際際滷s
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This document provides dosage and administration guidelines for Botox injections to treat forehead lines, glabellar lines, and lateral canthal lines. It recommends doses of 20 units for forehead lines, 20 units for glabellar lines, and 24 units for lateral canthal lines. When treating all three areas simultaneously, the recommended total dose is 64 units. It provides instructions for reconstituting Botox and describes injection techniques, including identifying injection sites and ensuring accurate dosing.
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際際滷s
- 1. Priyanka Kalsi Dose, dilution, reconstitution and injection techniques. Botox
- 2. Botox, onabotulinumtoxin A Dose is dependent on the area being tested. Cosmetic dilution and reconstitution processes are same for moderate to severe forehead lines, lateral canthus lines and glabellar lines.
- 3. Dose Forehead 20 units. Lateral canthal 24 units. Glabellar lines 20 units.
- 4. Dose Treat forehead lines in connection with glabellar lines to reduce brow ptosis. The approved dosage for treatment of forehead lines 20 units in conjunction with glabellar lines 20 units is 40 units. For simultaneous treatment of three areas dose is 20+24+20, 20 for forehead, 24 for lateral canthal lines, 20 for glabellar lines, with total dosage of 64 units.
- 5. Dose 40 unit dose provides ef鍖cacy without an increase in side effects, compared with lower dose.
- 6. Dilution table Botox is supplied in 100 units and 50 unit single use vials for reconstitution. Cosmetic should be reconstituted with sterile, preservative free 0.9% sodium chloride injection USP. Once open and reconstituted, use within 24 hrs. Because of lack of preservatives in product and diluent. During the 24 hrs, cosmetic should be stored in a refrigerator at 2 degree Celsius to 8 degree Celsius. 36 F to 46 F. Vials are for single use only.
- 7. Dilution instructions for reconstitution. 100 unit vial, 2.50 ml diluent, preservative free 0.9% sodium chloride injection. USP only. Resulting dose 4 units.
- 8. Dilution instructions for reconstitution. 50 unit vial, 1.25 ml, preservative free 0.9% sodium chloride injection and USP only. Resulting dose 4 units.
- 9. Dilution instructions Forehead line treatment is 4 units per 0.1 ml at each of the 鍖ve injection sites. 20 units per 0.5 ml of frontalis muscle. 4 units per 0.1 into each of the 鍖ve glabellar lines. 20 units per 0.5 ml. Total 40 units per 1.0 ml.
- 10. Dilution instructions for reconstitution. Lateral canthal lines, 4 units per 0.1 ml. There is 6 injection sites, 3 on each site, for a total dose of 24 units per 0.6 ml.
- 11. Injection techniques. For moderate to severe frontal lines. When identifying the location of the appropriate injection sites in the frontalis muscle, assess the overall relationship between size of forehead and distribution of frontalis muscle activity.
- 12. Injection techniques. Locate the horizontal treatment dose, by light palpating of forehead at rest and maximum eyebrow elevation. Superior margin of frontalis activity, approximately 1 cm above the most superior frontal crease. Lower treatment row: midway between superior margin of frontalis activity and eyebrow at least 2cm above the eyebrow. Upper treatment row: midway between the superior margin of frontalis activity and lower treatment row.
- 13. Injection techniques Inject 4 units/0.1ml reconstituted Botox solution into 5 sites in the frontalis muscle for a total of 20 units/0.5 ml. Place the 5 injections at intersections of horizontal treatment rows and vertical landmarks. On the lower treatment row, at the midline of face and 0.5 to 1.5 cm medial to palpated temporal fusion temporal crest, repeat on other site. On the upper treatment row, midway between lateral and medial sites on the lower treatment row, repeat for other site.
- 14. Injection techniques For moderate to severe glabellar lines. 4 units of 0.1 ml, into each of the 5 sites. 2 in corrugator, 1 in procerus for a total of 20 units. To reduce the risk of ptosis. Avoid injection near levator palpebral superioris, especially in patient with large brow depressor complexes.
- 15. Injection techniques Lateral corrugator injections should be placed at least 1 cm above the bony supraorbital ridge. Ensure the injected vol and dose are accurate and where feasible kept to a minimum. Dont inject Botox closer than one cm above the central eyebrow.
- 16. Injection techniques Injection should be given with needle level tip up and oriented away from the eye. 4 units 0.1 ml, each of the the 6 sites. ( 3 injections per site.). Total dose of 24 units.
- 17. Two approved injection patterns. If lines are both above and below the lateral canthus. First injection at least 1.5 cm to 2 cm, temporal to the lateral canthus and just temporal to the lateral orbital rim. Second injection, 1 to 1.5 cm above the 鍖rst injection site and an approximately 30 degree angle medially. Third injection 1 cm to 1.5 cm below the 鍖rst injection site and at 30 degree angle medially.
- 18. If lines are primarily below the lateral canthus. First injection 1.5 to 2 cm temporal to the lateral canthus and just temporal to the lateral orbital rim. Inject along a line that angles from antero inferior to superior posterior. Ensure the most anterior injection is lateral to a line drawn vertically from lateral canthus. Remember to keep the most inferior injection superior to maxillary prominence.