Farmacovigilancia - Pharmacological Surveillance

Mar 18, 2016Download as PPTX, PDF3 likes264 views

Clinical trials for several drugs including Tamiflu, Tamsulosin, Dabigatran, Agomelatine, and Liraglutide were found to have high percentages of unpublished results on ClinicalTrials.gov. A study found Tamiflu trials were 51% unpublished, Tamsulosin over 75% unpublished, and Dabigatran over 80% unpublished, raising concerns about incomplete dissemination of clinical trial data.

Farmacovigilancia - Pharmacological Surveillance

Tamiflu (Oseltamivir): Unpublished ClinicalTrials.gov Records => 51% (23 out of 45)
Tamsulosin >75% unpublished
Dabigatran >80% unpublished
Agomelatine >80% unpublished
Liraglutide: 68.5% - three times as likely to be disseminated (3.1 to be spec

Re: Concerns over data in key dabigatran trial.
http://www.bmj.com/content/349/bmj.g4747/rr/778288
October 17, 2014.

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