The Three Mile Island accident in 1979 was the most significant nuclear accident in U.S. history. It began with a minor malfunction that caused the reactor to shut down, but a relief valve failed to close. Over almost 16 hours, operators struggled to determine the problem and solution. Small amounts of radioactive gases were released, leading to the voluntary evacuation of 140,000 people within a 20-mile radius, though maximum radiation exposure was less than 100 mrem. The cleanup took 12 years and cost $973 million, and the plant did not restart until 1985. While no health effects were found, it highlighted needs for improved operator training and safety systems.