This study examined the relationship between levels of polybrominated diphenyl ether (PBDE) flame retardants measured in serum and biomarkers of oxidative stress and inflammation in a representative sample of the US population from the NHANES 2003-2004 survey. The study found small but statistically significant positive associations between levels of the PBDE congener BDE-153 and two markers of inflammation, alkaline phosphatase and absolute neutrophil count, suggesting that higher BDE-153 exposure may be linked to increased systemic inflammation. No significant associations were observed between PBDE levels and the oxidative stress biomarkers examined. This study provides further evidence from human studies that certain PBDE congeners may induce inflammatory responses.
This study examined the relationship between levels of polybrominated diphenyl ether (PBDE) flame retardants measured in serum and biomarkers of oxidative stress and inflammation in a representative sample of the US population from the NHANES 2003-2004 survey. The study found small but statistically significant positive associations between levels of the PBDE congener BDE-153 and two markers of inflammation, alkaline phosphatase and absolute neutrophil count, suggesting that higher BDE-153 exposure may be linked to increased systemic inflammation. No significant associations were observed between PBDE levels and the oxidative stress biomarkers examined. This study provides further evidence from human studies that certain PBDE congeners may induce inflammatory responses.
Using food as your medicine discusses how diet impacts cancer risk and progression. It notes that 90-95% of cancer cases are due to environmental and lifestyle factors like diet, smoking, alcohol and obesity. Diet can affect cancer through initiation, promotion and anti-promotion pathways. Carcinogens in foods like red meat and certain fats can initiate cancer, while excess calories, fat, protein and sugars can promote tumor growth. Phytonutrients, antioxidants, fiber and a plant-based diet high in fruits and vegetables can help prevent cancer through anti-promotion effects like detoxification and reducing inflammation. Lifestyle changes including a whole foods, plant-based diet are emphasized as the primary way to take control of cancer risk
The document summarizes a discussion on the topic of heredity between a group that includes a tech hater, psychologist, tech guru, and research specialist. It defines heredity as the transmission of qualities from ancestors to descendants through genes. It then provides examples of how heredity influences specific health conditions like cystic fibrosis, fragile X syndrome, and spinal muscular atrophy through statistics on each. The document also discusses how epigenetics can indirectly influence a person's genes through environmental factors.
The document defines 30 key health indicators used by the WHO to measure and analyze population health. Some of the indicators include life expectancy at birth, healthy life expectancy, neonatal mortality rate, maternal mortality ratio, tuberculosis mortality rate, and rates of immunization coverage. The indicators measure longevity, causes of death, access to healthcare, disease burden, and health system resources.
Free radicals are unstable molecules that can damage cells. They are formed through normal metabolic processes but also due to environmental toxins and radiation. The body has antioxidant defenses against free radicals but an excess can lead to oxidative stress and disease. Endogenous free radicals include reactive oxygen species like superoxide, hydrogen peroxide, and hydroxyl radicals produced during metabolism. Exogenous sources include tobacco smoke, drugs, radiation, and air pollution. Free radical damage accumulates with age and is linked to many age-related diseases.
This document discusses various health indicators used to measure morbidity and mortality. It defines key terms like mortality, crude death rate, life expectancy. It also covers morbidity measures like prevalence, incidence and types of morbidity rates. Different rates are explained including infant, child, maternal and other cause-specific mortality rates. The importance and limitations of these indicators in understanding population health are also summarized.
This document discusses the four major types of adult tissues - epithelial, connective, muscle and nervous tissue. It provides details on the classification, structure and functions of each type of tissue. The key points are:
1) Tissues are classified based on structure, composition and function. The four major types are epithelial, connective, muscle and nervous tissue.
2) Epithelial tissues cover surfaces, line organs and form glands. They protect, absorb, secrete and transport. Connective tissues connect, support and protect other tissues. Muscle tissues contract to cause movement and pumping blood. Nervous tissues transmit electrical signals.
3) Each tissue contains different cell types and extracellular matrix to suit their functions.