides tips for maintenance schedules and lists 30 points to check during maintenance.
Staying Ahead of the Audit Curve with Food Industry Process AuditsAlchemy Systems
油
Process audits are a new approach to evaluating the effectiveness of your SQF System. They involve selecting a finished product lot and then auditing all the specific SQF components related to that lot. With SQFI considering adopting this methodology in SQF Code Edition 8, now is the time to learn about this process and start conducting your own internal process audits. Join this session to learn more about this process to test your system now and be ready for whats coming soon!
The document outlines the agenda for a temperature control seminar hosted by Expeditors. The morning session will include introductions, an overview of Expeditors and their temperature control services, a discussion of common temperature ranges and trends in temperature control strategies, and case studies of US exports and imports requiring temperature control. The afternoon will include a facility tour, discussions of compliance and risk management, and developments in Expeditors' temperature control offerings.
This document discusses commissioning, qualification, and maintenance of HVAC systems. It covers:
- Commissioning includes setting up, balancing, adjusting and testing the HVAC system to ensure it meets requirements, and training personnel. Records of installation, design measurements, manuals and reports are maintained.
- Qualification validates the HVAC system meets design specifications. It includes design qualification, installation qualification, operational qualification, and performance qualification based on a risk analysis. Critical parameters and components are tested.
- Maintenance includes inspection of documentation, operating and maintenance procedures, environmental records, and discussion of out of specification actions. Filters are changed and devices calibrated by trained personnel to ensure product quality and continued qualification.
This document contains a bio data and resume for Odogbor Samuel Madison. It summarizes his objective to work assiduously with a progressive team, his experience as a Compressor Operations and Maintenance Support Engineer from 2011 to present at Hally Brown Efeluc consortium, and his education which includes an HND in Mechanical Engineering from Federal Polytechnic Idah.
Calibration of the measuring instrument is the process in which the readings obtained from the instrument are compared with the sub-standards in the laboratory at several points along the scale of the instrument. As per the results obtained from the readings obtained of the instrument and the sub-standards, the curve is plotted. If the instrument is accurate there will be matching of the scales of the instrument and the sub-standard. If there is deviation of the measured value from the instrument against the standard value, the instrument is calibrated to give the correct values.
All the new instruments have to be calibrated against some standard in the very beginning. For the new instrument the scale is marked as per the sub-standards available in the laboratories, which are meant especially for this purpose. After continuous use of the instrument for long periods of time, sometimes it loses its calibration or the scale gets distorted, in such cases the instrument can be calibrated again if it is in good reusable condition.
Even if the instruments in the factory are working in the good condition, it is always advisable to calibrate them from time-to-time to avoid wrong readings of highly critical parameters. This is very important especially in the companies where very high precision jobs are manufactured with high accuracy.
All the measuring instruments for measurement of length, pressure, temperature etc should be calibrated against some standard scale at the regular intervals as specified by the manufacturer. There are different methods or techniques of calibration, which are applied depending on whether it is routine calibration or if it is for special purpose where highly accurate calibration of the instruments is desired. In many cases different methods of calibration are applied for all the individual instruments. No what type of calibrations is being done, all of them are done in the laboratory.
The calibration of the instrument is done in the laboratory against the sub-standard instruments, which are used very rarely for this sole purpose. These sub-standards are kept in highly controlled air-conditioned atmosphere so that there their scale does not change with the external atmospheric changes.
To maintain the accuracy of the sub-standards, they are checked periodically against some standard which is kept in the metrological laboratories under highly secured, safe, clean and air conditioned atmosphere. Finally, standards can be checked against the absolute measurements of the quantity, which the instruments are designed to measure.
This document provides an overview and agenda for a hydronic heating conference. It discusses the benefits of condensing boilers over conventional boilers, including increased efficiency from condensing combustion gases. It also notes research being conducted on optimizing condensing boiler installations in Minnesota homes to improve efficiency and contractor confidence. The research involves monitoring existing condensing boiler installations, retrocommissioning them to lower supply temperatures and better match load, and installing new boilers using developed quality installation protocols.
Thermal Validation Equipment rental for Autoclave Validation, Freeze Drier Validation, Temperature and Humidity mapping. Including Kaye Validator 2000, Ellab Tracksense Pro and Vaisala Dataloggers.
Supply chain management involves planning and managing the flow of goods and services. It includes sourcing, procurement, conversion, and logistics management processes. SCM plays an important role in obtaining materials and services on budget and on time for end users. The key SCM processes are procurement, inventory management, and logistics. Effective SCM requires managing purchase requisitions, vendor selection, inventory levels, material receiving, inspection, storage and issue processes.
1) This document provides a 10 step guide for completing a Hazard Analysis and Critical Control Points (HACCP) plan, including defining the scope of operations, creating a process flow diagram, identifying hazards and control measures, determining critical control points, establishing monitoring procedures, and documenting the HACCP plan and records.
2) Key steps include identifying food safety hazards at each process step, determining critical limits for control measures at critical control points, establishing monitoring and corrective action procedures, and reviewing and updating the HACCP plan annually or when changes occur.
3) A Food Safety Management Diary is recommended for record keeping, with daily, four-weekly, and annual review checks documented to provide evidence that food
This presentation looks at superheat in porous load autoclaves. It explains what superheat is, why superheat is a problem and identifies the causes superheat.
If you are seeing wet loads in your autoclave we can help, this presentation helps show what a wet load is and why its important. It also includes some of the potential root causes of wet loads.
IRJET- Performance Assessment of Hydrocarbon Refrigerant in Air ConditionerIRJET Journal
油
This document discusses an experimental analysis of hydrocarbon refrigerants in air conditioners as an alternative to traditional refrigerants. The researchers tested various mixtures of propane (R290) and isobutane (R600a) in an air conditioning system and analyzed the coefficient of performance (COP), cooling capacity, and energy consumption compared to R134a. They found that the hydrocarbon blend had a higher COP and cooling capacity but lower energy consumption than R134a. In conclusion, the hydrocarbon blend R290/R600a showed promising performance as a potential replacement for R134a in air conditioners and could help reduce environmental impacts.
This document discusses measurement uncertainty and the work of the National Measurement Institute (NMI) in Australia to reduce uncertainty. The NMI defines key terms related to measurement uncertainty according to international standards. It works to develop chemical reference materials and methods, conduct proficiency testing programs, validate quantitative analysis techniques, and participate in international collaborations. The goal is to improve the accuracy, traceability and comparability of chemical measurements for applications like food safety testing and doping analysis in sports.
Cold Storage Warehouse Best Practices: Forecasting & End-to-End Temperature M...Angela Carver
油
As products evolve and consumer demands change cold storage warehouse space is a more critical branch of the supply chain than ever. Products being stored in these refrigerated warehouses include frozen and refrigerated food, pharmaceuticals, petro-chemicals and high-tech electronics. Many of these products are strictly regulated by government agencies such as the FDA. To maintain compliant with these regulations many cold storage operations are focusing on implementing industry best practices. A top priority has continued to be temperature forecasting and monitoring and technology upgrades.
Forecasting temperature demand helps businesses operating in the cold chain to accommodate to changes in product demand and the financial implications. Completing inventory forecasts often will help to give your business a clear understanding of storage space requirements and what changes can be made the make the most of your existing facility space.
One way cold storage warehouses are making the most of their space is by implementing temporary curtains that allow them to break up facility space in order to create, expand or reduce the square footage of temperature zones. The flexibility of this tool helps refrigerated warehouse operators to reduce energy consumption while also ensuring temperature consistency to avoid spoiling.
In an effort to avoid the average 6 recalls that occur in the U.S. each day cold storage warehouses are implementing new and cutting edge technologies to aid in the tracking and monitoring of inventory temperature and condition. These tools include: thermometers for manual QA readings on an inventory or temperature zone level, RFID tags for passive temperature monitoring and location identification, data loggers for in-transit deliveries direct-to-customer, smart shipping containers for LTL and FTL shipments, and WMS for a centralized data collection and storage database. All of these tools used in varying combinations can help cold storage warehouses to reduce costs, improve data accuracy, guarantee product quality and maintain regulatory compliance.
Evaluate how these technologies can help your refrigerated warehouse implement industry best practices in temperature monitoring and tracking and solve any pre-existing QA issues today. Contact Datex experts with questions or for more information on this topic at marketing@datexcorp.com or 800.933.2839 ext 243.
Maintaining end-to-end cold chain integrity is a critical focus for all cold storage operations as much of their inventory is consumed directly by end customers. If any instance of impropriety throughout the supply chain occurs it could lead to widespread sickness or death. On average, 10% of all pharmaceutical inventory is temperature controlled and a significantly larger portion of food products are also temperature controlled. Any contamination could result in thousands or even millions of dollars in inventory loss, logistics costs and settlement fees. Preventing inventory contamination in the cold chain has increased in complexity as the supply chain has globalized. A larger portion of temperature regulated goods are crossing international borders creating both regulatory challenges as well more opportunities for failure and/or complication before goods reach their final destination. Some of the most notable regulations impacting the cold chain are the Sanitary Food Transportation Act, Food Safety Modernization Act (FSMA) and EU Good Distribution Practices. These pieces of legislation impact all key supply chain players including those that manufacture, store, transport and sell refrigerated and frozen products. Much of this legislation closely regulates the tracking and storage of handling and temperature related inventory data.
In an effort to solve cold chain challenges related to temperature maintenance, monitoring and recording supply chain operators handling temperature regulated inventory have begun to implement some successful industry best practices. Inventory pre-cooling has proven successful in reducing the wear and tear on refrigeration equipment and helps to guarantee temperature consistency from the time it is loaded until it is unloaded. Many cold chain businesses have also installed trailer condition monitoring systems that monitor temperature conditions in real time and send alerts if any unacceptable temperature variations are encountered. Packaging optimization has also proven useful in extending shelf life and improving product condition. In addition to monitoring trailer conditions, cold chain operators are also implementing inventory temperature monitoring technologies to track inventory status on a piece by piece or pallet by pallet basis. Retailers have also been encouraged to develop standard operating procedures (SOPs) for receiving to ensure only inventory of the highest quality ends up on their shelves and in consumer hands. With capacity increasing and the supply chain growing globally it is more critical than ever that the cold chain implement these best practices in order to keep consumers safe.
In the fall of 2016, the EPA updated Section 608 of the Clean Air Act (CAA) by extending ozone depleting refrigerants to include substitutes like hydrofluorocarbons (HFCs). These changes strengthen the existing program, effectively reducing climate-damaging emissions from air conditioning and refrigeration equipment.
Thomas Lally has over 20 years of experience as a power plant operator and boiler plant operator. He holds numerous licenses including a Maryland First Grade Stationary Engineers License. He has a Bachelor's Degree in Environmental Engineering Technology from Temple University. Currently he works as a Power Plant Operator for NAES Corporation, where his responsibilities include operating and maintaining steam production processes, software systems, and ensuring environmental compliance.
Testo The Strong Partner for Facility油Managers.Lothar Zorn
油
Your advantages with Testo
Operating costs, user convenience, energy consumption: as a facility manager, you need to keep an eye on a number of things. So it is good to have a strong partner who supplies integrated solutions for your building management requirements.
You can find these solutions at Testo. Because the hightech company from the Black Forest has stood for precision measuring technology with innovative operability for 60 years. Measuring instruments from Testo are in use everywhere where it is important to save time and resources and to protect the environment and human health.
Whether it involves heating, HVAC, air conditioning, ventilation and refrigeration systems or electrical installations: you get measuring solutions for all building systems from a single source at Testo. Testos measuring instruments enable faster testing, more convenient maintenance and more efficient setting of systems. In addition, you ensure the thermal comfort level in indoor areas and early detection of mould, humidity, damage to buildings and energy losses thanks to thermography.
The range Testo offers is completed by a wide variety of services which make your work easier. From individual advice, along with repair and spare part services, via seminars and training, through to professional test equipment management Testo is your strong partner for measuring solutions and services in facility management
Quality assurance maintenance of hvac system in pharmaceutical industryShahbazNadaf
油
The document discusses quality assurance maintenance of HVAC systems. It describes the importance of regularly maintaining HVAC systems to ensure consistent performance and longevity. Key aspects of HVAC maintenance include inspecting and changing air filters, cleaning debris, checking refrigerant levels, and lubricating moving parts. The document provides tips for maintenance schedules and lists 30 points to check during maintenance.
Staying Ahead of the Audit Curve with Food Industry Process AuditsAlchemy Systems
油
Process audits are a new approach to evaluating the effectiveness of your SQF System. They involve selecting a finished product lot and then auditing all the specific SQF components related to that lot. With SQFI considering adopting this methodology in SQF Code Edition 8, now is the time to learn about this process and start conducting your own internal process audits. Join this session to learn more about this process to test your system now and be ready for whats coming soon!
The document outlines the agenda for a temperature control seminar hosted by Expeditors. The morning session will include introductions, an overview of Expeditors and their temperature control services, a discussion of common temperature ranges and trends in temperature control strategies, and case studies of US exports and imports requiring temperature control. The afternoon will include a facility tour, discussions of compliance and risk management, and developments in Expeditors' temperature control offerings.
This document discusses commissioning, qualification, and maintenance of HVAC systems. It covers:
- Commissioning includes setting up, balancing, adjusting and testing the HVAC system to ensure it meets requirements, and training personnel. Records of installation, design measurements, manuals and reports are maintained.
- Qualification validates the HVAC system meets design specifications. It includes design qualification, installation qualification, operational qualification, and performance qualification based on a risk analysis. Critical parameters and components are tested.
- Maintenance includes inspection of documentation, operating and maintenance procedures, environmental records, and discussion of out of specification actions. Filters are changed and devices calibrated by trained personnel to ensure product quality and continued qualification.
This document contains a bio data and resume for Odogbor Samuel Madison. It summarizes his objective to work assiduously with a progressive team, his experience as a Compressor Operations and Maintenance Support Engineer from 2011 to present at Hally Brown Efeluc consortium, and his education which includes an HND in Mechanical Engineering from Federal Polytechnic Idah.
Calibration of the measuring instrument is the process in which the readings obtained from the instrument are compared with the sub-standards in the laboratory at several points along the scale of the instrument. As per the results obtained from the readings obtained of the instrument and the sub-standards, the curve is plotted. If the instrument is accurate there will be matching of the scales of the instrument and the sub-standard. If there is deviation of the measured value from the instrument against the standard value, the instrument is calibrated to give the correct values.
All the new instruments have to be calibrated against some standard in the very beginning. For the new instrument the scale is marked as per the sub-standards available in the laboratories, which are meant especially for this purpose. After continuous use of the instrument for long periods of time, sometimes it loses its calibration or the scale gets distorted, in such cases the instrument can be calibrated again if it is in good reusable condition.
Even if the instruments in the factory are working in the good condition, it is always advisable to calibrate them from time-to-time to avoid wrong readings of highly critical parameters. This is very important especially in the companies where very high precision jobs are manufactured with high accuracy.
All the measuring instruments for measurement of length, pressure, temperature etc should be calibrated against some standard scale at the regular intervals as specified by the manufacturer. There are different methods or techniques of calibration, which are applied depending on whether it is routine calibration or if it is for special purpose where highly accurate calibration of the instruments is desired. In many cases different methods of calibration are applied for all the individual instruments. No what type of calibrations is being done, all of them are done in the laboratory.
The calibration of the instrument is done in the laboratory against the sub-standard instruments, which are used very rarely for this sole purpose. These sub-standards are kept in highly controlled air-conditioned atmosphere so that there their scale does not change with the external atmospheric changes.
To maintain the accuracy of the sub-standards, they are checked periodically against some standard which is kept in the metrological laboratories under highly secured, safe, clean and air conditioned atmosphere. Finally, standards can be checked against the absolute measurements of the quantity, which the instruments are designed to measure.
This document provides an overview and agenda for a hydronic heating conference. It discusses the benefits of condensing boilers over conventional boilers, including increased efficiency from condensing combustion gases. It also notes research being conducted on optimizing condensing boiler installations in Minnesota homes to improve efficiency and contractor confidence. The research involves monitoring existing condensing boiler installations, retrocommissioning them to lower supply temperatures and better match load, and installing new boilers using developed quality installation protocols.
Thermal Validation Equipment rental for Autoclave Validation, Freeze Drier Validation, Temperature and Humidity mapping. Including Kaye Validator 2000, Ellab Tracksense Pro and Vaisala Dataloggers.
Supply chain management involves planning and managing the flow of goods and services. It includes sourcing, procurement, conversion, and logistics management processes. SCM plays an important role in obtaining materials and services on budget and on time for end users. The key SCM processes are procurement, inventory management, and logistics. Effective SCM requires managing purchase requisitions, vendor selection, inventory levels, material receiving, inspection, storage and issue processes.
1) This document provides a 10 step guide for completing a Hazard Analysis and Critical Control Points (HACCP) plan, including defining the scope of operations, creating a process flow diagram, identifying hazards and control measures, determining critical control points, establishing monitoring procedures, and documenting the HACCP plan and records.
2) Key steps include identifying food safety hazards at each process step, determining critical limits for control measures at critical control points, establishing monitoring and corrective action procedures, and reviewing and updating the HACCP plan annually or when changes occur.
3) A Food Safety Management Diary is recommended for record keeping, with daily, four-weekly, and annual review checks documented to provide evidence that food
This presentation looks at superheat in porous load autoclaves. It explains what superheat is, why superheat is a problem and identifies the causes superheat.
If you are seeing wet loads in your autoclave we can help, this presentation helps show what a wet load is and why its important. It also includes some of the potential root causes of wet loads.
IRJET- Performance Assessment of Hydrocarbon Refrigerant in Air ConditionerIRJET Journal
油
This document discusses an experimental analysis of hydrocarbon refrigerants in air conditioners as an alternative to traditional refrigerants. The researchers tested various mixtures of propane (R290) and isobutane (R600a) in an air conditioning system and analyzed the coefficient of performance (COP), cooling capacity, and energy consumption compared to R134a. They found that the hydrocarbon blend had a higher COP and cooling capacity but lower energy consumption than R134a. In conclusion, the hydrocarbon blend R290/R600a showed promising performance as a potential replacement for R134a in air conditioners and could help reduce environmental impacts.
This document discusses measurement uncertainty and the work of the National Measurement Institute (NMI) in Australia to reduce uncertainty. The NMI defines key terms related to measurement uncertainty according to international standards. It works to develop chemical reference materials and methods, conduct proficiency testing programs, validate quantitative analysis techniques, and participate in international collaborations. The goal is to improve the accuracy, traceability and comparability of chemical measurements for applications like food safety testing and doping analysis in sports.
Cold Storage Warehouse Best Practices: Forecasting & End-to-End Temperature M...Angela Carver
油
As products evolve and consumer demands change cold storage warehouse space is a more critical branch of the supply chain than ever. Products being stored in these refrigerated warehouses include frozen and refrigerated food, pharmaceuticals, petro-chemicals and high-tech electronics. Many of these products are strictly regulated by government agencies such as the FDA. To maintain compliant with these regulations many cold storage operations are focusing on implementing industry best practices. A top priority has continued to be temperature forecasting and monitoring and technology upgrades.
Forecasting temperature demand helps businesses operating in the cold chain to accommodate to changes in product demand and the financial implications. Completing inventory forecasts often will help to give your business a clear understanding of storage space requirements and what changes can be made the make the most of your existing facility space.
One way cold storage warehouses are making the most of their space is by implementing temporary curtains that allow them to break up facility space in order to create, expand or reduce the square footage of temperature zones. The flexibility of this tool helps refrigerated warehouse operators to reduce energy consumption while also ensuring temperature consistency to avoid spoiling.
In an effort to avoid the average 6 recalls that occur in the U.S. each day cold storage warehouses are implementing new and cutting edge technologies to aid in the tracking and monitoring of inventory temperature and condition. These tools include: thermometers for manual QA readings on an inventory or temperature zone level, RFID tags for passive temperature monitoring and location identification, data loggers for in-transit deliveries direct-to-customer, smart shipping containers for LTL and FTL shipments, and WMS for a centralized data collection and storage database. All of these tools used in varying combinations can help cold storage warehouses to reduce costs, improve data accuracy, guarantee product quality and maintain regulatory compliance.
Evaluate how these technologies can help your refrigerated warehouse implement industry best practices in temperature monitoring and tracking and solve any pre-existing QA issues today. Contact Datex experts with questions or for more information on this topic at marketing@datexcorp.com or 800.933.2839 ext 243.
Maintaining end-to-end cold chain integrity is a critical focus for all cold storage operations as much of their inventory is consumed directly by end customers. If any instance of impropriety throughout the supply chain occurs it could lead to widespread sickness or death. On average, 10% of all pharmaceutical inventory is temperature controlled and a significantly larger portion of food products are also temperature controlled. Any contamination could result in thousands or even millions of dollars in inventory loss, logistics costs and settlement fees. Preventing inventory contamination in the cold chain has increased in complexity as the supply chain has globalized. A larger portion of temperature regulated goods are crossing international borders creating both regulatory challenges as well more opportunities for failure and/or complication before goods reach their final destination. Some of the most notable regulations impacting the cold chain are the Sanitary Food Transportation Act, Food Safety Modernization Act (FSMA) and EU Good Distribution Practices. These pieces of legislation impact all key supply chain players including those that manufacture, store, transport and sell refrigerated and frozen products. Much of this legislation closely regulates the tracking and storage of handling and temperature related inventory data.
In an effort to solve cold chain challenges related to temperature maintenance, monitoring and recording supply chain operators handling temperature regulated inventory have begun to implement some successful industry best practices. Inventory pre-cooling has proven successful in reducing the wear and tear on refrigeration equipment and helps to guarantee temperature consistency from the time it is loaded until it is unloaded. Many cold chain businesses have also installed trailer condition monitoring systems that monitor temperature conditions in real time and send alerts if any unacceptable temperature variations are encountered. Packaging optimization has also proven useful in extending shelf life and improving product condition. In addition to monitoring trailer conditions, cold chain operators are also implementing inventory temperature monitoring technologies to track inventory status on a piece by piece or pallet by pallet basis. Retailers have also been encouraged to develop standard operating procedures (SOPs) for receiving to ensure only inventory of the highest quality ends up on their shelves and in consumer hands. With capacity increasing and the supply chain growing globally it is more critical than ever that the cold chain implement these best practices in order to keep consumers safe.
This document discusses the importance of maintaining proper cold chain management for pharmaceutical products, especially clinical trial materials. It covers definitions of active and passive cold chain systems, requirements for validation of cold chain processes, challenges in global clinical trials, and the roles of service providers and regulations. Proper cold chain is crucial for ensuring product quality and safety.
Session 02 - Introduction to Industrial AutomationVidyaIA
油
This document provides an overview of industrial automation and control systems. It begins with an introduction to different types of industries and their classification as either discrete or process manufacturing. It then discusses industrial automation, describing it as the use of technologies and automatic control devices to operate industrial processes without significant human intervention. The document outlines the advantages of automation, such as improved productivity, quality, safety and information accuracy. It also describes the different levels or layers of an automation system, including the field, control, supervisory and enterprise levels. Finally, it provides an agenda for future training sessions on topics related to industrial automation.
This document provides an overview of industrial automation and control systems. It begins with an agenda that covers industries and classifications, introduction to industrial automation, and examples of process and discrete manufacturing. It then defines process and discrete industries, and provides examples of a car assembly line and oil refinery. The document introduces industrial automation as using technology and automatic controls to operate industrial processes without human intervention. It covers the advantages of automation including higher productivity, quality and safety. Finally, it describes the layers of an automation system including the field, control, supervisory and production, and information levels.
Reverse Technologies is a company based in San Jose, CA that was established to promote energy conservation. One of their energy conservation efforts is a patented Polarized Refrigerant Oil Additive called Compress Shield, which has been found to be highly effective by the U.S. Department of Energy. Compress Shield helps reduce operating costs by an average of 5% guaranteed, reduces maintenance costs, and extends equipment life by improving heat exchange and reducing friction in HVAC systems. Reverse Technologies performs inspections, establishes energy usage baselines, installs Compress Shield, and documents the energy savings achieved. The cost of applying Compress Shield typically pays for itself within 18 to 24 months through reduced energy costs.
How to Validate Temperatures Within the Supply ChainMichel Comtois
油
This document discusses how to validate temperatures within the supply chain for pharmaceuticals. It covers standards and regulations, the validation process including developing a protocol, packaging design and testing. Specific topics covered include trailer validation variables, Health Canada Guide 0069 requirements, ISTA testing standards, and how to design packaging and conduct validation testing. The goal is to document that temperatures are controlled throughout the logistics process.
In this session you will learn:
Self Introduction.
What does control system, industrial automation mean?
What is your expectation from this course?
For more information, visit: https://www.mindsmapped.com/courses/industrial-automation/complete-training-on-industrial-automation-for-beginners/
This document discusses quality assurance and quality control procedures for microlaboratories. It defines quality and quality management, and explains how quality is ensured in laboratories through controlling all factors that influence reliable test results. Quality assurance aims to ensure accurate and reliable data generation and use. Key quality control procedures discussed include regular equipment maintenance and calibration, sterilization validation methods, reagent and media quality control, and environmental monitoring. Adhering to these standardized quality control protocols is important for generating credible results and safeguarding patient health.
Global regulatory agencies are pushing for comprehensive cold chain monitoring programs that extend from raw materials to distribution to patients. Proper validation and qualification of storage facilities has become necessary to demonstrate compliance with good manufacturing practices. Sensitech provides a variety of validation services including installation, operational, and performance qualification to ensure storage environments consistently meet acceptance criteria and protect product quality throughout the supply chain.
This document discusses Secop's journey towards more sustainable refrigeration technologies. It outlines their transition from HFC refrigerants like R404A to natural refrigerants like propane (R290) and the optimization of systems through variable speed compressor technology. The document describes case studies of converting a commercial freezer from R404A to R290 and further improving it with a variable speed compressor. It also discusses Secop's optimized simulation-based approach to development that reduces testing time and costs compared to traditional methods. Finally, it provides a brief overview of Secop's portfolio and experience in refrigeration.
The document discusses validation of a hot air oven. It defines equipment validation and introduces the types and principles of dry heat sterilizers. The validation process for a hot air oven includes design qualification, installation qualification, operational qualification, and performance qualification. Key tests involve heat penetration studies, heat distribution studies, and biochallenge/pyrochallenge studies to develop a sterilization cycle. Routine monitoring after validation ensures the oven remains in a state of control. All validation documentation must be thorough and stored for regulatory review.
Awareness Session On BRC - Global Standards for Food Saftey Farid Ud Din
油
The document provides information on the Global Standard for Food Safety (BRC) including its history, key characteristics, certification scope, grading system, and the contents of Section II which outlines the requirements. Some key points:
- BRC was originally developed in 1998 and is now called the Global Standard for Food Safety, based on HACCP.
- It focuses on quality, hygiene, safety and has a grading system (A+ to D) that determines surveillance audit frequency.
- Section II covers requirements like senior management commitment, the food safety plan (including HACCP, PRPs), food safety & quality management systems, site standards and more.
- There are fundamental clauses that are critical
2. Creating clear protocols and product standards
Evaluating cold chains for trends and weaknesses
Managing product/information flows at transfer points
Minimizing cost while maximizing quality
Vulnerabilities in the Cold Chain
3. Description US Units
Public Blast Freezers 51,000
Private Blast Freezers 100,000
Public Refrigerated/Freezer Facilities 12,800
Private Refrigerated/Freezer Facilities 114,000
Public Coolers 1,600,000
Private Coolers 2,200,000
Restaurant Coolers/Freezers greater than 1K sf 4,000,000+
Public Refrigerated Trailers 30,000,000
Private Refrigerated Trailers 9,000,000
Public Refrigerated Railcars 31,000
Private Refrigerated Railcars 35,000
Sources:
International Association of Refrigerated Warehouses
World Logistics Organization
International Refrigerated Transportation Association
International Association of Cold Storage Construction
Refrigerated distribution is huge
8. Another Example of Poor Cold
Chain Performance
Adulterated
Product
Compromised
Product
Desired
Product
45 to 50
+
40 to 44.9
< 39.9
42%
12%
46%
88% of product delivered
had been compromised and
based on science should
have been disposed of
Cumulative Average
Temperatures
10. Protocols and Product Standards
An example of an actual Desired State for large shipper
An optimal carrier base for chilled loads that properly balances
service and cost
Clearly defined carrier expectations for temperature control and
rigorous carrier performance management
Well defined processes, standard work and data sources for chilled
product staging, loading and shipping; clear accountability at each
step of the process
Systemic data gathering around temperature abused loads across
all chilled product categories
Selection and application of temperature monitoring technology
that expands data capture across chilled shipments
11. Required Component Description
Available cold chain policy
Provides guidance and temperature thresholds on all the elements from
pre-loading to loading , yard mgmt/trailer staging, monitoring through to
delivery
Determine product limits
Using real life operating environment simulate the effect of
cumulative average temperatures on product stability and spoilage
rates
Temperature range stipulations
Based on spoilage rates develop trailer temperature protocol in
monitoring temps and given thresholds
Defined temperature trigger points
Based on defined thresholds develop stages of intervention and
required decision points
End to end t monitoring - Rules based
control and monitoring systems
Apply temperature and quality protocol in monitoring trailer temps
during pre-chill, loading, staging, and delivery cycles
Suitable staff training
Revise cold chain (HACCP and Quality Management System based) training
for associates
Self and third-party audits
Periodic monitoring of the system in assessing how the system is
performing as planned and required
A formalized validation process
assuring the process works
Actual monitoring, validation and quantification of how well the system
works and what adjustments are needed in bringing system in line with
established standards
Protocols and Product Standards
12. Initiative Now Next Later Impact
Fix what is wrong
Develop Cold Chain policy and product
standards how does product behave in
real life operating conditions for all
seasons
Develop temperature performance index
Design and implement rules based
temperature monitoring
Selected training at management and
hourly levels
Review fleet utility and rationalize size
with a process in place and asset
productivity improved other
Develop audit to validate index
Protocols and Product Standards
13. Temperature as a Quality Control Point
Single point readings are irrelevant
Average temperature readings are irrelevant
Cumulative temperatures matter most
>50 A A A A A A
50 C A A A A A
48 G C C A A A
46 G C C C A A
44 G G C C C C
42 G G G G G C
39 - 41 G G G G G G
36 - 38 G G G G G G
Hours 2 4 6 8 10 12
Illustration Only
G = Good optimal quality
C = Compromised quality issue
A = Adulterated food safety risk
Protocols and Product Standards
14. Canary in the Mine
Cant focus on everything
Understand sensitivities of selected
products or product families
Use one or two product families for
guidance in determining thresholds
or cold chain specs
17. There is often resistance to cold chain issues
Once issues are identifiedwhat to do?
What is the cost-benefit in fixing
Cold Chain Evaluation
18. Rising consumer complaints
Need to set standards against product quality thresholds
Need to monitor the standard
Need for predictive capabilities in eliminating problems
before they arise
Capability to measure and control the cold chain
Cold Chain Evaluation
19. How to evaluate cold chains in
assessing trends and weaknesses
Need to look at Cold Chains in Totality
20. How to evaluate cold chains in
assessing trends and weaknesses
Understanding the entire cold chain doesnt stop at delivery
21. How to evaluate cold chains in
assessing trends and weaknesses
Even with the best monitoring things can wrong without being noticed
22. If you could, would you have a manager ride along the cold
chain, with a cell phone, reporting back critical operational data?
Who would be that manager?
Trailer Temperature
Temperature Profile
Product Quality Behavior
Reefer Mode
Reefer Set Point
Supply Air
Return Air
Product Temperature
Door Open or Close
Reefer Alarms
Location
23. Poor cold chain management has a direct
influence on cost and product quality
Refrigerated trucks ready for loading
24. Refrigerated dock design
to minimize energy and
temperature loss
This is an excellent option in minimizing
energy while maintaining product temps
25. Raising storage temperatures to save
energy: Is it worth it in the long-run?
Raising the holding temperature and reducing the heat gain through the walls
due to a reduced temperature differential inside to outside.
With 4 of insulation, raising the temperature will decrease the conduction into the
facility by 2%. The impact or change in effect of infiltration would be minimal with
a 5 deg. change so was not considered at this time.
Thus providing a 2% energy savings on a peak differential day
Raising the holding temperature, thereby allowing a reduction in compressor
suction temperature
if the compressor suction can be raised a corresponding 5 deg. then depending
on the system, there will be a reduction of 8-9% of required compressor brake-
horsepower
Kraft Foods engineers claim a 2% savings for every 1 psi increase. At these
temps we are about 4.5 psi increase, so this is a second validation of the 8-9%
savings.
Installing Variable Speed Drives
If the roofing is black, change to a reflective coating
This will reduce the heat gain through the roof
Can reduce the temperature of the air being drawn across the condenser coils
26. The focus on cold chain management improves the scientific basis for safety and control
processes. Monitoring of temperature in a proprietary way is done by using indicators that
can be measured easily, such as cumulative average ambient temperatures. This focus on
measurable indicators provides a more cost-effective approach to control than product
sampling and testing, which is more expensive and may not provide timely results. This is
especially important for foodborne microbial pathogens, because their incidence is low and
costs of testing are high.
To meet the goals of processors, retailers and the consumer, temperature standards must be
set to accommodate accurate product behavior over extended periods. Once established,
these standards can be measured in innovative ways that convert data into meaningful and
actionable information in better controlling processes. Setting product temperature
standards and measuring in innovative ways allow greater efficiency in meeting processors,
retailers and public health goals.
Cold Chain management is evolving into a regulatory tool, but more importantly, into a
supplier and retailer specific requirement. The reason is that it overcomes and solves for
the high information costs of setting and enforcing standards for microbial foodborne
pathogens. These information costs contribute to the market failure in food safety provision
and make design of effective interventions difficult. Moreover, a cold chain standard has
been proven to actually reduce food safety risks. It is an effective and useful performance
standard.
Epilogue